المؤلفون: Siva Charan Devanaboyina, Peng Li, Edward L. LaGory, Carrie Poon-Andersen, Kevin D. Cook, Marcus Soto, Zhe Wang, Khue Dang, Craig Uyeda, Ryan B. Case, Veena A. Thomas, Ronya Primack, Manuel Ponce, Mei Di, Brian Ouyang, Joelle Kaner, Sheung Kwan Lam, Mina Mostafavi

المصدر: mAbs, Vol 16, Iss 1 (2024)

مصطلحات موضوعية: Antigen-antibody trafficking, fluorescence microscopy, pH/Ca2+-dependent antibodies, pharmacokinetics, TMDD, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/e01cdf9351b64b009ab7296a2022f247

المؤلفون: Shufang Liu, Sara C. Humphreys, Kevin D. Cook, Kip P. Conner, Ana R. Correia, Alex W. Jacobitz, Melissa Yang, Ronya Primack, Marcus Soto, Rupa Padaki, Mariusz Lubomirski, Richard Smith, Marissa Mock, Veena A. Thomas

المصدر: mAbs, Vol 15, Iss 1 (2023)

مصطلحات موضوعية: Monoclonal antibodies, pharmacokinetics, physiochemical, physiologically based pharmacokinetic modeling, variability, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/ba5447ad553b4a998a1ea0915308c3b4

المؤلفون: Shining Ma, Michelle So, Aazam Ghelani, Rohith Srivas, Anupama Sahoo, Robyn Hall, Wenjun Liu, Hao Wu, Sherman Yu, Shiping Lu, Elly Song, Taryn Cariaga, Marcus Soto, Hong Zhou, Chi-Ming Li, Ashutosh Chaudhry, Xin Luo, Sue J. Sohn

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: regulatory T cell (Treg), interleukin-2 (IL-2), IL-2 therapy, cytokine, T cell receptor (TCR), in vivo, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1257652/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/4b2f7fa5bd9b408db48f01f99aa68ebe

المؤلفون: Kip P. Conner, Cinthia V. Pastuskovas, Marcus Soto, Veena A. Thomas, Mylo Wagner, Dan A. Rock

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: Cytokine, IL-36R, IL-1Rrp2, TMDD, monoclonal antibody, biodistribution, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/243a6b7f7dbe4e909e8a123c532462bf

المؤلفون: Kenneth W Walker, Hossein Salimi-Moosavi, Gregory E Arnold, Qing Chen, Marcus Soto, Frederick W Jacobsen, John Hui

المصدر: PLoS ONE, Vol 14, Iss 5, p e0217061 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/14136c151f2d4a898ef46dc3efe9bd87

المؤلفون: Mei Han (127139), Yunan Wang (1692049), Kevin Cook (2181962), Noor Bala (10452112), Marcus Soto (4394767), Dan A. Rock (2309449), Josh T. Pearson (2213911), Brooke M. Rock (2824553)

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pharmacodynamic effect, off-target toxicity, Generation Biologic Design, industry places, NGB, bispecific antibodies, ADME properties, biotherapeutic, antibody, immunoaffinity purification, vivo properties, characterization, drug discovery stage, generation biologics, design processes, drug efficacy, drug development process, CE, pharmacokinetic profiles, IA

Relation: https://figshare.com/articles/journal_contribution/Universal_Automated_Immunoaffinity_Purification-CE_MS_Platform_for_Accelerating_Next_Generation_Biologic_Design/14312215

الاتاحة: https://doi.org/10.1021/acs.analchem.1c00149.s001

المؤلفون: Carrie Poon-Andersen, Hamsini Dhoolypala, Diana Wong, Marcus Soto, Hossein Salimi-Moosavi, Brian Chan, Agnieszka Kielczewska, Kevin D Cook

المصدر: Bioanalysis. 14:581-588

مصطلحات موضوعية: Immunoassay, Serum, Mice, Medical Laboratory Technology, Immunoglobulin G, Clinical Biochemistry, Animals, Antibodies, Monoclonal, General Medicine, Immunologic Tests, General Pharmacology, Toxicology and Pharmaceutics, Rats, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbfa912a44a756c1e5fac2594c6471b
https://doi.org/10.4155/bio-2022-0037

المؤلفون: Shining Ma, Michelle So, Aazam Ghelani, Rohith Srivas, Anupama Sahoo, Robyn Hall, Wenjun Liu, Hao Wu, Sherman Yu, Shiping Lu, Elly Song, Taryn Cariaga, Marcus Soto, Hong Zhou, Chi-Ming Li, Ashutosh Chaudhry, Xin Luo, Sue J. Sohn

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, regulatory T cell (Treg), interleukin-2 (IL-2), IL-2 therapy, cytokine, T cell receptor (TCR), in vivo, tolerance

Relation: https://figshare.com/articles/dataset/Table_1_Attenuated_IL-2_muteins_leverage_the_TCR_signal_to_enhance_regulatory_T_cell_homeostasis_and_response_in_vivo_xlsx/24181938

الاتاحة: https://doi.org/10.3389/fimmu.2023.1257652.s002
https://figshare.com/articles/dataset/Table_1_Attenuated_IL-2_muteins_leverage_the_TCR_signal_to_enhance_regulatory_T_cell_homeostasis_and_response_in_vivo_xlsx/24181938

المؤلفون: Hossein Salimi-Moosavi, Marcus Soto

المصدر: The AAPS journal. 24(6)

مصطلحات موضوعية: Hemoglobins, Blood Volume, Pharmaceutical Science, Animals, Tissue Distribution

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b445e457b6793bb8e76b0b2537f9950b
https://pubmed.ncbi.nlm.nih.gov/36376552

المؤلفون: Brad Herberich, Thomas Nixey, Lin Yin, Tayo Ikotun, Kelvin K. C. Sham, Jason Long, Hongyan Li, Charles Glaus, Xuhai Be, Les P. Miranda, Yuan Cheng, Marcus Soto, James R. Falsey, Bryan D. Moyer, Robert S. Foti, Christopher M. Tegley, Chawita Netirojjanakul, Linh Tran, Kip P. Conner, Jennifer Aral, Liyue Huang, Kaustav Biswas, Justin K. Murray, Bin Wu, Loren Berry, Dean Hickman, Dan A. Rock

المصدر: Drug Metabolism and Disposition. 47:1111-1121

مصطلحات موضوعية: Male, Immunoconjugates, Metabolic Clearance Rate, In silico, Drug Evaluation, Preclinical, Pharmaceutical Science, Peptide, Receptors, Fc, Mice, Neonatal Fc receptor, In vivo, medicine, Animals, Tissue Distribution, Receptor, Cryopreservation, Mice, Knockout, Voltage-Gated Sodium Channel Blockers, Pharmacology, chemistry.chemical_classification, Drug discovery, Histocompatibility Antigens Class I, NAV1.7 Voltage-Gated Sodium Channel, Antibodies, Monoclonal, In vitro, Macaca fascicularis, medicine.anatomical_structure, Biochemistry, chemistry, Hepatocyte, Hepatocytes, Administration, Intravenous, Chronic Pain, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aafa704103c2cd45fe6f198cffc5d5f
https://doi.org/10.1124/dmd.119.087742

المؤلفون: William J. McCarty, Thomas Kornecook, Jonathan Roberts, Marcus Soto, Helming Tan, Brian A. Sparling, Paul S. Andrews, Hao Chen, Charles G. Knutson, James Meyer, Stephen Schneider, Maosheng Zhang

المصدر: Journal of Pharmacology and Experimental Therapeutics. 371:476-486

مصطلحات موضوعية: Male, 0301 basic medicine, Sepiapterin, education, Endogeny, Pharmacology, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Dorsal root ganglion, In vivo, Ganglia, Spinal, medicine, Animals, Humans, Enzyme Inhibitors, Sepiapterin reductase, Pain Measurement, business.industry, Tetrahydrobiopterin, Biopterin, Rats, Alcohol Oxidoreductases, 030104 developmental biology, medicine.anatomical_structure, chemistry, Hyperalgesia, Touch, Neuropathic pain, Neuralgia, Molecular Medicine, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f03bcc2f453f7445d6302628cb7d0fe
https://doi.org/10.1124/jpet.119.257105

المؤلفون: Bryan D. Moyer, Brad Herberich, Kaustav Biswas, Kenneth W. Walker, Beth D. Youngblood, Jennifer Aral, Tayo Ikotun, Min-Hwa Jasmine Lin, Linh Tran, Thomas Kornecook, Hongyan Li, Thomas Nixey, Joseph Ligutti, Shanti Amagasu, Li Yin, Xuhai Be, Kristin L. Andrews, Christopher M. Tegley, Charles Glaus, Marcus Soto, Les P. Miranda, James R. Falsey, Jason Long, Yuan Cheng, Robert S. Foti, Hossein Salimi-Moosavi, Kelvin Sham, Christopher P Ilch, Bin Wu, Justin K. Murray, Margaret Karow, Chawita Netirojjanakul, Liz Doherty

المصدر: ACS Chemical Biology. 14:806-818

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, 010405 organic chemistry, Drug discovery, Peptide, General Medicine, Pharmacology, 01 natural sciences, Biochemistry, In vitro, 0104 chemical sciences, 03 medical and health sciences, 030104 developmental biology, chemistry, In vivo, Molecular Medicine, Potency, IC50, Linker, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::68d1aa4016111a37796e962e98dcd944
https://doi.org/10.1021/acschembio.9b00183

المؤلفون: Marcus Soto, Hossein Salimi-Moosavi, Frederick W. Jacobsen, John O. Hui, Gregory E. Arnold, Qing Chen, Kenneth W. Walker

المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0217061 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, Antibody Response, Complementarity determining region, Receptors, Fc, Pharmacology, 030226 pharmacology & pharmacy, Biochemistry, Rats, Sprague-Dawley, Mice, 0302 clinical medicine, Immune Physiology, Cricetinae, Medicine and Health Sciences, Enzyme-Linked Immunoassays, Immune Response, Mammals, Multidisciplinary, Immune System Proteins, Pharmaceutics, Antibody Isotype Determination, Eukaryota, Antibodies, Monoclonal, Vertebrates, Medicine, Antibody, Antibody Production, Research Article, Protein Binding, Primates, Drug Administration, Science, Immunology, CHO Cells, Biology, Research and Analysis Methods, Antibodies, 03 medical and health sciences, Neonatal Fc receptor, Antibody Isotype, Cricetulus, Antigen, Pharmacokinetics, Drug Therapy, In vivo, Animals, Humans, Immunoassays, Histocompatibility Antigens Class I, Organisms, Biology and Life Sciences, Proteins, Complementarity Determining Regions, Rats, 030104 developmental biology, Isoelectric point, Immunoglobulin G, Amniotes, biology.protein, Immunologic Techniques

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28f455a19d1cec86012ec17bc3e904d
http://europepmc.org/articles/PMC6533040

المؤلفون: Justin K, Murray, Bin, Wu, Christopher M, Tegley, Thomas E, Nixey, James R, Falsey, Brad, Herberich, Li, Yin, Kelvin, Sham, Jason, Long, Jennifer, Aral, Yuan, Cheng, Chawita, Netirojjanakul, Liz, Doherty, Charles, Glaus, Tayo, Ikotun, Hongyan, Li, Linh, Tran, Marcus, Soto, Hossein, Salimi-Moosavi, Joseph, Ligutti, Shanti, Amagasu, Kristin L, Andrews, Xuhai, Be, Min-Hwa Jasmine, Lin, Robert S, Foti, Christopher P, Ilch, Beth, Youngblood, Thomas J, Kornecook, Margaret, Karow, Kenneth W, Walker, Bryan D, Moyer, Kaustav, Biswas, Les P, Miranda

المصدر: ACS chemical biology. 14(4)

مصطلحات موضوعية: Male, Voltage-Gated Sodium Channel Blockers, Mice, Immunoconjugates, Drug Discovery, NAV1.7 Voltage-Gated Sodium Channel, Animals, Humans, Spider Venoms, Molecular Targeted Therapy, Peptides, Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a795b15b8b6e13088e7422d887dacec6
https://pubmed.ncbi.nlm.nih.gov/30875193

المؤلفون: Kaustav, Biswas, Thomas E, Nixey, Justin K, Murray, James R, Falsey, Li, Yin, Hantao, Liu, Jacinthe, Gingras, Brian E, Hall, Brad, Herberich, Jerry Ryan, Holder, Hongyan, Li, Joseph, Ligutti, Min-Hwa Jasmine, Lin, Dong, Liu, Brian D, Soriano, Marcus, Soto, Linh, Tran, Christopher M, Tegley, Anrou, Zou, Kannan, Gunasekaran, Bryan D, Moyer, Liz, Doherty, Les P, Miranda

المصدر: ACS chemical biology. 12(9)

مصطلحات موضوعية: Male, Models, Molecular, Voltage-Gated Sodium Channel Blockers, Mice, HEK293 Cells, Immunoconjugates, NAV1.7 Voltage-Gated Sodium Channel, Animals, Humans, Tissue Distribution, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9d9d63324300be54bf17aab5fbfa3c14
https://pubmed.ncbi.nlm.nih.gov/28800217

المؤلفون: Dwight Winters, Brooke M. Rock, Yunan Wang, Marcus Soto, Josh T. Pearson, Mei Han, Dan A. Rock

المصدر: Analytical biochemistry. 539

مصطلحات موضوعية: 0301 basic medicine, Recombinant Fusion Proteins, Biophysics, Context (language use), Mass spectrometry, 01 natural sciences, Biochemistry, Capillary electrophoresis–mass spectrometry, Chromatography, Affinity, Mass Spectrometry, 03 medical and health sciences, Mice, Capillary electrophoresis, In vivo, Animals, Molecular Biology, ADME, Chromatography, Chemistry, Protein Stability, 010401 analytical chemistry, Electrophoresis, Capillary, Cell Biology, Protein engineering, 0104 chemical sciences, Immunoglobulin Fc Fragments, Fibroblast Growth Factors, 030104 developmental biology, Quantitative analysis (chemistry), Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f6d95c723f92ebc46f5cc1d95d8275
https://pubmed.ncbi.nlm.nih.gov/29029979

المؤلفون: Christopher A. James, Ronya Primack, Kevin Salyers, Roger Pham, Marc W. Retter, Valerie Almon, James Meyer, Mylo Wagner, Marcus Soto, Manuel Ponce

المصدر: Bioanalysis. 6:2135-2146

مصطلحات موضوعية: Male, Clinical Biochemistry, Pharmacology, Analytical Chemistry, Rats, Sprague-Dawley, Matrix (chemical analysis), Mice, Pharmacokinetics, Tandem Mass Spectrometry, Drug Discovery, Animals, Benzothiazoles, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, Blood Specimen Collection, Chromatography, Chemistry, Drug candidate, Sampling (statistics), General Medicine, PK Parameters, Triazoles, Rats, Dried blood spot, Medical Laboratory Technology, Pyrimidines, Blood sampling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32bfa59d443f36c460df5cbd6324c09
https://doi.org/10.4155/bio.14.184

المؤلفون: Craig Uyeda, Marcus Soto, Jiyun S Chen, Timothy J. Carlson, Guifen Xu, Mary C. Wells, Tom Huang, Christopher A. James, Ruta Phadnis, Brian Stouch

المصدر: Bioanalysis. 4:2037-2047

مصطلحات موضوعية: Male, Bioanalysis, Clinical Biochemistry, Pharmacology, Analytical Chemistry, Rats, Sprague-Dawley, Plasma, Dogs, Species Specificity, Pharmacokinetics, Tandem Mass Spectrometry, In vivo, Lc ms ms, Animals, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, Blood Specimen Collection, Chromatography, Chemistry, Reproducibility of Results, Blood Proteins, General Medicine, Rats, Dried blood spot, Medical Laboratory Technology, Pharmaceutical Preparations, Injections, Intravenous, Dried Blood Spot Testing, Quantitative analysis (chemistry), Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d7df166535ef2767889d8e0c62a6f2
https://doi.org/10.4155/bio.12.167

المؤلفون: Marcus Soto, Dominador Calamba, Manuel Ponce, Jessica Johnson, Yu-Nien Sun, Benjamin Wu

المصدر: Pharmaceutical Research

مصطلحات موضوعية: Male, Tumor angiogenesis, Rodent, Recombinant Fusion Proteins, Pharmaceutical Science, Receptors, Fc, Pharmacology, Kidney, law.invention, Angiopoietin-2, Rats, Sprague-Dawley, Mice, Neonatal Fc receptor, law, peptibody, biology.animal, nephrectomy, Angiopoietin-1, Animals, Humans, Pharmacology (medical), Tie2 Receptor, Mice, Knockout, neonatal Fc receptor, Neovascularization, Pathologic, biology, Mechanism (biology), Chemistry, Histocompatibility Antigens Class I, Organic Chemistry, AMG 386, Antibodies, Monoclonal, clearance mechanism, Receptor, TIE-2, Fusion protein, Rats, Mice, Inbred C57BL, embryonic structures, Immunology, cardiovascular system, Recombinant DNA, Molecular Medicine, Spleen, Research Paper, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb63f6d41fd3516a611762a1a308e35c
https://doi.org/10.1007/s11095-011-0650-z

المؤلفون: Sarah Walter, Roger Pham, Savannah J Kerr, Joel D Esmay, Xiaochun Zhu, Michael E. Fitzsimmons, Raju Subramanian, Gary L Skiles, Marcus Soto, Steven W Louie, Sarah F Wilson, Katheryne Z Edson, Mylo Wagner

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 44(8)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, medicine.drug_class, 030232 urology & nephrology, Pharmaceutical Science, Peptide, Pharmacology, Calcimimetic Agents, Kidney, Transfection, Risk Assessment, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Dogs, Pharmacokinetics, Cytochrome P-450 Enzyme System, Rats, Inbred BN, medicine, Animals, Humans, Drug Interactions, Tissue Distribution, Receptor, Biotransformation, Serum Albumin, chemistry.chemical_classification, Molecular Structure, Kidney metabolism, Membrane Transport Proteins, Metabolism, In vitro, Renal Elimination, 030104 developmental biology, Enzyme, HEK293 Cells, chemistry, Biochemistry, Liver, Administration, Intravenous, Female, Peptides, Receptors, Calcium-Sensing, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a3b78a29845db4808ed23d3bc60ec7
https://pubmed.ncbi.nlm.nih.gov/26895981