المؤلفون: Malaika D. Argade, Laura DeCristofano, Nirajan Bhattarai, Marvin K. Schulte, Malgorzata Dukat

المصدر: Results in Chemistry, Vol 4, Iss , Pp 100286- (2022)

مصطلحات موضوعية: Galantamine, Lycoramine, SAR, α7 nAChRs, AChE, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715622000054; https://doaj.org/toc/2211-7156

URL الوصول: https://doaj.org/article/a8a0f918e2744feeb7aa9fd23db0b4f7

المؤلفون: Osama I. Alwassil (10885889), Shailesh Khatri (3104355), Marvin K. Schulte (3104364), Sanjay S. Aripaka (10885892), Jens D. Mikkelsen (160806), Małgorzata Dukat (2454808)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Pharmacology, Mental Health, Chemical Sciences not elsewhere classified, aryl 3- position, SAR, compound, N 1, α7 nicotinic ACh receptors, N 1 H, Xenopus laevis oocytes, two-electrode voltage-clamp assay, nature, methyl counterpart 2, novel α7 nAChR antagonist chemotype, α7 Nicotinic Acetylcholine, novel α7 nicotinic ACh, receptor antagonist chemotype, 3- position substituents

Relation: https://figshare.com/articles/journal_contribution/N_sub_1_sub_H-_and_N_sub_1_sub_Substituted_Phenylguanidines_as_7_Nicotinic_Acetylcholine_nACh_Receptor_Antagonists_Structure_Activity_Relationship_Studies/14690942

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00212.s001

المؤلفون: Kavita Sharma, Samjhana Pradhan, Lawrence K. Duffy, Sabina Yeasmin, Nirajan Bhattarai, Marvin K. Schulte

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12987

مصطلحات موضوعية: Alzheimer’s disease, amyloid beta, G-protein-coupled receptors, nicotinic acetylcholine receptors, N-methyl D-aspartate receptors, γ-aminobutyric acid (GABA)

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms222312987

الاتاحة: https://doi.org/10.3390/ijms222312987

المؤلفون: Marvin K Schulte, Shailesh Khatri, Yanzhou Huang, Laura DeCristofano, Gabrielle G. LeBlan

المصدر: Neurotransmitter; Vol 3 (2016): Special Issue Edited by Dr. Hugo R. Arias| Functional and therapeutic aspects of the nicotinic acetylcholine receptor family. ; 2375-2440

وصف الملف: application/pdf

Relation: https://www.smartscitech.com/index.php/NT/article/view/896/879; https://www.smartscitech.com/index.php/NT/article/view/896

الاتاحة: https://www.smartscitech.com/index.php/NT/article/view/896

المؤلفون: Laura DeCristofano, Asha Suryanarayanan, Marvin K. Schulte, Steven Decker

المصدر: Alcohol. 93:35-44

مصطلحات موضوعية: Health (social science), Allosteric modulator, Voltage clamp, Long-term potentiation, General Medicine, Pharmacology, Toxicology, Biochemistry, 030227 psychiatry, 03 medical and health sciences, Behavioral Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Nicotinic agonist, Neurology, chemistry, Desformylflustrabromine, Sedative/hypnotic, Receptor, 030217 neurology & neurosurgery, Acetylcholine receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e186909b8f53068babfde435b40bd40
https://doi.org/10.1016/j.alcohol.2021.02.005

المؤلفون: Osama I. Alwassil, Marvin K. Schulte, Sanjay S Aripaka, Malgorzata Dukat, Jens D. Mikkelsen, Shailesh Khatri

المصدر: ACS Chemical Neuroscience. 12:2194-2201

مصطلحات موضوعية: 0303 health sciences, Physiology, medicine.drug_class, Stereochemistry, Cognitive Neuroscience, Substituent, Antagonist, Cell Biology, General Medicine, Receptor antagonist, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Nicotinic agonist, chemistry, medicine, Structure–activity relationship, Guanidine, 030217 neurology & neurosurgery, Acetylcholine, 030304 developmental biology, Acetylcholine receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe04bcc6a96b6d5445dc8eddf06741ca
https://doi.org/10.1021/acschemneuro.1c00212

المؤلفون: Osama I, Alwassil, Shailesh, Khatri, Marvin K, Schulte, Sanjay S, Aripaka, Jens D, Mikkelsen, Małgorzata, Dukat

المصدر: ACS chemical neuroscience. 12(12)

مصطلحات موضوعية: Structure-Activity Relationship, Xenopus laevis, alpha7 Nicotinic Acetylcholine Receptor, Oocytes, Animals, Humans, Nicotinic Antagonists, Receptors, Nicotinic, Guanidines, Acetylcholine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::308515b8f117153d158a05d292a49686
https://pubmed.ncbi.nlm.nih.gov/34043311

المؤلفون: Laura, DeCristofano, Steven, Decker, Marvin K, Schulte, Asha, Suryanarayanan

المصدر: Alcohol (Fayetteville, N.Y.). 93

مصطلحات موضوعية: Ethanol, Animals, Hypnotics and Sedatives, Receptors, Nicotinic, Hydrocarbons, Brominated, Indole Alkaloids, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::44af13f6463cc8aa778110501b1072ab
https://pubmed.ncbi.nlm.nih.gov/33652092

المؤلفون: Shailesh Khatri, Abel Bult-Ito, Swarup Mitra, Malabika Maulik, Marvin K. Schulte

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4918, p 4918 (2020)

مصطلحات موضوعية: Multiple Sclerosis, Allosteric regulation, Cholinergic Agents, Inflammation, Nerve Tissue Proteins, Review, Receptors, Nicotinic, Catalysis, neuroinflammation, lcsh:Chemistry, Inorganic Chemistry, Therapeutic approach, Allosteric Regulation, Alzheimer Disease, Brain Injuries, Traumatic, medicine, Humans, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Neuroinflammation, Acetylcholine receptor, business.industry, Organic Chemistry, Neurodegenerative Diseases, Parkinson Disease, General Medicine, Computer Science Applications, Nicotinic agonist, lcsh:Biology (General), lcsh:QD1-999, Drug development, Cholinergic, nicotinic acetylcholine receptors, allosteric modulators, medicine.symptom, Inflammation Mediators, business, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d864531d86b486fe30069445aa561e
https://pubmed.ncbi.nlm.nih.gov/32664647

المؤلفون: Michael M. White, Osama I. Alwassil, Marvin K. Schulte, Shailesh Khatri, Ahmed S. Abdelkhalek, Heather L. Nyce, Genevieve S Alley, Malgorzata Dukat, Philip D. Mosier

المصدر: ACS Chemical Neuroscience. 10:1380-1389

مصطلحات موضوعية: Agonist, 0303 health sciences, biology, Physiology, Chemistry, Stereochemistry, medicine.drug_class, Cognitive Neuroscience, Cell Biology, General Medicine, Methylene bridge, Receptor antagonist, Biochemistry, Partial agonist, 5-HT3 receptor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Docking (molecular), biology.protein, medicine, Homology modeling, Receptor, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a1e7746705268d4819974ec7a69cc35
https://doi.org/10.1021/acschemneuro.8b00431

المؤلفون: Shailesh Khatri, Shane Alexander Rideout, Marvin K. Schulte, Michael E. Harris, Clare Stokes, Roger L. Papke, Karsten Hueffer

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Central Nervous System, Xenopus, Neurotoxins, lcsh:Medicine, Biology, Receptors, Nicotinic, medicine.disease_cause, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Protein Domains, Neurotransmitter receptor, medicine, Animals, Humans, Neurotransmitter metabolism, Amino Acid Sequence, Receptor, Caenorhabditis elegans, lcsh:Science, Conserved Sequence, Acetylcholine receptor, Glycoproteins, Multidisciplinary, Behavior, Animal, Sequence Homology, Amino Acid, Virus receptor, Rabies virus, lcsh:R, Virology, 3. Good health, Receptors, Neurotransmitter, 030104 developmental biology, Nicotinic agonist, Host-Pathogen Interactions, lcsh:Q, Peptides, 030217 neurology & neurosurgery, Acetylcholine, medicine.drug, Protein Binding, Snake Venoms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de42b9f64bd25d8eb58152a58a822e23
http://link.springer.com/article/10.1038/s41598-017-12726-4

المؤلفون: D. Ergun, Wisam Toma, Deniz Bagdas, M.I. Damaj, Marvin K. Schulte, Asti Jackson

المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Deney Hayvanları Yetiştirme ve Araştırma Merkezi., Bağdaş, Deniz

المصدر: Eur J Pain

مصطلحات موضوعية: Disease mkodels, animal, Male, 0301 basic medicine, Beta-2, Unclassified drug, Mouse, Receptors, Nicotinic, Pharmacology, Ligands, Neuropathic pain, Nicotinic receptor alpha4beta2, Indole Alkaloids, Antinociception, Nicotine, Nicotinic receptor, Mice, chemistry.chemical_compound, Sensitivity, 0302 clinical medicine, Anesthesiology, Abt-594, Drug activity, Allosterism, Nicotinic Agonists, Priority journal, Desformylflustrabromine, Morphine, Nicotinic agent, Stoichiometry, Hydrocarbons, Brominated, Antiallodynic effect, Megadose, Nicotinic agonist, Indole alkaloid, Clinical neurology, Brominated hydrocarbon, Bromine derivative, Locomotion, medicine.drug, Epibatidine, Nicotinic Receptors, Mecamylamine, Agonist, Allosteric modulator, Efficacy, medicine.drug_class, Drug potentiation, Neurosciences & neurology, Concentration response, Allodynia, Partial agonist, Article, Chronic constriction injury, Low drug dose, Rotarod test, 03 medical and health sciences, Allosteric Regulation, Discriminative-stimulus, medicine, Animals, Animal model, Animal experiment, Cholinergic activity, Animal, Disease model, business.industry, Motor dysfunction, Neurosciences, Nonhuman, Drug effect, Disease Models, Animal, Metabolism, 030104 developmental biology, Anesthesiology and Pain Medicine, nervous system, chemistry, Motor coordination, Neuralgia, Cholinergic, sense organs, business, Controlled study, Neuroscience, 030217 neurology & neurosurgery, NS9283

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6893fa75c309f10eb00917b9c22e563
https://doi.org/10.1002/ejp.1092

المؤلفون: Padmavati Venkataraman, Prasad Joshi, Srinivasan P Venkatachalan, Mani Muthalagi, Harish S Parihar, Karen S Kirschbaum, Marvin K Schulte

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/3e/b9/BMC_Biochem_2002_Jun_13_3_16.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.741

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.741

المؤلفون: Padmavati Venkataraman, Srinivasan P Venkatachalan, Prasad R Joshi, Mani Muthalagi, Marvin K Schulte

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/41/54/BMC_Biochem_2002_Jun_13_3_15.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.1494

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.1494

المؤلفون: Michael M. White, Heather L. Nyce, Katie Alix, Marvin K. Schulte, Malgorzata Dukat, Samantha Casterlow, Shailesh Khatri, Philip D. Mosier, Dong Yan

المصدر: ACS Chemical Neuroscience. 7:1565-1574

مصطلحات موضوعية: 0301 basic medicine, Agonist, Physiology, medicine.drug_class, Chemistry, Stereochemistry, Cognitive Neuroscience, Protein subunit, Mutagenesis, Antagonist, Cell Biology, General Medicine, Biochemistry, Partial agonist, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, medicine, Receptor, Guanidine, Site-directed mutagenesis, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::18d73945b1a8ffbc3798d0f736db6730
https://doi.org/10.1021/acschemneuro.6b00196

المؤلفون: Ahmed S, Abdelkhalek, Genevieve S, Alley, Osama I, Alwassil, Shailesh, Khatri, Philip D, Mosier, Heather L, Nyce, Michael M, White, Marvin K, Schulte, Małgorzata, Dukat

المصدر: ACS chemical neuroscience. 10(3)

مصطلحات موضوعية: HEK293 Cells, Dose-Response Relationship, Drug, Xenopus, Animals, Humans, Serotonin 5-HT3 Receptor Antagonists, Female, Receptors, Serotonin, 5-HT3, Guanidines, Methane, Protein Structure, Secondary, Protein Binding, Protein Structure, Tertiary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::49b6c8f5ccb4fbedf7ee2da0baf7a689
https://pubmed.ncbi.nlm.nih.gov/30375852

المؤلفون: Rossana Ferrara-Pontoriero, Marvin K. Schulte, Richard A. Glennon, Yilong Ma, Malgorzata Dukat, Yanzhou Huang, Atul D. Jain, Nadezhda German

المصدر: ACS chemical neuroscience. 9(12)

مصطلحات موضوعية: Allosteric modulator, Patch-Clamp Techniques, Physiology, Cognitive Neuroscience, Xenopus, Pharmacology, Cholinergic Agonists, Receptors, Nicotinic, 010402 general chemistry, 01 natural sciences, Biochemistry, Indole Alkaloids, Structure-Activity Relationship, Xenopus laevis, Allosteric Regulation, medicine, Animals, Acetylcholine receptor, Indole alkaloid, biology, 010405 organic chemistry, Chemistry, Cell Biology, General Medicine, biology.organism_classification, Acetylcholine, 0104 chemical sciences, Hydrocarbons, Brominated, Electrophysiology, Nicotinic agonist, Oocytes, Pharmacophore, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb25213cc428d6d3734bcd47decc925
https://pubmed.ncbi.nlm.nih.gov/30028943

المؤلفون: Marvin K. Schulte, Xiaolei Pan, Douglas H. Sweet, Jose M. Eltit, Ernesto Solis, Louis J. De Felice, Kavita A. Iyer, Katie Alix, Malgorzata Dukat, Shailesh Khatri, Malaika D. Argade

المصدر: Psychopharmacology. 236(7)

مصطلحات موضوعية: Male, medicine.drug_class, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Mice, Xenopus laevis, 0302 clinical medicine, Quinazoline, medicine, Serotonin receptor antagonist, Animals, Humans, Receptor, Mice, Inbred ICR, Dose-Response Relationship, Drug, Chemistry, Depression, Receptor antagonist, Tail suspension test, Antidepressive Agents, 030227 psychiatry, HEK293 Cells, Mechanism of action, Hindlimb Suspension, Quinazolines, Antidepressant, Drug Therapy, Combination, Female, Serotonin Antagonists, medicine.symptom, Reuptake inhibitor, 030217 neurology & neurosurgery, Locomotion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fadfe7909b48e38ec77bf37dc33fddc
https://pubmed.ncbi.nlm.nih.gov/30805668

المؤلفون: Richard Glenon, Marvin K. Schulte, McKenzie Mucha, Abel Bult-Ito, Shailesh Khatri, Swarup Mitra

المصدر: Frontiers in Behavioral Neuroscience

مصطلحات موضوعية: 0301 basic medicine, Allosteric modulator, Cognitive Neuroscience, Allosteric regulation, Pharmacology, Marble burying, 03 medical and health sciences, chemistry.chemical_compound, Behavioral Neuroscience, 0302 clinical medicine, obsessive compulsive disorder, α4β2 nicotinic receptors, medicine, non-induced compulsive-like mice, Receptor, Original Research, Acetylcholine receptor, desformylflustrabromine (dFBr), 3. Good health, 030104 developmental biology, Nicotinic agonist, Neuropsychology and Physiological Psychology, chemistry, Desformylflustrabromine, positive allosteric modulator, Neuroscience, 030217 neurology & neurosurgery, Acetylcholine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0602ab329ccf3ed03aceab2b43da526c

المؤلفون: Katie, Alix, Shailesh, Khatri, Philip D, Mosier, Samantha, Casterlow, Dong, Yan, Heather L, Nyce, Michael M, White, Marvin K, Schulte, Małgorzata, Dukat

المصدر: ACS chemical neuroscience. 7(11)

مصطلحات موضوعية: Models, Molecular, Dose-Response Relationship, Drug, Molecular Structure, Xenopus, Serotonin 5-HT3 Receptor Agonists, Guanidines, Membrane Potentials, Mice, HEK293 Cells, Cell Line, Tumor, Mutation, Oocytes, Animals, Humans, Serotonin 5-HT3 Receptor Antagonists, Receptors, Serotonin, 5-HT3, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::28fc769012d16a00c4c918c738b7b36f
https://pubmed.ncbi.nlm.nih.gov/27533595