المؤلفون: Madison L. Doolittle, Brittany A. Eckhardt, Stephanie J. Vos, Sarah Grain, Jennifer L. Rowsey, Ming Ruan, Dominik Saul, Joshua N. Farr, Megan M. Weivoda, Sundeep Khosla, David G. Monroe

المصدر: JBMR Plus, Vol 7, Iss 10, Pp n/a-n/a (2023)

مصطلحات موضوعية: ESTROGENS AND SELECTIVE ESTROGEN RECEPTOR MODULATOR, GENETIC ANIMAL MODELS, OSTEOCLASTS, OSTEOPOROSIS, SEX STEROIDS, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2473-4039

URL الوصول: https://doaj.org/article/fce9a970aa3344afb432ff2b7082076c

المؤلفون: Rachelle W. Johnson, Megan M. Weivoda

المصدر: JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)

مصطلحات موضوعية: Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2473-4039

URL الوصول: https://doaj.org/article/903feb2cdbae4416be191e51d293716c

المؤلفون: Megan M. Weivoda, Chee Kian Chew, David G. Monroe, Joshua N. Farr, Elizabeth J. Atkinson, Jennifer R. Geske, Brittany Eckhardt, Brianne Thicke, Ming Ruan, Amanda J. Tweed, Louise K. McCready, Robert A. Rizza, Aleksey Matveyenko, Moustapha Kassem, Thomas Levin Andersen, Adrian Vella, Matthew T. Drake, Bart L. Clarke, Merry Jo Oursler, Sundeep Khosla

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/801d47b97fd94e109d4d6b51b08d8de3

المؤلفون: Sam W. Z. Olechnowicz, Megan M. Weivoda, Seint T. Lwin, Szi K. Leung, Sarah Gooding, Guido Nador, Muhammed Kassim Javaid, Karthik Ramasamy, Srinivasa R. Rao, James R. Edwards, Claire M. Edwards

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/d8afcd0e1a894dd9a3e3bba9c52aefc9

المؤلفون: Megan M Weivoda, Elizabeth W Bradley

المصدر: Journal of Bone and Mineral Research. 38:359-369

مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Orthopedics and Sports Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8b7658b6172d76ca9da3e1b5b0d7e30
https://doi.org/10.1002/jbmr.4773

المؤلفون: Margaret M. Durdan, Ruth D. Azaria, Megan M. Weivoda

المصدر: Semin Cell Dev Biol

مصطلحات موضوعية: Osteoblasts, Human bone, Osteoclasts, Cell Biology, Biology, Article, Bone remodeling, Cell biology, Resorption, Coupling (electronics), medicine.anatomical_structure, Osteoclast, Osteogenesis, medicine, Humans, Bone formation, Bone Remodeling, Bone Resorption, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe967fe396450a5103699bcc9edfe13
https://europepmc.org/articles/PMC8840962/

المؤلفون: Ming Xu, Allyson K Palmer, Husheng Ding, Megan M Weivoda, Tamar Pirtskhalava, Thomas A White, Anna Sepe, Kurt O Johnson, Michael B Stout, Nino Giorgadze, Michael D Jensen, Nathan K LeBrasseur, Tamar Tchkonia, James L Kirkland

المصدر: eLife, Vol 4 (2015)

مصطلحات موضوعية: INK-ATTAC, JAK/STAT, ruxolitinib, Activin A, insulin sensitivity, adipose-derived stem cells, Medicine, Science, Biology (General), QH301-705.5

Relation: https://elifesciences.org/articles/12997; https://doaj.org/toc/2050-084X; e12997; https://doaj.org/article/ec852c46c83c4207854436df1e2e57e8

الاتاحة: https://doi.org/10.7554/eLife.12997
https://doaj.org/article/ec852c46c83c4207854436df1e2e57e8

المؤلفون: Brittany A Negley, McKenzie M Fulcer, Jennifer L Onken, David G. Monroe, Daniel G. Fraser, Joshua N. Farr, Brianne S Thicke, Andre J. Van Wijnen, Megan M. Weivoda, Ruben Aquino-Martinez, Sundeep Khosla

المصدر: Journal of Bone and Mineral Research. 34:135-144

مصطلحات موضوعية: 0301 basic medicine, Aging, Endocrinology, Diabetes and Metabolism, Retinoic acid, 030209 endocrinology & metabolism, Biology, Article, Bone remodeling, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, microRNA, medicine, Animals, Humans, Orthopedics and Sports Medicine, Orphan receptor, Regulation of gene expression, Messenger RNA, Osteoblasts, Nuclear Receptor Subfamily 1, Group F, Member 2, Cell Differentiation, Osteoblast, Cell biology, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Osteoporosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c9332b10e22cbe5d2f1a09ad392b04
https://doi.org/10.1002/jbmr.3586

المؤلفون: Bart O. Williams, Alan K. Howe, Merry Jo Oursler, Larry Pederson, Ming Ruan, Christine M Hachfeld, Rachel A Davey, Megan M. Weivoda, Yasuhiro Kobayashi, Sundeep Khosla, Jennifer J. Westendorf, Jeffrey D Zajac

المصدر: Journal of Bone and Mineral Research. 34:1546-1548

مصطلحات موضوعية: musculoskeletal diseases, NFATC Transcription Factors, Chemistry, Endocrinology, Diabetes and Metabolism, Wnt signaling pathway, A Kinase Anchor Proteins, Osteoclasts, Cell Differentiation, Cyclic AMP-Dependent Protein Kinases, Article, Cell biology, Enzyme Activation, Mice, Low Density Lipoprotein Receptor-Related Protein-5, medicine.anatomical_structure, Osteoclast, Low Density Lipoprotein Receptor-Related Protein-6, Wnt3A Protein, medicine, Animals, Orthopedics and Sports Medicine, beta Catenin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df26116b7ec428ea047d420f3c16a4a4
https://doi.org/10.1002/jbmr.3740

المؤلفون: Ming Ruan, Joshua N. Farr, Douglas Forrest, Brianne S Thicke, Megan M. Weivoda, Hong Liu, Kristy M. Nicks, John R. Hawse, Jennifer L Onken, Daniel G. Fraser, Sundeep Khosla, David G. Monroe, Brittany A Negley

المصدر: Journal of Bone and Mineral Research. 33:720-731

مصطلحات موضوعية: 0301 basic medicine, Chemistry, Endocrinology, Diabetes and Metabolism, Wnt signaling pathway, Osteoblast, Bone morphogenetic protein, Bone resorption, Cell biology, Resorption, Bone remodeling, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Osteoprotegerin, Osteoclast, medicine, Orthopedics and Sports Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa8419fd767db37b8aa47fc82d9a0a5d
https://doi.org/10.1002/jbmr.3351

المؤلفون: Sundeep Khosla, Ming Xu, Merry Jo Oursler, David G. Monroe, Tamara Tchkonia, Brittany A Negley, Megan M. Weivoda, Tamar Pirtskhalava, Joshua N. Farr, Daniel G. Fraser, Mikolaj Ogrodnik, Christine M Hachfeld, Robert J. Pignolo, Matthew T. Drake, Jennifer L Onken, Nathan K. LeBrasseur, James L. Kirkland, Jad G Sfeir

المصدر: Nature medicine

مصطلحات موضوعية: 0301 basic medicine, Aging, Disease prevention, Cellular differentiation, Osteoporosis, Osteoclasts, Apoptosis, Weight-Bearing, Mice, Absorptiometry, Photon, 0302 clinical medicine, Cellular Senescence, Caspase 8, Osteocyte, Cell Differentiation, Osteoblast, General Medicine, Flow Cytometry, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancellous Bone, Osteoclast, Drug therapy, medicine.medical_specialty, Transgene, Mice, Transgenic, In Vitro Techniques, Biology, Real-Time Polymerase Chain Reaction, Osteocytes, Article, Bone and Bones, General Biochemistry, Genetics and Molecular Biology, Bone resorption, Proinflammatory cytokine, 03 medical and health sciences, Internal medicine, Nitriles, Cortical Bone, medicine, Animals, Senolytic, Janus Kinases, Osteoblasts, Gene Expression Profiling, beta-Galactosidase, medicine.disease, Pyrimidines, 030104 developmental biology, Endocrinology, Culture Media, Conditioned, Cancer research, Pyrazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063e8b3eb86010ac777721890e2feba3
https://doi.org/10.1038/nm.4385

المؤلفون: Merry Jo Oursler, Stephanie J. Youssef, Megan M. Weivoda

المصدر: Bone. 96:45-50

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Cell type, Histology, Physiology, Endocrinology, Diabetes and Metabolism, Osteoporosis, Osteoarthritis, Biology, Osteocytes, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Rheumatic joint disease, Internal medicine, medicine, Animals, Humans, Disease, Bone formation, Wnt signaling pathway, medicine.disease, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, Organ Specificity, 030220 oncology & carcinogenesis, Osteocyte, Bone Morphogenetic Proteins, Sclerostin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8949ed9115295abaa5a6af33581c97d1
https://doi.org/10.1016/j.bone.2016.11.024

المؤلفون: Diana Jurk, Ewald J. Doornebal, Marissa J. Schafer, Marco Demaria, Ming Xu, Nathan K. LeBrasseur, Tamar Pirtskhalava, Judith Campisi, Grace Casaclang-Verzosa, Folkert Kuipers, Allyson K. Palmer, Michael B. Stout, La Tonya J. Hickson, Theo H. van Dijk, Hajrunisa Cubro, Yi Zhu, Eduardo N. Chini, Aleksey V. Matveyenko, Vesna D. Garovic, Jordan D. Miller, Christine M Hachfeld, Edgar A. Arriaga, Megan M. Weivoda, Larissa G.P. Langhi Prata, Joseph P. Grande, Kurt O. Johnson, Michael D. Jensen, Mikolaj Ogrodnik, Thomas A. White, Tamar Tchkonia, Esther Verkade, Thomas von Zglinicki, James L. Kirkland

المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE), Center for Liver, Digestive and Metabolic Diseases (CLDM), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Aging Cell
Aging Cell, 18(3):12950. Wiley
Aging cell, vol 18, iss 3

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, PHARMACOKINETICS, CLEARANCE, Dasatinib, Adipose tissue, Type 2 diabetes, Inbred C57BL, Cardiovascular, Medical and Health Sciences, Transgenic, Podocyte, quercetin, Mice, 0302 clinical medicine, Adipocytes, cellular senescence, 2.1 Biological and endogenous factors, dasatinib, MACROPHAGES, INSULIN-RESISTANCE, Cell Death, Diabetes, CELLULAR SENESCENCE, PROLIFERATION, Biological Sciences, 3. Good health, medicine.anatomical_structure, DIFFERENTIATION, Adipose Tissue, Adipogenesis, Original Article, Female, type 2 diabetes, medicine.symptom, medicine.medical_specialty, Inflammation, Mice, Transgenic, Biology, Metabolic and Endocrine, adipogenesis, Cell Line, 03 medical and health sciences, Insulin resistance, NAVITOCLAX, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Obesity, Senolytic, Ganciclovir, Cyclin-Dependent Kinase Inhibitor p16, Nutrition, Macrophages, Prevention, aging, Cell Biology, Original Articles, medicine.disease, ADIPOGENESIS, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Glucose, TISSUE, senolytics, Insulin Resistance, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0315bba4a14f3f3ae68a93d1d649e30
https://doi.org/10.1111/acel.12950

المؤلفون: Tamara Tchkonia, Sundeep Khosla, Daniel G. Fraser, Mikolaj Ogrodnik, Nathan K. LeBrasseur, Lynda F. Bonewald, David G. Monroe, Matthew T. Drake, Katharina Jaehn, James L. Kirkland, Haitao Wang, Megan M. Weivoda, Joshua N. Farr, Robert J. Pignolo

المصدر: Journal of Bone and Mineral Research. 31:1920-1929

مصطلحات موضوعية: 0301 basic medicine, Senescence, Cell type, Endocrinology, Diabetes and Metabolism, Cell, Osteoblast, Biology, Cell biology, Bone remodeling, Telomere, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Downregulation and upregulation, Immunology, medicine, Orthopedics and Sports Medicine, Progenitor cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::94c45e32f05805fc3325ac9e465f47d6
https://doi.org/10.1002/jbmr.2892

المؤلفون: Teresa Decklever, Diana Jurk, Geoffry L. Curran, Jennifer J. Westendorf, Ming Xu, Elizabeth W. Bradley, Mikolaj Ogrodnik, Megan M. Weivoda, Tamar Pirtskhalava, Kurt O. Johnson, Tamar Tchkonia, Soyun M. Hwang, Val J. Lowe, James L. Kirkland

المصدر: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

مصطلحات موضوعية: 0301 basic medicine, Aging, Pathology, medicine.medical_specialty, Arthritis, Knee region, Osteoarthritis, Injections, Intra-Articular, 03 medical and health sciences, 0302 clinical medicine, Mechanical allodynia, Ear Cartilage, In vivo, Fluorodeoxyglucose F18, Bioluminescence imaging, Medicine, Animals, Cellular Senescence, business.industry, Senolytics, Brief Report, Fluorodeoxyglucose, Fibroblasts, medicine.disease, beta-Galactosidase, Stifle, Transplantation, Mice, Inbred C57BL, 030104 developmental biology, Positron-Emission Tomography, Luminescent Measurements, Geriatrics and Gerontology, Cell transplantation, Radiopharmaceuticals, business, Cell aging, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5adb48f3d0e0124719e7d75d365be4
http://europepmc.org/articles/PMC5861939

المؤلفون: Jeffrey D. Neighbors, Megan M. Weivoda, Raymond J. Hohl, Craig H. Kuder, David F. Wiemer, Ying Zhang, Junjia Zhu

المصدر: Lipids. 50:1195-1207

مصطلحات موضوعية: Agonist, Cell Survival, medicine.drug_class, Recombinant Fusion Proteins, Biology, Pharmacology, Hydroxylation, Biochemistry, Article, chemistry.chemical_compound, Cell Line, Tumor, Stilbenes, polycyclic compounds, medicine, Humans, Protein Interaction Domains and Motifs, Liver X receptor, Glutathione Transferase, Liver X Receptors, Cholesterol, Anticholesteremic Agents, Organic Chemistry, Biological Transport, Transporter, Cell Biology, Metabolism, Orphan Nuclear Receptors, Antineoplastic Agents, Phytogenic, Hydroxycholesterols, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Kinetics, ATP Binding Cassette Transporter 1, chemistry, Drug Resistance, Neoplasm, Cell culture, lipids (amino acids, peptides, and proteins), Efflux, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cb1cc3db61232ff1bb9dad71a3a50c
https://doi.org/10.1007/s11745-015-4083-z

المؤلفون: Merry Jo Oursler, Ming Ruan, Jeffrey D Zajac, Megan M. Weivoda, Alan K. Howe, Larry Pederson, Jennifer J. Westendorf, Christine M Hachfeld, Bart O. Williams, Yasuhiro Kobayashi, Sundeep Khosla, Rachel A Davey

المصدر: Journal of Bone and Mineral Research. 31:65-75

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, Beta-catenin, biology, Endocrinology, Diabetes and Metabolism, Cellular differentiation, Wnt signaling pathway, LRP6, Osteoblast, LRP5, Cell biology, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Osteoclast, Cancer research, medicine, biology.protein, Orthopedics and Sports Medicine, Protein kinase A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::10fca5b3912efce6dd5121e9ef939585
https://doi.org/10.1002/jbmr.2599

المؤلفون: Rachel A Davey, Larry Pederson, Merry Jo Oursler, Ming Ruan, Christine M Hachfeld, Jennifer J. Westendorf, Megan M. Weivoda, Jeffrey D Zajac, Sundeep Khosla

المصدر: Journal of Bone and Mineral Research. 31:76-85

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, medicine.medical_specialty, Chemistry, Endocrinology, Diabetes and Metabolism, Osteoblast, Endoglin, Bone morphogenetic protein 2, Bone resorption, Resorption, Bone remodeling, Bone morphogenetic protein 7, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Osteoclast, Internal medicine, medicine, Orthopedics and Sports Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0c52226dd5fc8487dec83aba16aebb3c
https://doi.org/10.1002/jbmr.2586

المؤلفون: Bettina M. Weigand, Christine M Hachfeld, Ming Xu, Joshua N. Farr, Xiaonan Hou, Vesna D. Garovic, Jennifer L Onken, Larissa G.P. Langhi, Tamar Pirtskhalava, Hajrunisa Cubro, Ravinder J. Singh, S. John Weroha, Megan M. Weivoda, Mikolaj Ogrodnik, Kurt O. Johnson, Keisuke Ejima, Gene B. Hubbard, Laura J. Niedernhofer, Grace C Verzosa, Diana Jurk, James L. Kirkland, Paul D. Robbins, Moritz Weigl, Christina L. Inman, Jordan D. Miller, Daniel G. Fraser, David B. Allison, Nino Giorgadze, Sundeep Khosla, Yuji Ikeno, Allyson K. Palmer, Tamara Tchkonia, Nathan K. LeBrasseur

المصدر: Nature medicine

مصطلحات موضوعية: 0301 basic medicine, Senescence, Cell Transplantation, Longevity, Dasatinib, Physiology, Adipose tissue, frailty, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, Article, Proinflammatory cytokine, 03 medical and health sciences, Stress, Physiological, Medicine, Animals, Secretion, Senolytic, Survival analysis, Cellular Senescence, business.industry, aging, General Medicine, Survival Analysis, Mice, Inbred C57BL, 030104 developmental biology, Adipose Tissue, Ageing, Cytokines, Quercetin, Inflammation Mediators, business, Explant culture, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02db7172651264fd5240a5fe961df9ae
https://pubmed.ncbi.nlm.nih.gov/30292430

المؤلفون: Joshua N, Farr, Megan M, Weivoda, Kristy M, Nicks, Daniel G, Fraser, Brittany A, Negley, Jennifer L, Onken, Brianne S, Thicke, Ming, Ruan, Hong, Liu, Douglas, Forrest, John R, Hawse, Sundeep, Khosla, David G, Monroe

المصدر: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33(4)

مصطلحات موضوعية: Mice, Knockout, Mice, Osteoblasts, Osteogenesis, Animals, Nuclear Receptor Subfamily 1, Group F, Member 2, Cell Differentiation, Bone Resorption, Wnt Signaling Pathway, Article, Cell Line

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::7f1b63dfc025c2e5699e835def31e1a6
https://pubmed.ncbi.nlm.nih.gov/29206307