المؤلفون: Agustin Casimiro-Garcia (1776715), Christophe Allais (1470982), Agnes Brennan (2414851), Chulho Choi (1490590), Gabriela Dower (11888140), Kathleen A. Farley (1698187), Margaret Fleming (2644384), Andrew Flick (3266184), Richard K. Frisbie (4109053), Justin Hall (549247), David Hepworth (1485040), Hannah Jones (475975), John D. Knafels (1811212), Steve Kortum (11888143), Frank E. Lovering (2499421), John P. Mathias (2143423), Sashi Mohan (11888146), Paul M. Morgan (2006197), Chuenlei Parng (11888149), Kevin Parris (1621801), Nick Pullen (521677), Franklin Schlerman (2381617), John Stansfield (5576258), Joseph W. Strohbach (3018849), Felix F. Vajdos (1348371), Fabien Vincent (1776697), Hong Wang (13528), Xiaolun Wang (2252662), Robert Webster (333847), Stephen W. Wright (1490587)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Developmental Biology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, throughput screening campaign, cyclic secondary amines, build target confidence, 3 , 2 , pyrimidine carboxamides derived, ketone moiety led, diaryl ketone series, vanin ‑ 1, pyrimidine carboxamides, suitable profile, preclinical development, crystallographic methods, crystal structures, adme properties

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_a_Series_of_Pyrimidine_Carboxamides_as_Inhibitors_of_Vanin_1/17705791

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01849.s001

المؤلفون: Agustin Casimiro-Garcia (1776715), Christophe Allais (1470982), Agnes Brennan (2414851), Chulho Choi (1490590), Gabriela Dower (11888140), Kathleen A. Farley (1698187), Margaret Fleming (2644384), Andrew Flick (3266184), Richard K. Frisbie (4109053), Justin Hall (549247), David Hepworth (1485040), Hannah Jones (475975), John D. Knafels (1811212), Steve Kortum (11888143), Frank E. Lovering (2499421), John P. Mathias (2143423), Sashi Mohan (11888146), Paul M. Morgan (2006197), Chuenlei Parng (11888149), Kevin Parris (1621801), Nick Pullen (521677), Franklin Schlerman (2381617), John Stansfield (5576258), Joseph W. Strohbach (3018849), Felix F. Vajdos (1348371), Fabien Vincent (1776697), Hong Wang (13528), Xiaolun Wang (2252662), Robert Webster (333847), Stephen W. Wright (1490587)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Developmental Biology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, throughput screening campaign, cyclic secondary amines, build target confidence, 3 , 2 , pyrimidine carboxamides derived, ketone moiety led, diaryl ketone series, vanin ‑ 1, pyrimidine carboxamides, suitable profile, preclinical development, crystallographic methods, crystal structures, adme properties

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Series_of_Pyrimidine_Carboxamides_as_Inhibitors_of_Vanin_1/17705794

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01849.s002