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    المساهمون: Deutsches Zentrum für Lungenforschung, Bundesministerium für Bildung und Forschung

    المصدر: Clinical Science ; volume 139, issue 01, page 15-27 ; ISSN 0143-5221 1470-8736

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    المؤلفون: Lee, Matthew M.Y., Masri, Ahmad, Nassif, Michael E., Barriales-Villa, Roberto, Abraham, Theodore P., Claggett, Brian L., Coats, Caroline J., Gimeno, Juan Ramón, Kulac, Ian J., Landsteiner, Isabela, Ma, Changsheng, Maron, Martin S., Olivotto, Iacopo, Owens, Anjali T., Solomon, Scott D., Veselka, Josef, Jacoby, Daniel L., Heitner, Stephen B., Kupfer, Stuart, Malik, Fady I., Meng, Lisa, Wohltman, Amy, Lewis, Gregory D., Wang, Andrew, Sherrid, Mark V, Kelly, Jacob P, Marian, Ali J, Owens, Anjali Tiku, Wever-Pinzon, Omar, Owens, David, Wheeler, Matthew T, Nagueh, Sherif F, Rader, Florian, McGrew, Frank A, Wong, Timothy, O'Neill, Thomas, Bach, Richard G, Martinez, Matthew, Lakdawala, Neal K, Collado, Elias, Turer, Aslan, Desai Y, Milind, Hussain, Zainal, Tower-Rader, Albree F, Hannawi, Bashar, Geske, Jeffrey, Saberi, Sara, Phelan, Dermot, Kramer, Christopher, Sarswat, Nitasha, Ahmad, Ferhaan, Choudhury, Lubna, Markowitz, Jeremy S, Sen, Sounok, Bering, Patrick, Maron, Martin S, Jani, Sandeep, Brinkley, Douglas, Naidu, Srihari, Maurer, Mathew S, Moss, Noah, Bilen, Ozlem, Silva Enciso, Jorge, Fraser, Robert, Akinboboye, Olakunle, Asher, Craig, Emani, Sitaramesh, Sharma, Abhinav, Fermin, David, Lyle, Melissa, Raymer, David, Darlington, Andrew, Resnic, Frederic, Nielsen, Christopher D, Metra, Marco, Musumeci, Beatrice, Emdin, Michele, Targetti, Mattia, Canepa, Marco, Michels, Michelle, Knackstedt, Christian, Amin, Ahmad S., Barriales Villa, Roberto, Garcia Pavia, Pablo, Gimeno Blanes, Juan Ramon, Hidalgo Urbano, Rafael Jesus, Rincon Diaz, Luis Miguel, Ripoll Vera, Tomas Vicente V, Garcia Alvarez, Ana, Zemanek, David, Jensen, MortenK, Mogensen, Jens, Thune, Jens J, Bundgaard, Henning, Charron, Philippe, Trochu, Jean-Noel, Habib, Gilbert, Lhermusier, Thibault, Reant, Patricia, Hagege, Albert A, Logeart, Damien, Mitrovic, Veselin, Edelmann, Frank, Seidler, Tim, Meder, Benjamin, Schulze, Paul Christian, Stoerk, Stefan, Bekfani, Tarek, Rassaf, Tienush, Merkely, Bela, Arad, Michael, Halabi, Majdi, Zwas, Donna, Piltz, Xavier, Paz, Offir, Habib, Manhal, Dudek, Dariusz, Oreziak, Artur, Wojakowski, Wojciech, Toste Batista, Alexandra M, Mesquita Bastos, Jose Adelino, Elliott, Perry M, Mahmod, Masliza, Coats, Caroline, Cooper, Robert, Bradlow, William, Pantazis, Antonios, Tome Esteban, Maria Teresa, McGinnis, Shaina, Campain, Joseph, Cocca-Spofford, Diane, Giverts, Ilya, Griskowitz, Catherine, Newlands, Chloe, Moreno, Fabely Moreno

    وصف الملف: text

    Relation: https://eprints.gla.ac.uk/342146/1/342146.pdf; Lee, M. M.Y. et al. (2024) Aficamten and cardiopulmonary exercise test performance: a substudy of the SEQUOIA-HCM randomized clinical trial. JAMA Cardiology , 9(11), pp. 990-1000. (doi:10.1001/jamacardio.2024.2781 ) (PMID:39230885)

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    المساهمون: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition CHU Pitié Salpêtrière (IHU ICAN), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre National de Recherche en Génomique Humaine (CNRGH), Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire d'excellence en GENomique MEDicale (GENMED), Fondation Jean Dausset - Centre d’Etudes du Polymorphisme Humain Paris (CEPH), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), National Institutes of Health, ANR-10-LABX-0013,GENMED,Medical Genomics(2010)

    المصدر: ISSN: 1061-4036.

    Relation: info:eu-repo/semantics/altIdentifier/pmid/39572784; PUBMED: 39572784; PUBMEDCENTRAL: PMC11631763

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    المساهمون: Institute for Molecular Medicine Finland, Genomics of Neurological and Neuropsychiatric Disorders, Complex Disease Genetics, Helsinki Institute of Life Science HiLIFE, University of Helsinki, HUS Heart and Lung Center, Department of Medicine, Clinicum, Kardiologian yksikkö, Centre of Excellence in Complex Disease Genetics, Research Programs Unit, Aarno Palotie / Principal Investigator

    وصف الملف: application/pdf

    Relation: We gratefully thank all research participants, as this work would not have been possible without their contributions. Relevant funding sources for the FinnGen, UKB and All of Us datasets are presented in the Supplementary Note. S.J.J. received research support through the Junior Clinical Scientist Fellowship from the Dutch Heart Foundation (03-007-2022-0035), as well as a doctoral fellowship from the Amsterdam UMC. J.T.R. was supported by a research grant from the Aarne Koskelo Foundation. S.K. was supported by the Walter Benjamin Fellowship from the Deutsche Forschungsgemeinschaft (521832260). L.F.J.M.W. was supported by the Amsterdam UMC YTF, Dutch Heart Foundation Student Grant and the AFIP foundation. P.T.E. was supported by funding from the National Institutes of Health (1RO1HL092577, 1R01HL157635, 5R01HL139731), by a grant from the American Heart Association (18SFRN34110082) and from the European Union (MAESTRIA 965286). This work was further supported by a grant from the National Institutes of Health (1K08HL153937) and a grant from the American Heart Association (862032) to K.G.A. C.R.B. was supported by funding from the Dutch Heart Foundation (CVON 2018-30 PREDICT2) and the Pathfinder Cardiogenomics programme of the European Innovation Council of the European Union (DCM-NEXT). A.A.M., D.R.K. and Y.M.P. were supported by funding from the PSIDER programme of the Netherlands Organisation for Health Research and Development (ZonMW; project 40-46800-98-018). T.N. was supported by grants from the Sigrid Juselius Foundation, the Finnish Foundation for Cardiovascular Research and the Finnish Research Council (grants 321351 and 354447). This work was supported by a grant from the GENMED Laboratory of Excellence on Medical Genomics (ANR-10-LABX-0013)-a research program managed by the National Research Agency (ANR) as part of the French Investment for the Future; Aviesan-ITMO Genetique-Genomique-Bioinformatique (ResDiCard: Resolving diagnostic deadlock in cardiomyopathies) and the Societe Francaise de Cardiologie/Federation Francaise de Cardiologie; the SFB-TR19 registry was supported by the Deutsche Forschungsgemeinschaft (DFG). The Study of Health in Pomerania (SHIP) is part of the Community Medicine Research net of the University of Greifswald, Germany, funded by the Federal Ministry of Education and Research (grants 01ZZ9603, 01ZZ0103, and 01ZZ0403); the Ministry of Cultural Affairs and the Social Ministry of the Federal State of Mecklenburg-West Pomerania; and grants from the German Center for Cardiovascular Research (DZHK). The KORA study was initiated and financed by the Helmholtz Zentrum Munchen-German Research Center for Environmental Health, funded by the German Federal Ministry of Education and Research (BMBF) and by the State of Bavaria. KORA research was supported at the Munich Center of Health Sciences (MC-Health), Ludwig-Maximilians-Universitat, as part of LMUinnovativ. D.A.T. is supported by the 'EPIDEMIOM-VTE' Senior Chair from the Initiative of Excellence of the University of Bordeaux. This research is based on data from the Million Veteran Program, Office of Research and Development, Veterans Health Administration, and was supported by award I01-BX003362 to P.T. and K.-M.C. This publication does not represent the views of the Department of Veteran Affairs or the United States Government. This work was also supported by the Sir Jules Thorn Charitable Trust (21JTA), Medical Research Council (UK), British Heart Foundation (RE/18/4/34215, SP/17/11/32885), the NIHR Imperial College Biomedical Research Centre, Pathfinder Cardiogenomics programme of the European Innovation Council of the European Union (DCM-NEXT) (101115416) to J.S.W.; http://hdl.handle.net/10138/588659; 001360254300001

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    المؤلفون: Coats, Caroline J., Masri, Ahmad, Nassif, Michael E., Barriales‐Villa, Roberto, Arad, Michael, Cardim, Nuno, Choudhury, Lubna, Claggett, Brian, Düngen, Hans‐Dirk, Garcia‐Pavia, Pablo, Hagège, Albert A., Januzzi, James L., Lee, Matthew M. Y., Lewis, Gregory D., Ma, Chang‐Sheng, Maron, Martin S., Michael Miao, Zi, Michels, Michelle, Olivotto, Iacopo, Oreziak, Artur, Owens, Anjali T., Spertus, John A., Solomon, Scott D., Tfelt‐Hansen, Jacob, van Sinttruije, Marion, Veselka, Josef, Watkins, Hugh, Jacoby, Daniel L., German, Polina, Heitner, Stephen B., Kupfer, Stuart, Lutz, Justin D., Malik, Fady I., Meng, Lisa, Wohltman, Amy, Abraham, Theodore P., Zhang, Yuhui, Yang, Haibo, Shao, Chunli, Yuan, Zuyi, Zeng, Qingchun, Li, Xiaodong, Wang, Yushi, Shu, Yan, Chen, Mulei, Tao, Ling, Li, Xinli, Wang, Jingfeng, Yu, Zaixin, Cheng, Xiang, Hong, Kui, Zemanek, David, Bundgaard, Henning, Thune, Jens, Jensen, Morten, Mogensen, Jens, Habib, Gilbert, Charron, Philippe, Lhermusier, Thibault, Trochu, Jean‐Noël, Reant, Patricia, Logeart, Damien, Mitrovic, Veselin, Bekfani, Tarek, Edelmann, Frank, Seidler, Tim, Meder, Benjamin, Christian Schulze, Paul, Stoerk, Stephan, Rassaf, Tienush, Merkely, Bela, Zfat‐Zwas, Donna, Halabi, Majdi, Paz, Offir, Piltz, Xavier, Metra, Marco, Canepa, Marco, Musumeci, Beatrice, Emdin, Michele, Amin, Ahmad, Knackstedt, Christian, Wojakowski, Wojciech, Dudek, Dariusz, Toste, Alexandra, Mesquita Bastos, José, Ramón Gimeno Blanes, Juan, Jesus Hidalgo Urbano, Rafael, Garcia Alvarez, Ana, Miguel Rincón Diaz, Luis, Vicente Ripoll Vera, Tomas, Elliott, Perry, Greater Glasgow, NHS., Cooper, Rob, Heart, Liverpool, Mahmod, Masliza, Pantazis, Antonis, Teresa Tome Esteban, Maria, Health, Oregon, Marian, Ali, Owens, David, McGrew, Frank, Bach, Richard, Wever‐Pinzon, Omar, Collado, Elias, Turer, Aslan, Hannawi, Bashar, Geske, Jeffrey, Heart, Penn, Symanski, John, Heart, Sanger, Kramer, Christopher, Sarswat, Nitasha, Ahmad, Ferhaan, Markowitz, Jeremy, Lakdawala, Neal, Jani, Sandeep, Brinkley, Marshall, Bilen, Ozlem, Asher, Craig, Emani, Sitaramesh, Sharma, Abhinav, Fermin, David, Lyle, Melissa, Raymer, David, Darlington, Andrew, Nielsen, Christopher, Wang, Andrew, Nagueh, Sherif, Martinez, Matthew, Desai, Milind, Tower‐Rader, Albree, Kelly, Jacob, Heart, Alaska, Rader, Florian, Sen, Sounok, Bering, Patrick, Maurer, Mathew, Mitter, Sumeet, Sherrid, Mark, Wong, Timothy, Hussain, Zainal, Saberi, Sara, Naidu, Srihari, Silva Enciso, Jorge

    وصف الملف: text

    Relation: https://eprints.gla.ac.uk/337074/1/337074.pdf; Coats, C. J. et al. (2024) Dosing and safety profile of aficamten in symptomatic obstructive hypertrophic cardiomyopathy: results from from SEQUOIA‐HCM. Journal of the American Heart Association , 13(5), e035993. (doi:10.1161/JAHA.124.035993 ) (PMID:39056349)

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