المؤلفون: Hiromu Egashira, Jun Takeuchi, Masakuni Kurono, Rena Nishizawa, 江頭 啓, 竹内 淳, 西澤 玲奈, 黒野 昌邦

المصدر: MEDCHEM NEWS. 2018, 28(3):127

المؤلفون: Masaharu Komeno, Yuka Takada, Takaki Komiya, Tatsuo Maeda, Haruto Kurata, Ryo Suzuki, Tetsu Kondo, Norikazu Matsunaga, Hiroshi Hagiya, Takeji Ono, Kazuhiro Otsuki, Ken-ici Nunoya, Sachiko Tominaga, Shinji Nakade, Hirotaka Mizuno, Kensuke Kusumi, Hidekazu Kiyoshi, Hiroki Shioya, Masakuni Kurono, Hiromu Habashita

المصدر: Journal of Medicinal Chemistry. 60:9508-9530

مصطلحات موضوعية: 0301 basic medicine, Agonist, chemistry.chemical_classification, biology, Stereochemistry, Chemistry, medicine.drug_class, Sphingosine-1-phosphate receptor, Pharmacology, biology.organism_classification, Amino acid, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Drug Discovery, medicine, Molecular Medicine, Moiety, Cricetulus, Sphingosine-1-phosphate, Receptor, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a93fca9c48ce6fcc55e95a6bf9234011
https://doi.org/10.1021/acs.jmedchem.7b00785

المؤلفون: Haruto, Kurata, Kensuke, Kusumi, Kazuhiro, Otsuki, Ryo, Suzuki, Masakuni, Kurono, Takaki, Komiya, Hiroshi, Hagiya, Hirotaka, Mizuno, Hiroki, Shioya, Takeji, Ono, Yuka, Takada, Tatsuo, Maeda, Norikazu, Matsunaga, Tetsu, Kondo, Sachiko, Tominaga, Ken-Ici, Nunoya, Hidekazu, Kiyoshi, Masaharu, Komeno, Shinji, Nakade, Hiromu, Habashita

المصدر: Journal of medicinal chemistry. 60(23)

مصطلحات موضوعية: Male, Mice, Inbred BALB C, Administration, Oral, CHO Cells, Naphthalenes, Autoimmune Diseases, Rats, Sprague-Dawley, Macaca fascicularis, Mice, Receptors, Lysosphingolipid, Cricetulus, Rats, Inbred Lew, Animals, Azetidines, Humans, Female, Lymphocytes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::39f84e90dba8221686c7c9d410b02f32
https://pubmed.ncbi.nlm.nih.gov/29120624

المؤلفون: Ryo Suzuki, Kazuhiro Otsuki, Takaki Komiya, Masakuni Kurono, Hiromu Habashita, Takeji Ono, Masashi Minami, Hiroshi Hagiya, Shinji Nakade, Kensuke Kusumi, Natsuko Tokuda, Yuka Takada, Hirotaka Mizuno, Hiroki Shioya, Haruto Kurata

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:144-148

مصطلحات موضوعية: Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Naphthalenes, Ligands, Ring (chemistry), Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Sphingosine, In vivo, Drug Discovery, Animals, Humans, Structure–activity relationship, Benzene, Receptor, Molecular Biology, Chemistry, Organic Chemistry, In vitro, Rats, Receptors, Lysosphingolipid, Models, Chemical, Drug Design, Molecular Medicine, Chlorine, Lysophospholipids, Selectivity, Linker

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532f742b01b2135dd127fc5fddbd8f69
https://doi.org/10.1016/j.bmcl.2011.11.048

المؤلفون: Takeji Ono, Kazuhiro Otsuki, Ryo Suzuki, Masakuni Kurono, Takaki Komiya, Hiroki Shioya, Masashi Minami, Hirotaka Mizuno, Yuka Takada, Haruto Kurata, Hiroshi Hagiya, Hiromu Habashita, Shinji Nakade, Kensuke Kusumi

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:3885-3889

مصطلحات موضوعية: Agonist, Propanols, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, CHO Cells, Naphthalenes, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, Cricetulus, Sphingosine, In vivo, Cricetinae, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Lymphocytes, Receptor, Molecular Biology, G protein-coupled receptor, Molecular Structure, Fingolimod Hydrochloride, Chemistry, organic chemicals, Organic Chemistry, In vitro, Receptors, Lysosphingolipid, Propylene Glycols, Molecular Medicine, lipids (amino acids, peptides, and proteins), Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0ea6076a0e05454b8edfc392d3ac65
https://doi.org/10.1016/j.bmcl.2011.05.029

المؤلفون: Masaki Kuse, Hiroshi Ohinata, Akira Takai, Magne O. Sydnes, Masakuni Kurono, Aya Shimomura, Minoru Isobe

المصدر: Bioorganic & Medicinal Chemistry. 16:1747-1755

مصطلحات موضوعية: Molar, Firefly protocol, Natural product, Photochemistry, Organic Chemistry, Clinical Biochemistry, Phosphatase, Pharmaceutical Science, Firefly Luciferin, Inhibitory postsynaptic potential, Biochemistry, chemistry.chemical_compound, chemistry, Molecular Probes, Luminescent Measurements, Drug Discovery, Phosphoprotein Phosphatases, Molecular Medicine, Bioluminescence, Spiro Compounds, Enzyme Inhibitors, Tautomycin, Molecular Biology, Pyrans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a33b6e26c4b24648f2eba21b021161
https://doi.org/10.1016/j.bmc.2007.11.034

المؤلفون: Aya Shimomura, Masakuni Kurono, Minoru Isobe

المصدر: Tetrahedron. 60:1773-1780

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Diazirine, Benzophenone, Moiety, Tautomycin, Binding site, Biochemistry, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::34e48d28fb84eb3fcda6db9150039171
https://doi.org/10.1016/j.tet.2003.12.053

المؤلفون: Minoru Isobe, Masakuni Kurono

المصدر: Tetrahedron. 59:9609-9617

مصطلحات موضوعية: Stereochemistry, Organic Chemistry, Epoxide, Biochemistry, Coupling reaction, Hydrolysate, chemistry.chemical_compound, chemistry, Drug Discovery, Moiety, Degradation (geology), Organic chemistry, Tautomycin, Dithiane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d078660effad4bbdf8306e2bba95045b
https://doi.org/10.1016/j.tet.2003.09.097

المؤلفون: Masakuni Kurono, Akira Hirasawa, Keiji Nishiwaki, Yoshinori Takei, Nobuko Iwamoto, Misato Yasue, Atsushi Sakurai, Takayoshi Kinoshita, Tetsuko Nakaniwa, Katsumi Murata, Shinya Nakamura, Takako Miyazaki, Kazuo Kitaura, Yusuke Sekiguchi, Gozoh Tsujimoto, Isao Nakanishi, Naoya Nagata

المصدر: European journal of medicinal chemistry. 96

مصطلحات موضوعية: Models, Molecular, Stereochemistry, In silico, Drug Evaluation, Preclinical, Crystal structure, Structure-Activity Relationship, Protein kinase CK2, Drug Discovery, Humans, Casein Kinase II, Protein Kinase Inhibitors, Pharmacology, Virtual screening, biology, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Chemistry, Organic Chemistry, General Medicine, Enzyme assay, Solvent, Enzyme Activation, Dipole, biology.protein, Solvents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c645bba2d34c59318021c341b811a87d
https://pubmed.ncbi.nlm.nih.gov/25912672

المؤلفون: Masashi Minami, Haruto Kurata, Masakuni Kurono, Takeji Ono, Kazuhiro Otsuki, Masahiko Terakado, Hirotaka Mizuno, Takuya Seko, Hiroshi Hagiya, Shinji Nakade, Kensuke Kusumi, Hiromu Habashita

المصدر: Bioorganicmedicinal chemistry letters. 21(5)

مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Sphingosine-1-phosphate receptor, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Sphingosine, Drug Discovery, medicine, Moiety, Structure–activity relationship, Animals, Receptor, Molecular Biology, G protein-coupled receptor, Alanine, Chemistry, Fingolimod Hydrochloride, Organic Chemistry, Rats, Receptors, Lysosphingolipid, Cinnamates, Propylene Glycols, beta-Alanine, Molecular Medicine, lipids (amino acids, peptides, and proteins)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb83fd767e708ca4c7567310eb02470
https://pubmed.ncbi.nlm.nih.gov/21295477

المؤلفون: Masakuni Kurono, Minoru Isobe, Akira Takai, Katsunori Tsuboi

المصدر: Chemistry, an Asian journal. 2(3)

مصطلحات موضوعية: Carbon Isotopes, Magnetic Resonance Spectroscopy, Stereochemistry, Organic Chemistry, Phosphatase, General Chemistry, Nuclear magnetic resonance spectroscopy, Biochemistry, chemistry.chemical_compound, chemistry, Isotope Labeling, Phosphoprotein Phosphatases, Moiety, Spiro Compounds, Tautomycin, Protein Phosphatase Inhibitor, Enzyme Inhibitors, Strong binding, Pyrans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f90c6f80635e7adaaa9c94c4762dea
https://pubmed.ncbi.nlm.nih.gov/17441173

المؤلفون: Haruto Kurata, Kensuke Kusumi, Kazuhiro Otsuki, Ryo Suzuki, Masakuni Kurono, Takaki Komiya, Hiroshi Hagiya, Hirotaka Mizuno, Hiroki Shioya, Takeji Ono, Yuka Takada, Tatsuo Maeda, Norikazu Matsunaga, Tetsu Kondo, Sachiko Tominaga, Ken-ici Nunoya, Hidekazu Kiyoshi, Masaharu Komeno, Shinji Nakade, Hiromu Habashita

المصدر: Journal of Medicinal Chemistry; 12/14/2017, Vol. 60 Issue 23, p9508-9530, 23p

المؤلفون: Minoru Isobe, Masakuni Kurono

المصدر: Chemistry Letters. 33:452-453

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Biochemistry, Stereochemistry, Functional group, Phosphatase, polycyclic compounds, Moiety, Dansyl amide, A protein, General Chemistry, Tautomycin, Fluorescence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a580856343a1578a134c16cffeff6732
https://doi.org/10.1246/cl.2004.452

المؤلفون: Hideo Tomioka, Fumika Morisaki, Masakuni Kurono, Katsuyuki Hirai

المصدر: Organic & Biomolecular Chemistry. 3:431

مصطلحات موضوعية: Molecular Structure, Photochemistry, Diradical, Diazomethane, Organic Chemistry, Electron Spin Resonance Spectroscopy, Temperature, Sonogashira coupling, Diazonium Compounds, Thiophenes, Sensitivity and Specificity, Biochemistry, chemistry.chemical_compound, Delocalized electron, Unpaired electron, chemistry, Alkynes, Thiophene, Spectrophotometry, Ultraviolet, Diazo, Singlet state, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd21d0aaf4e8254b474cd96416e01cf2
https://doi.org/10.1039/b409095k