المؤلفون: Toscano, Giorgia, Höfurthner, Theresa, Nagl, Benjamin, Beier, Andreas, Mayer, Moriz, Geist, Leonhard, McConnell, Darryl B., Weinstabl, Harald, Konrat, Robert, Lichtenecker, Roman J.

المصدر: ChemBioChem ; volume 25, issue 6 ; ISSN 1439-4227 1439-7633

الاتاحة: https://doi.org/10.1002/cbic.202300762

المؤلفون: Beier, Andreas, Platzer, Gerald, Höfurthner, Theresa, Ptaszek, Aleksandra L., Lichtenecker, Roman J., Geist, Leonhard, Fuchs, Julian E., McConnell, Darryl B., Mayer, Moriz, Konrat, Robert

المساهمون: Christian Doppler Forschungsgesellschaft

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 15, page 13187-13196 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.4c01128
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01128

المؤلفون: Tarr, James C., Salovich, James M., Aichinger, Martin, Jeon, KyuOk, Veerasamy, Nagarathanam, Sensintaffar, John L., Arnhof, Heribert, Samwer, Matthias, Christov, Plamen P., Kim, Kwangho, Wunberg, Tobias, Schweifer, Norbert, Trapani, Francesca, Arnold, Allison, Martin, Florian, Zhao, Bin, Miriyala, Nagaraju, Sgubin, Danielle, Fogarty, Stuart, Moore, William J., Stott, Gordon M., Olejniczak, Edward T., Engelhardt, Harald, Rudolph, Dorothea, Lee, Taekyu, McConnell, Darryl B., Fesik, Stephen W.

المساهمون: Basic Energy Sciences, Center for Cancer Research

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 16, page 14370-14393 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.4c01188
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01188

المؤلفون: Gerstberger, Thomas, Berger, Helmut, Büttner, Frank H., Gmachl, Michael, Kessler, Dirk, Koegl, Manfred, Lucas, Simon, Martin, Laetitia J., Mayer, Moriz, McConnell, Darryl B., Mitzner, Sophie, Scholz, Guido, Treu, Matthias, Wolkerstorfer, Bernhard, Zahn, Stephan, Zak, Krzysztof M., Jaeger, Philipp A., Ettmayer, Peter

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 14, page 11701-11711 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.3c02381
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02381

المؤلفون: Gripp, Karen W, Schill, Lisa, Schoyer, Lisa, Stronach, Beth, Bennett, Anton M, Blaser, Susan, Brown, Amanda, Burdine, Rebecca, Burkitt-Wright, Emma, Castel, Pau, Darilek, Sandra, Dias, Alwyn, Dyer, Tuesdi, Ellis, Michelle, Erickson, Gregg, Gelb, Bruce D, Green, Tamar, Gross, Andrea, Ho, Alan, Holder, James Lloyd, Inoue, Shin-Ichi, Jelin, Angie C, Kennedy, Annie, Klein, Richard, Kontaridis, Maria I, Magoulas, Pilar, McConnell, Darryl B, McCormick, Frank, Neel, Benjamin G, Prada, Carlos E, Rauen, Katherine A, Roberts, Amy, Rodriguez-Viciana, Pablo, Rosen, Neal, Rumbaugh, Gavin, Sablina, Anna, Solman, Maja, Tartaglia, Marco, Thomas, Angelica, Timmer, William C, Venkatachalam, Kartik, Walsh, Karin S, Wolters, Pamela L, Yi, Jae-Sung, Zenker, Martin, Ratner, Nancy

المصدر: American journal of medical genetics. Part A. 182(3)

مصطلحات موضوعية: Humans, Genetic Diseases, Inborn, ras Proteins, Mitogen-Activated Protein Kinase Kinases, Signal Transduction, Germ-Line Mutation, Costello syndrome, Noonan syndrome, RASopathy, cardio-facio-cutaneous syndrome, kinases, neurofibromatosis, Rare Diseases, Genetics, Good Health and Well Being, Clinical Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5628r91h

المؤلفون: Kessler, Dirk, McConnell, Darryl B.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2020 Oct . 117(43), 26556-26558.

URL الوصول: https://www.jstor.org/stable/26970596

المؤلفون: Platzer, Gerald, Ptaszek, Aleksandra L., Böttcher, Jark, Fuchs, Julian E., Geist, Leonhard, Braun, Daniel, McConnell, Darryl B., Konrat, Robert, Sánchez‐Murcia, Pedro A., Mayer, Moriz

المصدر: ChemPhysChem ; volume 25, issue 1 ; ISSN 1439-4235 1439-7641

الاتاحة: http://dx.doi.org/10.1002/cphc.202300636

المؤلفون: Höfurthner, Theresa, Toscano, Giorgia, Kontaxis, Georg, Beier, Andreas, Mayer, Moriz, Geist, Leonhard, McConnell, Darryl B., Weinstabl, Harald, Lichtenecker, Roman, Konrat, Robert

المساهمون: Christian Doppler Forschungsgesellschaft, University of Vienna

المصدر: Journal of Biomolecular NMR ; volume 78, issue 1, page 1-8 ; ISSN 0925-2738 1573-5001

الاتاحة: http://dx.doi.org/10.1007/s10858-023-00427-2
https://link.springer.com/content/pdf/10.1007/s10858-023-00427-2.pdf
https://link.springer.com/article/10.1007/s10858-023-00427-2/fulltext.html

المؤلفون: Kim, Dongsung, Herdeis, Lorenz, Rudolph, Dorothea, Zhao, Yulei, Böttcher, Jark, Vides, Alberto, Ayala-Santos, Carlos I., Pourfarjam, Yasin, Cuevas-Navarro, Antonio, Xue, Jenny Y., Mantoulidis, Andreas, Bröker, Joachim, Wunberg, Tobias, Schaaf, Otmar, Popow, Johannes, Wolkerstorfer, Bernhard, Kropatsch, Katrin Gabriele, Qu, Rui, de Stanchina, Elisa, Sang, Ben, Li, Chuanchuan, McConnell, Darryl B., Kraut, Norbert, Lito, Piro

المصدر: Nature ; volume 619, issue 7968, page 160-166 ; ISSN 0028-0836 1476-4687

الاتاحة: http://dx.doi.org/10.1038/s41586-023-06123-3
https://www.nature.com/articles/s41586-023-06123-3.pdf
https://www.nature.com/articles/s41586-023-06123-3

المؤلفون: Kessler, Dirk, Gollner, Andreas, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2020 Feb . 117(7), 3365-3367.

URL الوصول: https://www.jstor.org/stable/26928963

المؤلفون: Kesslera, Dirk, Gmachla, Michael, Mantoulidisa, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Gollner, Andreas, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2019 Aug 01. 116(32), 15823-15829.

URL الوصول: https://www.jstor.org/stable/26848431

المؤلفون: Bröker, Joachim, Waterson, Alex G., Smethurst, Chris, Kessler, Dirk, Böttcher, Jark, Mayer, Moriz, Gmaschitz, Gerhard, Phan, Jason, Little, Andrew, Abbott, Jason R., Sun, Qi, Gmachl, Michael, Rudolph, Dorothea, Arnhof, Heribert, Rumpel, Klaus, Savarese, Fabio, Gerstberger, Thomas, Mischerikow, Nikolai, Treu, Matthias, Herdeis, Lorenz, Wunberg, Tobias, Gollner, Andreas, Weinstabl, Harald, Mantoulidis, Andreas, Krämer, Oliver, McConnell, Darryl B., W. Fesik, Stephen

المساهمون: National Cancer Institute, sterreichische Forschungsf?rderungsgesellschaft, Lustgarten Foundation, National Institutes of Health

المصدر: Journal of Medicinal Chemistry ; volume 65, issue 21, page 14614-14629 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.2c01120
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01120

المؤلفون: Platzer, Gerald, Ptaszek, Aleksandra L., Böttcher, Jark, Fuchs, Julian E., Geist, Leonhard, Braun, Daniel, McConnell, Darryl B., Konrat, Robert, Sánchez‐Murcia, Pedro A., Mayer, Moriz

المصدر: ChemPhysChem ; volume 25, issue 1 ; ISSN 1439-4235 1439-7641

الاتاحة: http://dx.doi.org/10.1002/cphc.202300920

المؤلفون: Farnaby, William, Koegl, Manfred, McConnell, Darryl B., Ciulli, Alessio

المصدر: Farnaby , W , Koegl , M , McConnell , D B & Ciulli , A 2021 , ' Transforming targeted cancer therapy with PROTACs : A forward-looking perspective ' , Current Opinion in Pharmacology , vol. 57 , pp. 175-183 . https://doi.org/10.1016/j.coph.2021.02.009

مصطلحات موضوعية: Targeted protein degradation, PROTACs, Cancer, Bifunctional molecules, Drug discovery, Target selectivity, Drug resistance, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/e64d5fd1-5817-4bed-b8e2-1f1c1fcc0446
https://doi.org/10.1016/j.coph.2021.02.009
https://discovery.dundee.ac.uk/ws/files/57742053/Main_text_revised_1_.pdf
http://www.scopus.com/inward/record.url?scp=85103404664&partnerID=8YFLogxK

المؤلفون: Kessler, Dirk, Mayer, Moriz, Zahn, Stephan K., Zeeb, Markus, Wöhrle, Simon, Bergner, Andreas, Bruchhaus, Jens, Ciftci, Tuncay, Dahmann, Georg, Dettling, Maike, Döbel, Sandra, Fuchs, Julian E., Geist, Leonhard, Hela, Wolfgang, Kofink, Christiane, Kousek, Roland, Moser, Franziska, Puchner, Teresa, Rumpel, Klaus, Scharnweber, Maximilian, Werni, Patrick, Wolkerstorfer, Bernhard, Breitsprecher, Dennis, Baaske, Philipp, Pearson, Mark, McConnell, Darryl B., Böttcher, Jark

المصدر: ChemMedChem ; volume 16, issue 9, page 1420-1424 ; ISSN 1860-7179 1860-7187

الاتاحة: http://dx.doi.org/10.1002/cmdc.202000839
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000839
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cmdc.202000839

المؤلفون: Brüschweiler, Sven, Fuchs, Julian E., Bader, Gerd, McConnell, Darryl B., Konrat, Robert, Mayer, Moriz

المساهمون: Österreichische Nationalstiftung für Forschung, Technologie und Entwicklung, Christian Doppler Forschungsgesellschaft

المصدر: ChemMedChem ; volume 16, issue 23, page 3576-3587 ; ISSN 1860-7179 1860-7187

الاتاحة: http://dx.doi.org/10.1002/cmdc.202100458
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100458
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cmdc.202100458

المؤلفون: Kessler, Dirk, Mayer, Moriz, Zahn, Stephan K., Zeeb, Markus, Wöhrle, Simon, Bergner, Andreas, Bruchhaus, Jens, Ciftci, Tuncay, Dahmann, Georg, Dettling, Maike, Döbel, Sandra, Fuchs, Julian E., Geist, Leonhard, Hela, Wolfgang, Kofink, Christiane, Kousek, Roland, Moser, Franziska, Puchner, Teresa, Rumpel, Klaus, Scharnweber, Maximilian, Werni, Patrick, Wolkerstorfer, Bernhard, Breitsprecher, Dennis, Baaske, Philipp, Pearson, Mark, McConnell, Darryl B., Böttcher, Jark

المصدر: ChemMedChem ; volume 16, issue 9, page 1335-1335 ; ISSN 1860-7179 1860-7187

الاتاحة: http://dx.doi.org/10.1002/cmdc.202100271
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100271
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cmdc.202100271

المؤلفون: Herdeis, Lorenz, Gerlach, Daniel, McConnell, Darryl B., Kessler, Dirk

المساهمون: American Association for Cancer Research

المصدر: Current Opinion in Structural Biology ; volume 71, page 136-147 ; ISSN 0959-440X

الاتاحة: http://dx.doi.org/10.1016/j.sbi.2021.06.013
https://api.elsevier.com/content/article/PII:S0959440X2100097X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0959440X2100097X?httpAccept=text/plain

المؤلفون: Kessler, Dirk, Gerlach, Daniel, Kraut, Norbert, McConnell, Darryl B.

المساهمون: American Association for Cancer Research

المصدر: Current Opinion in Chemical Biology ; volume 62, page 109-118 ; ISSN 1367-5931

الاتاحة: http://dx.doi.org/10.1016/j.cbpa.2021.02.014
https://api.elsevier.com/content/article/PII:S1367593121000363?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1367593121000363?httpAccept=text/plain

المؤلفون: McConnell, Darryl B.

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 22, page 16319-16327 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.1c00975
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00975