المؤلفون: Ryan C Durk, Kamalendra Singh, Ceili A Cornelison, Devendra K Rai, Kayla B Matzek, Maxwell D Leslie, Elizabeth Schafer, Bruno Marchand, Adeyemi Adedeji, Eleftherios Michailidis, Christopher A Dorst, Jennifer Moran, Christie Pautler, Luis L Rodriguez, Mark A McIntosh, Elizabeth Rieder, Stefan G Sarafianos

المصدر: PLoS ONE, Vol 5, Iss 12, p e15049 (2010)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3006429?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/f0122b2af81f4aea9a4ce19a093de893

المؤلفون: Maxwell D. Leslie, Michael A. Parniak, Kelsey N. Boschert, Maritza Puray-Chavez, Karen A. Kirby, Zhengqiang Wang, Andrew D. Huber, Jing Tang, Kamalendra Singh, Hiroaki Mitsuya, Maria Boftsi, Megan A. Sheridan, Stefan G. Sarafianos, Eleftherios Michailidis, Jennifer J. Wolf

المصدر: Antimicrobial Agents and Chemotherapy. 61

مصطلحات موضوعية: 0301 basic medicine, Hepatitis B virus, Hepatitis B virus DNA polymerase, Ribonuclease H, Virus Replication, medicine.disease_cause, Antiviral Agents, Hepatitis B virus PRE beta, 03 medical and health sciences, medicine, Humans, Pharmacology (medical), RNase H, Pharmacology, biology, Chemistry, virus diseases, Hbv replication, Virology, digestive system diseases, NS2-3 protease, 030104 developmental biology, Infectious Diseases, Viral replication, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4107b0ed22f3add7ca93a638eedafd3
https://doi.org/10.1128/aac.00245-17

المؤلفون: Yee Tsuey Ong, Bruno Marchand, Maxwell D. Leslie, Michael A. Parniak, Lisa C. Rohan, Kamalendra Singh, Hiroaki Mitsuya, Karen A. Kirby, Stefan G. Sarafianos, Ariel N. Hagedorn, Eleftherios Michailidis, Emily M. Ryan, Kayla B. Matzek, Eiichi Kodama, Andrew D. Huber

المصدر: Journal of Biological Chemistry. 289:24533-24548

مصطلحات موضوعية: Microbiology, Biochemistry, Cell Line, Nucleoside Reverse Transcriptase Inhibitor, chemistry.chemical_compound, Deoxyadenosine, Catalytic Domain, Nucleotide, Molecular Biology, DNA Primers, chemistry.chemical_classification, Base Sequence, Deoxyadenosines, biology, DNA synthesis, Cell Biology, Surface Plasmon Resonance, Virology, Molecular biology, HIV Reverse Transcriptase, Reverse transcriptase, Kinetics, Terminator (genetics), chemistry, Enzyme inhibitor, biology.protein, Reverse Transcriptase Inhibitors, Nucleoside

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd81594b6d4e05706f748d66fb7e9e52
https://doi.org/10.1074/jbc.m114.562694

المؤلفون: Stefan G. Sarafianos, Kamalendra Singh, Maxwell D. Leslie, Michael A. Parniak, Tanyaradzwa P. Ndongwe, Karen A. Kirby, Tracy L. Fetterly, Christopher A. Dorst, Eleftherios Michailidis, Atsuko Hachiya, Daniel V. Sietsema, Yee Tsuey Ong, Zhengqiang Wang, Bruno Marchand

المصدر: Antimicrobial Agents and Chemotherapy. 56:2048-2061

مصطلحات موضوعية: Models, Molecular, Anti-HIV Agents, Cell Survival, RNase P, Xenotropic murine leukemia virus-related virus, Molecular Sequence Data, Ribonuclease H, DNA Footprinting, Microbial Sensitivity Tests, Biology, urologic and male genital diseases, Crystallography, X-Ray, Antiviral Agents, Virus, Murine leukemia virus, Magnesium, Pharmacology (medical), Amino Acid Sequence, Naphthyridines, RNase H, Polymerase, Pharmacology, Manganese, RNA-Directed DNA Polymerase, Hydrazones, virus diseases, Isoquinolines, biology.organism_classification, Virology, Molecular biology, HIV Reverse Transcriptase, Reverse transcriptase, Infectious Diseases, biology.protein, Reverse Transcriptase Inhibitors, Indicators and Reagents, Moloney murine leukemia virus, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c81ac9a91844651e9881cae8536016
https://doi.org/10.1128/aac.06000-11

المؤلفون: Anthony D. Lucas, Nicolin Bloch, Yee Tsuey Ong, Nathaniel R. Landau, Maritza Puray-Chavez, Eleftherios Michailidis, Stefan G. Sarafianos, Andrew D. Huber, Megan L. Schultz, Maxwell D. Leslie, Karen A. Kirby, Juan Ji

مصطلحات موضوعية: Organophosphonates, Gene Expression, Biology, Virus Replication, Antiviral Agents, Monocytes, Nucleoside Reverse Transcriptase Inhibitor, Cell Line, SAM Domain and HD Domain-Containing Protein 1, Zidovudine, immune system diseases, Genes, Reporter, medicine, Humans, Pharmacology (medical), RNA, Small Interfering, Luciferases, Tenofovir, Monomeric GTP-Binding Proteins, Pharmacology, Adenine, Stavudine, Lamivudine, virus diseases, Virology, Reverse transcriptase, HIV Reverse Transcriptase, Infectious Diseases, Biochemistry, Viral replication, Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors, Host-Pathogen Interactions, HIV-1, Reverse Transcriptase Inhibitors, SAMHD1, medicine.drug, Dideoxynucleotides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca44fbfe5ae1bc82960be94ff6468b0
https://europepmc.org/articles/PMC4136039/

المؤلفون: Hiroaki Mitsuya, Kamalendra Singh, Eiichi Kodama, Ariel N. Hagedorn, Maxwell D. Leslie, Michael A. Parniak, Stefan G. Sarafianos, Tracy L. Fetterly, Eleftherios Michailidis, Bruno Marchand, Karen A. Kirby, Stephen H. Hughes, Victor E. Marquez, Musetta A. Steinbach

المصدر: Antimicrobial agents and chemotherapy. 57(12)

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Deamination, Molecular Conformation, Antiviral Agents, chemistry.chemical_compound, Structure-Activity Relationship, Adenosine deaminase, Deoxyadenosine, immune system diseases, Structure–activity relationship, Humans, Pharmacology (medical), Pharmacology, biology, Deoxyadenosines, Chemistry, Active site, virus diseases, Nuclear magnetic resonance spectroscopy, Reverse transcriptase, HIV Reverse Transcriptase, Kinetics, Infectious Diseases, Biochemistry, biology.protein, HIV-1, Reverse Transcriptase Inhibitors, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6dad788479b3b83ed3f7d25b7b8127
https://pubmed.ncbi.nlm.nih.gov/24100493

المؤلفون: Maxwell D. Leslie, Michael A. Parniak, Eleftherios Michailidis, Yee Tsuey Ong, Karen A. Kirby, Lisa C. Rohan, Hiroaki Mitsuya, Eiichi Kodama, Aaron B. Reeve, Stefan G. Sarafianos, Bruno Marchand, Shinichi Oka, Atsuko Hachiya

المصدر: Antimicrobial agents and chemotherapy. 57(9)

مصطلحات موضوعية: Pharmacology, Drug, Tenofovir, business.industry, media_common.quotation_subject, Salvage therapy, Adenosine, Antiviral Agents, chemistry.chemical_compound, Infectious Diseases, chemistry, Deoxyadenosine, Rilpivirine, Medicine, Pharmacology (medical), business, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, media_common, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf74312da3a02916e0b5e12ad0d99891
https://pubmed.ncbi.nlm.nih.gov/23796932

المؤلفون: Adeyemi O. Adedeji, Elizabeth Rieder, Christie Pautler, Eleftherios Michailidis, Kayla B. Matzek, Bruno Marchand, Luis L. Rodriguez, Mark A. McIntosh, Christopher A. Dorst, Elizabeth A. Schafer, Ryan C. Durk, Stefan G. Sarafianos, Devendra K. Rai, Maxwell D. Leslie, Kamalendra Singh, Ceili A. Cornelison, Jennifer L. Moran

المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e15049 (2010)

مصطلحات موضوعية: Picornavirus, viruses, lcsh:Medicine, Ligands, Virus Replication, Biochemistry, chemistry.chemical_compound, Adenosine Triphosphate, RNA polymerase, Enzyme Inhibitors, lcsh:Science, Luciferases, Polymerase, 2. Zero hunger, 0303 health sciences, Multidisciplinary, biology, Viral Replication Complex, Antivirals, 3. Good health, Enzymes, Nucleic acids, Foot-and-Mouth Disease Virus, Viral Enzymes, Foot-and-mouth disease virus, Research Article, RNA-dependent RNA polymerase, Microbiology, Antiviral Agents, Virus, Catalysis, 03 medical and health sciences, Virology, Animals, Binding site, RNA synthesis, Biology, 030304 developmental biology, Binding Sites, 030306 microbiology, lcsh:R, biology.organism_classification, RNA-Dependent RNA Polymerase, Viral Replication, Kinetics, Viral replication, chemistry, Models, Chemical, Enzyme Structure, biology.protein, Mutagenesis, Site-Directed, RNA, lcsh:Q, Cattle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f48db7bb316807b97c1148f9bdcecf
http://europepmc.org/articles/PMC3006429

المؤلفون: Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno March, Maxwell D Leslie, Andrew D Huber, Yee T Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroaki Mitsuya, Michael A Parniak, Stefan G Sarafianos

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.retrovirology.com/content/pdf/1742-4690-10-65.pdf.

مصطلحات موضوعية: HIV-1, RT, EFdA, K65R Background Human immunodeficiency virus type 1 (HIV-1) reverse

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.423.520; http://www.retrovirology.com/content/pdf/1742-4690-10-65.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.423.520
http://www.retrovirology.com/content/pdf/1742-4690-10-65.pdf

المؤلفون: Atsuko Hachiya, Jacob C. Jackson, Eiichi Kodama, Andrew D. Huber, Eleftherios Michailidis, Emily M. Ryan, Kamalendra Singh, Bruno Marchand, Hiroaki Mitsuya, Stefan G. Sarafianos, Maxwell D. Leslie, Michael A. Parniak, Karen A. Kirby, Yee Tsuey Ong

المصدر: Retrovirology

مصطلحات موضوعية: Tenofovir, Anti-HIV Agents, Human immunodeficiency virus (HIV), Mutation, Missense, Organophosphonates, Drug resistance, Microbial Sensitivity Tests, Biology, medicine.disease_cause, RT, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Deoxyadenosine, Virology, Drug Resistance, Viral, medicine, Potency, Humans, 030304 developmental biology, 0303 health sciences, Deoxyadenosines, 030306 microbiology, Adenine, Research, K65R, Resistance mutation, Reverse transcriptase, HIV Reverse Transcriptase, 3. Good health, Infectious Diseases, chemistry, EFdA, HIV-1, Mutant Proteins, Nucleoside, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebbba356085e8445253a7e65d43e8a4