المؤلفون: Mark S. Tichenor, John J. M. Wiener, Navin L. Rao, Genesis M. Bacani, Jianmei Wei, Charlotte Pooley Deckhut, J. Kent Barbay, Kevin D. Kreutter, Leon Chang, Kathleen W. Clancy, Heather E. Murrey, Weixue Wang, Kay Ahn, Michael Huber, Elizabeth Rex, Kevin J. Coe, Jiejun Wu, Haopeng Rui, Kia Sepassi, Marcello Gaudiano, Mariette Bekkers, Ivo Cornelissen, Kathryn Packman, Mark Seierstad, Christos Xiouras, Scott D. Bembenek, Richard Alexander, Cynthia Milligan, Sriram Balasubramanian, Alec D. Lebsack, Jennifer D. Venable, Ulrike Philippar, James P. Edwards, Gavin Hirst

المصدر: Journal of Medicinal Chemistry. 65:14326-14336

مصطلحات موضوعية: Arthritis, Rheumatoid, Drug Discovery, Agammaglobulinaemia Tyrosine Kinase, Humans, Lupus Erythematosus, Systemic, Molecular Medicine, Protein Kinase Inhibitors, Autoimmune Diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b6932f837c19dc6e82c72e8534354a
https://doi.org/10.1021/acs.jmedchem.2c01026

المؤلفون: Anna Kuchnio, Danlin Yang, Nele Vloemans, Cassandra Lowenstein, Ivo Cornelissen, Ricardo Amorim, Chao Han, Siddharth Sukumaran, Lut Janssen, Toon Suls, Mariette Bekkers, Elena Lasorsa, Lorena Fontana, Nicole Medeiros, Bingyuan Wu, Jun Chen, Michael Feldkamp, Sheng-Jiun Wu, Habtom Habte, John Krayer, Cam Holland, M. Phillip Deyoung, Yusri A Elsayed, Ulrike Philippar

المصدر: Blood. 140:3105-3106

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1400068381b3f118949b0557ac22f5fa
https://doi.org/10.1182/blood-2022-168739

المؤلفون: Frederik J. Rombouts, Lento William, Ingrid Velter, Ann Vos, Aldo Peschiulli, Reuillon Tristan, Maria Dominguez Blanco, Matthieu Jouffroy, Lisa McQueen, Helena Steyvers, Mariette Bekkers, Cristina Altrocchi, Beth Pietrak, Seong Joo Koo, Lawrence Szewczuk, David Walker, Kathryn Packman, Ruud Bueters, Petra Vinken, Amy Johnson, Ricardo Attar, Ulrike Philippar

المصدر: Cancer Research. 82:2133-2133

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d26c71d6d913e202af7c340f376b66d7
https://doi.org/10.1158/1538-7445.am2022-2133

المؤلفون: Weimei Sun, James P. Edwards, Ricardo Attar, Tianbao Lu, Nigel Austin, Lieven Meerpoel, Ann Cai, Luc Gys, Ulrike Philippar, Maxwell D. Cummings, Kent Barbay, Peter J. Connolly, Luc Van Nuffel, Mariette Bekkers, Shen Fang

المصدر: Bioorganicmedicinal chemistry letters. 29(23)

مصطلحات موضوعية: chemistry.chemical_classification, Protease, medicine.medical_treatment, RELB, Organic Chemistry, Clinical Biochemistry, Allosteric regulation, Assay, Pharmaceutical Science, Biochemistry, Small molecule, Jurkat cells, Enzyme, chemistry, Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein, Cell Line, Tumor, Drug Discovery, medicine, Molecular Medicine, Humans, Molecular Biology, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13213f38b7f010206584e68d29659957
https://pubmed.ncbi.nlm.nih.gov/31678006

المؤلفون: Ulrike Philippar, Lorena Fontan, Ivo Cornelissen, Haopeng Rui, Sriram Balasubramanian, Marcello Gaudiano, Mariette Bekkers, Luc Van Nuffel, Tianbao Lu, John Wiener, Mark Tichenor, Tony Greway, Kathryn Packman, Bie Verbist, Yusri Elsayed, Ricardo Attar, Jacqueline Bussolari, John Gerecitano

المصدر: Cancer Research. 81:1267-1267

مصطلحات موضوعية: Cancer Research, biology, Combination therapy, CD3, breakpoint cluster region, medicine.disease, Lymphoma, chemistry.chemical_compound, medicine.anatomical_structure, Oncology, chemistry, hemic and lymphatic diseases, biology.protein, medicine, Cancer research, Bruton's tyrosine kinase, Growth inhibition, Tyrosine kinase, B cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7f55cce1586407af620b6db9d9bf1555
https://doi.org/10.1158/1538-7445.am2021-1267

المؤلفون: Yann Abraham, Bart Petrus Anna Maria Jozef Medaer, Weimei Sun, Greet Vanhoof, Haopeng Rui, Yusri Elsayed, Sriram Balasubramanian, Ulrike Philippar, Marcello Gaudiano, Jan Willem Thuring, Jenna D. Goldberg, Tianbao Lu, Jennifer Smit, Peter J. Connolly, James P. Edwards, Max Cummings, Emanuele Trella, John Gerecitano, Nele Vloemans, Ricardo Attar, Tony Greway, Katarzyna Wnuk-Lipinska, Jan Linders, Kristof Kimpe, Amy J. Johnson, Jaqueline Bussolari, Bas-jan van der Leede, Luc Van Nuffel, Mariette Bekkers, Katie Amssoms

المصدر: Blood Cancer Discovery. 1:PO-49

مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, CD3, General Medicine, medicine.disease, BCL10, Lymphoma, 03 medical and health sciences, Interleukin 10, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, hemic and lymphatic diseases, 030220 oncology & carcinogenesis, biology.protein, Cancer research, medicine, Bruton's tyrosine kinase, IL-2 receptor, Tyrosine kinase, B cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0e8109699ae1dad100496dfd36f4ec75
https://doi.org/10.1158/2643-3249.lymphoma20-po-49

المؤلفون: Ulrike Philippar, Tianbao Lu, Nele Vloemans, Mariette Bekkers, Luc Van Nuffel, Marcello Gaudiano, Katarzyna Wnuk-Lipinska, Bas-jan Van Der Leede, Katie Amssoms, Kristof Kimpe, Bart Medaer, Tony Greway, Yann Abraham, Max Cummings, Emanuele Trella, Greet Vanhoof, Weimei Sun, Jan Willem Thuring, Peter Connolly, Jan Linders, Haopeng Rui, Sriram Balasubramanian, Amy Johnson, John Gerecitano, Jenna Goldberg, James P. Edwards, Yusri Elsayed, Jennifer Smit, Jaqueline Bussolari, Ricardo Attar

المصدر: Cancer Research. 80:5690-5690

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::504dd7a5e5c4ecf52e6e466854e7daea
https://doi.org/10.1158/1538-7445.am2020-5690

المؤلفون: Ricardo Attar, Weimei Sun, Peter J. Connolly, Yann Abraham, Joannes T. M. Linders, Bart Petrus Anna Maria Jozef Medaer, Jenna D. Goldberg, L. van Nuffel, Kristof Kimpe, Marcello Gaudiano, Greet Vanhoof, Johannes Wilhelmus John F. Thuring, James P. Edwards, Nele Vloemans, Mariette Bekkers, Yusri Elsayed, John Gerecitano, Katie Amssoms, B.M. van der Leede, Tony Greway, E. Trella, Ulrike Philippar, K. Wnuk-Lipinska, Jennifer Smit, Maxwell D. Cummings, Tianbao Lu, Jacqueline Bussolari

المصدر: Hematological Oncology. 37:128-128

مصطلحات موضوعية: Cancer Research, Class (set theory), medicine.anatomical_structure, Oncology, MALT1 protease, business.industry, medicine, Cancer research, Hematology, General Medicine, business, B cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7d6c0cefd5ac788558266b0caa15d9c6
https://doi.org/10.1002/hon.88_2629

المؤلفون: Nathaniel Gray, Qi Qiao, Ulrike Philippar, Mariette Bekkers, Gabriella Casalena, David L. Scott, Hao Wu, Lorena Fontan, Matthew Durant, Ilkay Us, John M. Hatcher, Ari Melnick, Spandan Chennamadhavuni

المصدر: Cancer Research. 77:LB-303

مصطلحات موضوعية: Cancer Research, Mutation, biology, Chemistry, Kinase, breakpoint cluster region, Syk, Germinal center, medicine.disease_cause, medicine.disease, Oncology, immune system diseases, hemic and lymphatic diseases, Cancer research, medicine, biology.protein, Bruton's tyrosine kinase, Primary mediastinal B-cell lymphoma, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dfe2a42993fbde2d8d1b603a1db1478d
https://doi.org/10.1158/1538-7445.am2017-lb-303

المؤلفون: Said Akzinnay, Sophie Descamps, Christophe Adelinet, Jeroen Van De Ven, Thierry François Alain Jean Jousseaume, Lieven Meerpoel, Etienne Daras, Javier Astray Gandara, Nele Van Slycken, Inge Boeckx, Marine Bourgeois, Laurence Anne Mevellec, Berthold Wroblowski, Guillaume Jean Maurice Mercey, Jorge Vialard, Mariette Bekkers, Elisabeth Thérèse Jeanne Pasquier, Aurélie Luguern, Jeanty Matthieu Ludovic, Ron Gilissen, Tinne Verhulst

المصدر: Cancer Research. 74:4745-4745

مصطلحات موضوعية: Cancer Research, biology, Kinase, Chemistry, Autophosphorylation, Ligand (biochemistry), Fusion protein, Receptor tyrosine kinase, Oncology, Protein kinase domain, biology.protein, Cancer research, ROS1, Kinase activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::85e989182ba8b5372717f9c85e176ede
https://doi.org/10.1158/1538-7445.am2014-4745

المؤلفون: Mariette Bekkers, Menelas N. Pangalos, Liesbet van der Helm, David Ashton, Jean-Marc Neefs, Erwin Fraiponts, Marijke Somers, Robert Gordon, Peter Verhasselt

المصدر: The Journal of biological chemistry. 274(13)

مصطلحات موضوعية: Dipeptidase, Glutamate Carboxypeptidase II, Dipeptidyl Peptidase 4, Molecular Sequence Data, Carboxypeptidases, Transfection, Biochemistry, Complementary DNA, Glutamate carboxypeptidase II, Tumor Cells, Cultured, Gene family, Animals, Humans, Northern blot, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, Molecular Biology, Integral membrane protein, In Situ Hybridization, Fluorescence, COS cells, biology, Base Sequence, Chromosomes, Human, Pair 11, Chromosome Mapping, Cell Biology, Sequence Analysis, DNA, Carboxypeptidase, Molecular biology, Neoplasm Proteins, Alternative Splicing, Antigens, Surface, COS Cells, biology.protein, Sequence Alignment, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fc7ffd9c337ceb7015d0053b9589fc
https://pubmed.ncbi.nlm.nih.gov/10085079