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1Academic Journal
المؤلفون: Ramya Rajagopal, Maria T. Baltazar, Paul L. Carmichael, Matthew P. Dent, Julia Head, Hequn Li, Iris Muller, Joe Reynolds, Kritika Sadh, Wendy Simpson, Sandrine Spriggs, Andrew White, Predrag Kukic
المصدر: Frontiers in Toxicology, Vol 4 (2022)
مصطلحات موضوعية: DART, NAMs, non-animal alternatives, NGRA, mechanistic evaluation, Toxicology. Poisons, RA1190-1270
وصف الملف: electronic resource
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المؤلفون: Hui Li, Samantha Madnick, He Zhao, Susan Hall, Ali Amin, Matthew P. Dent, Kim Boekelheide
المصدر: Toxicology in Vitro. 91:105624
مصطلحات موضوعية: General Medicine, Toxicology
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المؤلفون: Anne Milcamps, Ingrid Langezaal, Roman Liska, Jenny Odum, Matthew P. Dent, Warren Casey
المصدر: Toxicological Sciences
مصطلحات موضوعية: Prioritization, validation, Transcriptional Activation, Validation study, AcademicSubjects/SCI01040, AcademicSubjects/MED00305, business.industry, specificity test, Concordance, Reproducibility of Results, Test method, Computational biology, endocrine disruption, Toxicology, Control test, Receptors, Androgen, androgen receptor, Androgen Receptor Antagonists, Androgens, Medicine, CALUX, business, Mode of action, Reliability (statistics), Regulatory Science, Risk Assessment, and Decision Making
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المؤلفون: Joe Reynolds, Sarah Hatherell, Stephanie Ryder, Paul Walker, Andrew White, Alistair Middleton, Paul L. Carmichael, Hequn Li, Maria Teresa Baltazar, Matthew P. Dent
المصدر: Toxicological Sciences
مصطلحات موضوعية: 0301 basic medicine, computational modeling, oxidative injury, Alternatives to animal testing, 010501 environmental sciences, Toxicology, Bioinformatics, 01 natural sciences, Xenobiotics, 03 medical and health sciences, chemistry.chemical_compound, alternatives to animal testing, Stress, Physiological, medicine, Animals, Humans, glutathione, Adverse effect, redox signaling, 0105 earth and related environmental sciences, dose-response, Family Characteristics, business.industry, Troglitazone, risk assessment, systems biology, Bayes Theorem, medicine.disease, Featured, Mitochondrial toxicity, 030104 developmental biology, chemistry, inflammation, Consumer Product Safety, Toxicity, Biomarker (medicine), cytotoxicity, Xenobiotic, business, Risk assessment, Biomarkers, medicine.drug
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المؤلفون: Ramya Rajagopal, Maria T. Baltazar, Paul L. Carmichael, Matthew P. Dent, Julia Head, Hequn Li, Iris Muller, Joe Reynolds, Kritika Sadh, Wendy Simpson, Sandrine Spriggs, Andrew White, Predrag Kukic
مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, DART, NAMs, non-animal alternatives, NGRA, mechanistic evaluation
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المؤلفون: Ramya Rajagopal, Maria T. Baltazar, Paul L. Carmichael, Matthew P. Dent, Julia Head, Hequn Li, Iris Muller, Joe Reynolds, Kritika Sadh, Wendy Simpson, Sandrine Spriggs, Andrew White, Predrag Kukic
مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, DART, NAMs, non-animal alternatives, NGRA, mechanistic evaluation
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المؤلفون: Lina Gunnarsson, Bruno Campos, Paul L. Carmichael, Andrew White, John K. Colbourne, Geoff Hodges, Matthew P. Dent, Cecilie Rendal, Imran Shah, Carl Westmoreland, Paul Jennings, Claudia Rivetti, Steve Gutsell, Sharon J. Scott, Aude Kienzler, Ian Sorrel, Emma Butler, Luigi Margiotta-Casaluci, Fiona Sewell, Joshua A. Harrill, Richard S. Judson, Iris Muller, Stewart F. Owen, Timothy E. H. Allen, James B. Brown, Francesco Falciani, Mark R. Viant, Paul J. Russell
المساهمون: Allen, Timothy [0000-0001-7369-0901], Apollo - University of Cambridge Repository, Molecular and Computational Toxicology, AIMMS
المصدر: Toxicology in Vitro, 62:104692, 1-9. Elsevier Limited
Rivetti, C, Allen, T E H, Brown, J B, Butler, E, Carmichael, P L, Colbourne, J K, Dent, M, Falciani, F, Gunnarsson, L, Gutsell, S, Harrill, J A, Hodges, G, Jennings, P, Judson, R, Kienzler, A, Margiotta-Casaluci, L, Muller, I, Owen, S F, Rendal, C, Russell, P J, Scott, S, Sewell, F, Shah, I, Sorrel, I, Viant, M R, Westmoreland, C, White, A & Campos, B 2020, ' Vision of a near future: Bridging the human health–environment divide : Toward an integrated strategy to understand mechanisms across species for chemical safety assessment ', Toxicology in Vitro, vol. 62, 104692, pp. 1-9 . https://doi.org/10.1016/j.tiv.2019.104692مصطلحات موضوعية: 0301 basic medicine, Bridging (networking), Computer science, Context (language use), Environment, Mechanism of action, Toxicology, Risk Assessment, 03 medical and health sciences, Human health, 0302 clinical medicine, Species Specificity, Animals, Humans, Risk assessment, Government, General Medicine, Chemical Safety, Pharmacology and Pharmaceutical Sciences, Hazard, Variety (cybernetics), 030104 developmental biology, Incentive, Risk analysis (engineering), 030220 oncology & carcinogenesis, Generic health relevance, Environmental Health, Cross-species extrapolation
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf
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المؤلفون: Tessa C.A. van Tongeren, Paul L. Carmichael, Matthew P. Dent, Thomas E. Moxon, Ivonne M.C.M. Rietjens, Hequn Li
المصدر: Toxicology in Vitro 73 (2021)
Toxicology in Vitro, 73مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Indoles, Comparator, In vitro/in silico approaches, Animal Testing Alternatives, Toxicology, Models, Biological, Tosyl Compounds, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Internal medicine, Nitriles, medicine, Humans, Anilides, Mode of action, Dietary comparator, Toxicologie, VLAG, Risk assessment, WIMEK, business.industry, Androgen Antagonists, Environmental Exposure, General Medicine, Androgen receptor, 030104 developmental biology, Receptors, Androgen, Human exposure, 030220 oncology & carcinogenesis, Biological Assay, sense organs, 3R compliant method, business
وصف الملف: application/pdf
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المؤلفون: Petra S. Kern, Kirstin Kosemund-Meynen, Maciej Stępnik, Christophe Rousselle, Natalie von Goetz, Janine Ezendam, Gladys Ouedraogo, Ulrike Bernauer, Emilio Benfenati, Mark T. D. Cronin, Carsten Goebel, Qasim Chaudhry, Paul L. Carmichael, Eric Gaffet, Pieter Jan Coenraads, Heli M. Hollnagel, Laurent Bodin, Berit Granum, Corrado L. Galli, Andrew Worth, Vera Rogiers, Matthew P. Dent, Maria Dusinska, Tamara Vanhaecke, Eirini Panteri, Corie A. Ellison
المساهمون: Pharmaceutical and Pharmacological Sciences, Connexin Signalling Research Group, Experimental in vitro toxicology and dermato-cosmetology, Vriendenkring VUB, Institut Jean Lamour (IJL), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Scientific Committee for Consumer Safety (European Commission) (SCCS), Scientific Committee for Consumer Safety (SCCS) (SCCS), Vrije Universiteit Brussel (VUB), Mario Negri Institute- IRCCS, Bundesinstitut für Risikobewertung - Federal Institute for Risk Assessment (BfR), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Unilever-Safety & Environmental Assurance Centre, Unilever, University of Chester, University Medical Center Groningen [Groningen] (UMCG), Liverpool John Moores University (LJMU), Norsk Institutt for Luftforskning (NILU), Procter & Gamble (P&G), National Institute for Public Health and the Environment [Bilthoven] (RIVM), Université de Lorraine (UL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), University of Milan, Norwegian Institute of Public Health [Oslo] (NIPH), Dow Europe GmbH, L'Oréal Recherche France (L'Oréal Recherche), L'OREAL, National and Kapodistrian University of Athens (NKUA), Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Nofer Institute of Occupational Medicine (NIOM), Swiss Federal Office of Public Health, European Commission - Joint Research Centre [Ispra] (JRC), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL), Institut de Chimie du CNRS (INC)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Milano = University of Milan (UNIMI)
المصدر: Toxicology
Toxicology, Elsevier, 2020, 436, pp.152421. ⟨10.1016/j.tox.2020.152421⟩
Toxicology, 2020, 436, pp.152421. ⟨10.1016/j.tox.2020.152421⟩مصطلحات موضوعية: 0301 basic medicine, READ-ACROSS, Next generation risk assessment, media_common.quotation_subject, MESH: Consumer Product Safety, Context (language use), UNCERTAINTY, SUBSTANCES, Cosmetics, Hazard analysis, Toxicology, RS, THRESHOLD, 03 medical and health sciences, Human health, 0302 clinical medicine, TOXICOLOGICAL CONCERN VALUES, Product (category theory), EXPOSURE, Animal testing alternatives, ComputingMilieux_MISCELLANEOUS, media_common, Alternative methods, RISK, CONCERN TTC, IDENTIFICATION, Animal-Free method, Replacement method, MESH: Cosmetics, DEVELOPMENTAL TOXICITY, 030104 developmental biology, Risk analysis (engineering), New approach methodology, Safety assessment, Animal Testing Alternative, Alternative method, Cosmetic Products, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], Risk assessement, Business, Risk assessment, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Carl Westmoreland, Beate Nicol, Thomas E. Moxon, Alexis V Nathanail, Predrag Kukic, Joe Reynolds, Matthew P. Dent, Georgia Reynolds, Jade Houghton, Richard Cubberley, Alistair Middleton, Ruth Pendlington, Mi-Young Lee, Andrew White, Paul L. Carmichael, Mona Delagrange, Sophie Malcomber, Maria Teresa Baltazar, Sarah Hatherell, Sophie Cable, Hequn Li, Tom Cull
المساهمون: Pharmaceutical and Pharmacological Sciences
المصدر: Toxicological Sciences
مصطلحات موضوعية: exposure science, Cmax, Cosmetics, Pharmacology, Toxicology, medicine.disease_cause, Risk Assessment, chemistry.chemical_compound, Animal data, In vivo, Coumarins, Toxicity Tests, Medicine, Animals, Humans, Next-Generation Risk Assessment, Computer Simulation, Regulatory Science, Risk Assessment, and Decision Making, Family Characteristics, business.industry, Coumarins/toxicity, In vitro toxicology, Computational Biology, Coumarin, chemistry, Consumer Product Safety, Lotion, new approach methodologies, business, Risk assessment, Genotoxicity
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المؤلفون: Francis Martin, Paul L. Carmichael, Hequn Li, Matthew P. Dent
المصدر: Toxicological Sciences
مصطلحات موضوعية: 0301 basic medicine, B220, Anti-Androgen, Diindolylmethane, dietary comparison, Context (language use), Food Contamination, Pharmacology, Resveratrol, Toxicology, Animal Testing Alternatives, Dietary Factors in Assessing Anti-Androgen Risk, Models, Biological, in vitro approaches, Dietary Exposure, 03 medical and health sciences, Animal data, chemistry.chemical_compound, 0302 clinical medicine, Genes, Reporter, androgen receptor, Cell Line, Tumor, Medicine, Bioassay, Humans, Luciferases, business.industry, risk assessment, Androgen Antagonists, Androgen receptor, 030104 developmental biology, chemistry, Receptors, Androgen, Biological Assay, Risk assessment, business, 030217 neurology & neurosurgery, Food Analysis
وصف الملف: application/pdf
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المؤلفون: Pedro Amores Da Silva, Hajime Kojima, Rajeshwar P. Verma, Petra S. Kern, Stanley Milstein, Beta Montemayor, Yutaka Kasai, Fanny Boisleve, Jay Ansell, Akihiko Hirose, Masato Hatao, Renata Teixeira Amaral, Julcemara Oliveira, Eric Vaillancourt, Craig Weiss, Andrea Richarz, Rob Taalman, Nashira Vieira O.Reilly Cabral Posada, Matthew P. Dent, Reinhard Kreiling
المصدر: Computational Toxicology. 7:20-26
مصطلحات موضوعية: 0301 basic medicine, Underpinning, Computer science, Health, Toxicology and Mutagenesis, media_common.quotation_subject, 010501 environmental sciences, Toxicology, 01 natural sciences, Cosmetics, Consumer safety, Computer Science Applications, 03 medical and health sciences, 030104 developmental biology, Harm, Risk analysis (engineering), Product (category theory), Cosmetic industry, Risk assessment, 0105 earth and related environmental sciences, media_common
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المؤلفون: Francis Martin, Matthew P. Dent, Kim Boekelheide, Ali Amin, Samantha J. Madnick, Paul L. Carmichael, Marguerite Vantangoli Policelli, Chloe Bars, Hui Li, Susan J. Hall
المصدر: Toxicol In Vitro
مصطلحات موضوعية: Male, Stromal cell, medicine.drug_class, Estrogen receptor, Toxicology, urologic and male genital diseases, Animal Testing Alternatives, Article, Flutamide, Cell Line, chemistry.chemical_compound, Prostate, medicine, Estrogen Receptor beta, Humans, Chemistry, B230, Estrogen Receptor alpha, Androgen Antagonists, Dihydrotestosterone, Hydrogels, General Medicine, Androgen, Coculture Techniques, Cell biology, Androgen receptor, medicine.anatomical_structure, Gene Expression Regulation, Cell culture, Receptors, Androgen, Cytochrome P-450 CYP1B1, Androgens, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Yeyejide Adeleye, Matthew P. Dent, Andrew D. Scott, Sharon J. Scott, Sue Edwards, Melvin E. Andersen, Michael Davies, Beate Nicol, Paul L. Carmichael, Qiang Zhang, Rebecca A. Clewell, Paul Fowler, Carl Westmoreland, Andrew White, Bin Sun, Sophie Malcomber
المصدر: Toxicology. 332:102-111
مصطلحات موضوعية: In Vitro Techniques, Animal Testing Alternatives, Toxicology, Models, Biological, Risk Assessment, Risk Factors, Blueprint, Cell Line, Tumor, Toxicity Tests, Animals, Humans, Medicine, Computer Simulation, No-Observed-Adverse-Effect Level, Dose-Response Relationship, Drug, business.industry, Systems Biology, High-Throughput Screening Assays, Risk analysis (engineering), Consumer Product Safety, Human exposure, Research council, Toxicity, Quercetin, Tumor Suppressor Protein p53, business, Risk assessment, DNA Damage, Signal Transduction
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المؤلفون: Kim Z. Travis, Simon Parry, Richard Billington, James S. Bus, Will Davies, Matthew P. Dent, Shakil A. Saghir, Stuart Creton, Michael J. Bartels, Gabrielle M. Hawksworth
المصدر: Regulatory Toxicology and Pharmacology. 62:241-247
مصطلحات موضوعية: Male, Dose-Response Relationship, Drug, Agrochemical, business.industry, Computer science, Interpretation (philosophy), Guidelines as Topic, General Medicine, Toxicology, Risk Assessment, Rats, Risk analysis (engineering), Research Design, High doses, Animals, Humans, Female, Pharmacokinetics, Relevance (information retrieval), business, Risk assessment, Chemical risk, Blood sampling, Dose selection
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المؤلفون: Matthew P. Dent, Paul L. Carmichael, Francis Martin, Kevin C. Jones
المصدر: Environment International, Vol 83, Iss, Pp 94-106 (2015)
مصطلحات موضوعية: lcsh:GE1-350, Toxicology testing, Male, Physiologically based pharmacokinetic modelling, business.industry, Context (language use), Androgen Antagonists, Environmental Exposure, Pharmacology, Endocrine Disruptors, Animal Testing Alternatives, Risk Assessment, In vitro, Androgen receptor, In vivo, Medicine, Humans, Female, Mode of action, business, Neuroscience, lcsh:Environmental sciences, General Environmental Science, ADME
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المؤلفون: Marguerite M. Vantangoli, Kim Boekelheide, Paul L. Carmichael, Matthew P. Dent, Francis Martin
المصدر: Toxicology Letters. 258:S155
مصطلحات موضوعية: Toxicology testing, endocrine system, 010504 meteorology & atmospheric sciences, medicine.drug_class, General Medicine, Gonadotropin-releasing hormone, 010501 environmental sciences, Pharmacology, Biology, Toxicology, Bioinformatics, 01 natural sciences, Hypothalamic–pituitary–thyroid axis, Hypothalamus, Toxicity, medicine, Endocrine system, Gonadotropin, Receptor, 0105 earth and related environmental sciences
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المؤلفون: Will Davies, Richard Billington, Simon Parry, Stuart Creton, Matthew P. Dent, Gabrielle M. Hawksworth, Kim Z. Travis
المصدر: Regulatory toxicology and pharmacology : RTP. 55(3)
مصطلحات موضوعية: Drug Industry, Agrochemical, business.industry, General Medicine, Toxicology, Animal Welfare, Risk Assessment, Biotechnology, Drug development, Risk analysis (engineering), Animal welfare, Animals, Laboratory, Chemical Industry, New product development, Toxicity Tests, Toxicokinetics, Animals, Pharmacokinetics, business, Risk assessment, Pharmaceutical industry, Blood sampling
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المؤلفون: Gabrielle M. Hawksworth, Matthew P. Dent, Kim Z. Travis, Simon Parry, Richard Billington, Will Davies, Stuart Creton
المصدر: Toxicology. 262:10-11
مصطلحات موضوعية: Reduction (complexity), Toxicology, Risk analysis (engineering), business.industry, Medicine, Risk assessment, business, Animal use
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المؤلفون: Yeyejide Adeleye, Jay Ingram, Rebecca A. Clewell, Michael Davies, Andrew Scott, Qiang Zhang, Sophie Malcomber, Matthew P. Dent, Melvin E. Andersen, Andrew J. P. White, Paul L. Carmichael
المصدر: Toxicology Letters. 211:S130
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Toxicity, medicine, General Medicine, Toxicology, Intensive care medicine, business
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