المؤلفون: Diana G. Wang, Marcia N. Paddock, Mark R. Lundquist, Janet Y. Sun, Oksana Mashadova, Solomon Amadiume, Timothy W. Bumpus, Cindy Hodakoski, Benjamin D. Hopkins, Matthew Fine, Amanda Hill, T. Jonathan Yang, Jeremy M. Baskin, Lukas E. Dow, Lewis C. Cantley

المصدر: Cell Reports, Vol 27, Iss 7, Pp 1991-2001.e5 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719305431; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/71a90e95ad2b4f258e22b9cc1e10ee98

المؤلفون: Mark R. Lundquist, Samie R. Jaffrey

المصدر: Genes, Vol 14, Iss 12, p 2231 (2023)

مصطلحات موضوعية: MICAL2, MRTF-A, serum response factor, Gas6, Axl, Genetics, QH426-470

Relation: https://www.mdpi.com/2073-4425/14/12/2231; https://doaj.org/toc/2073-4425; https://doaj.org/article/a6882479ec6840b894001b74b04c8029

الاتاحة: https://doi.org/10.3390/genes14122231
https://doaj.org/article/a6882479ec6840b894001b74b04c8029

المؤلفون: Sirano Dhe-Paganon, Theresa D. Manz, Lewis C. Cantley, Scott B. Ficarro, Hyuk-Soo Seo, Marcia N. Paddock, Mingfeng Hao, Nathanael S. Gray, Tinghu Zhang, Baishan Jiang, Hyeseok Shim, Jarrod A. Marto, Nicholas Kwiatkowski, Diana G. Wang, Christopher M. Browne, James M. Cunningham, T. Jonathan Yang, Sindhu Carmen Sivakumaren, Mark R. Lundquist, Fleur M. Ferguson, Pranav Krishnan

مصطلحات موضوعية: Autophagosome, 0303 health sciences, Kinase, Drug discovery, Chemistry, Autophagy, Cancer, medicine.disease, 3. Good health, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, 030220 oncology & carcinogenesis, medicine, TFEB, Kinome, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc1b0cef434a17aa0f69572842f5ff5

المؤلفون: Nathanael S. Gray, Lewis C. Cantley, Christopher M. Browne, Theresa D. Manz, Jarrod A. Marto, Hyeseok Shim, Pranav Krishnan, Diana G. Wang, Scott B. Ficarro, Nicholas Kwiatkowski, James M. Cunningham, Mark R. Lundquist, Fleur M. Ferguson, Hyuk-Soo Seo, Mingfeng Hao, Marcia N. Paddock, T. Jonathan Yang, Sindhu Carmen Sivakumaren, Baishan Jiang, Sirano Dhe-Paganon, Tinghu Zhang

المصدر: Cell Chem Biol

مصطلحات موضوعية: Autophagosome, Clinical Biochemistry, Biology, Biochemistry, Article, Downregulation and upregulation, Catalytic Domain, Cell Line, Tumor, Drug Discovery, medicine, Humans, Kinome, Molecular Targeted Therapy, Protein Kinase Inhibitors, Molecular Biology, Pharmacology, Drug discovery, Kinase, Autophagy, Cancer, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Molecular Docking Simulation, Leukemia, Myeloid, Acute, Phosphotransferases (Alcohol Group Acceptor), Cancer research, Molecular Medicine, TFEB

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c61db14f9907d78cc5960d931fcf67
https://doi.org/10.1016/j.chembiol.2020.02.003

المؤلفون: Lewis C. Cantley, Mark R. Lundquist, Lukas E. Dow, Marcia N. Paddock, Oksana Mashadova, Janet Sun, Timothy W. Bumpus, T. Jonathan Yang, Benjamin D. Hopkins, Matthew Fine, Diana G. Wang, Jeremy M. Baskin, Solomon C. Amadiume, Cindy Hodakoski, Amanda Hill

المصدر: Cell reports
Cell Reports, Vol 27, Iss 7, Pp 1991-2001.e5 (2019)

مصطلحات موضوعية: 0301 basic medicine, Phosphatidylinositol 4,5-Diphosphate, medicine.medical_treatment, Allosteric regulation, Mutant, Stimulation, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, medicine, Pi, Animals, Humans, Insulin, lcsh:QH301-705.5, PI3K/AKT/mTOR pathway, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Wild type, In vitro, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Insulin receptor, 030104 developmental biology, Enzyme, lcsh:Biology (General), chemistry, biology.protein, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45e56d5282b2dcf9b6e7647222a7fa9
https://doi.org/10.1101/370544

المؤلفون: Solomon C. Amadiume, Marcus D. Goncalves, Xiang Li, Himisha Beltran, Rohan Bareja, Chantal Pauli, Andrea Sboner, Diana G. Wang, Mark A. Rubin, Siddhartha Mukherjee, David Wu, Cindy Hodakoski, Mark R. Lundquist, Xing Du, Emily M. Harris, Yan Ma, Benjamin D. Hopkins, Lewis C. Cantley

المصدر: Nature. 560(7719)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, Cell Survival, medicine.medical_treatment, Glucose uptake, Adipose tissue, Mice, Nude, Pharmacology, P110α, Carbohydrate metabolism, 03 medical and health sciences, Mice, Insulin resistance, Neoplasms, Medicine, Animals, Insulin, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Feedback, Physiological, Multidisciplinary, business.industry, Kinase, TOR Serine-Threonine Kinases, medicine.disease, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fe621962c16ab187c8685652318d53
https://pubmed.ncbi.nlm.nih.gov/30158705

المؤلفون: Yan Ma, Marcus D. Goncalves, Benjamin D. Hopkins, Xing Du, Lewis C. Cantley, Solomon C. Amadiume, Diana G. Wang, Mark R. Lundquist, Emily M. Harris, Chantal Pauli, Himisha Beltran, Mark A. Rubin, Siddhartha Mukherjee, David Wu, Rohan Bareja, Andrea Sboner, Xiang Li, Cindy Hodakoski

المصدر: Nature

مصطلحات موضوعية: Multidisciplinary, business.industry, Insulin, medicine.medical_treatment, Bioinformatics, Article, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Text mining, medicine, business, 030217 neurology & neurosurgery, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139ddeef04934430981187e17aeab323
https://doi.org/10.1038/s41586-018-0506-3

المؤلفون: Thomas B.K. Watkins, Marcin Imielinski, Gouri Nanjangud, Charles J. Murphy, John H. Healey, Mercedes Duran, Jan Lammerding, Olivier Elemento, Dana Pe'er, Lewis C. Cantley, Simon N. Powell, Pragya Shah, Subramanian Venkatesan, Charles Swanton, Giulio Genovese, Roshan K. Sriram, Chantal Pauli, Peter Ly, Samuel F. Bakhoum, Kalyani Chadalavada, Christine Shaw, Julie-Ann Cavallo, Neil K. Taunk, Ashley L. Bakhoum, Nicholas McGranahan, Quincy LaPlant, Nicolai Juul Birkbak, Bryon Ngo, Mark R. Lundquist, Vinagolu K. Rajasekhar, Christine H. Chung, Nancy Y. Lee, Don W. Cleveland

المصدر: Cancer Research. 78:NG03-NG03

مصطلحات موضوعية: Cancer Research, Cancer, Biology, medicine.disease_cause, medicine.disease, Primary tumor, Metastasis, Chromosome segregation, Oncology, Downregulation and upregulation, Chromosome instability, Cancer research, medicine, Carcinogenesis, Mitosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ff7eda1e22e5283f267acdb97a104aac
https://doi.org/10.1158/1538-7445.am2018-ng03

المؤلفون: Akanksha Verma, Ryan M. Loughran, Alec C. Kimmelman, Zhiwei Yang, Nullin Divecha, David Weinkove, Elite Possik, Lewis C. Cantley, Olivier Elemento, Yilun Ma, Mark R. Lundquist, Jared L. Johnson, Tarika Vijayaraghavan, Jenny C.Y. Wong, Mark A. Rubin, Annan Yang, Katie Seo-Kyoung Hwang, Archna Ravi, Chantal Pauli, Brooke M. Emerling, Marcus D. Goncalves, Arnim Pause, John M. Asara

المصدر: Molecular Cell. 70:531-544.e9

مصطلحات موضوعية: 0301 basic medicine, mTORC1, Biology, Article, Cell Line, Mice, 03 medical and health sciences, Phosphatidylinositol Phosphates, Lysosome, Lipid droplet, Autophagy, medicine, Animals, Humans, Caenorhabditis elegans, Molecular Biology, Phosphatidylinositol 5-phosphate, Kinase, Autophagosomes, Fasting, Cell Biology, Fibroblasts, Lipid Metabolism, Cell biology, Phosphotransferases (Alcohol Group Acceptor), HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Liver, Alternative complement pathway, TFEB, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908df72e45520c0c16736f45683c6639
https://doi.org/10.1016/j.molcel.2018.03.037

المؤلفون: Mark R. Lundquist, Andrew J. Storaska, Ting-Chun Liu, Scott D. Larsen, Todd Evans, Richard R. Neubig, Samie R. Jaffrey

المصدر: Cell. 156(3)

مصطلحات موضوعية: Male, Serum Response Factor, Oncogene Proteins, Fusion, Transcription, Genetic, Cell Cycle Proteins, GTP Phosphohydrolases, Mixed Function Oxygenases, Mice, 0302 clinical medicine, Transcription (biology), Nerve Growth Factor, Anilides, Zebrafish, Cells, Cultured, 0303 health sciences, Microfilament Proteins, Intracellular Signaling Peptides and Proteins, Genes, fos, Nuclear Proteins, Lamin Type A, 3. Good health, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Biochemistry, Gene Knockdown Techniques, Benzamides, Signal transduction, Oxidoreductases, Microtubule-Associated Proteins, Oxidation-Reduction, Metabolic Networks and Pathways, Signal Transduction, Molecular Sequence Data, Active Transport, Cell Nucleus, Biology, DNA-binding protein, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, GTP-Binding Proteins, Serum response factor, medicine, Neurites, Animals, Humans, Amino Acid Sequence, Actin, 030304 developmental biology, Cell Nucleus, Biochemistry, Genetics and Molecular Biology(all), NADPH Dehydrogenase, Membrane Proteins, biology.organism_classification, Actins, Rats, Cell nucleus, Gene Expression Regulation, Trans-Activators, Carrier Proteins, Sequence Alignment, 030217 neurology & neurosurgery, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85553d3d2e05ece5f3e01ce8a405d70
https://pubmed.ncbi.nlm.nih.gov/24781641