المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/Gating_strategy_/15083612

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s002

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/Photographs_of_HD-MAP_application_to_subjects_/15083609

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s001

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/Assessment_of_skin_strata_thickness_/15083618

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s003

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/Antibodies_used_for_flow-cytometry_analysis_of_biopsies_/15083624

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s005

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/Antibodies_used_for_immunohistochemistry_/15083627

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s006

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/S1_File_-/15083633

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s007

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/journal_contribution/S1_Methods_-/15083636

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.s008

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Influx_of_T_cells_into_the_application_site_of_antigen-coated_HD-MAPs_on_by_day_4_/15083660

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g007

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Clinical_trial_profile_/15083639

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g001

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Fig_4_-/15083651

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g004

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Skin_site_assessment_post_HD-MAP_applications_in_the_10_biopsy-group_subjects_/15083645

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g002

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Skin_site_of_two_representative_subjects_post_HD-MAP_application_/15083648

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g003

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Quantification_of_cellular_infiltration_into_the_skin_of_active_and_placebo_HD-MAP_pre-_and_post-HD-MAP_application_/15083654

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g005

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Increase_of_haematopoietic_cells_into_the_application_site_of_antigen-coated_HD-MAPs_between_day_1_and_day_4_/15083657

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g006

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Influx_of_non-T_cells_and_DCs_into_the_application_site_of_antigen-coated_HD-MAPs_by_day_4_/15083663

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g008

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/figure/Assessment_of_cell_infiltrates_/15083669

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.g009

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/dataset/Subject_demographics_of_the_skin_biopsy_groups_n_10_/15083672

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.t001

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/dataset/Summary_of_HAI_assay_results_as_geometric_mean_titres_GMTs_seroprotection_seroconversion_and_GMT-fold_increase_/15083675

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.t002

المؤلفون: Alexandra C. I. Depelsenaire (8586378), Katey Witham (8586375), Margaret Veitch (8586381), James W. Wells (276705), Christopher D. Anderson (361439), Jason D. Lickliter (8586384), Steve Rockman (6746924), Jesse Bodle (8586390), Peter Treasure (8586393), Julian Hickling (8586396), Germain J. P. Fernando (8586399), Angus H. Forster (8586372)

مصطلحات موضوعية: Microbiology, Cell Biology, Neuroscience, Physiology, Immunology, Mental Health, Infectious Diseases, Virology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, non-myeloid CD 11b, influenza vaccine, haemagglutination inhibition antibo., FA, HA-coated HD-MAP application, myeloid CD 11b, HAI antibody titres, B cell counts, ACTRN, subject, erythema responses, 61. Skin biopsies, trial Microarray patches, 1N, Local skin response, 5 μ g haemagglutinin, influenza virus vaccine, 15 μ g HA, IM

Relation: https://figshare.com/articles/dataset/Summary_of_changes_in_marker_expression_between_pre_day_1_and_post_day_4_MAP_application_/15083678

الاتاحة: https://doi.org/10.1371/journal.pone.0255282.t003