المؤلفون: Marina Zieger, Florie Borel, Cynthia Greer, Gwladys Gernoux, Meghan Blackwood, Terence R. Flotte, Christian Mueller

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 425-438 (2022)

مصطلحات موضوعية: AAV, COPD, α1-antitrypsin deficiency, genetic lung disease, emphysema, SERPINA1, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S232905012200050X; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/dd33fcbe12cd471e89896bea164e7f7b

المؤلفون: Allison M. Keeler, Marina Zieger, Carson Semple, Logan Pucci, Alessandra Veinbachs, Robert H. Brown, Jr., Christian Mueller, Mai K. ElMallah

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 246-257 (2020)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050119301561; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/4e71710627904a1bafeb76c2d22231b7

المؤلفون: Lolita Petit, Shan Ma, Joris Cipi, Shun-Yun Cheng, Marina Zieger, Nissim Hay, Claudio Punzo

المصدر: Cell Reports, Vol 23, Iss 9, Pp 2629-2642 (2018)

مصطلحات موضوعية: hexokinase-2, aerobic glycolysis, oxidative phosphorylation, rods, cones, rod metabolism, metabolic coupling, retinitis pigmentosa, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718307113; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/916cd834449f41b29b5ee5f1be4232ab

المؤلفون: Marina Zieger, Peter K Ahnelt, Pavel Uhrin

المصدر: PLoS ONE, Vol 9, Iss 9, p e106562 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4156323?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fc3297d91ad340f68da2ccc98cfb3a47

المؤلفون: Deniz Kent, Soon Seng Ng, Payam Khoshkenar, Adam Syanda, Chao Zheng Li, Marina Zieger, Stephanie Hatch, Joe Segal, Samuel Blackford, Kaixing Le, Vivek Chowdary, Taylor Ismaili, Davide Danovi, Patrick Lewis, Sunil Sahdeo, Daniel Ebner, Christian Mueller, S. Tamir Rashid

مصطلحات موضوعية: nervous system diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8daaf1f53f7f2962db34f88649f13a
https://doi.org/10.21203/rs.3.rs-1283764/v1

المؤلفون: Gwladys Gernoux, Marina Zieger, Terence R. Flotte, Christian Mueller, Alisha M. Gruntman, Meghan Blackwood

المصدر: Molecular Therapy

مصطلحات موضوعية: Genetic enhancement, viruses, Gene Expression, medicine.disease_cause, T-Lymphocytes, Regulatory, 0302 clinical medicine, Transduction, Genetic, Drug Discovery, Vector (molecular biology), Transgenes, gene transfer, Adeno-associated virus, 0303 health sciences, Immunity, Cellular, tolerance, Muscles, Gene Transfer Techniques, AAV, Dependovirus, gene therapy, Cell biology, medicine.anatomical_structure, regulatory T cells, Organ Specificity, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, T cell, Transgene, Genetic Vectors, Tregs, adeno-associated virus, Biology, Injections, Intramuscular, 03 medical and health sciences, Immune system, Immunity, exhaustion, Genetics, medicine, Animals, Humans, Lymphocyte Count, Molecular Biology, 030304 developmental biology, Pharmacology, exhausted T cells, immunity, Macaca mulatta, Immunity, Humoral, Alipogene tiparvovec, Capsid Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e987d236ce1c220739cc6dee31e27fdb
http://europepmc.org/articles/PMC7054721

المؤلفون: Marina Zieger, Robert H. Brown, Mai K. ElMallah, Allison M. Keeler, Alessandra Veinbachs, Logan A Pucci, Christian Mueller, Carson Semple

المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 246-257 (2020)

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, lcsh:QH426-470, SOD1, Article, 03 medical and health sciences, 0302 clinical medicine, Genetics, Medicine, Gene silencing, Respiratory function, lcsh:QH573-671, Respiratory system, Amyotrophic lateral sclerosis, Molecular Biology, Lung, lcsh:Cytology, business.industry, medicine.disease, lcsh:Genetics, 030104 developmental biology, medicine.anatomical_structure, Respiratory failure, nervous system, 030220 oncology & carcinogenesis, Breathing, Molecular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2473a2c85b15047a4ae3881fc2a9ebe2
http://europepmc.org/articles/PMC6962641

المؤلفون: Michael S. Packer, Vivek Chowdhary, Genesis Lung, Lo-I Cheng, Yvonne Aratyn-Schaus, Dominique Leboeuf, Sarah Smith, Aalok Shah, Delai Chen, Marina Zieger, Brian J. Cafferty, Bo Yan, Giuseppe Ciaramella, Francine M. Gregoire, Christian Mueller

المصدر: Mol Ther

مصطلحات موضوعية: Pharmacology, Gene Editing, Adenine, Cytosine, Mice, alpha 1-Antitrypsin, alpha 1-Antitrypsin Deficiency, Drug Discovery, Liposomes, Mutation, Genetics, Molecular Medicine, Animals, Humans, Nanoparticles, Original Article, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36644562d320c3f61f413b126663bc6b
https://pubmed.ncbi.nlm.nih.gov/35121111

المؤلفون: Marina, Zieger, Florie, Borel, Cynthia, Greer, Gwladys, Gernoux, Meghan, Blackwood, Terence R, Flotte, Christian, Mueller

المصدر: Molecular therapy. Methodsclinical development. 25

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::38ad3d92ec1a09c701925029cba7d73e
https://pubmed.ncbi.nlm.nih.gov/35592360

المؤلفون: Florie Borel, Weiying Li, Alisha M. Gruntman, Gabriella Oliveira, Mai K. ElMallah, Airiel M. Davis, Huaming Sun, Terence R. Flotte, Christian Mueller, Andrew M. Hoffman, Michael H. Brodsky, Brynn H Cardozo, Marina Zieger, Andrew Cox

المصدر: Proceedings of the National Academy of Sciences. 115:2788-2793

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, education.field_of_study, Multidisciplinary, biology, Elastase, Population, Disease, Phenotype, 3. Good health, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030228 respiratory system, Genome editing, Neutrophil elastase, Immunology, Genetic model, biology.protein, CRISPR, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d28774572eadad4fe78980820ee7019
https://doi.org/10.1073/pnas.1713689115

المؤلفون: Marina Zieger, Allison M. Keeler, David D. Fuller, Jeffrey Salemi, Barry J. Byrne, Donghai Liu, Mai K. ElMallah, Ronghua ZhuGe, Karl D. Bellve, Lang Xiong

المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology. 312:L873-L881

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Physiology, Disease, Biology, 03 medical and health sciences, chemistry.chemical_compound, Physiology (medical), Internal medicine, medicine, Glycogen storage disease, chemistry.chemical_classification, Pulmonary mechanics, Glycogen, nutritional and metabolic diseases, Cell Biology, Airway smooth muscle, respiratory system, medicine.disease, respiratory tract diseases, 030104 developmental biology, Enzyme, Endocrinology, chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a38ec1ccf1ec214c2579d6b48ac4a68c
https://doi.org/10.1152/ajplung.00568.2016

المؤلفون: Richard T. Lee, Xun Jia, Rita M. Cantor, Zeneng Wang, Marina Zieger, J. Mark Brown, Christian Mueller, Rebecca C. Schugar, Mark J. Graham, Hooman Allayee, Aika Miikeda, Yonghong Meng, Weifei Zhu, Aldons J. Lusis, Stanley L. Hazen, Diana M. Shih

المصدر: Arterioscler Thromb Vasc Biol

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Trimethylamine N-oxide, Flavin-containing monooxygenase, 030204 cardiovascular system & hematology, Polymerase Chain Reaction, Article, Choline, 03 medical and health sciences, chemistry.chemical_compound, Methylamines, Mice, Random Allocation, 0302 clinical medicine, In vivo, Reference Values, Internal medicine, medicine, Animals, Mice, Knockout, Gene knockdown, Insulin, Lipid metabolism, Thrombosis, Atherosclerosis, Lipid Metabolism, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, chemistry, Oxygenases, Cardiology and Cardiovascular Medicine, Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094ace2e9f8797e5b15c9d42b80c02ac
https://pubmed.ncbi.nlm.nih.gov/31070450

المؤلفون: Mai K. ElMallah, Marina Zieger, Terence R. Flotte, Allison M. Keeler

المصدر: J Inherit Metab Dis

مصطلحات موضوعية: Male, medicine.medical_specialty, Mitochondrial Diseases, Respiratory rate, Genetic Vectors, Gene Expression, Article, Lipid Metabolism, Inborn Errors, 03 medical and health sciences, Mice, Muscular Diseases, Transduction, Genetic, Internal medicine, Carnitine, Genetics, Respiratory muscle, Medicine, Animals, Congenital Bone Marrow Failure Syndromes, Respiratory function, Respiratory system, Intramyocellular lipids, Peak flow meter, Genetics (clinical), 030304 developmental biology, measurement_unit, Mice, Knockout, 0303 health sciences, business.industry, 030305 genetics & heredity, Acyl-CoA Dehydrogenase, Long-Chain, Genetic Therapy, Dependovirus, Lipid Metabolism, Endocrinology, Liver, measurement_unit.measuring_instrument, Breathing, Female, business, Respiratory Insufficiency, Respiratory minute volume

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4430d9234addcc64555d232c387d69d7
https://europepmc.org/articles/PMC6739149/

المؤلفون: Robert H. Brown, Christian Mueller, Allison Keeler‐Klunk, Mai K. ElMallah, Logan A Pucci, Angela L McCall, Marina Zieger

المصدر: The FASEB Journal. 33

مصطلحات موضوعية: business.industry, Genetic enhancement, Genetics, Cancer research, Medicine, Respiratory system, business, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::164790872090e7f07885a864a24f5814
https://doi.org/10.1096/fasebj.2019.33.1_supplement.843.11

المؤلفون: Dongsheng Guo, Katelyn Daman, Scot A. Wolfe, Marina Zieger, Christian Mueller, Sukanya Iyer, Jennifer C. J. Chen, Charles P. Emerson, Sneha Suresh, Oliver D. King, Benjamin P. Roscoe, Pengpeng Liu, Kevin Luk

المصدر: Nature

مصطلحات موضوعية: DNA End-Joining Repair, CRISPR-Associated Proteins, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerase Inhibitors, medicine.disease_cause, Genome, Article, Frameshift mutation, Myoblasts, 03 medical and health sciences, 0302 clinical medicine, CRISPR-Associated Protein 9, Gene duplication, medicine, Humans, Connectin, DNA Breaks, Double-Stranded, Frameshift Mutation, Cas9, Gene, Polymerase, Alleles, Cells, Cultured, TCAP, 030304 developmental biology, Repetitive Sequences, Nucleic Acid, 0303 health sciences, Mutation, Nuclease, Multidisciplinary, biology, gene therapy, 3. Good health, Cell biology, Muscular Dystrophies, Limb-Girdle, Hermanski-Pudlak Syndrome, CRISPR, biology.protein, HPS1, 030217 neurology & neurosurgery, Microhomology-Mediated End Joining

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914cdf521f940f269ec5749575f6d11c
https://pubmed.ncbi.nlm.nih.gov/30944467

المؤلفون: Claudio Punzo, Marina Zieger

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, genetic structures, Iodates, mTORC1, Retinal Pigment Epithelium, Biology, AMD, Mechanistic Target of Rapamycin Complex 1, Retinal Cone Photoreceptor Cells, Tuberous Sclerosis Complex 1 Protein, 03 medical and health sciences, chemistry.chemical_compound, Mice, Research Paper: Gerotarget (Focus on Aging), rod degeneration, Retinal Rod Photoreceptor Cells, Internal medicine, Geographic Atrophy, medicine, Electroretinography, Animals, Insulin, Sodium iodate, Retinal pigment epithelium, medicine.diagnostic_test, Gerotarget, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, PTEN Phosphohydrolase, Retinal, Macular degeneration, medicine.disease, cone degeneration, eye diseases, Cell biology, Enzyme Activation, Disease Models, Animal, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Oncology, chemistry, Multiprotein Complexes, sense organs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a061965f42a5afbb80512f76ed4c22b2
http://europepmc.org/articles/PMC4891071

المؤلفون: Florie, Borel, Huaming, Sun, Marina, Zieger, Andrew, Cox, Brynn, Cardozo, Weiying, Li, Gabriella, Oliveira, Airiel, Davis, Alisha, Gruntman, Terence R, Flotte, Michael H, Brodsky, Andrew M, Hoffman, Mai K, Elmallah, Christian, Mueller

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Male, Mice, Knockout, congenital, hereditary, and neonatal diseases and abnormalities, Serpina1, mouse model, Biological Sciences, Mice, Inbred C57BL, Disease Models, Animal, Mice, emphysema, Liver, Pulmonary Emphysema, alpha 1-Antitrypsin, CRISPR, Genetics, Animals, Humans, Female, alpha-1 antitrypsin, Lung

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::181bf6060d2cab349cbf3196a3020f83
https://pubmed.ncbi.nlm.nih.gov/29453277

المؤلفون: Marina Zieger, Jaimie S. Gray, Bradley H. Rosen, Nan He, Idil A. Evans, John F. Engelhardt, Shashanna R. Moll, Michael H. Brodsky, Xingshen Sun, Christian Mueller, Florie Borel, Bo Liang, Ziying Yan

المصدر: Annals of the American Thoracic Society. 15:S292-S293

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, business.industry, Alpha (ethology), Pulmonary disease, respiratory system, Abstracts, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030228 respiratory system, Immunology, Genetic model, Pi, Medicine, CRISPR, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732c1d5b9da08aa3a25ae06deda1b86c
https://doi.org/10.1513/annalsats.201806-429mg

المؤلفون: Allison M, Keeler, Donghai, Liu, Marina, Zieger, Lang, Xiong, Jeffrey, Salemi, Karl, Bellvé, Barry J, Byrne, David D, Fuller, Ronghua, ZhuGe, Mai K, ElMallah

المصدر: American journal of physiology. Lung cellular and molecular physiology. 312(6)

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Glycogen Storage Disease Type II, nutritional and metabolic diseases, Bronchi, alpha-Glucosidases, respiratory system, respiratory tract diseases, Potassium Chloride, Trachea, Mice, Animals, Albuterol, Calcium Signaling, Extracellular Space, Muscle, Skeletal, Lung, Glycogen, Methacholine Chloride, Muscle Contraction, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5539778ebe5eae3310262870141c4382
https://pubmed.ncbi.nlm.nih.gov/28336814