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المؤلفون: Martina Brigitte Duschmalé, Camilla Ceroni, Hendrik Knoetgen, Sylke Hoehnel, Roberto Villaseñor, Nathalie Brandenberg, Alina Gavrilov, Jens Niewoehner, Evodie Lassalle, Claire Simonneau, Elena Kassianidou
المصدر: Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-17 (2021)
Fluids and Barriers of the CNSمصطلحات موضوعية: Transferrin receptor, Bioengineering, Blood–brain barrier, Endocytosis, Receptor-mediated transcytosis, Antibodies, Cellular and Molecular Neuroscience, High-throughput in vitro model, Developmental Neuroscience, Caveolae, Caveolin, Receptors, Transferrin, Organoid, medicine, Animals, Humans, RC346-429, Cells, Cultured, Chemistry, Research, Endothelial Cells, General Medicine, Receptor-mediated endocytosis, Coculture Techniques, Cell biology, Organoids, medicine.anatomical_structure, Neurology, Transcytosis, Blood-Brain Barrier, Astrocytes, Neurology. Diseases of the nervous system, Pericytes
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المؤلفون: Filippo Sladojevich, Remo Gamboni, Tanja Minz, Philippe Ringler, Rainer Alex, Sabine Kux van Geijtenbeek, Michaela Portmann, Axel Ducret, Matthias E. Lauer, Ravi Jagasia, Eric-André Kusznir, Bettina Nordbo, Sabine Sewing, Michael Keller, Nikhil J. Pandya, Erich Koller, Philip Grossen, Marco Berrera, Martina Brigitte Duschmalé, Sylwia Huber, Marianne Lerbech Jensen
المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 158:198-210
مصطلحات موضوعية: Pluripotent Stem Cells, Drug Compounding, media_common.quotation_subject, Primary Cell Culture, Drug Evaluation, Preclinical, Oligonucleotides, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, Extracellular Vesicles, Mice, 03 medical and health sciences, 0302 clinical medicine, Lipidomics, Animals, Humans, Tissue Distribution, Locked nucleic acid, Internalization, media_common, Neurons, Drug Carriers, Gene knockdown, Chemistry, General Medicine, Oligonucleotides, Antisense, 021001 nanoscience & nanotechnology, In vitro, Microvesicles, Cell biology, Milk, Drug delivery, Nucleic acid, 0210 nano-technology, Biotechnology
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المؤلفون: Martina Brigitte Duschmalé, Erich Koller, Andreas Brink, Claudia Senn, Guy Fischer, Christophe Husser, Martin R. Edelmann
المصدر: AAPS Open, Vol 7, Iss 1, Pp 1-17 (2021)
مصطلحات موضوعية: Radioactive Label, MALAT1, Oligonucleotide, Chemistry, RNA, Malat1, RM1-950, General Medicine, Tritium, In vitro, RS1-441, Pharmacy and materia medica, Biochemistry, Pharmacokinetics, In vivo, Antisense oligonucleotide, Specific activity, Therapeutics. Pharmacology, Radiolabeling
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المؤلفون: Roberto Villaseñor, Nathalie Brandenberg, Sylke Hoehnel, Camilla Ceroni, Claire Simonneau, Martina Brigitte Duschmalé, Alina Gavrilov, Hendrik Knoetgen, Evodie Lassalle, Jens Niewoehner
مصطلحات موضوعية: biology, Chemistry, Transferrin receptor, Receptor-mediated endocytosis, Blood–brain barrier, Endocytosis, Clathrin, Cell biology, medicine.anatomical_structure, Transcytosis, Caveolin, medicine, Organoid, biology.protein
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المؤلفون: Martina Brigitte Duschmalé, Marianne R. Møller, Konrad Bleicher, Jesper Wengel, Nanna Albæk, Henrik Frydenlund Hansen, Jörg Duschmalé, Erich Koller, Klaus Jensen, Troels Koch
المصدر: Nucleic Acids Research
Duschmalé, J, Hansen, H F, Duschmalé, M, Koller, E, Albaek, N, Møller, M R, Jensen, K, Koch, T, Wengel, J & Bleicher, K 2020, ' In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3' and 5' thiophosphate linkages ', Nucleic acids research, vol. 48, no. 1, pp. 63-74 . https://doi.org/10.1093/nar/gkz1099مصطلحات موضوعية: RNA Stability, Ribonuclease H, Oligonucleotides, Phosphorothioate Oligonucleotides, Stereoisomerism, Biology, Kidney, 01 natural sciences, Thiophosphate, Phosphates, 03 medical and health sciences, chemistry.chemical_compound, Mice, Chemical Biology and Nucleic Acid Chemistry, In vivo, Cell Line, Tumor, Genetics, Animals, Humans, RNase H, Lung, 030304 developmental biology, 0303 health sciences, Nuclease, 010405 organic chemistry, Oligonucleotide, Kidney metabolism, 0104 chemical sciences, Mice, Inbred C57BL, Biochemistry, chemistry, Liver, Apolipoprotein B-100, biology.protein, Female, RNA, Long Noncoding
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