المؤلفون: Bin Zhu (182882), Xuqing Zhang (144598), Lili Guo (303857), Matthew Rankin (10203514), Ivona Bakaj (10203511), George Ho (312730), Seunghun P. Lee (10203517), Lisa Norquay (10203520), Mark Macielag (4326814)

مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, stimulated insulin secretion, specific agonist sulprostone, rat ivgtt model, pharmacokinetic profile led, higher oral exposure, 28 , 26 , initial lead compound, 7 , potent ep3 antagonists, vivo clearance, vivo activity, vitro activity, suppressive effect, significantly lower, novel series, good selectivity, exhibited potent, ep receptors, based acylsulfonamides

Relation: https://figshare.com/articles/journal_contribution/Discovery_and_Optimization_of_7_Alkylidenyl_tetra_hydro_indazole-Based_Acylsulfonamide_EP3_Antagonists/17135917

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00594.s001