المؤلفون: Basagni, Filippo, Ortega, Jose A, Bertozzi, Sine M, Armirotti, Andrea, Summa, Maria, Bertorelli, Rosalia, Bartolini, Manuela, Mellor, Ian R, Bedeschi, Martina, Bottegoni, Giovanni, Lembo, Vittorio, Minarini, Anna, Cavalli, Andrea, Rosini, Michela

المساهمون: Basagni, Filippo, Ortega, Jose A, Bertozzi, Sine M, Armirotti, Andrea, Summa, Maria, Bertorelli, Rosalia, Bartolini, Manuela, Mellor, Ian R, Bedeschi, Martina, Bottegoni, Giovanni, Lembo, Vittorio, Minarini, Anna, Cavalli, Andrea, Rosini, Michela

مصطلحات موضوعية: Alzheimer's disease, Cholinesterase, Drug conjugate, Galantamine, Memantine, NMDAR

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001082168700001; volume:261; firstpage:115803; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11576/2726305; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85171477376

الاتاحة: https://hdl.handle.net/11576/2726305
https://doi.org/10.1016/j.ejmech.2023.115803

المؤلفون: ALNasser, Maryam N., AlSaadi, Ayman M., Whitby, Alison, Kim, Dong Hyun, Mellor, Ian R., Carter, Wayne G.

المساهمون: Lamponi, Stefania

مصطلحات موضوعية: acai berry, antioxidant, Euterpe oleracea, excitotoxicity, L-glutamate, neuroprotection, nutraceuticals

Relation: https://nottingham-repository.worktribe.com/output/19789018; Life; Volume 13; Issue 4; https://nottingham-repository.worktribe.com/file/19789018/1/Acai%20Berry%20%28Euterpe%20sp.%29%20Extracts%20Are%20Neuroprotective%20against%20L-Glutamate-Induced%20Toxicity%20by%20Limiting%20Mitochondrial%20Dysfunction%20and%20Cellular%20Redox%20Stress

الاتاحة: https://doi.org/10.3390/life13041019
https://nottingham-repository.worktribe.com/file/19789018/1/Acai%20Berry%20%28Euterpe%20sp.%29%20Extracts%20Are%20Neuroprotective%20against%20L-Glutamate-Induced%20Toxicity%20by%20Limiting%20Mitochondrial%20Dysfunction%20and%20Cellular%20Redox%20Stress
https://nottingham-repository.worktribe.com/output/19789018

المؤلفون: James, Laura, Reynolds, Andrew M., Mellor, Ian R., Davies, T. G. Emyr

مصطلحات موضوعية: Chemical Health and Safety, Health, Toxicology and Mutagenesis, Toxicology

Relation: https://nottingham-repository.worktribe.com/output/18817535; Toxics; Volume 11; Issue 3; https://nottingham-repository.worktribe.com/file/18817535/1/A%20Sublethal%20Concentration%20of%20Sulfoxaflor%20Has%20Minimal%20Impact%20on%20Buff-Tailed%20Bumblebee%20%28Bombus%20terrestris%29%20Locomotor%20Behaviour%20under%20Aversive%20Conditioning

الاتاحة: https://doi.org/10.3390/toxics11030279
https://nottingham-repository.worktribe.com/file/18817535/1/A%20Sublethal%20Concentration%20of%20Sulfoxaflor%20Has%20Minimal%20Impact%20on%20Buff-Tailed%20Bumblebee%20%28Bombus%20terrestris%29%20Locomotor%20Behaviour%20under%20Aversive%20Conditioning
https://nottingham-repository.worktribe.com/output/18817535

المؤلفون: Casewell, Nicholas R, Petras, Daniel, Card, Daren C, Suranse, Vivek, Mychajliw, Alexis M, Richards, David, Koludarov, Ivan, Albulescu, Laura-Oana, Slagboom, Julien, Hempel, Benjamin-Florian, Ngum, Neville M, Kennerley, Rosalind J, Brocca, Jorge L, Whiteley, Gareth, Harrison, Robert A, Bolton, Fiona M S, Debono, Jordan, Vonk, Freek J, Alföldi, Jessica, Johnson, Jeremy, Karlsson, Elinor K, Lindblad-Toh, Kerstin, Mellor, Ian R, Süssmuth, Roderich D, Fry, Bryan G, Kuruppu, Sanjaya, Hodgson, Wayne C, Kool, Jeroen, Castoe, Todd A, Barnes, Ian, Sunagar, Kartik, Undheim, Eivind A B, Turvey, Samuel T

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(51):25745-25755

مصطلحات موضوعية: convergent molecular evolution, gene duplication, genotype phenotype, kallikrein toxin, venom systems

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401532
https://doi.org/10.1073/pnas.1906117116
https://uu.diva-portal.org/smash/get/diva2:1383529/FULLTEXT01.pdf

المؤلفون: Richards, David P., Patel, Rohit N., Duce, Ian R., Khambay, Bhupinder P. S., Birkett, Michael A., Pickett, John A., Mellor, Ian R.

مصطلحات موضوعية: Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science

Relation: https://nottingham-repository.worktribe.com/output/12624562; Molecules; Volume 27; Issue 20; https://nottingham-repository.worktribe.com/file/12624562/1/%28%E2%88%92%29-Adaline%20from%20the%20Adalia%20Genus%20of%20Ladybirds%20Is%20a%20Potent%20Antagonist%20of%20Insect%20and%20Specific%20Mammalian%20Nicotinic%20Acetylcholine%20Receptors

الاتاحة: https://doi.org/10.3390/molecules27207074
https://nottingham-repository.worktribe.com/file/12624562/1/%28%E2%88%92%29-Adaline%20from%20the%20Adalia%20Genus%20of%20Ladybirds%20Is%20a%20Potent%20Antagonist%20of%20Insect%20and%20Specific%20Mammalian%20Nicotinic%20Acetylcholine%20Receptors
https://nottingham-repository.worktribe.com/output/12624562

المؤلفون: AL Nasser, Maryam N., Mellor, Ian R., Carter, Wayne G.

مصطلحات موضوعية: Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science

Relation: https://nottingham-repository.worktribe.com/output/9579753; Molecules; Volume 27; Issue 15; https://nottingham-repository.worktribe.com/file/9579753/1/Preliminary%20Assessment%20of%20the%20Nutraceutical%20Potential%20of%20Acai%20Berry

الاتاحة: https://doi.org/10.3390/molecules27154891
https://nottingham-repository.worktribe.com/file/9579753/1/Preliminary%20Assessment%20of%20the%20Nutraceutical%20Potential%20of%20Acai%20Berry
https://nottingham-repository.worktribe.com/output/9579753

المؤلفون: Al-Nasser, Maryam N., Mellor, Ian R., Carter, Wayne G.

مصطلحات موضوعية: excitotoxicity, L-glutamate, mitochondrial dysfunction, neurodegeneration, neuroin-29 flammation, oxidative stress, protein aggregation

Relation: https://nottingham-repository.worktribe.com/output/7835654; Brain Sciences; Volume 12; Issue 5; https://nottingham-repository.worktribe.com/file/7835654/1/Is%20L-Glutamate%20Toxic%20to%20Neurons%20and%20Thereby%20Contributes%20to%20Neuronal%20Loss%20and%20Neurodegeneration%3F%20A%20Systematic%20Review

الاتاحة: https://doi.org/10.3390/brainsci12050577
https://nottingham-repository.worktribe.com/file/7835654/1/Is%20L-Glutamate%20Toxic%20to%20Neurons%20and%20Thereby%20Contributes%20to%20Neuronal%20Loss%20and%20Neurodegeneration%3F%20A%20Systematic%20Review
https://nottingham-repository.worktribe.com/output/7835654

المؤلفون: Ngum, Neville M., Aziz, Muhammad Y. A., Latif, M. Liaque, Wall, Richard J., Duce, Ian R., Mellor, Ian R., Aziz, Muhammad Y.A., Mohammed Latif, Liaque

مصطلحات موضوعية: Physiology

Relation: https://nottingham-repository.worktribe.com/output/7766571; Journal of Physiology; Volume 600; Issue 10; Pagination 2499-2513

الاتاحة: https://doi.org/10.1113/JP283055
https://nottingham-repository.worktribe.com/file/7766571/1/The%20Journal%20Of%20Physiology%20-%202022%20-%20Ngum%20-%20Non%20%3F%20Canonical%20Endogenous%20Expression%20Of%20Voltage%20%3F%20Gated%20Sodium%20Channel%20NaV1%207
https://nottingham-repository.worktribe.com/output/7766571

المؤلفون: Mellor, Ian R.

مصطلحات موضوعية: 590, Wasp venum toxins

الاتاحة: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335759

المؤلفون: Mohamad, Mohamad Haiqal Nizar, Abu, Izuddin Fahmy, Fazel, Muhammad Fattah, Agarwal, Renu, Iezhitsa, Igor, Juliana, Norsham, Mellor, Ian R., Franzyk, Henrik

مصطلحات موضوعية: Pharmacology (medical), Pharmacology

Relation: https://nottingham-repository.worktribe.com/output/7171801; Frontiers in Pharmacology; Volume 12

الاتاحة: https://doi.org/10.3389/fphar.2021.798794
https://nottingham-repository.worktribe.com/file/7171801/1/Neuroprotection%20Against%20NMDA-Induced%20Retinal%20Damage%20by%20Philanthotoxin-343%20Involves%20Reduced%20Nitrosative%20Stress
https://nottingham-repository.worktribe.com/output/7171801

المؤلفون: Luck, Victoria L., Richards, David P., Shaikh, Ashif Y., Franzyk, Henrik, Mellor, Ian R.

Relation: https://nottingham-repository.worktribe.com/output/7024222; Molecules; Volume 26; Issue 22; https://nottingham-repository.worktribe.com/file/7024222/1/The%20Effects%20of%20Structural%20Alterations%20in%20the%20Polyamine%20and%20Amino%20Acid%20Moieties%20of%20Philanthotoxins%20on%20Nicotinic%20Acetylcholine%20Receptor%20Inhibition%20in%20the%20Locust,%20Schistocerca%20gregaria

الاتاحة: https://doi.org/10.3390/molecules26227007
https://nottingham-repository.worktribe.com/file/7024222/1/The%20Effects%20of%20Structural%20Alterations%20in%20the%20Polyamine%20and%20Amino%20Acid%20Moieties%20of%20Philanthotoxins%20on%20Nicotinic%20Acetylcholine%20Receptor%20Inhibition%20in%20the%20Locust,%20Schistocerca%20gregaria
https://nottingham-repository.worktribe.com/output/7024222

المؤلفون: Fazel, Muhammad Fattah, Abu, Izuddin Fahmy, Mohamad, Mohamad Haiqal Nizar, Agarwal, Renu, Iezhitsa, Igor, Bakar, Nor Salmah, Juliana, Norsham, Mellor, Ian R., Franzyk, Henrik

المساهمون: Badea, Tudor C

مصطلحات موضوعية: Multidisciplinary

Relation: https://nottingham-repository.worktribe.com/output/4817169; PLOS ONE; Volume 15; Issue 7

الاتاحة: https://doi.org/10.1371/journal.pone.0236450
https://nottingham-repository.worktribe.com/file/4817169/1/Philanthotoxin-343
https://nottingham-repository.worktribe.com/output/4817169

المؤلفون: Thompson, Andrew J., Verdin, Paul S., Burton, Mark J., Davies, T. G.Emyr, Williamson, Martin S., Field, Linda M., Baines, Richard A., Mellor, Ian R., Duce, Ian R.

مصطلحات موضوعية: Insect Science, Biochemistry, Molecular Biology

Relation: https://nottingham-repository.worktribe.com/output/4489260; Insect Biochemistry and Molecular Biology; Volume 122

الاتاحة: https://doi.org/10.1016/j.ibmb.2020.103388
https://nottingham-repository.worktribe.com/file/4489260/1/Thompson%20Et%20Al%20Manuscript%20Accepted%20IB-D-20-00043
https://nottingham-repository.worktribe.com/output/4489260

المؤلفون: Patel, Rohit N., Richards, David P., Duce, Ian R., Birkett, Michael A., Sattelle, David B., Mellor, Ian R.

Relation: https://nottingham-repository.worktribe.com/output/4445539; Pesticide Biochemistry and Physiology; Volume 166; https://nottingham-repository.worktribe.com/file/4445539/1/Patel%20Et%20Al%202020%20Accepted%20Manuscript

الاتاحة: https://doi.org/10.1016/j.pestbp.2020.104561
https://nottingham-repository.worktribe.com/file/4445539/1/Patel%20Et%20Al%202020%20Accepted%20Manuscript
https://nottingham-repository.worktribe.com/output/4445539

المؤلفون: Rosini, Michela, Simoni, Elena, Caporaso, Roberta, Basagni, Filippo, Catanzaro, Michele, Abu, Izuddin F., Fagiani, Francesca, Fusco, Federica, Masuzzo, Sara, Albani, Diego, Lanni, Cristina, Mellor, Ian R., Minarini, Anna

مصطلحات موضوعية: Organic Chemistry, Pharmacology, Drug Discovery, General Medicine

Relation: https://nottingham-repository.worktribe.com/output/2563325; European Journal of Medicinal Chemistry; Volume 180; Pagination 111-120

الاتاحة: https://doi.org/10.1016/j.ejmech.2019.07.011
https://nottingham-repository.worktribe.com/file/2563325/1/Rosini%20Et%20Al%202019%20EJMC%20Accepted
https://nottingham-repository.worktribe.com/output/2563325

المؤلفون: Kachel, Hamid S., Franzyk, Henrik, Mellor, Ian R.

مصطلحات موضوعية: nicotinic acetylcholine receptor, philanthotoxin, antagonism, open-channel block, Xenopus oocytes, two-electrode voltage clamp

Relation: https://nottingham-repository.worktribe.com/output/2228225; Journal of Medicinal Chemistry; Volume 62; Issue 13; Pagination 6214-6222; https://nottingham-repository.worktribe.com/file/2228225/1/Kachel%20Et%20Al%20Accepted%2005-06-2019

الاتاحة: https://doi.org/10.1021/acs.jmedchem.9b00519
https://nottingham-repository.worktribe.com/file/2228225/1/Kachel%20Et%20Al%20Accepted%2005-06-2019
https://nottingham-repository.worktribe.com/output/2228225

المؤلفون: Knight, Helen, Koromina, Maria, Flitton, Miles, Blockley, Alix, Mellor, Ian R

Relation: https://nottingham-repository.worktribe.com/output/3462227; Scientific Reports; Volume 9; https://nottingham-repository.worktribe.com/file/3462227/1/s41598-019-55635-4

الاتاحة: https://doi.org/10.1038/s41598-019-55635-4
https://nottingham-repository.worktribe.com/file/3462227/1/s41598-019-55635-4
https://nottingham-repository.worktribe.com/output/3462227

المؤلفون: Furutani, Shogo, Ihara, Makoto, Lees, Kristin, Buckingham, Steven D., Partridge, Frederick A., David, Jonathan A., Patel, Rohit, Warchal, Scott, Mellor, Ian R., Matsuda, Kazuhiko, Sattelle, David B.

المساهمون: University of St Andrews. School of Biology

مصطلحات موضوعية: Glutamate-gated-chloride channel, Tick Ixodes scapularis, Ivermectin, Okaramine B, Acaricide, QH301 Biology, QD Chemistry, RC Internal medicine, NDAS, SDG 3 - Good Health and Well-being, QH301, QD, RC

وصف الملف: application/pdf

Relation: International Journal for Parasitology: Drugs and Drug Resistance; Furutani , S , Ihara , M , Lees , K , Buckingham , S D , Partridge , F A , David , J A , Patel , R , Warchal , S , Mellor , I R , Matsuda , K & Sattelle , D B 2018 , ' The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis , a tick vector of Lyme disease ' , International Journal for Parasitology: Drugs and Drug Resistance , vol. 8 , no. 2 , pp. 350-360 . https://doi.org/10.1016/j.ijpddr.2018.06.001; PURE: 253278079; PURE UUID: ddeb8c3c-cae3-4b5c-8fba-9f965da0a7a1; RIS: urn:009802C4974617CBF029FD6389A6F0AA; Scopus: 85048949133; WOS: 000438125200023; http://hdl.handle.net/10023/14714; https://doi.org/10.1016/j.ijpddr.2018.06.001

الاتاحة: http://hdl.handle.net/10023/14714
https://doi.org/10.1016/j.ijpddr.2018.06.001

المؤلفون: Koromina, Maria, Flitton, Miles, Mellor, Ian R., Knight, Helen M.

مصطلحات موضوعية: Kainate receptors, GluK4, deletion allele, cognition, mood disorders

Relation: https://nottingham-repository.worktribe.com/output/903989; World Journal of Biological Psychiatry; Volume 20; Issue 5; Pagination 393-401; https://nottingham-repository.worktribe.com/file/903989/1/Submitted_Accepted_manuscriptSWBP-2017-0169.pdf

الاتاحة: https://doi.org/10.1080/15622975.2017.1417637
https://nottingham-repository.worktribe.com/file/903989/1/Submitted_Accepted_manuscriptSWBP-2017-0169.pdf
https://nottingham-repository.worktribe.com/output/903989

المؤلفون: Simioni, Elena, Bartolini, Manuela, Abu, Izuddin Fahmy, Blockley, Alix, Gotti, Cecilia, Bottegoni, Giovanni, Caporaso, Roberta, Bergamini, Christian, Andrisano, Vincenza, Cavalli, Andrea, Mellor, Ian R., Minarini, Anna

مصطلحات موضوعية: Alzheimer’s disease, Nicotinic receptors, Acetylcholinesterase inhibitors, Multitarget compounds, Amyloid aggregation

Relation: https://nottingham-repository.worktribe.com/output/867422; Future Medicinal Chemistry; Volume 9; Issue 10

الاتاحة: https://doi.org/10.4155/fmc-2017-0039
https://nottingham-repository.worktribe.com/file/867422/1/Rosini_Manuscript_revised.pdf
https://nottingham-repository.worktribe.com/output/867422