المؤلفون: Joanna Toporowska, Parth Kapoor, Maria Musgaard, Karolina Gherbi, Kathy Sengmany, Feng Qu, Mark Soave, Hsin-Yung Yen, Kjetil Hansen, Ali Jazayeri, Jonathan T. S. Hopper, Argyris Politis

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/888702c45a2847fb87032245b452250b

المؤلفون: Matthew L. Rook, Anna Ananchenko, Maria Musgaard, David M. MacLean

المصدر: Frontiers in Cellular Neuroscience, Vol 15 (2021)

مصطلحات موضوعية: gating, desensitization, acid-sensing ion channels, ASICs, molecular dynamics, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2021.761813/full; https://doaj.org/toc/1662-5102

URL الوصول: https://doaj.org/article/6d8fd25387bc46e9a27a83f62a2a78f1

المؤلفون: Chris Lindsay, Mano Sitsapesan, Wei Mun Chan, Elisa Venturi, William Welch, Maria Musgaard, Rebecca Sitsapesan

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Ryanodine Binding, RyR Channels, Triphosphate Group, Predicted Binding Energy, Rotamer Toggle, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/a9586cc41ca240059c5cc002b05afc15

المؤلفون: Matthew L Rook, Abby Williamson, John D Lueck, Maria Musgaard, David M Maclean

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: non-canonical amino acid, gating, acid-sensing ion channel, desensitization, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/51111; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/2914653332f5469fa8a86b5e76b7d4de

المؤلفون: Anna Ananchenko, Maria Musgaard

المصدر: Journal of General Physiology. 155

مصطلحات موضوعية: Physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::98810abaf19eb982891479817dd8e1c1
https://doi.org/10.1085/jgp.202213259

المؤلفون: Maria Musgaard, David M. MacLean, Matthew L. Rook

المصدر: J Physiol

مصطلحات موضوعية: 0301 basic medicine, Physiology, Chemistry, Postsynaptic Current, Gating, Hydrogen-Ion Concentration, Article, Acid Sensing Ion Channels, Coupling (electronics), 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Excitatory postsynaptic potential, Protons, Postsynaptic density, Neuroscience, 030217 neurology & neurosurgery, Function (biology), Ion channel, Acid-sensing ion channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd26cc2c771ec2f93b9c40696b63d780
https://doi.org/10.1113/jp278707

المؤلفون: Chris Lindsay, Maria Musgaard, Angela J. Russell, Rebecca Sitsapesan

المصدر: British journal of pharmacologyREFERENCES. 179(21)

مصطلحات موضوعية: Pharmacology, Mice, Simvastatin, Sheep, Muscular Diseases, Ryanodine, Animals, Ryanodine Receptor Calcium Release Channel, Acyl Coenzyme A, Rabbits, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Muscle, Skeletal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b058c40320327df26d41d281ffb5c1
https://pubmed.ncbi.nlm.nih.gov/35703154

المؤلفون: Maria Musgaard, Elisa Venturi, Rebecca Sitsapesan, Ming Lei, Charalampos Sigalas, Jianshu Hu, Carmen R. Valdivia, Abigail D. Wilson, Héctor H. Valdivia

مصطلحات موضوعية: education.field_of_study, Mutation, Physiology, Chemistry, Ryanodine receptor, Population, Wild type, Gating, musculoskeletal system, Catecholaminergic polymorphic ventricular tachycardia, medicine.disease, Ligand (biochemistry), medicine.disease_cause, Ryanodine receptor 2, Molecular biology, cardiovascular system, medicine, education, tissues

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856e051f82ca4a632db88c66eec0d104
https://ora.ox.ac.uk/objects/uuid:7421fc54-4b61-4e5e-b05c-68743bb73ce3

المؤلفون: Vardha Ismail, Linda G. Zachariassen, Annie Godwin, Mane Sahakian, Sian Ellard, Karen L. Stals, Emma Baple, Kate Tatton Brown, Nicola Foulds, Gabrielle Wheway, Matthew O. Parker, Signe M. Lyngby, Miriam G. Pedersen, Julie Desir, Allan Bayat, Maria Musgaard, Matthew Guille, Anders S. Kristensen, Diana Baralle

المصدر: Ismail, V, Zachariassen, L G, Godwin, A, Sahakian, M, Ellard, S, Stals, K L, Baple, E, Brown, K T, Foulds, N, Wheway, G, Parker, M O, Lyngby, S M, Pedersen, M G, Desir, J, Bayat, A, Musgaard, M, Guille, M, Kristensen, A S & Baralle, D 2022, ' Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID : An emerging neurodevelopmental syndrome ', American Journal of Human Genetics, vol. 109, no. 7, pp. 1217-1241 . https://doi.org/10.1016/j.ajhg.2022.05.009

مصطلحات موضوعية: Heterozygote, GLUTAMATE-RECEPTOR, INTELLECTUAL DISABILITY, Mutation, Missense, CHANNEL CONDUCTANCE, AMPA-RECEPTOR, Cohort Studies, Neurodevelopmental Disorders, SYNAPTIC PLASTICITY, LIGAND-BINDING, Genetics, LURCHER MUTATION, Humans, XENOPUS-LAEVIS, CRYSTAL-STRUCTURES, Receptors, AMPA, Genetics (clinical), SPATIAL MEMORY

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2447239acb651f58a52c081710ba7e50
https://curis.ku.dk/portal/da/publications/identification-and-functional-evaluation-of-gria1-missense-and-truncation-variants-in-individuals-with-id(9576e283-94cc-4daf-91c3-e74d23a8b35f).html

المؤلفون: Chris Lindsay, Maria Musgaard, Angela Russell, Rebecca Sitsapesan

مصطلحات موضوعية: nutritional and metabolic diseases, musculoskeletal system, tissues

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::19ca3e0a39eb62d53971baea8fa3d203
https://doi.org/10.22541/au.162729999.96753669/v1

المؤلفون: Abigail D, Wilson, Jianshu, Hu, Charalampos, Sigalas, Elisa, Venturi, Héctor H, Valdivia, Carmen R, Valdivia, Ming, Lei, Maria, Musgaard, Rebecca, Sitsapesan

المصدر: J Physiol

مصطلحات موضوعية: Mice, Sarcoplasmic Reticulum, Mutation, cardiovascular system, Tachycardia, Ventricular, Animals, Humans, Calcium, Ryanodine Receptor Calcium Release Channel, Calcium Signaling, musculoskeletal system, tissues, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::755b7b058f455089d138bc2e34587ff4
https://pubmed.ncbi.nlm.nih.gov/34676560

المؤلفون: Kristin Lees, Maria Musgaard, Siros Suwanmanee, Steven David Buckingham, Philip Biggin, David Sattelle

المصدر: PLoS ONE, Vol 9, Iss 5, p e97468 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4019635?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/0cb36386600a42a48516fbef83fdf8de

المؤلفون: Maria Musgaard, Christian J.G. Tessier, Gregory D. McCluskey, Kelly M. Burkett, Johnathon R. Emlaw, Corrie J.B. daCosta, Melissa McNulty, Yusuf Sheikh

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Ancestral reconstruction, Protein subunit, Receptors, Nicotinic, Cell Line, Evolution, Molecular, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Humans, Patch clamp, Ion channel, 030304 developmental biology, Acetylcholine receptor, 0303 health sciences, Multidisciplinary, Chemistry, Substitution (logic), Biological Sciences, Protein Subunits, Nicotinic acetylcholine receptor, Electrophysiology, Amino Acid Substitution, Biophysics, Protein Multimerization, 030217 neurology & neurosurgery, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5042582f4ad9c44e8445e6fbe7e2d842
https://doi.org/10.1073/pnas.2018731118

المؤلفون: Maria Musgaard, Tyler Couch, Dana L Kneisley, Megan Miaro, David M. MacLean, Matthew L. Rook

مصطلحات موضوعية: Agonist, Chemistry, medicine.drug_class, medicine.medical_treatment, Wild type, Glutamate receptor, medicine, Biophysics, Stimulus (physiology), Phenotype, Acid-sensing ion channel, Ion channel, Desensitization (medicine)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::624b0269a66f31c4d33a0100f9b9128e
https://doi.org/10.1101/2020.12.19.423606

المؤلفون: Ioannis Vakonakis, Julia M.C. Busch, Minos-Timotheos Matsoukas, Georgios A. Spyroulias, Philip C. Biggin, Maria Musgaard

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, ligand design, Centriole, Protein Conformation, nuclear magnetic resonance (NMR), Cell Cycle Proteins, Flagellum, Molecular Dynamics Simulation, Biochemistry, Protein–protein interaction, Small Molecule Libraries, protein-protein interaction, 03 medical and health sciences, Microtubule, biophysics, Protein oligomerization, Animals, protein-drug interaction, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Molecular Biology, Centrioles, 030102 biochemistry & molecular biology, Chemistry, Cell Biology, High-Throughput Screening Assays, inhibitor, 030104 developmental biology, centrosome, Centrosome, Biophysics, Pharmacophore, Protein Multimerization, Molecular Biophysics, Centriole assembly

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7762e833ca0dfe21a284f6ed97582601
https://pubmed.ncbi.nlm.nih.gov/32873708

المؤلفون: Christine L. Thisted, Maria Musgaard, Sergei Chavez-Abiega, Lorenzo Barrella, Anders S. Kristensen, P. C. Biggin, Charlotte Stenum-Berg

مصطلحات موضوعية: 0301 basic medicine, Receptor complex, animal structures, Allosteric modulator, Pyridones, Allosteric regulation, AMPA receptor, Crystallography, X-Ray, Protein Structure, Secondary, 03 medical and health sciences, Xenopus laevis, 0302 clinical medicine, Allosteric Regulation, Nitriles, Homomeric, Animals, Humans, health care economics and organizations, Ion channel, Pharmacology, Binding Sites, Chemistry, food and beverages, 030104 developmental biology, HEK293 Cells, nervous system, Receptors, Glutamate, Docking (molecular), Mutation, Molecular Medicine, Ionotropic glutamate receptor, Female, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89df5d7acac54ba2010d7861ca699c33
https://doi.org/10.1124/mol.119.116871

المؤلفون: Matthew L. Rook, Maria Musgaard, Abby Williamson, John D. Lueck, David M. MacLean

مصطلحات موضوعية: Chemistry, medicine.medical_treatment, medicine, Biophysics, Isomerization, Linker, Acid-sensing ion channel, Desensitization (medicine)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a9ed9e167a9ec673f57120a5bf89ab5
https://doi.org/10.7554/elife.51111.sa2

المؤلفون: Maria Musgaard, Matthew L. Rook, John D. Lueck, David M. MacLean, Abby Williamson

المصدر: eLife
eLife, Vol 9 (2020)

مصطلحات موضوعية: 0301 basic medicine, QH301-705.5, Science, medicine.medical_treatment, desensitization, acid-sensing ion channel, Gating, Molecular Dynamics Simulation, General Biochemistry, Genetics and Molecular Biology, Hazardous Substances, 03 medical and health sciences, 0302 clinical medicine, Isomerism, Pregnancy, None, Extracellular, medicine, Animals, Biology (General), Ion channel, Acid-sensing ion channel, 030304 developmental biology, Desensitization (medicine), chemistry.chemical_classification, 0303 health sciences, General Immunology and Microbiology, General Neuroscience, General Medicine, non-canonical amino acid, Hydrogen-Ion Concentration, Amino acid, Acid Sensing Ion Channels, Electrophysiology, 030104 developmental biology, chemistry, gating, Biophysics, Medicine, Female, Linker, Isomerization, Chickens, 030217 neurology & neurosurgery, Research Article, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6884da5c1ef8382ef3a232e1d5f55c

المؤلفون: Maria Musgaard, Rebecca Sitsapesan, Jianshu Hu

المصدر: Biophysical Journal. 120:150a

مصطلحات موضوعية: Biophysics, Computational biology, Homology (anthropology), Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::87454f9837d2655a4e23be69fae5ff68
https://doi.org/10.1016/j.bpj.2020.11.1096

المؤلفون: Maria Musgaard, Anna Ananchenko

المصدر: Biophysical Journal. 120:338a

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Biophysics, Arachidonic acid, Acid-sensing ion channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e330f6d2c8a6d593e0435bca5ee7dbe4
https://doi.org/10.1016/j.bpj.2020.11.2116