المؤلفون: Kimberly Chambert, Marco Kessler, Yan Chen, Nisha Perez, Mark G. Currie, Maria D. Ribadeneira

المصدر: Journal of Clinical Gastroenterology. 56:218-223

مصطلحات موضوعية: medicine.medical_specialty, Saliva, medicine.drug_class, Proton-pump inhibitor, Pilot Projects, Gastroenterology, Bile Acids and Salts, Refractory, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Internal medicine, medicine, Humans, Bile acid, business.industry, Reflux, Proton Pump Inhibitors, medicine.disease, humanities, digestive system diseases, Pathophysiology, Treatment Outcome, Gastroesophageal Reflux, GERD, business, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0786f4a56b721438d5549dd283e92889
https://doi.org/10.1097/mcg.0000000000001525

المؤلفون: Marc K. Hellerstein, Patrick Kelly, Kiran Dole, Lars Johansson, Kelvin W. Li, Eric Q. Wu, Carine Beysen, Terry E O’Reilly, Marcus Hompesch, Linda Morrow, Wei Lu, Patricia Schroeder, Julie Brevard, Maria D. Ribadeneira

المصدر: Diabetes, Obesity & Metabolism

مصطلحات موضوعية: Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Placebo, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Non-alcoholic Fatty Liver Disease, Internal medicine, drug mechanism, pharmacodynamics, randomized trial, Internal Medicine, medicine, Humans, Obesity, Dosing, phase I−II study, Randomized Controlled Trials as Topic, biology, business.industry, Lipogenesis, Fatty liver, Original Articles, medicine.disease, drug development, Fatty acid synthase, Liver, Tolerability, biology.protein, fatty liver disease, Female, Original Article, Liver function, Fatty Acid Synthases, Steatosis, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a61fcfec38047f5f2606d94d67ebcaf
https://doi.org/10.1111/dom.14272

المؤلفون: Sanjeev Forsyth, Patricia Schroeder, James Geib, Leela Vrishabhendra, Diamantis G. Konstantinidis, Kari LaSalvia, Maria D. Ribadeneira, Eric Wu, Patrick Kelly, Theodosia A. Kalfa

المصدر: Clinical pharmacology in drug development. 11(5)

مصطلحات موضوعية: Adult, Hemoglobins, Dose-Response Relationship, Drug, Double-Blind Method, Pyruvate Kinase, Pharmaceutical Science, Humans, Pharmacology (medical), Anemia, Sickle Cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0854a3515e0133ada0caf302390a1f3a
https://pubmed.ncbi.nlm.nih.gov/35019238

المؤلفون: Patricia Schroeder, Keertik Fulzele, Sanjeev Forsyth, Maria D. Ribadeneira, Sylvie Guichard, Erik Wilker, C. Gary Marshall, Adam Drake, Rose Fessler, Diamantis G. Konstantinidis, Katie G. Seu, Theodosia A. Kalfa

المصدر: The Journal of pharmacology and experimental therapeutics. 380(3)

مصطلحات موضوعية: Pharmacology, 2,3-Diphosphoglycerate, Oxygen, Hemoglobins, Adenosine Triphosphate, Erythrocytes, Hemoglobin, Sickle, Pyruvate Kinase, Pyruvic Acid, Molecular Medicine, Animals, Humans, Anemia, Sickle Cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4cbce16bbd434376b51615d214eb089
https://pubmed.ncbi.nlm.nih.gov/35031585

المؤلفون: Frans A. Kuypers, Sandra K. Larkin, Patricia Schroeder, Patrick Kelly, Maria D. Ribadeneira, R. Clark Brown, Katie Giger Seu, Theodosia A. Kalfa, Marilyn J. Telen, Santosh L. Saraf, Eric Q. Wu

المصدر: Blood. 138:8-8

مصطلحات موضوعية: business.industry, Immunology, Cell, Allosteric regulation, Inflammation, Cell Biology, Hematology, Disease, Functional health, Pharmacology, Biochemistry, medicine.anatomical_structure, medicine, In patient, medicine.symptom, business, Pyruvate kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::104c2bd95509bb000a57b3b5acbc2a42
https://doi.org/10.1182/blood-2021-147078

المؤلفون: Santosh L. Saraf, Patrick Kelly, Frans A. Kuypers, Patricia Schroeder, Eric Q. Wu, Sanjeev Forsyth, Theodosia A. Kalfa, Renae Mayer, Marilyn J. Telen, Punam Malik, Mark Lerman, Luke R. Smart, Jeremie H. Estepp, Kimberly Cruz, Maria D. Ribadeneira, R. Clark Brown

المصدر: Blood. 136:19-20

مصطلحات موضوعية: myalgia, medicine.medical_specialty, Nausea, business.industry, Immunology, Cell Biology, Hematology, Placebo, Biochemistry, Pharmacodynamics, Internal medicine, Cohort, medicine, Dosing, medicine.symptom, Adverse effect, business, Blood sampling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c1cf42e524e00d46570afb00e1e37038
https://doi.org/10.1182/blood-2020-134269

المؤلفون: Kirsten Amaral, Albert P. Li, Lili Yao, Maria D. Ribadeneira, Patricia Schroeder, Novera Alam

المصدر: Drug Metabolism and Pharmacokinetics. 35:S93

مصطلحات موضوعية: Pharmacology, Andrology, biology, Chemistry, medicine, biology.protein, Pharmaceutical Science, Pharmacology (medical), Bovine serum albumin, Cryopreservation, Pravastatin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c654a6ab373423eef8dd094a69760ae6
https://doi.org/10.1016/j.dmpk.2020.04.234

المؤلفون: Patricia Schroeder, Olga Polyanskaya, Diamantis G. Konstantinidis, Lindsey Wilson, Adam Drake, Theodosia A. Kalfa, Santosh L. Saraf, Marilyn J. Telen, Punam Malik, Lukasz Biernat, Jeremy H. Estepp, Sanjeev Forsyth, Patrick Kelly, Frans A. Kuypers, Maria D. Ribadeneira, Hyon J. Kim

المصدر: Blood. 134:616-616

مصطلحات موضوعية: Anemia, business.industry, Immunology, Cell Biology, Hematology, Pharmacology, medicine.disease, Placebo, Biochemistry, Sickle cell anemia, Pharmacokinetics, Pharmacodynamics, medicine, Dosing, Adverse effect, business, Blood sampling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::14f9ffb21ca2d460390da732bce8a434
https://doi.org/10.1182/blood-2019-121889

المؤلفون: Patrick Kelly, William B. Donnellan, Ronald Paquette, Guillermo Garcia-Manero, Patricia Schroeder, Julie Brevard, Lindsey Wilson, Jeffrey E. Lancet, Shira Dinner, Maria D. Ribadeneira, Manish R. Patel, Michael R. Grunwald, Jennifer Sweeney

المصدر: Blood. 134:3907-3907

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Nausea, Pleural effusion, Anemia, Immunology, Cell Biology, Hematology, medicine.disease, Biochemistry, Discontinuation, hemic and lymphatic diseases, Internal medicine, Pharmacodynamics, Cohort, medicine, Dosing, medicine.symptom, business, Febrile neutropenia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f931cfcd13c09783fc45a9f3ee772e3d
https://doi.org/10.1182/blood-2019-124741

المؤلفون: Maria D. Ribadeneira, Jianmin Duan, Nathalie Rioux, Maria Arias Montecillo, Hugo Poirier, Federico Colombo

المصدر: Xenobiotica. 43:915-919

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Biology, Toxicology, Biochemistry, Madin Darby Canine Kidney Cells, Inhibitory Concentration 50, Benzbromarone, chemistry.chemical_compound, Biliary excretion, Dogs, Species Specificity, Predictive Value of Tests, In vivo, Animals, Bile, Humans, Transport Vesicles, Pharmacology, Dose-Response Relationship, Drug, Multidrug resistance-associated protein 2, In vitro toxicology, General Medicine, Transfection, Fluoresceins, Multidrug Resistance-Associated Protein 2, In vitro, Rats, Dose–response relationship, chemistry, Biological Assay, Multidrug Resistance-Associated Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d553bace08e518d9cca5fb31686b432
https://doi.org/10.3109/00498254.2013.769649

المؤلفون: Maria D. Ribadeneira, Maria Sunzel, Dhaval G. Desai, Mark A. Smith, Scott W. Grimm, Diansong Zhou, Jianrong Lin

المصدر: British Journal of Clinical Pharmacology. 74:98-108

مصطلحات موضوعية: Pharmacology, CYP3A4, CYP1A2, Cmax, Biology, chemistry.chemical_compound, Pharmacokinetics, chemistry, In vivo, medicine, Midazolam, Pharmacology (medical), Inducer, Caffeine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0e2fd5945e43d44e41c7a936719b58f4
https://doi.org/10.1111/j.1365-2125.2011.04155.x

المؤلفون: Hugo Poirier, Michel Garneau, Nathalie Rioux, Maria D. Ribadeneira, Edith Bellavance, Mariève Dupuis, Jianmin Duan

المصدر: Journal of Pharmacological and Toxicological Methods. 68:346-348

مصطلحات موضوعية: Male, Drug, medicine.medical_specialty, media_common.quotation_subject, Pharmacology, Toxicology, Permeability, Rats, Sprague-Dawley, Pharmacokinetics, Tandem Mass Spectrometry, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Bile, Humans, media_common, Drug discovery, Chemistry, In vitro, High-Throughput Screening Assays, Rats, Endocrinology, Pharmaceutical Preparations, Permeability (electromagnetism), Caco-2, Drug Design, Efflux, Caco-2 Cells, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d6bc10972902d8b5a538a3b93b9157
https://doi.org/10.1016/j.vascn.2013.03.003

المؤلفون: Chu-Biao Xue, Xiaohua He, John Roderick, Ronald L Corbett, James J.-W Duan, Rui-Qin Liu, Maryanne B Covington, Mingxin Qian, Maria D Ribadeneira, Krishna Vaddi, David D Christ, Robert C Newton, James M Trzaskos, Ronald L Magolda, Ruth R Wexler, Carl P Decicco

المصدر: Bioorganic & Medicinal Chemistry Letters. 13:4299-4304

مصطلحات موضوعية: Models, Molecular, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Carboxamide, ADAM17 Protein, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Moiety, Enzyme Inhibitors, Molecular Biology, Hydroxamic acid, biology, Organic Chemistry, Quinoline, Rational design, Metalloendopeptidases, Succinates, ADAM Proteins, Kinetics, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Piperidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77c3dec33f6160bdbe29873bacd31d0
https://doi.org/10.1016/j.bmcl.2003.09.057

المؤلفون: Patrick Koch, Karl Zech, L. Alayne Burton, Andrew Parkinson, Lida Antonian, Ajay Madan, Kathleen M. Carroll, Linda A. Krueger, Edward L. LeCluyse, Greg Wagner, Jameson Forster, Maciej Czerwinski, Liang-Shang Gan, April Downey, Richard A. Graham, Daniel R. Mudra, Maria D. Ribadeneira, Li Yu, Philmore Robertson

المصدر: Drug Metabolism and Disposition. 31:421-431

مصطلحات موضوعية: CYP2B6, CYP3A, Blotting, Western, Pharmaceutical Science, Enzyme-Linked Immunosorbent Assay, Biology, Pharmacology, Mixed Function Oxygenases, Cytochrome P-450 CYP2A6, Cytochrome P-450 CYP2C8, Cytochrome P-450 Enzyme System, beta-Naphthoflavone, Cytochrome P-450 CYP1A2, Isoniazid, medicine, Cytochrome P-450 CYP3A, Humans, Enzyme Inhibitors, Enzyme inducer, CYP2A6, Cells, Cultured, CYP3A4, CYP1A2, Oxidoreductases, N-Demethylating, CYP2E1, Cytochrome P-450 CYP2C19, Cytochrome P-450 CYP2B6, Liver, Enzyme Induction, Phenobarbital, Hepatocytes, biology.protein, Aryl Hydrocarbon Hydroxylases, Rifampin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e9b32e26ca0699a3c57f5f9f45549f
https://doi.org/10.1124/dmd.31.4.421

المؤلفون: Maria D. Ribadeneira, Zelda R. Wasserman, Ruth R. Wexler, Mingxin Qian, Michael A. Pratta, Rui-Qin Liu, Wenqing Yao, Maryanne B. Covington, Micky D. Tortorella, Gade Reddy, Eric Shi, Michael Chao, Carl P. Decicco, Ronald L. Magolda, Robert C. Newton, Elizabeth C. Arner, David D. Christ

المصدر: Journal of Medicinal Chemistry. 44:3347-3350

مصطلحات موضوعية: Hydroxamic acid, biology, medicine.drug_class, Stereochemistry, Biological activity, Carboxamide, Chemical synthesis, chemistry.chemical_compound, chemistry, Enzyme inhibitor, Drug Discovery, biology.protein, medicine, Molecular Medicine, Pharmacophore, Tyrosine, Aggrecanase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::78c827efa7ca15a3aa3ef2753221d777
https://doi.org/10.1021/jm015533c

المؤلفون: Jianmin Duan, Nathalie Rioux, Michel Garneau, Maria D. Ribadeneira, Serge Bourg, Edith Bellavance

المصدر: Biopharmaceutics & Drug Disposition.

مصطلحات موضوعية: Pharmacology, business.industry, CYP3A, virus diseases, Pharmaceutical Science, General Medicine, Buspirone, Hydroxylation, chemistry.chemical_compound, chemistry, immune system diseases, In vivo, parasitic diseases, medicine, Potency, Verapamil, Pharmacology (medical), Ketoconazole, Ritonavir, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f729346c85287149259d3db31491af4
https://doi.org/10.1002/bdd.1855

المؤلفون: Nathalie, Rioux, Edith, Bellavance, Serge, Bourg, Michel, Garneau, Maria D, Ribadeneira, Jianmin, Duan

المصدر: Biopharmaceuticsdrug disposition. 34(7)

مصطلحات موضوعية: Male, Ketoconazole, Ritonavir, Verapamil, Microsomes, Liver, Animals, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Humans, Drug Interactions, Rats, Wistar, Buspirone, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f3c14e031e17d67519ec2ea0a4165e38
https://pubmed.ncbi.nlm.nih.gov/23873286

المؤلفون: Maria D. Ribadeneira, Sébastien Morin, Yves Bousquet, Martin Duplessis, Michael G. Cordingley, Michel Garneau, Daniel Rajotte, Louie Lamorte, Bounkham Thavonekham, Alex Pelletier, Patrick Deroy, Jianmin Duan, Louis Morency, Bruno Simoneau, Richard Bethell, Joannie Minville, Martin Tremblay, Paul J. Edwards, Claudio Sturino, Ted Halmos, Sonia Tremblay, Clint James

المصدر: Bioorganicmedicinal chemistry letters. 23(13)

مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biological Availability, Context (language use), Microbial Sensitivity Tests, Pyrimidinones, Pharmacology, Biochemistry, Antiviral Agents, Structure-Activity Relationship, In vivo, Drug Discovery, Potency, Animals, Humans, Molecular Biology, Benzofurans, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, HIV, In vitro, Reverse transcriptase, HIV Reverse Transcriptase, Bioavailability, Rats, Enzyme, chemistry, Molecular Medicine, Reverse Transcriptase Inhibitors, Efflux, Caco-2 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e664a134d015b3f24cda8e40f9c5469
https://pubmed.ncbi.nlm.nih.gov/23673016

المؤلفون: Bruce J. Aungst, S.‐M. Huang, Maria D. Ribadeneira, Charles J. Eyermann

المصدر: Pharmaceutical Research. 13:227-233

مصطلحات موضوعية: Pharmacology, Angiotensin receptor, Intestinal permeability, Membrane permeability, Chemistry, Organic Chemistry, Pharmaceutical Science, Permeation, medicine.disease, Angiotensin II, Intestinal absorption, Bioavailability, Biochemistry, In vivo, medicine, Biophysics, Molecular Medicine, Pharmacology (medical), Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e757398f73ce5222289a7532ae8a781
https://doi.org/10.1023/a:1016086930019

المؤلفون: Jianmin Duan, Richard Bethell, Maria D. Ribadeneira, Jonathan Massé, Nathalie Rioux, Federico Colombo, Joëlle Batonga, Christine Zouki

المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 43(7)

مصطلحات موضوعية: Drug, CYP3A, Health, Toxicology and Mutagenesis, media_common.quotation_subject, Cmax, Plasma protein binding, Pharmacology, Toxicology, Biochemistry, Drug Discovery, medicine, Cytochrome P-450 CYP3A, Humans, heterocyclic compounds, Drug Interactions, Free drug, media_common, Human liver, Dose-Response Relationship, Drug, Drug discovery, Chemistry, General Medicine, Kinetics, medicine.anatomical_structure, Pharmaceutical Preparations, Hepatocyte, Hepatocytes, Microsomes, Liver, human activities, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56284e4c3b16100081f5b0d4409de838
https://pubmed.ncbi.nlm.nih.gov/23244592