المؤلفون: Sabrina Schnur, Fabian Hans, Annika Dehne, Janina Osti, Malte-Ole Schneemann, Marc Schneider, Marius Hittinger

المصدر: Pharmaceuticals; Volume 16; Issue 5; Pages: 748

مصطلحات موضوعية: intestinal barrier integrity, transepithelial electrical resistance, pro-inflammatory cytokines, monocyte-derived macrophages, natural product, green tea, antioxidant

وصف الملف: application/pdf

Relation: Natural Products; https://dx.doi.org/10.3390/ph16050748

الاتاحة: https://doi.org/10.3390/ph16050748

المؤلفون: Duc Bach Nguyen, Thi Bich Thuy Ly, Mauro Carlos Wesseling, Marius Hittinger, Afra Torge, Andrew Devitt, Yvonne Perrie, Ingolf Bernhardt

المصدر: Cellular Physiology and Biochemistry, Vol 38, Iss 3, Pp 1085-1099 (2016)

مصطلحات موضوعية: Red blood cells, Microvesicles, Phosphatidylserine, Fluorescence imaging, Cell adhesion, Physiology, QP1-981, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.karger.com/Article/FullText/443059; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

URL الوصول: https://doaj.org/article/5bdbf16f8e3c43dd820409d64fabe851

المؤلفون: Sara Wengschick, Marius Hittinger, Katharina Rotermund, Ralf-Kilian Zäh, Jessica Gillmann, Daniel Primavessy

المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 174:101-105

مصطلحات موضوعية: Biological Availability, Pharmaceutical Science, General Medicine, Hyaluronic Acid, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92e4bc19fc2112577ee7a26bd9967b2
https://doi.org/10.1016/j.ejpb.2022.03.016

المؤلفون: Julia Katharina Metz, Marius Hittinger, Claus-Michael Lehr

المصدر: In vitro models

مصطلحات موضوعية: 3R Principle, Orally inhaled drug products, Reviews, OECD guidelines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8690f7e467f48b10f22c3dd478c58cae
http://europepmc.org/articles/PMC8688684

المؤلفون: Sabrina Schnur, Vanessa Wahl, Julia K. Metz, Jessica Gillmann, Fabian Hans, Katharina Rotermund, Ralf-Kilian Zäh, Dietmar A. Brück, Marc Schneider, Marius Hittinger

مصطلحات موضوعية: Efcacy outcome pathways, Cell-based co-culture, Chronic infammation of GI-tract, Drug testing, IVIVC

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202824e1989fd64b1bb65ed5e504b39f

المؤلفون: Julia Metz, Katharina Knoth, Henrik Groß, Claus-Michael Lehr, Carolin Stäbler, Udo Bock, Marius Hittinger

المصدر: Pharmaceutics; Volume 10; Issue 2; Pages: 56

مصطلحات موضوعية: allergy prevention, pollen, aerosol deposition in vitro system, nasal mucosa, Bepanthen ® Eye and Nose Ointment

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/pharmaceutics10020056

الاتاحة: https://doi.org/10.3390/pharmaceutics10020056

المؤلفون: Bhumika, Singh, Mohamed Essameldin, Abdelgawad, Zulfiqur, Ali, Jarrod, Bailey, Elisa, Budyn, Prospero, Civita, Martin J D, Clift, John T, Connelly, Samuel, Constant, Marius, Hittinger, Helena, Kandarova, Victoria Rosalind, Kearns, Tony, Kiuru, Tomasz, Kostrzewski, Sebastian, Kress, Victoria Marsh, Durban, Claus-Michael, Lehr, Hayley, McMillan, Julia Katharina, Metz, Vivian, Monteban, Dania, Movia, Catia, Neto, Carla, Owen, Lauri, Paasonen, Kerri Anne, Palmer, Geoffrey John, Pilkington, Karen, Pilkington, Adriele, Prina-Mello, Clive, Roper, Jonathan, Sheard, Sheree, Smith, Janette Ellen, Turner, Ipsita, Roy, Melissa Anne, Tutty, Eirini, Velliou, John Malcolm, Wilkinson

المصدر: Alternatives to laboratory animals : ATLA. 49(3)

مصطلحات موضوعية: Lab-On-A-Chip Devices, Models, Animal, Animals, Humans, Coculture Techniques, Skin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::18333ba90fd4ecdb62c6bab88e1d8aa6
https://pubmed.ncbi.nlm.nih.gov/34225465

المؤلفون: Daniel Primavessy, Marius Hittinger, Marc Schneider, Claus-Michael Lehr, Julia Katharina Metz, Sabrina Schnur

المصدر: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 168

مصطلحات موضوعية: Cell specific, Aerosols, Computer science, Pharmaceutical Science, Context (language use), General Medicine, In Vitro Techniques, Animal Testing Alternatives, Aerosol deposition, Species Specificity, Toxicity Tests, Animals, Humans, Lung region, Biochemical engineering, Lung, Cells, Cultured, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305f7e7ec073b1f03ec1619a434723ab
https://pubmed.ncbi.nlm.nih.gov/34438019

المؤلفون: Julia Katharina Metz (10092366), Birgit Wiegand (10092369), Sabrina Schnur (10092372), Katharina Knoth (10092375), Nicole Schneider-Daum (805616), Henrik Groß (10092378), Glenn Croston (1786525), Torsten Michael Reinheimer (10092381), Claus-Michael Lehr (152441), Marius Hittinger (1558720)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences not elsewhere classified, alveolar epithelium, ARDS, hydrocortisone, paracellular permeability, TEER, Three Rs

Relation: https://figshare.com/articles/journal_contribution/Supplemental_Material_sj-docx-1-atl-10_1177_0261192920983015_-_Modulating_the_Barrier_Function_of_Human_Alveolar_Epithelial_hAELVi_Cell_Monolayers_as_a_Model_of_Inflammation/13709100

الاتاحة: https://doi.org/10.25384/sage.13709100.v2

المؤلفون: Marius Hittinger, Torsten M. Reinheimer, Julia Katharina Metz, Henrik Groß, Sabrina Schnur, Glenn E Croston, Claus-Michael Lehr, Nicole Schneider-Daum, Birgit Wiegand, Katharina Knoth

المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.

المصدر: Alternatives to laboratory animals : ATLA
England

مصطلحات موضوعية: ARDS, Alveolar Epithelium, Cell, alveolar epithelium, Inflammation, Pharmacology, Toxicology, General Biochemistry, Genetics and Molecular Biology, Permeability, medicine, Humans, hydrocortisone, Barrier function, TEER, Lung, Chemistry, SARS-CoV-2, COVID-19, General Medicine, medicine.disease, In vitro, Three Rs, Medical Laboratory Technology, medicine.anatomical_structure, paracellular permeability, Alveolar Epithelial Cells, Tumor necrosis factor alpha, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94a64dc10ddc07f0397ddf372f8a953
https://pubmed.ncbi.nlm.nih.gov/33513307

المؤلفون: Prospero Civita, Hayley McMillan, Catia Neto, Sheree Smith, Vivian Monteban, Lauri Paasonen, Victoria Kearns, Bhumika Singh, Kerri Palmer, Mohamed Essameldin Abdelgawad, Julia Katharina Metz, Martin J. D. Clift, Samuel Constant, Jarrod Bailey, Claus-Michael Lehr, Ipsita Roy, Adriele Prina-Mello, Karen Pilkington, Geoffrey J. Pilkington, Dania Movia, Melissa Anne Tutty, Tony Kiuru, Elisa Budyn, Zulfiqur Ali, John Malcolm Wilkinson, Tomasz Kostrzewski, Victoria Marsh Durban, Carla Owen, Jonathan Sheard, Helena Kandarova, Clive Roper, Eirini Velliou, John T. Connelly, Janette Ellen Turner, Marius Hittinger, Sebastian Kress

المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.

المصدر: Alternatives to laboratory animals : ATLA
England
ATLA-ALTERNATIVES TO LABORATORY ANIMALS
ATLA Alternatives to Laboratory Animals

مصطلحات موضوعية: 0301 basic medicine, animal replacement, media_common.quotation_subject, organoid, Toxicology, Organ-on-a-chip, General Biochemistry, Genetics and Molecular Biology, Session (web analytics), 3Rs, 03 medical and health sciences, 0302 clinical medicine, Promotion (rank), microphysiological system, media_common, organ-on-a-chip, Animal Welfare (journal), animal-free, 3-D, in vitro, General Medicine, Human physiology, tissue microenvironment, Three Rs, Variety (cybernetics), Medical Laboratory Technology, 030104 developmental biology, 030220 oncology & carcinogenesis, Engineering ethics, new approach methodologies, Psychology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8988ab9c4803495a5cb1c9d4864c2090
https://cronfa.swan.ac.uk/Record/cronfa57289/Download/57289__20529__872b5658a37a4c01a75e6229a0ad1494.pdf

المؤلفون: Ralf-Kilian Zäh, Udo Bock, Henrik Groß, Birgit Wiegand, Hans Smola, Katharina Knoth, Barbara Veldung, Marius Hittinger, Dominic Burgio, Claus-Michael Lehr

المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.

المصدر: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
England

مصطلحات موضوعية: Quality Control, skin, Tritiated water, Skin Absorption, Human skin, Dermatology, Administration, Cutaneous, 01 natural sciences, Permeability, 010309 optics, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Psoriasis, 0103 physical sciences, Stratum corneum, medicine, Electric Impedance, Humans, quality control, Transdermal, Skin, Transepidermal water loss, integumentary system, Chemistry, in vitro, Atopic dermatitis, Permeation, medicine.disease, medicine.anatomical_structure, transdermal electrical resistance, Biomedical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1fc257cdfcfae1586a8fd11a6d7df2
https://pubmed.ncbi.nlm.nih.gov/33404151

المؤلفون: Benedikt C. Huck, Xabier Murgia, Sarah Frisch, Marius Hittinger, Alberto Hidalgo, Brigitta Loretz, Claus-Michael Lehr

المصدر: Advanced Drug Delivery Reviews. 183:114141

مصطلحات موضوعية: Mucus, Drug Delivery Systems, Mucins, Humans, Pharmaceutical Science, Rheology, Lung

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c1a2e17e61c6ef646d3b8b7f57c62
https://doi.org/10.1016/j.addr.2022.114141

المؤلفون: Marius Hittinger, Xabier Murgia, Katherina Sewald, Claus-Michael Lehr, Konrad Schwarzkopf, Laura Müller, Susanne Häussler, Lorenz Siebenbürger, Armin Braun, Carsten Börger, Sabine Wronski

المساهمون: Publica, HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.

المصدر: The Journal of antimicrobial chemotherapy
England

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), airway device, medicine.drug_class, 030106 microbiology, Antibiotics, Context (language use), Microbial Sensitivity Tests, medicine.disease_cause, Cystic fibrosis, Microbiology, 03 medical and health sciences, fluids and secretions, antibiotic, Tobramycin, medicine, Humans, Pharmacology (medical), Pharmacology, Colistin, Pseudomonas aeruginosa, Chemistry, Biofilm, diffusion, biochemical phenomena, metabolism, and nutrition, respiratory system, medicine.disease, Mucus, Anti-Bacterial Agents, Trachea, 030104 developmental biology, Infectious Diseases, Biofilms, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7523ebcfe25639de84e60db0166d118b
https://doi.org/10.1093/jac/dky241

المؤلفون: Claus-Michael Lehr, Marius Hittinger, Nicole Schneider-Daum

المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 118:73-78

مصطلحات موضوعية: 0301 basic medicine, Drug, Chemistry, Pharmaceutical, media_common.quotation_subject, Cell Culture Techniques, Pharmaceutical Science, Guidelines as Topic, Inhalation Toxicology, 02 engineering and technology, Pharmacology, Risk Assessment, Tissue Culture Techniques, 03 medical and health sciences, Drug Delivery Systems, In vivo, Administration, Inhalation, Animals, Humans, Medicine, Lung, Cells, Cultured, media_common, Aerosols, Inhalation, business.industry, General Medicine, 021001 nanoscience & nanotechnology, 030104 developmental biology, Risk analysis (engineering), Drug delivery, 0210 nano-technology, business, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0711d8ad473d87fc197e808a1d4fda57
https://doi.org/10.1016/j.ejpb.2017.02.019

المؤلفون: Katharina Knoth, Julia Katharina Metz, Marius Hittinger, Markus Limberger, Henrik Groß, Lara Scharnowske, Sabrina Schnur, Claus-Michael Lehr, Fabian Hans, Horst Zimmer

المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.

المصدر: ALTEX

مصطلحات موضوعية: 0301 basic medicine, Drug, 3R principle, media_common.quotation_subject, Inhaled drug, Administration, Oral, Context (language use), 02 engineering and technology, Pharmacology, Excipients, 03 medical and health sciences, Inhibitory Concentration 50, In vivo, Cell Line, Tumor, Administration, Inhalation, Ic50 values, in vitro in vivo correlation, Medicine, Humans, lungs, media_common, business.industry, aerosol medicine, General Medicine, Human cell, 021001 nanoscience & nanotechnology, Medical Laboratory Technology, 030104 developmental biology, Pharmaceutical Preparations, Toxicity, Drug delivery, pulmonary drug development, 0210 nano-technology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf40f2b70e991be8a32b92eb1b1bf1a
https://hdl.handle.net/10033/622170

المؤلفون: Daniel Primavessy, Sarah Barthold, Henrik Groß, Alexander Zapp, Marc Schneider, Marius Hittinger

المصدر: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142

مصطلحات موضوعية: Starch, Chemistry, Pharmaceutical, Pharmaceutical Science, Nanoparticle, 02 engineering and technology, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Delivery Systems, Polysaccharides, medicine, Acetone, Bovine serum albumin, Particle Size, Active ingredient, Drug Carriers, Chromatography, biology, food and beverages, Serum Albumin, Bovine, General Medicine, 021001 nanoscience & nanotechnology, Maltodextrin, chemistry, Solubility, Poloxamer 407, Drug delivery, biology.protein, Solvents, Nanoparticles, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, Biotechnology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48871c055865a1e36725e1ca36943223
https://pubmed.ncbi.nlm.nih.gov/31288078

المؤلفون: Marius Hittinger, Claus-Michael Lehr, Nicole Schneider-Daum, Xabier Murgia

المصدر: Biological Responses to Nanoscale Particles ISBN: 9783030124601

مصطلحات موضوعية: Physiological function, Lung, medicine.anatomical_structure, Chemistry, Epithelial transport, Biophysics, medicine, Context (language use), Particle transport

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fc4690f8dc4bef414da8d1f63cf79e46
https://doi.org/10.1007/978-3-030-12461-8_7

المؤلفون: Gareth Griffiths, Remi Hendrix-Jastrzebski, Claus-Michael Lehr, Urska Repnik, Robert Bals, Sandra Sapich, Tobias May, Dagmar Wirth, Nicole Schneider-Daum, Marius Hittinger

المصدر: Alternatives to laboratory animals : ATLA. 46(2)

مصطلحات موضوعية: 0301 basic medicine, mouse cell line, Cellular differentiation, Toxicology, Occludin, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, Electric Impedance, Animals, Cytotoxicity, Cells, Cultured, Tight Junction Proteins, Tight junction, Chemistry, respiratory in vitro model, Lentivirus, Cell Differentiation, General Medicine, Phenotype, In vitro, Three Rs, Cell biology, Mice, Inbred C57BL, Medical Laboratory Technology, 030104 developmental biology, Cell culture, Paracellular transport, Alveolar Epithelial Cells, cytotoxicity, pulmonary drug delivery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a13f33228c5e5b4bd88f6435f1e7e10
https://pubmed.ncbi.nlm.nih.gov/29856645

المؤلفون: Henrik Groß, Udo Bock, Katharina Knoth, Julia Katharina Metz, Marius Hittinger, Carolin Stäbler, Claus-Michael Lehr

المساهمون: HIPS, Helmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus 8.1, 66123 Saarbrücken, Germany., HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany., HIPS, Helmholtz-Institute für pharmazeutische Forschung Saarland, Universitätscampus E8.1, 66123 Saarbrücken, Germany.

المصدر: Pharmaceutics
Pharmaceutics, Vol 10, Iss 2, p 56 (2018)
Pharmaceutics; Volume 10; Issue 2; Pages: 56

مصطلحات موضوعية: 0301 basic medicine, Ragweed, nasal mucosa, lcsh:RS1-441, Pharmaceutical Science, Mucous membrane of nose, Pharmacology, medicine.disease_cause, Article, lcsh:Pharmacy and materia medica, 03 medical and health sciences, 0302 clinical medicine, Pollen, medicine, otorhinolaryngologic diseases, Nose, Aerosolization, aerosol deposition in vitro system, biology, Chemistry, allergy prevention, food and beverages, Penetration (firestop), biology.organism_classification, medicine.disease, In vitro, eye diseases, stomatognathic diseases, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, pollen, Bepanthen® Eye and Nose Ointment, Hay fever

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fb09e94d679ec198972f8ec48380e6
https://hdl.handle.net/10033/621512