المؤلفون: Meijuan Jiang (1463935), Shuiyu Lu (1447027), Sanjay Telu (1447024), Victor W. Pike (203776)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Chemical Sciences not elsewhere classified, therefore deemed necessary, shown unstable quantification, positron emission tomography, imaging phosphodiesterase 4d, empirically derived values, low nm range, empirical quantitative structure, high inhibitory potency, fourteen new compounds, 2 , 11 , successful pet radioligands, high target affinity, 50 , p1 – p4, pde4d pet radioligands, pet radioligands, r <, n <, nm )], binding affinity, [< sup, >< sup, predict compounds

Relation: https://figshare.com/articles/journal_contribution/An_Empirical_Quantitative_Structure-Activity_Relationship_Equation_Assists_the_Discovery_of_High-Affinity_Phosphodiesterase_4D_Inhibitors_as_Leads_to_PET_Radioligands/21834148

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01745.s001

المؤلفون: Chengcheng Zhou (1401142), Chen Peng (429537), Chunzi Shi (9376882), Meijuan Jiang (1463935), Joe H. C. Chau (8398713), Zhiyang Liu (4332328), Haotian Bai (3121383), Ryan T. K. Kwok (7345682), Jacky W. Y. Lam (7345685), Yuxin Shi (547600), Ben Zhong Tang (1272294)

مصطلحات موضوعية: Microbiology, Genetics, Neuroscience, Pharmacology, Biotechnology, Evolutionary Biology, Ecology, Infectious Diseases, Plant Biology, Chemical Sciences not elsewhere classified, Mitochondria-Specific Aggregation-I., IQ-TPE -2O IQ-Cm, fungus-infected rabbit model, subcellular organelle mitochondrion, AIEgen, PDT strategy, aggregation-induced emission charac., reactive 1 O 2, Selective Photodynamic Killing, IQ-TPA, mitochondria, fungi

Relation: https://figshare.com/articles/journal_contribution/Mitochondria-Specific_Aggregation-Induced_Emission_Luminogens_for_Selective_Photodynamic_Killing_of_Fungi_and_Efficacious_Treatment_of_Keratitis/14869213

الاتاحة: https://doi.org/10.1021/acsnano.1c03508.s001

المؤلفون: Meijuan Jiang (1463935), Shuiyu Lu (1447027), Sanjay Telu (1447024), Victor W. Pike (203776)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Chemical Sciences not elsewhere classified, therefore deemed necessary, shown unstable quantification, positron emission tomography, imaging phosphodiesterase 4d, empirically derived values, low nm range, empirical quantitative structure, high inhibitory potency, fourteen new compounds, 2 , 11 , successful pet radioligands, high target affinity, 50 , p1 – p4, pde4d pet radioligands, pet radioligands, r <, n <, nm )], binding affinity, [< sup, >< sup, predict compounds

Relation: https://figshare.com/articles/dataset/An_Empirical_Quantitative_Structure-Activity_Relationship_Equation_Assists_the_Discovery_of_High-Affinity_Phosphodiesterase_4D_Inhibitors_as_Leads_to_PET_Radioligands/21834151

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01745.s002