المؤلفون: Simkin, Dina, Papakis, Vasileios, Bustos, Bernabe I, Ambrosi, Christina M, Ryan, Steven J, Baru, Valeriya, Williams, Luis A, Dempsey, Graham T, McManus, Owen B, Landers, John E, Lubbe, Steven J, George, Alfred L, Kiskinis, Evangelos

المساهمون: Neurology

المصدر: Stem cell reports ; 17 ; 4 ; 993 ; 1008 ; United States

مصطلحات موضوعية: CRISPR/Cas9, KCNQ2, WGS, disease modeling, genome editing, iPSCs, isogenic control lines, mtDNA, on-target insertions/deletions

Relation: Stem Cell Reports; https://doi.org/10.1016/j.stemcr.2022.02.008; Simkin D, Papakis V, Bustos BI, Ambrosi CM, Ryan SJ, Baru V, Williams LA, Dempsey GT, McManus OB, Landers JE, Lubbe SJ, George AL Jr, Kiskinis E. Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls. Stem Cell Reports. 2022 Apr 12;17(4):993-1008. doi:10.1016/j.stemcr.2022.02.008. Epub 2022 Mar 10. PMID: 35276091; PMCID: PMC9023783.; http://hdl.handle.net/20.500.14038/52437

الاتاحة: https://doi.org/10.1016/j.stemcr.2022.02.008
https://hdl.handle.net/20.500.14038/52437

المؤلفون: Borja, Gabriel B., Zhang, Hongkang, Harwood, Benjamin N., Jacques, Jane, Grooms, Jennifer, Chantre, Romina O., Zhang, Dawei, Barnett, Adam, Werley, Christopher A., Lu, Yang, Nagle, Steven F., McManus, Owen B., Dempsey, Graham T.

المساهمون: National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke

المصدر: Frontiers in Molecular Neuroscience ; volume 15 ; ISSN 1662-5099

الاتاحة: http://dx.doi.org/10.3389/fnmol.2022.896320
https://www.frontiersin.org/articles/10.3389/fnmol.2022.896320/full

المؤلفون: Simkin, Dina, Ambrosi, Christina, Marshall, Kelly A., Williams, Luis A., Eisenberg, Jordyn, Gharib, Mennat, Dempsey, Graham T., George, Alfred L., McManus, Owen B., Kiskinis, Evangelos

المصدر: Trends in Pharmacological Sciences ; volume 43, issue 5, page 392-405 ; ISSN 0165-6147

الاتاحة: http://dx.doi.org/10.1016/j.tips.2022.03.001
https://api.elsevier.com/content/article/PII:S0165614722000517?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0165614722000517?httpAccept=text/plain

المؤلفون: Zhang, Hongkang, Moyer, Bryan D., Yu, Violeta, McGivern, Joseph G., Jarosh, Michael, Werley, Christopher A., Hecht, Vivian C., Babcock, Ryan J., Dong, Kevin, Dempsey, Graham T., McManus, Owen B., Hempel, Chris M.

المساهمون: XXXXX

المصدر: SLAS Discovery ; volume 25, issue 5, page 434-446 ; ISSN 2472-5552

الاتاحة: http://dx.doi.org/10.1177/2472555220914532
http://journals.sagepub.com/doi/pdf/10.1177/2472555220914532
http://journals.sagepub.com/doi/full-xml/10.1177/2472555220914532
https://api.elsevier.com/content/article/PII:S2472555222065674?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2472555222065674?httpAccept=text/plain

المؤلفون: McManus, Owen B., Werley, Christopher A., Dempsey, Graham T.

المصدر: Journal of General Physiology ; volume 151, issue 6, page 714-717 ; ISSN 0022-1295 1540-7748

الاتاحة: http://dx.doi.org/10.1085/jgp.201912325
https://rupress.org/jgp/article-pdf/151/6/714/1804072/jgp_201912325.pdf

المؤلفون: Liu, Pin W., Zhang, Hongkang, Werley, Christopher A., Pichler, Monika, Ryan, Steven J., Lewarch, Caitlin L., Jacques, Jane, Grooms, Jennifer, Ferrante, Jean, Li, Guangde, Zhang, Dawei, Bremmer, Nate, Barnett, Adam, Chantre, Romina, Elder, Amy E., Cohen, Adam E., Williams, Luis A., Dempsey, Graham T., McManus, Owen B.

المساهمون: National Institute of Arthritis and Musculoskeletal and Skin Diseases

المصدر: Pain ; ISSN 0304-3959 1872-6623

الاتاحة: http://dx.doi.org/10.1097/j.pain.0000000000003090
https://journals.lww.com/10.1097/j.pain.0000000000003090

المؤلفون: Yu, Haibo, Lin, Zhihong, Mattmann, Margrith E., Zou, Beiyan, Terrenoire, Cecile, Zhang, Hongkang, Wu, Meng, McManus, Owen B., Kass, Robert S., Lindsley, Craig W., Hopkins, Corey R., Li, Min

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2013 May . 110(21), 8732-8737.

URL الوصول: https://www.jstor.org/stable/42656791

المؤلفون: Zhang, Hongkang, Zou, Beiyan, Yu, Haibo, Moretti, Alessandra, Wang, Xiaoying, Yan, Wei, Babcock, Joseph J., Bellin, Milena, McManus, Owen B., Tomaselli, Gordon, Nan, Fajun, Laugwitz, Karl-Ludwig, Li, Min

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2012 Jul . 109(29), 11866-11871.

URL الوصول: https://www.jstor.org/stable/41685168

المؤلفون: Zhu, Yingmin, Lu, Yungang, Qu, Chunrong, Miller, Melissa, Tian, Jinbin, Thakur, Dhananjay P, Zhu, Jinmei, Deng, Zixin, Hu, Xianming, Wu, Meng, McManus, Owen B, Li, Min, Hong, Xuechuan, Zhu, Michael X, Luo, Huai‐Rong

المساهمون: National Institutes of Health, National Natural Science Foundation of China, Natural Science Foundation of Yunnan Province, American Heart Association

المصدر: British Journal of Pharmacology ; volume 172, issue 14, page 3495-3509 ; ISSN 0007-1188 1476-5381

الاتاحة: http://dx.doi.org/10.1111/bph.13140
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fbph.13140
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bph.13140

المؤلفون: Ennis, Elizabeth A., Wright, Jane, Retzlaff, Cassandra L., McManus, Owen B., Lin, Zhinong, Huang, Xiaofang, Wu, Meng, Li, Min, Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R., Blakely, Randy D.

المساهمون: National Center for Advancing Translational Sciences, Alzheimer's Association, National Institute of Mental Health, National Institute of General Medical Sciences

المصدر: ACS Chemical Neuroscience ; volume 6, issue 3, page 417-427 ; ISSN 1948-7193 1948-7193

الاتاحة: http://dx.doi.org/10.1021/cn5001809
https://pubs.acs.org/doi/pdf/10.1021/cn5001809

المؤلفون: Borja, Gabriel B., Shroff, Himali, Upadhyay, Hansini, Liu, Pin W., Baru, Valeriya, Cheng, Yung-Chih, McManus, Owen B., Williams, Luis A., Dempsey, Graham T., Werley, Christopher A.

المصدر: Methods in Molecular Biology ; Channelrhodopsin ; page 109-134 ; ISSN 1064-3745 1940-6029 ; ISBN 9781071608296 9781071608302

الاتاحة: http://dx.doi.org/10.1007/978-1-0716-0830-2_8
http://link.springer.com/content/pdf/10.1007/978-1-0716-0830-2_8

المؤلفون: Zhang, Yalan, Quraishi, Imran H., McClure, Heather, Williams, Luis A., Cheng, YungChih, Kale, Siddharth, Dempsey, Graham T., Agrawal, Sudhir, Gerber, David J., McManus, Owen B., Kaczmarek, Leonard K.

المساهمون: National Institutes of Health

المصدر: The FASEB Journal ; volume 35, issue 12 ; ISSN 0892-6638 1530-6860

الاتاحة: http://dx.doi.org/10.1096/fj.202101356r
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202101356R
https://onlinelibrary.wiley.com/doi/full-xml/10.1096/fj.202101356R

المؤلفون: McManus, Owen B., Rothberg, Brad S.

المصدر: Journal of General Physiology ; volume 144, issue 6, page 499-501 ; ISSN 1540-7748 0022-1295

الاتاحة: http://dx.doi.org/10.1085/jgp.201411306
https://rupress.org/jgp/article-pdf/144/6/499/1794003/jgp_201411306.pdf

المؤلفون: Kaczorowski, Gregory J., McManus, Owen B., Priest, Birgit T., Garcia, Maria L.

المصدر: The Journal of General Physiology ; volume 131, issue 5, page 399-405 ; ISSN 1540-7748 0022-1295

الاتاحة: http://dx.doi.org/10.1085/jgp.200709946
https://rupress.org/jgp/article-pdf/131/5/399/1912861/jgp_200709946.pdf