المؤلفون: Zhongwen Lei, Yijun Yang, Yang Xiang

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 12 (2025)

مصطلحات موضوعية: organoids, mechanisms of disease, drug screening, regenerative medicine, tissue engineering, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2024.1501829/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/b32814934d264ebd9c415cb22bed8ced

المؤلفون: Krivitsky, Adva, Paunović, Nevena, Klein, Karina, Coulter, Fergal Brian, Schleich, Sarah, Karol, Agnieszka Anna, Bauer, Aline, Krivitsky, Vadim, Lohmann, Victoria, Carril, Paula Cendoya, Bao, Yinyin, von Rechenberg, Brigitte, Halin, Cornelia, Studart, André R, Franzen, Daniel, Leroux, Jean-Christophe

المصدر: Krivitsky, Adva; Paunović, Nevena; Klein, Karina; Coulter, Fergal Brian; Schleich, Sarah; Karol, Agnieszka Anna; Bauer, Aline; Krivitsky, Vadim; Lohmann, Victoria; Carril, Paula Cendoya; Bao, Yinyin; von Rechenberg, Brigitte; Halin, Cornelia; Studart, André R; Franzen, Daniel; Leroux, Jean-Christophe (2025). 3D printed drug-eluting stents: Toward personalized therapy for airway stenosis. Journal of Controlled Release, 377:553-562.

مصطلحات موضوعية: Clinic for Pneumology, Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266779/1/1_s2.0_S0168365924007764_main.pdf; info:pmid/39557216; urn:issn:0168-3659

الاتاحة: https://www.zora.uzh.ch/id/eprint/266779/
https://www.zora.uzh.ch/id/eprint/266779/1/1_s2.0_S0168365924007764_main.pdf
https://doi.org/10.1016/j.jconrel.2024.11.031

المؤلفون: Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel Shao Weng Tan, Wai Leong Tam

المصدر: Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)

مصطلحات موضوعية: Non-small-cell lung cancer, Functional genomics, Mechanisms of disease, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/d7f9b649903749499dd3d17fb11e06b1

المؤلفون: Minoia, Melania, 1984, Quintana-Cordero, Jany, 1992, Jetzinger, Katharina, Kotan, Ilgin Eser, Turnbull, Kathryn Jane, Ciccarelli, Michela, 1993, Masser, Anna E., 1987, Liebers, Dorina, Gouarin, Eloïse, 1999, Czech, Marius, 1998, Hauryliuk, Vasili, Bukau, Bernd, Kramer, Günter, Andréasson, Claes, 1976

المصدر: Nature Communications. 15

مصطلحات موضوعية: Chaperones, Mechanisms of disease, Protein aggregation

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-232552
https://doi.org/10.1038/s41467-024-45645-w

المؤلفون: Sara Carvalhal, Bruno Carmona, Anne-Marie Tassin, João Gonçalves

المصدر: Frontiers in Molecular Biosciences, Vol 11 (2024)

مصطلحات موضوعية: cilium, ciliopathies, molecular mechanisms of disease, rare genetic diseases, organelle, cytoskeleton, signalling, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2024.1421419/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/eff0fb01206d455baf45d40d31d13045

المؤلفون: Olthof, Maurits G L, Hasler, Anita, Valdivieso, Paola, Flück, Martin, Gerber, Christian, Gehrke, Rieke, Klein, Karina, von Rechenberg, Brigitte, Snedeker, Jess G, Wieser, Karl

المصدر: Olthof, Maurits G L; Hasler, Anita; Valdivieso, Paola; Flück, Martin; Gerber, Christian; Gehrke, Rieke; Klein, Karina; von Rechenberg, Brigitte; Snedeker, Jess G; Wieser, Karl (2024). Poly(ADP-Ribose) Polymerases-Inhibitor Talazoparib Inhibits Muscle Atrophy and Fatty Infiltration in a Tendon Release Infraspinatus Sheep Model: A Pilot Study. Metabolites, 14(4):187.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266780/1/metabolites_14_00187.pdf; info:pmid/38668315; urn:issn:2218-1989

الاتاحة: https://www.zora.uzh.ch/id/eprint/266780/
https://www.zora.uzh.ch/id/eprint/266780/1/metabolites_14_00187.pdf
https://doi.org/10.3390/metabo14040187

المؤلفون: Ren, Tianyi, Inglis, Brendan, Darwiche, Salim, Dailey, Hannah L

المصدر: Ren, Tianyi; Inglis, Brendan; Darwiche, Salim; Dailey, Hannah L (2024). Torsion constants and virtual mechanical tests are valid image-based surrogate measures of ovine fracture healing. Journal of Orthopaedic Research, 42(8):1810-1819.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, Center for Applied Biotechnology and Molecular Medicine, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266777/1/Journal_Orthopaedic_Research___2024___Ren___Torsion_constants_and_virtual_mechanical_tests_are_valid_image_based_surrogate.pdf; info:pmid/38491964; urn:issn:0736-0266

الاتاحة: https://www.zora.uzh.ch/id/eprint/266777/
https://www.zora.uzh.ch/id/eprint/266777/1/Journal_Orthopaedic_Research___2024___Ren___Torsion_constants_and_virtual_mechanical_tests_are_valid_image_based_surrogate.pdf
https://doi.org/10.1002/jor.25836

المؤلفون: Orellana, Federica, Grassi, Alberto, Hlushchuk, Ruslan, Wahl, Peter, Nuss, Katja M, Neels, Antonia, Zaffagnini, Stefano, Parrilli, Annapaola

المصدر: Orellana, Federica; Grassi, Alberto; Hlushchuk, Ruslan; Wahl, Peter; Nuss, Katja M; Neels, Antonia; Zaffagnini, Stefano; Parrilli, Annapaola (2024). Revealing the complexity of meniscus microvasculature through 3D visualization and analysis. Scientific Reports, 14(1):10875.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266778/1/41598_2024_Article_61497.pdf; info:pmid/38740845; urn:issn:2045-2322

الاتاحة: https://www.zora.uzh.ch/id/eprint/266778/
https://www.zora.uzh.ch/id/eprint/266778/1/41598_2024_Article_61497.pdf

المؤلفون: Zscherpe, Paula, Kalbitz, Jutta, Weber, Lisa A, Paschke, Reinhard, Mäder, Karsten, von Rechenberg, Brigitte, Cavalleri, Jessika-M V, Meissner, Jessica, Klein, Karina

المصدر: Zscherpe, Paula; Kalbitz, Jutta; Weber, Lisa A; Paschke, Reinhard; Mäder, Karsten; von Rechenberg, Brigitte; Cavalleri, Jessika-M V; Meissner, Jessica; Klein, Karina (2024). Potent drug delivery enhancement of betulinic acid and NVX-207 into equine skin in vitro - a comparison between a novel oxygen flow-assisted transdermal application device and microemulsion gels. BMC Veterinary Research, 20(1):202.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, Center for Applied Biotechnology and Molecular Medicine, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266782/1/12917_2024_Article_4064.pdf; info:pmid/38755639; urn:issn:1746-6148

الاتاحة: https://www.zora.uzh.ch/id/eprint/266782/
https://www.zora.uzh.ch/id/eprint/266782/1/12917_2024_Article_4064.pdf

المؤلفون: Schleich, Sarah, Kronen, Peter, Krivitsky, Adva, Paunović, Nevena, Brian, Coulter Fergal, Karol, Agnieszka Anna, Geks, Anna, Bao, Yinyin, Leroux, Jean-Christophe, von Rechenberg, Brigitte, Franzen, Daniel, Klein, Karina

المصدر: Schleich, Sarah; Kronen, Peter; Krivitsky, Adva; Paunović, Nevena; Brian, Coulter Fergal; Karol, Agnieszka Anna; Geks, Anna; Bao, Yinyin; Leroux, Jean-Christophe; von Rechenberg, Brigitte; Franzen, Daniel; Klein, Karina (2024). Effects of shape and structure of a new 3D-printed personalized bioresorbable tracheal stent on fit and biocompatibility in a rabbit model. PLoS ONE, 19(6):e0300847.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, Center for Applied Biotechnology and Molecular Medicine, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266781/1/pone.0300847.pdf; info:pmid/38917158; urn:issn:1932-6203

الاتاحة: https://www.zora.uzh.ch/id/eprint/266781/
https://www.zora.uzh.ch/id/eprint/266781/1/pone.0300847.pdf
https://doi.org/10.1371/journal.pone.0300847

المؤلفون: Ariyanfar, Alireza, Klein, Karina, von Rechenberg, Brigitte, Darwiche, Salim, Dailey, Hannah L

المصدر: Ariyanfar, Alireza; Klein, Karina; von Rechenberg, Brigitte; Darwiche, Salim; Dailey, Hannah L (2024). Adaptive Image Segmentation Reveals Substantial Cortical Bone Remodeling During Early Fracture Repair. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 12(1):2345165.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, Center for Applied Biotechnology and Molecular Medicine, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266775/1/Adaptive_image_segmentation_reveals_substantial_cortical_bone_remodelling_during_early_fracture_repair.pdf; info:pmid/39036745; urn:issn:2168-1163

الاتاحة: https://www.zora.uzh.ch/id/eprint/266775/
https://www.zora.uzh.ch/id/eprint/266775/1/Adaptive_image_segmentation_reveals_substantial_cortical_bone_remodelling_during_early_fracture_repair.pdf
https://doi.org/10.1080/21681163.2024.2345165

المؤلفون: Schwarz, Simon D, Xu, Jianming, Gunasekera, Kapila, Schürmann, David, Vågbø, Cathrine B, Ferrari, Elena, Slupphaug, Geir, Hottiger, Michael O, Schär, Primo, Steinacher, Roland

المصدر: Schwarz, Simon D; Xu, Jianming; Gunasekera, Kapila; Schürmann, David; Vågbø, Cathrine B; Ferrari, Elena; Slupphaug, Geir; Hottiger, Michael O; Schär, Primo; Steinacher, Roland (2024). Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation. Nature Communications, 15(1):184.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266770/1/41467_2023_Article_44209.pdf; info:pmid/38167803; urn:issn:2041-1723

الاتاحة: https://www.zora.uzh.ch/id/eprint/266770/
https://www.zora.uzh.ch/id/eprint/266770/1/41467_2023_Article_44209.pdf

المؤلفون: Zhang, Qinxin, Xian, Wei, Li, Zilin, Lu, Qian, Chen, Xindi, Ge, Jinli, Tang, Zhiheng, Liu, Bohao, Chen, Zhe, Gao, Xiang, Hottiger, Michael O, Zhang, Peipei, Qiu, Jiazhang, Shao, Feng, Liu, Xiaoyun

المصدر: Zhang, Qinxin; Xian, Wei; Li, Zilin; Lu, Qian; Chen, Xindi; Ge, Jinli; Tang, Zhiheng; Liu, Bohao; Chen, Zhe; Gao, Xiang; Hottiger, Michael O; Zhang, Peipei; Qiu, Jiazhang; Shao, Feng; Liu, Xiaoyun (2024). Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex. Cell Reports, 43(2):113789.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266769/2/1_s2.0_S2211124724001177_main.pdf; info:pmid/38368608; urn:issn:2211-1247

الاتاحة: https://www.zora.uzh.ch/id/eprint/266769/
https://www.zora.uzh.ch/id/eprint/266769/2/1_s2.0_S2211124724001177_main.pdf
https://doi.org/10.1016/j.celrep.2024.113789

المؤلفون: Böhi, Flurina, Hottiger, Michael O

المصدر: Böhi, Flurina; Hottiger, Michael O (2024). Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation. Biomedicines, 12(7):1617.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266768/1/biomedicines_12_01617.pdf; info:pmid/39062190; urn:issn:2227-9059

الاتاحة: https://www.zora.uzh.ch/id/eprint/266768/
https://www.zora.uzh.ch/id/eprint/266768/1/biomedicines_12_01617.pdf
https://doi.org/10.3390/biomedicines12071617

المؤلفون: Manetsch, Patrick, Hottiger, Michael O

المصدر: Manetsch, Patrick; Hottiger, Michael O (2024). Unleashing viral mimicry: A combinatorial strategy to enhance the efficacy of PARP7 inhibitors. BioEssays:e2400087.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/266767/1/BioEssays___2024___Manetsch___Unleashing_viral_mimicry_A_combinatorial_strategy_to_enhance_the_efficacy_of_PARP7.pdf; info:pmid/39502005; urn:issn:0265-9247

الاتاحة: https://www.zora.uzh.ch/id/eprint/266767/
https://www.zora.uzh.ch/id/eprint/266767/1/BioEssays___2024___Manetsch___Unleashing_viral_mimicry_A_combinatorial_strategy_to_enhance_the_efficacy_of_PARP7.pdf
https://doi.org/10.1002/bies.202400087

المؤلفون: van de Kooij, Bert, van der Wal, Fenna J, Rother, Magdalena B, Wiegant, Wouter W, Creixell, Pau, Stout, Merula, Joughin, Brian A, Vornberger, Julia, Altmeyer, Matthias, van Vugt, Marcel A T M, Yaffe, Michael B, van Attikum, Haico

المصدر: van de Kooij, Bert; van der Wal, Fenna J; Rother, Magdalena B; Wiegant, Wouter W; Creixell, Pau; Stout, Merula; Joughin, Brian A; Vornberger, Julia; Altmeyer, Matthias; van Vugt, Marcel A T M; Yaffe, Michael B; van Attikum, Haico (2024). The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks. Nature Communications, 15(1):7076.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/265116/1/ZORA265116.pdf; info:pmid/39152113; urn:issn:2041-1723

الاتاحة: https://www.zora.uzh.ch/id/eprint/265116/
https://www.zora.uzh.ch/id/eprint/265116/1/ZORA265116.pdf

المؤلفون: Talarmin-Gas, Chloé, Smolyakov, Georges, Parisi, Cleo, Scandola, Cyril, Andrianasolonirina, Valérie, Lecoq, Cloé, Houtart, Valentine, Lee, Song-Hua, Adle-Biassette, Homa, Thiébot, Bénédicte, Ganderton, Timothy, Manivet, Philippe

المساهمون: Maladies neurodéveloppementales et neurovasculaires (NeuroDiderot (UMR_S_1141 / U1141)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpital Lariboisière-Fernand-Widal APHP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Plate-forme de bioimagerie ultrastructurale - Ultrastructural BioImaging Core Facility, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), CeleScreen SAS, Laboratoire Analyse, Modélisation et Matériaux pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Funding for this work was provided by AP-HP to P.M. and C.T-G, and equipment support was provided by the French Government Programme Investissements d’Avenir France BioImaging (FBI, N° ANR-10-INSB-04-01) and the French government (Agence Nationale de la Recherche) Investissement d’Avenir programme, Laboratoire d’Excellence “Integrative Biology of Emerging Infectious Diseases” (ANR-10-LABX-62-IBEID)., ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010)

المصدر: ISSN: 2399-3642 ; Communications Biology ; https://hal.science/hal-04829679 ; Communications Biology, 2024, 7 (1), pp.1398. ⟨10.1038/s42003-024-06967-z⟩.

مصطلحات موضوعية: Experimental models of disease, Mechanisms of disease, Translational research, [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], [CHIM]Chemical Sciences

Relation: info:eu-repo/semantics/altIdentifier/pmid/39462037; PUBMED: 39462037; PUBMEDCENTRAL: PMC11513083

الاتاحة: https://hal.science/hal-04829679
https://hal.science/hal-04829679v1/document
https://hal.science/hal-04829679v1/file/s42003-024-06967-z.pdf
https://doi.org/10.1038/s42003-024-06967-z

المؤلفون: Raote, Ishier, Häkkinen, Hanna-Maria, Vibe, Carine, Broadbent, Katrina, Carolis, Carlo, Ruprecht, Verena, Malhotra, Vivek

مصطلحات موضوعية: Endoplasmic reticulum, Mechanisms of disease

وصف الملف: application/pdf

Relation: Nat Commun. 2024 Apr 24;15(1):3302; info:eu-repo/grantAgreement/EC/H2020/951146; info:eu-repo/grantAgreement/ES/3PN/SEV-2012-0208; info:eu-repo/grantAgreement/ES/1PE/BFU2013-44188-P; info:eu-repo/grantAgreement/ES/3PN/CSD2009-00016; info:eu-repo/grantAgreement/ES/2PE/PID2020-117011GB-I00; info:eu-repo/grantAgreement/ES/3PE/PDC2021-121870-I00; info:eu-repo/grantAgreement/ES/2PE/CEX2019-000910-S; info:eu-repo/grantAgreement/EC/H2020/871124; info:eu-repo/grantAgreement/ES/2PE/PRE2020-095721; http://hdl.handle.net/10230/61031

الاتاحة: http://hdl.handle.net/10230/61031
https://doi.org/10.1038/s41467-024-47004-1

المؤلفون: Medina Dols, Aina, Mola Caminal, Marina, Soriano Tarraga, Carolina, Giralt-Steinhauer, Eva, Lazcano Dobao, Uxue, Fernández-Pérez, Isabel, Jiménez-Balado, Joan, Jiménez Conde, Jordi, Vives Bauzá, Cristòfol

مصطلحات موضوعية: Blood–brain barrier, Epithelial–mesenchymal transition, Mechanisms of disease

وصف الملف: application/pdf

Relation: Cell Death Discov. 2024 Feb 17;10(1):85; http://hdl.handle.net/10230/61344

الاتاحة: http://hdl.handle.net/10230/61344
https://doi.org/10.1038/s41420-024-01857-z

المؤلفون: Richter, Henning, Verlemann, Christine, Jeibmann, Astrid, Martin, Louise F, Luebke, Andreas M, Karol, Agnieszka, Sperling, Michael, Radbruch, Alexander, Karst, Uwe

المصدر: Richter, Henning; Verlemann, Christine; Jeibmann, Astrid; Martin, Louise F; Luebke, Andreas M; Karol, Agnieszka; Sperling, Michael; Radbruch, Alexander; Karst, Uwe (2024). Elemental Bioimaging of Sheep Bone and Articular Cartilage After Single Application of Gadolinium-Based Contrast Agents. Investigative Radiology, 59(4):287-292.

مصطلحات موضوعية: Department of Molecular Mechanisms of Disease, Department of Small Animals, Department of Clinical Diagnostics and Services, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/239433/1/elemental_bioimaging_of_sheep_bone_and_articular.153.pdf; info:pmid/37747456; urn:issn:0020-9996

الاتاحة: https://www.zora.uzh.ch/id/eprint/239433/
https://www.zora.uzh.ch/id/eprint/239433/1/elemental_bioimaging_of_sheep_bone_and_articular.153.pdf
https://doi.org/10.1097/RLI.0000000000001020