المؤلفون: Houda Zentar, Fatin Jannus, Marta Medina-O’Donnell, Az-eddine El Mansouri, Antonio Fernández, José Justicia, Enrique Alvarez-Manzaneda, Fernando J. Reyes-Zurita, Rachid Chahboun

المصدر: Molecules, Vol 28, Iss 17, p 6208 (2023)

مصطلحات موضوعية: function-oriented synthesis (FOS), cassane diterpenoids, anticancer, anti-inflammatory, docking, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/17/6208; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/c948a183fadb45788d80e3bc367ad5cf

المؤلفون: Houda Zentar, Fatin Jannus, Marta Medina-O’Donnell, José A. Lupiáñez, José Justicia, Ramón Alvarez-Manzaneda, Fernando J. Reyes-Zurita, Enrique Alvarez-Manzaneda, Rachid Chahboun

المصدر: Molecules, Vol 27, Iss 17, p 5705 (2022)

مصطلحات موضوعية: natural products, semisynthesis, cassane diterpenoids, anti-inflammatory activity, anti-cancer activity, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/17/5705; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/ecebf23647de40cd91d6145d6ccafff0

المؤلفون: Fatin Jannus, Marta Medina-O’Donnell, Francisco Rivas, Luis Díaz-Ruiz, Eva E. Rufino-Palomares, José A. Lupiáñez, Andrés Parra, Fernando J. Reyes-Zurita

المصدر: Biomolecules, Vol 10, Iss 10, p 1375 (2020)

مصطلحات موضوعية: triterpenes, oleanolic acid, (PEG)ylated oleanolic acid, extrinsic apoptotic pathway, anti-tumor mechanisms, hepatocellular carcinoma, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/10/10/1375; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/0ed901ac2f9b4dd2a1cac61c03bac6a3

المؤلفون: Aixa Aguilera-Garrido, Pablo Graván, Saúl A. Navarro-Marchal, Marta Medina-O’Donnell, Andrés Parra, María José Gálvez-Ruiz, Juan Antonio Marchal, Francisco Galisteo-González

المصدر: Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114828- (2023)

مصطلحات موضوعية: Maslinic acid, Curcumin, Solid lipid nanoparticles, Poloxamer, Pancreatic cancer, Breast cancer, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332223006182; https://doaj.org/toc/0753-3322; https://doaj.org/article/9f25c8bf1c8d4f0692345791e49d69e9

الاتاحة: https://doi.org/10.1016/j.biopha.2023.114828
https://doaj.org/article/9f25c8bf1c8d4f0692345791e49d69e9

المؤلفون: Fatin Jannus (10839141), Marta Medina-O’Donnell (1768408), Francisco Rivas (1768414), Luis Díaz-Ruiz (10844616), Eva E. Rufino-Palomares (844704), José A. Lupiáñez (10844619), Andrés Parra (844708), Fernando J. Reyes-Zurita (7500863)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Cancer, apopotosis, Biochemical analyses, Organic products

Relation: https://figshare.com/articles/journal_contribution/A_Diamine-PEGylated_Oleanolic_Acid_Derivative_Induced_Efficient_Apoptosis_through_a_Death_Receptor_and_Mitochondrial_Apoptotic_Pathway_in_HepG2_Human_Hepatoma_Cells/14639148

الاتاحة: https://doi.org/10.6084/m9.figshare.14639148.v1

المؤلفون: Antonio A García-Valdivia (10927586), Amalia García-García (10927438), Fatin Jannus (10839141), Andoni Zabala-Lekuona (10927589), José M Méndez-Arriaga (10927591), Belén Fernández (2867825), Marta Medina-O'donnell (10927594), Gloria B Ramírez-Rodríguez (10927598), José M Delgado-López (10927601), Luisa M Pastrana-Martínez (10927606), Javier Cepeda (1605727), José A Lupiáñez (10927607), Fernando J Reyes-Zurita (10927610), Antonio Rodríguez-Diéguez (2498050)

مصطلحات موضوعية: Biochemistry, Cell Biology, Parasitology, Inorganic Chemistry, antiparasitic agent, antiinflammatory effect

Relation: https://figshare.com/articles/journal_contribution/Antiparasitic_anti-inflammatory_and_cytotoxic_activities_of_2D_coordination_polymers_based_on_1H-indazole-5-carboxylic_acid/14737986

الاتاحة: https://doi.org/10.6084/m9.figshare.14737986.v1

المؤلفون: Karina Vega-Granados (6984491), Marta Medina-O’Donnell (1768408), Francisco Rivas (1768414), Fernando J. Reyes-Zurita (7500863), Antonio Martinez (111896), Luis Alvarez de Cienfuegos (8309037), Jose A. Lupiañez (1768417), Andres Parra (1768411)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Hematology, Plant Biology, Chemical Sciences not elsewhere classified, 16-F, maslinic acid, IEC, C -3 hydroxy groups, cytotoxic results, WRL, C -2, coumarin -3-carboxylic acid, triterpene acid, apoptosis rates, cell-cycle arrest, nontumor cell lines, triterpene skeleton, submicromolar IC 50 values, apoptotic effects, HT, cell viability, cancer cell lines, Biological Activity, cytotoxic effects

Relation: https://figshare.com/articles/journal_contribution/Synthesis_and_Biological_Activity_of_Triterpene_Coumarin_Conjugates/14551111

الاتاحة: https://doi.org/10.1021/acs.jnatprod.1c00128.s001

المؤلفون: Fatin Jannus, Marta Medina-O’Donnell, Veronika E. Neubrand, Milagros Marín, Maria J. Saez-Lara, M. Rosario Sepulveda, Eva E. Rufino-Palomares, Antonio Martinez, Jose A. Lupiañez, Andres Parra, Francisco Rivas, Fernando J. Reyes-Zurita

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8158

مصطلحات موضوعية: oleanolic acid, triterpenes derivatives, diamine-(PEG)ylated oleanolic acid, OADP, anti-inflammatory mechanism, RAW 264.7 cell line, TPA-induced acute ear edema

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biophysics; https://dx.doi.org/10.3390/ijms22158158

الاتاحة: https://doi.org/10.3390/ijms22158158

المؤلفون: Marta Medina-O’Donnell, Karina Vega-Granados, Antonio Martinez, M. Rosario Sepúlveda, José Antonio Molina-Bolívar, Luis Álvarez de Cienfuegos, Andres Parra, Fernando J. Reyes-Zurita, Francisco Rivas

المصدر: Journal of natural products.

مصطلحات موضوعية: Pharmacology, Complementary and alternative medicine, Anti-cancer, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Triterpene, Fluorescent Probes, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ad0b850900dc2ead8433f38422188d
https://pubmed.ncbi.nlm.nih.gov/36542806

المؤلفون: Houda Zentar, Fatin Jannus, Pilar Gutierrez, Marta Medina-O’Donnell, José Antonio Lupiáñez, Fernando J. Reyes-Zurita, Enrique Alvarez-Manzaneda, Rachid Chahboun

المصدر: Journal of natural products. 85(10)

مصطلحات موضوعية: Pharmacology, Lipopolysaccharides, Membrane Potential, Mitochondrial, Organic Chemistry, Anti-Inflammatory Agents, Pharmaceutical Science, Apoptosis, Antineoplastic Agents, Analytical Chemistry, Complementary and alternative medicine, Cell Line, Tumor, Drug Discovery, Molecular Medicine, Diterpenes, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a3ac22f6323e6881d04b5a159baf00
https://pubmed.ncbi.nlm.nih.gov/36215157

المؤلفون: Houda Zentar, Fatin Jannus, Marta Medina-O’Donnell, José A. Lupiáñez, José Justicia, Ramón Alvarez-Manzaneda, Fernando J. Reyes-Zurita, Enrique Alvarez-Manzaneda, Rachid Chahboun

المصدر: Molecules; Volume 27; Issue 17; Pages: 5705
riUAL. Repositorio Institucional de la Universidad de Almería
Universidad de Almería

مصطلحات موضوعية: Caesalpinia, Molecular Structure, natural products, Organic Chemistry, Anti-Inflammatory Agents, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Polyenes, Nitric Oxide, Analytical Chemistry, cassane diterpenoids, Chemistry (miscellaneous), Cell Line, Tumor, Drug Discovery, anti-cancer activity, Molecular Medicine, semisynthesis, Humans, anti-inflammatory activity, Physical and Theoretical Chemistry, Diterpenes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e0debd8f39e09894526a49ecccee0d
https://hdl.handle.net/10481/77050

المؤلفون: Karina Vega-Granados, Fernando J. Reyes-Zurita, Antonio Martínez, Andrés Parra, José A. Lupiáñez, Luis Álvarez de Cienfuegos, Marta Medina-O'Donnell, Francisco Rivas

المصدر: Journal of Natural Products

مصطلحات موضوعية: Carboxylic acid, Melanoma, Experimental, Pharmaceutical Science, Antineoplastic Agents, 01 natural sciences, Article, Analytical Chemistry, chemistry.chemical_compound, Mice, Triterpene, Maslinic acid, Coumarins, Drug Discovery, Animals, Humans, heterocyclic compounds, Viability assay, Olive Oil, Pharmacology, chemistry.chemical_classification, Membrane Potential, Mitochondrial, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Biological activity, Cell Cycle Checkpoints, Hep G2 Cells, Triterpenes, 0104 chemical sciences, Hep G2, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Biochemistry, chemistry, Cell culture, Molecular Medicine, HT29 Cells, Conjugate

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac48440b28dd36bca827599f5e389c1
http://europepmc.org/articles/PMC8476055

المؤلفون: Aixa Aguilera-Garrido, Pablo Graván, Saúl A. Navarro-Marchal, Marta Medina-O’Donnell, Andrés Parra, María José Gálvez-Ruiz, Juan Antonio Marchal, Francisco Galisteo-González

مصطلحات موضوعية: Pharmacology, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb544e0ccafb6f21772e30c1ef831ef5
https://doi.org/10.21203/rs.3.rs-1719288/v1

المؤلفون: Antonio Martínez, Mario Cano-Muñoz, Andrés Parra, Marta Medina-O'Donnell, Fernando J. Reyes-Zurita, José A. Lupiáñez, Fatima Rivas

المصدر: Journal of Natural Products. 82:2886-2896

مصطلحات موضوعية: medicine.medical_treatment, Pharmaceutical Science, 01 natural sciences, Analytical Chemistry, Structure-Activity Relationship, chemistry.chemical_compound, HIV-1 protease, Drug Discovery, medicine, Structure–activity relationship, Oleanolic Acid, IC50, Oleanolic acid, Pharmacology, chemistry.chemical_classification, Protease, biology, 010405 organic chemistry, Organic Chemistry, HIV Protease Inhibitors, 0104 chemical sciences, Amino acid, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, chemistry, Biochemistry, Docking (molecular), HIV-1, biology.protein, Molecular Medicine, Acyl group

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b954400897fc6dc39f20abf4e1c0bf
https://doi.org/10.1021/acs.jnatprod.9b00649

المؤلفون: Andrés Parra, Marta Medina-O'Donnell, J.A. Molina-Bolívar, Francisco Galisteo-González, Alberto Martinez, C. Carnero Ruiz

المصدر: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 214:161-169

مصطلحات موضوعية: Circular dichroism, Hot Temperature, Serum Albumin, Human, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Protein Structure, Secondary, Fluorescence spectroscopy, Analytical Chemistry, Protein structure, Coumarins, Fluorescence Resonance Energy Transfer, medicine, Humans, Instrumentation, Protein secondary structure, Spectroscopy, Chemistry, Circular Dichroism, Tryptophan, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Human serum albumin, Fluorescence, Atomic and Molecular Physics, and Optics, 0104 chemical sciences, Spectrometry, Fluorescence, Förster resonance energy transfer, Biophysics, 0210 nano-technology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da19d7d4640c69cd83284b3acd9e8b9
https://doi.org/10.1016/j.saa.2019.02.014

المؤلفون: Antonio Martínez, Eva E. Rufino-Palomares, Veronika E Neubrand, María José Sáez-Lara, M. Rosario Sepúlveda, Fatin Jannus, Francisco Rivas, Marta Medina-O'Donnell, Fernando J. Reyes-Zurita, José A. Lupiáñez, Andrés Parra, Milagros Marín

المصدر: International Journal of Molecular Sciences
Digibug. Repositorio Institucional de la Universidad de Granada
instname
International Journal of Molecular Sciences, Vol 22, Iss 8158, p 8158 (2021)
Volume 22
Issue 15

مصطلحات موضوعية: 0301 basic medicine, Male, TPA‐induced acute ear edema, Lipopolysaccharide, Anti-Inflammatory Agents, Pharmacology, chemistry.chemical_compound, Mice, TPA-induced acute ear edema, 0302 clinical medicine, Anti‐inflammatory mechanism, Edema, Triterpenes derivatives, Biology (General), Oleanolic acid, Spectroscopy, General Medicine, Computer Science Applications, Chemistry, 030220 oncology & carcinogenesis, triterpenes derivatives, diamine-(PEG)ylated oleanolic acid, medicine.symptom, QH301-705.5, medicine.drug_class, Diamine‐(PEG)ylated oleanolic acid, Inflammation, Catalysis, Anti-inflammatory, Article, Nitric oxide, Inorganic Chemistry, 03 medical and health sciences, OADP, oleanolic acid, In vivo, medicine, Animals, Physical and Theoretical Chemistry, Ear Diseases, QD1-999, Molecular Biology, Organic Chemistry, RAW 264.7 cell line, In vitro, Mice, Inbred C57BL, 030104 developmental biology, RAW 264.7 Cells, chemistry, Phorbol, anti-inflammatory mechanism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af6686bb2b7d275a1cadf8a0db31204
https://pubmed.ncbi.nlm.nih.gov/34360922

المؤلفون: Francisco Rivas, Fatin Jannus, Andrés Parra, Marta Medina-O'Donnell, Fernando J. Reyes-Zurita, Eva E. Rufino-Palomares, José A. Lupiáñez, Luis Díaz-Ruiz

المصدر: Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Biomolecules, Vol 10, Iss 1375, p 1375 (2020)
Biomolecules
Volume 10
Issue 10
Digibug. Repositorio Institucional de la Universidad de Granada
instname

مصطلحات موضوعية: 0301 basic medicine, Cell cycle checkpoint, Hepatocellular carcinoma, lcsh:QR1-502, Apoptosis, Biochemistry, lcsh:Microbiology, Polyethylene Glycols, chemistry.chemical_compound, 0302 clinical medicine, Oleanolic acid, Anthracenes, Membrane Potential, Mitochondrial, Caspase 3, Kinase, Liver Neoplasms, Hep G2 Cells, Receptors, Death Domain, hepatocellular carcinoma, Mitochondria, Up-Regulation, anti-tumor mechanisms, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Carcinoma, Hepatocellular, Down-Regulation, Diamines, Article, 03 medical and health sciences, oleanolic acid, Downregulation and upregulation, triterpenes, Humans, Extrinsic apoptotic pathway, Molecular Biology, extrinsic apoptotic pathway, Cell growth, JNK Mitogen-Activated Protein Kinases, Anti-tumor mechanisms, HCCS, G1 Phase Cell Cycle Checkpoints, digestive system diseases, Triterpenes, (PEG)ylated oleanolic acid, 030104 developmental biology, chemistry, Cell culture, Cancer research, Tumor Suppressor Protein p53

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7eb4bd1398d3bbef86552261f501119

المؤلفون: José Manuel Delgado-López, Amalia García-García, Antonio Rodríguez-Diéguez, Fatin Jannus, Luisa M. Pastrana-Martínez, Marta Medina-O'Donnell, José M. Méndez-Arriaga, Gloria Belén Ramírez-Rodríguez, Belén Fernández, Fernando J. Reyes-Zurita, Javier Cepeda, José A. Lupiáñez, Antonio A. García-Valdivia, Andoni Zabala-Lekuona

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Antiparasitic, Indazoles, medicine.drug_class, Carboxylic acid, Anti-Inflammatory Agents, Antiprotozoal Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, Anticancer activity, Nitric oxide, Inorganic Chemistry, Mice, chemistry.chemical_compound, Coordination Complexes, medicine, Vanillic acid, Animals, Leishmania, chemistry.chemical_classification, Indazole, Cytotoxins, 010405 organic chemistry, Ligand, Polymer, Combinatorial chemistry, 0104 chemical sciences, 1H-indazole-5-carboxylic acid, Coordination polymers, RAW 264.7 Cells, chemistry, Photocatalysis, Anti-inflammatory

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f82e4289dfc3eb1deec6fae61f6b928

المؤلفون: Fatin Jannus, Belén Fernández, José Ángel García, Antonio Rodríguez-Diéguez, Javier Cepeda, Fernando J. Reyes-Zurita, Duane Choquesillo-Lazarte, Itziar Oyarzabal, José A. Lupiáñez, Marta Medina-O'Donnell, Santiago Gómez-Ruiz, Jerónimo Parra, Antonio A. García-Valdivia

المساهمون: Universidad del País Vasco, Junta de Andalucía, Ministerio de Economía y Competitividad (España), Choquesillo-Lazarte, Duane, Choquesillo-Lazarte, Duane [0000-0002-7077-8972]

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Lanthanide, Models, Molecular, Luminescence, Polymers, Carboxylic Acids, chemistry.chemical_element, Aminopyridines, Antineoplastic Agents, 010402 general chemistry, Crystallography, X-Ray, Ligands, 01 natural sciences, Biochemistry, Lanthanoid Series Elements, Luminescence properties, Anticancer activity, Inorganic Chemistry, Magnetization, Magnetics, Mice, Transition metal, Coordination Complexes, Lanthanides, Animals, Humans, Metal-Organic Frameworks, Cell Proliferation, 010405 organic chemistry, Ligand, Relaxation (NMR), Cobalt, Hep G2 Cells, Transition metals, 0104 chemical sciences, Coordination polymers, Crystallography, Single-Molecule Magnets, chemistry, Dysprosium, HT29 Cells, Copper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09eeb915383af4331bd4dd7d07e103a
http://hdl.handle.net/10261/235411

المؤلفون: Francisco Rivas, Marta Medina-O'Donnell, Fernando J. Reyes-Zurita, Antonio Martínez, José A. Lupiáñez, Andrés Parra

المصدر: European Journal of Medicinal Chemistry. 148:325-336

مصطلحات موضوعية: Cell Survival, Antineoplastic Agents, Apoptosis, Diamines, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Triterpene, Maslinic acid, Cell Line, Tumor, Amide, Diamine, Drug Discovery, Humans, Viability assay, Oleanolic Acid, Cytotoxicity, Oleanolic acid, Membrane Potential, Mitochondrial, Pharmacology, chemistry.chemical_classification, 010405 organic chemistry, Organic Chemistry, Cell Cycle Checkpoints, General Medicine, Triterpenes, 0104 chemical sciences, Hep G2, chemistry, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0984de560acdd63c694ae61125d04d57
https://doi.org/10.1016/j.ejmech.2018.02.044