المؤلفون: Jong, Robyn M, Van Dis, Erik, Berry, Samuel B, Nguyenla, Xammy, Baltodano, Alexander, Pastenkos, Gabrielle, Xu, Chenling, Fox, Douglas, Yosef, Nir, McWhirter, Sarah M, Stanley, Sarah A

المصدر: The Journal of Immunology. 208(2)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Immunology, Lung, Tuberculosis, Orphan Drug, Immunization, Rare Diseases, Vaccine Related, Emerging Infectious Diseases, Tuberculosis Vaccine, Infectious Diseases, Prevention, Biotechnology, 3.4 Vaccines, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Adjuvants, Immunologic, Animals, CD30 Ligand, Interferon-gamma, Interleukin-17, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, Mycobacterium tuberculosis, Respiratory Mucosa, Th17 Cells, Tuberculosis Vaccines, Tuberculosis, Pulmonary, Vaccination, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0bc1h255
https://escholarship.org/content/qt0bc1h255/qt0bc1h255.pdf

المؤلفون: Nicolai, Christopher J, Wolf, Natalie, Chang, I-Chang, Kirn, Georgia, Marcus, Assaf, Ndubaku, Chudi O, McWhirter, Sarah M, Raulet, David H

المصدر: Science Immunology. 5(45)

مصطلحات موضوعية: Cancer, Rare Diseases, Vaccine Related, Immunization, Prevention, 5.2 Cellular and gene therapies, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Good Health and Well Being, Animals, CD8-Positive T-Lymphocytes, CRISPR-Cas Systems, Interferon Type I, Killer Cells, Natural, Membrane Proteins, Mice, Mice, Congenic, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Neoplasms, Tumor Cells, Cultured

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/13t3q9pr

المؤلفون: Wolf, Natalie K., Blaj, Cristina, Picton, Lora K., Snyder, Gail, Zhang, Li, Nicolai, Christopher J., Ndubaku, Chudi O., McWhirter, Sarah M., Garcia, K. Christopher, Raulet, David H.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2022 May . 119(22), 1-12.

URL الوصول: https://www.jstor.org/stable/27151971

المؤلفون: Luteijn, Rutger D, Zaver, Shivam A, Gowen, Benjamin G, Wyman, Stacia K, Garelis, Nick E, Onia, Liberty, McWhirter, Sarah M, Katibah, George E, Corn, Jacob E, Woodward, Joshua J, Raulet, David H

المصدر: Nature. 573(7774)

مصطلحات موضوعية: Cytosol, Animals, Humans, Inflammation, Nucleotidyltransferases, DNA, Nucleotides, Cyclic, Interferon Regulatory Factor-3, Reduced Folate Carrier Protein, Nucleotides, Cyclic, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8t68m9f4

المؤلفون: Van Dis, Erik, Sogi, Kimberly M, Rae, Chris S, Sivick, Kelsey E, Surh, Natalie H, Leong, Meredith L, Kanne, David B, Metchette, Ken, Leong, Justin J, Bruml, Jacob R, Chen, Vivian, Heydari, Kartoosh, Cadieux, Nathalie, Evans, Tom, McWhirter, Sarah M, Dubensky, Thomas W, Portnoy, Daniel A, Stanley, Sarah A

المصدر: Cell Reports. 23(5)

مصطلحات موضوعية: Biological Sciences, Biodefense, Infectious Diseases, Orphan Drug, Tuberculosis Vaccine, Rare Diseases, Prevention, Vaccine Related, Immunization, Emerging Infectious Diseases, Tuberculosis, 3.4 Vaccines, Infection, Good Health and Well Being, Adjuvants, Immunologic, Animals, BCG Vaccine, Disease Models, Animal, Immunity, Cellular, Membrane Proteins, Mice, Mice, Knockout, Mycobacterium tuberculosis, Th1 Cells, Th17 Cells, Tuberculosis, Pulmonary, Vaccines, Subunit, Th17, cyclic dinucleotides, vaccine adjuvant, Biochemistry and Cell Biology, Medical Physiology, Biological sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7bf5h6xf
https://escholarship.org/content/qt7bf5h6xf/qt7bf5h6xf.pdf

المؤلفون: Fu, Juan, Kanne, David B, Leong, Meredith, Glickman, Laura Hix, McWhirter, Sarah M, Lemmens, Edward, Mechette, Ken, Leong, Justin J, Lauer, Peter, Liu, Weiqun, Sivick, Kelsey E, Zeng, Qi, Soares, Kevin C, Zheng, Lei, Portnoy, Daniel A, Woodward, Joshua J, Pardoll, Drew M, Dubensky, Thomas W, Kim, Young

المصدر: Science Translational Medicine. 7(283)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Vaccine Related, Immunization, Biotechnology, Cancer, Immunotherapy, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, Animals, Antineoplastic Agents, CD8-Positive T-Lymphocytes, Cancer Vaccines, Cell Line, Tumor, Cytosol, Dendritic Cells, Female, Humans, Interferon-gamma, Ligands, Membrane Proteins, Mice, Mice, Inbred BALB C, Mice, Inbred C3H, Mice, Inbred C57BL, Monocytes, NF-kappa B, Neoplasm Transplantation, Phosphates, Programmed Cell Death 1 Receptor, Protein Serine-Threonine Kinases, STAT6 Transcription Factor, Biological Sciences, Medical and Health Sciences, Medical biotechnology, Biomedical engineering

URL الوصول: https://escholarship.org/uc/item/1c28g834

المؤلفون: McWhirter, Sarah M., Fitzgerald, Katherine A., Rosains, Jacqueline, Rowe, Daniel C., Golenbock, Douglas T., Maniatis, Tom

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2004 Jan 01. 101(1), 233-238.

URL الوصول: https://www.jstor.org/stable/3148403

المؤلفون: Monroe, Kathryn M, McWhirter, Sarah M, Vance, Russell E

المصدر: PLOS Pathogens. 5(11)

مصطلحات موضوعية: Emerging Infectious Diseases, Genetics, Pneumonia & Influenza, Infectious Diseases, Pneumonia, Lung, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, Aetiology, Infection, Adaptor Proteins, Signal Transducing, Animals, Cells, Cultured, Cytosol, DEAD Box Protein 58, DEAD-box RNA Helicases, Disease Models, Animal, Host-Pathogen Interactions, Immunity, Innate, Interferon Type I, Interferon-Induced Helicase, IFIH1, Legionella pneumophila, Legionnaires' Disease, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, Signal Transduction, Microbiology, Immunology, Medical Microbiology, Virology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0qx0x6q6
https://escholarship.org/content/qt0qx0x6q6/qt0qx0x6q6.pdf

المؤلفون: McWhirter, Sarah M, Barbalat, Roman, Monroe, Kathryn M, Fontana, Mary F, Hyodo, Mamoru, Joncker, Nathalie T, Ishii, Ken J, Akira, Shizuo, Colonna, Marco, Chen, Zhijian J, Fitzgerald, Katherine A, Hayakawa, Yoshihiro, Vance, Russell E

المصدر: Journal of Experimental Medicine. 206(9)

مصطلحات موضوعية: Vaccine Related, Infectious Diseases, Prevention, Emerging Infectious Diseases, Biodefense, Genetics, Aetiology, 2.1 Biological and endogenous factors, Animals, Cell Line, Tumor, Cyclic GMP, Cytosol, DNA Primers, Electrophoretic Mobility Shift Assay, Enzyme-Linked Immunosorbent Assay, Gene Expression Regulation, Immunity, Innate, Immunoblotting, Interferon Type I, Mice, Oligonucleotide Array Sequence Analysis, Polymerase Chain Reaction, Second Messenger Systems, Medical and Health Sciences, Immunology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9704n6d4

المؤلفون: McWhirter, Sarah M., Pullen, Steven S., Holton, James M., Crute, James J., Kehry, Marilyn R., Alber, Tom

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1999 Jul . 96(15), 8408-8413.

URL الوصول: https://www.jstor.org/stable/48499

المؤلفون: McWhirter, Sarah M., Jefferies, Caroline A.

المساهمون: Arthritis Foundation

المصدر: Immunity ; volume 53, issue 1, page 78-97 ; ISSN 1074-7613

الاتاحة: http://dx.doi.org/10.1016/j.immuni.2020.04.004
https://api.elsevier.com/content/article/PII:S107476132030162X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S107476132030162X?httpAccept=text/plain

المؤلفون: Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.

المصدر: Cell Reports ; volume 29, issue 3, page 785-789 ; ISSN 2211-1247

الاتاحة: https://doi.org/10.1016/j.celrep.2019.09.089
https://api.elsevier.com/content/article/PII:S2211124719312938?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124719312938?httpAccept=text/plain

المؤلفون: Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.

المساهمون: Aduro Biotech, Inc.

المصدر: Cell Reports ; volume 25, issue 11, page 3074-3085.e5 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2018.11.047
https://api.elsevier.com/content/article/PII:S2211124718318102?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124718318102?httpAccept=text/plain

المؤلفون: Meric-Bernstam, Funda, Sweis, Randy F, Kasper, Stefan, Hamid, Omid, Bhatia, Shailender, Dummer, Reinhard, Stradella, Agostina, Long, Georgina V, Spreafico, Anna, Shimizu, Toshio, Steeghs, Neeltje, Luke, Jason J, McWhirter, Sarah M, Müller, Thomas, Nair, Nitya, Lewis, Nancy, Chen, Xinhui, Bean, Andrew, Kattenhorn, Lisa, Pelletier, Marc, Sandhu, Shahneen

المصدر: Meric-Bernstam, Funda; Sweis, Randy F; Kasper, Stefan; Hamid, Omid; Bhatia, Shailender; Dummer, Reinhard; Stradella, Agostina; Long, Georgina V; Spreafico, Anna; Shimizu, Toshio; Steeghs, Neeltje; Luke, Jason J; McWhirter, Sarah M; Müller, Thomas; Nair, Nitya; Lewis, Nancy; Chen, Xinhui; Bean, Andrew; Kattenhorn, Lisa; Pelletier, Marc; Sandhu, Shahneen (2022). Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study. Clinical Cancer Research, 29(1):110-121.

مصطلحات موضوعية: Dermatology Clinic, 610 Medicine & health, Cancer Research, Oncology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/224770/1/960_Meric_Bernstam_F._et_al._Combination_of_the_STING_Agonist_MIW815_and_PD_1_Inhibitor_Spartalizumab_in_Advanced_Metastatic_Solid_Tumors_or_Lymphomas_Clinic_Cancer_Research_2022.pdf; urn:issn:1078-0432

الاتاحة: https://www.zora.uzh.ch/id/eprint/224770/
https://www.zora.uzh.ch/id/eprint/224770/1/960_Meric_Bernstam_F._et_al._Combination_of_the_STING_Agonist_MIW815_and_PD_1_Inhibitor_Spartalizumab_in_Advanced_Metastatic_Solid_Tumors_or_Lymphomas_Clinic_Cancer_Research_2022.pdf

المؤلفون: McWhirter, Sarah M., Barbalat, Roman, Monroe, Kathryn M., Fontana, Mary F., Hyodo, Mamoru, Joncker, Nathalie T., Ishii, Ken J., Akira, Shizuo, Colonna, Marco, Cheng, Zhiliang, Fitzgerald, Katherine A., Hayakawa, Yoshihiro, Vance, Russell E.

المساهمون: Department of Biochemistry and Molecular Pharmacology, Department of Medicine, Division of Infectious Diseases and Immunology

المصدر: The Journal of experimental medicine ; 206 ; 9 ; 1899-911

مصطلحات موضوعية: Animals, Cell Line, Tumor, Cyclic GMP, Cytosol, DNA Primers, Electrophoretic Mobility Shift Assay, Enzyme-Linked Immunosorbent Assay, Gene Expression Regulation, Immunity, Innate, Immunoblotting, Interferon Type I, Mice, Oligonucleotide Array Sequence Analysis, Polymerase Chain Reaction, Second Messenger Systems, Immunology and Infectious Disease

Relation: Link to Article in PubMed; http://dx.doi.org/10.1084/jem.20082874; J Exp Med. 2009 Aug 31;206(9):1899-911. Epub 2009 Aug 3. Link to article on publisher's site; 0022-1007 (Linking); http://hdl.handle.net/20.500.14038/35228; https://escholarship.umassmed.edu/infdis_pp/63; 1901385; infdis_pp/63

الاتاحة: https://doi.org/10.1084/jem.20082874
https://hdl.handle.net/20.500.14038/35228
https://escholarship.umassmed.edu/infdis_pp/63

المؤلفون: McWhirter, Sarah M., Fitzgerald, Katherine A., Rosains, Jacqueline, Rowe, Daniel C., Golenbock, Douglas T., Maniatis, Tom

المساهمون: Department of Medicine, Division of Infectious Diseases and Immunology, Department of Molecular and Cellular Biology

المصدر: Proceedings of the National Academy of Sciences of the United States of America ; 101 ; 1 ; 233-8

مصطلحات موضوعية: Animals, DNA-Binding Proteins, Fibroblasts, Gene Expression, I-kappa B Kinase, Interferon Regulatory Factor-3, Interferon-beta, Mice, Knockout, Phosphorylation, Protein-Serine-Threonine Kinases, Recombinant Proteins, Transcription Factors, Virus Diseases, Immunology and Infectious Disease, Life Sciences, Medicine and Health Sciences

Relation: Link to article in PubMed; http://dx.doi.org/10.1073/pnas.2237236100; Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):233-8. Epub 2003 Dec 16. Link to article on publisher's site; 0027-8424 (Print); http://hdl.handle.net/20.500.14038/34185; https://escholarship.umassmed.edu/gsbs_sp/843; 670499; gsbs_sp/843

الاتاحة: https://doi.org/10.1073/pnas.2237236100
https://hdl.handle.net/20.500.14038/34185
https://escholarship.umassmed.edu/gsbs_sp/843

المؤلفون: Fitzgerald, Katherine A., McWhirter, Sarah M., Faia, Kerrie L., Rowe, Daniel C., Latz, Eicke, Golenbock, Douglas T., Coyle, Anthony J., Liao, Sha-Mei, Maniatis, Tom

المساهمون: Department of Medicine, Division of Infectious Diseases and Immunology, Daniel C. Rowe

المصدر: Nature immunology ; 4 ; 5 ; 491-6

مصطلحات موضوعية: Adaptor Proteins, Vesicular Transport, Chemokine CCL5, DNA-Binding Proteins, Drosophila Proteins, Gene Expression Regulation, Humans, I-kappa B Kinase, Immunity, Natural, Interferon Regulatory Factor-3, Interferon-beta, Membrane Glycoproteins, NF-kappa B, Protein-Serine-Threonine Kinases, RNA Interference, Receptors, Cell Surface, Signal Transduction, Toll-Like Receptor 3, Toll-Like Receptors, Transcription Factors, Virus Diseases, Immunology and Infectious Disease, Life Sciences, Medicine and Health Sciences

Relation: Link to article in PubMed; http://dx.doi.org/10.1038/ni921; Nat Immunol. 2003 May;4(5):491-6. Link to article on publisher's site; 1529-2908 (Print); http://hdl.handle.net/20.500.14038/33621; https://escholarship.umassmed.edu/gsbs_sp/291; 616267; gsbs_sp/291

الاتاحة: https://doi.org/10.1038/ni921
https://hdl.handle.net/20.500.14038/33621
https://escholarship.umassmed.edu/gsbs_sp/291

المؤلفون: tenOever, Benjamin R., Ng, Sze-Ling, Chua, Mark A., McWhirter, Sarah M., García-Sastre, Adolfo, Maniatis, Tom

المصدر: Science, 2007 Mar 01. 315(5816), 1274-1278.

URL الوصول: https://www.jstor.org/stable/20035708

المؤلفون: Abdullah, Mohd Amir F.¹ (AUTHOR), McWhirter, Sarah M.² (AUTHOR), Suo, Zucai^1,3 (AUTHOR) zucai.suo@med.fsu.edu

المصدر: Cells (2073-4409). Feb2023, Vol. 12 Issue 3, p406. 20p.

مصطلحات موضوعية: *HEPATITIS C virus, *IMMUNOMODULATORS, *KINASES, *IMMUNE response, *NATURAL immunity

المؤلفون: Corrales, Leticia, Glickman, Laura Hix, McWhirter, Sarah M, Kanne, David B, Sivick, Kelsey E, Lemmens, Edward, Leong, Justin J, Metchette, Ken, Dubensky, Thomas W, Gajewski, Thomas

المصدر: Journal for ImmunoTherapy of Cancer ; volume 2, issue S3 ; ISSN 2051-1426

الاتاحة: http://dx.doi.org/10.1186/2051-1426-2-s3-o10
http://link.springer.com/content/pdf/10.1186/2051-1426-2-S3-O10.pdf