المؤلفون: Charles Mattis, Natalie Bratcher, Monika Burns, Christopher Carosino, Christina de Zafra, R. Marcus Fancher, Katrin Georgi, Candace Graff, Renee R. Hukkanen, Colena Johnson, Yanbin Lao, Amber Lange, Donna Lee, Michelle Lepherd, Sean Maguire, Mantas Malisauskas, Melinda Manuel, Sonia Miranda, Lori Reed, Rosemary Santos, Brian Sayers, David Shaw, David Shuster

المصدر: International Journal of Toxicology. 41:291-296

مصطلحات موضوعية: Primates, Drug Industry, Pharmaceutical Preparations, Drug Discovery, Drug Evaluation, Preclinical, Animals, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b10e5fddd417acb06af1f508d5bc829
https://doi.org/10.1177/10915818221101791

المؤلفون: Yueping Zhang, Petia A. Shipkova, Bethanne M Warrack, David M Nelson, Linna Wang, Runlan Huo, Jian Chen, Erika Panfen, Xue-Qing Chen, Marcus Fancher, Qian Ruan, Lisa J. Christopher, Yongjun Xue, Michael Sinz, Hong Shen

المصدر: Drug Metabolism and Disposition. :DMD-AR

مصطلحات موضوعية: Pharmacology, Pharmaceutical Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::682701f0e5a98a5ec8e72d44c0aad89e
https://doi.org/10.1124/dmd.123.001284

المؤلفون: Li Zhu, Alban Allentoff, Christine Huang, Long Yuan, Kimberly Voronin, Renuka Pillutla, Peggy Liu-Kreyche, Naiyu Zheng, R. Marcus Fancher, Ramaswamy A. Iyer, Qin C Ji

المصدر: Journal of Pharmaceutical and Biomedical Analysis. 165:198-206

مصطلحات موضوعية: Analyte, Bioanalysis, Cost-Benefit Analysis, Metabolite, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Interference (wave propagation), Mass spectrometry, 01 natural sciences, Analytical Chemistry, chemistry.chemical_compound, Dogs, MicroDose, Tandem Mass Spectrometry, Acetamides, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Spectroscopy, Chromatography, 010405 organic chemistry, Chemistry, 010401 analytical chemistry, 0104 chemical sciences, Isotope Labeling, Quinolines, Monoisotopic mass, Chromatography, Liquid, Accelerator mass spectrometry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fc68cf12dfa694920138ee93092ab9
https://doi.org/10.1016/j.jpba.2018.12.014

المؤلفون: R. Marcus Fancher, Hong Shen, Pawel D. Puszczalo, Shen-Jue Chen, Xue-Qing Chen, David J. Shuster, Cliff Chen, Zheng Yang, Yueping Zhang, Michael Sinz

المصدر: The Journal of pharmacology and experimental therapeutics. 375(1)

مصطلحات موضوعية: 0301 basic medicine, Male, Coproporphyrins, Abcg2, CYP3A, Gene Expression, Pharmacology, Kidney, 03 medical and health sciences, Solute Carrier Organic Anion Transporter Family Member 1B3, 0302 clinical medicine, In vivo, Gene expression, Intestine, Small, polycyclic compounds, Animals, Inducer, biology, Chemistry, Multidrug resistance-associated protein 2, Kidney metabolism, biochemical phenomena, metabolism, and nutrition, Hydroxycholesterols, Organic anion-transporting polypeptide, Macaca fascicularis, 030104 developmental biology, Liver, biology.protein, Molecular Medicine, Female, Rifampin, 030217 neurology & neurosurgery, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5fe69c064b860f01c0a6c8176ec465
https://pubmed.ncbi.nlm.nih.gov/32719071

المؤلفون: Michael Sinz, Yang Hong, Jinping Gan, R. Marcus Fancher, Yurong Lai, Xiaomei Gu, Lifei Wang, Yuan Tian, Hong Shen

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 48(8)

مصطلحات موضوعية: Male, Coproporphyrins, Cmax, Drug Evaluation, Preclinical, Pharmaceutical Science, Administration, Oral, Biological Availability, Pharmacology, Kidney, Excretion, Mice, Pharmacokinetics, Cyclosporin a, medicine, Distribution (pharmacology), Animals, Drug Interactions, Tissue Distribution, biology, Chemistry, Liver-Specific Organic Anion Transporter 1, Bioavailability, Probenecid, Organic anion-transporting polypeptide, Macaca fascicularis, Intestinal Absorption, Liver, Area Under Curve, biology.protein, Cyclosporine, Administration, Intravenous, Rifampin, Biomarkers, medicine.drug, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accb652d3840e2199ecade397f8fa73f
https://pubmed.ncbi.nlm.nih.gov/32482623

المؤلفون: Punit Marathe, Michael Sinz, Erika Panfen, Hong Shen, Yueping Zhang, Marcus Fancher

المصدر: Molecular pharmaceutics. 16(6)

مصطلحات موضوعية: Organic anion transporter 1, Organic Cation Transport Proteins, Estrone, Pharmaceutical Science, Organic Anion Transporters, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Solute Carrier Organic Anion Transporter Family Member 1B3, 0302 clinical medicine, In vivo, Estrone sulfate, Tandem Mass Spectrometry, Drug Discovery, medicine, Animals, Humans, Rosuvastatin, Drug Interactions, Rosuvastatin Calcium, Pitavastatin, IC50, Sulfonamides, Organic cation transport proteins, biology, Organic Cation Transporter 1, Biological Transport, 021001 nanoscience & nanotechnology, Isoquinolines, Organic anion-transporting polypeptide, Macaca fascicularis, chemistry, biology.protein, Hepatocytes, Molecular Medicine, 0210 nano-technology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37949e404d9294c9b2362eba7b09f71d
https://pubmed.ncbi.nlm.nih.gov/31039308

المؤلفون: R. Marcus Fancher, Prasad Krishnamurthy, Tongtong Liu, Xi Qiu, Cliff Chen, Hamza Kandoussi, Kristin Taylor, Sunil Sukrutharaj, Kathy Kuit, Jianing Zeng, Yurong Lai, A. David Rodrigues, Hao Jiang, Gabe Mintier, Craig Titsch, Hong Shen, Punit Marathe

المصدر: Drug Metabolism and Disposition. 44:238-249

مصطلحات موضوعية: 0301 basic medicine, Organic Cation Transport Proteins, Pharmaceutical Science, Pharmacology, Biology, Kidney, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cations, medicine, Animals, Humans, Drug Interactions, Organic cation transport proteins, HEK 293 cells, Kidney metabolism, Transporter, Metformin, In vitro, Kinetics, Macaca fascicularis, HEK293 Cells, Pyrimethamine, 030104 developmental biology, medicine.anatomical_structure, Renal physiology, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f1439b649c45f5a1763a27d77a5338
https://doi.org/10.1124/dmd.115.066852

المؤلفون: Gabe Mintier, Lun Li, Yurong Lai, Punit Marathe, Ramaswamy A. Iyer, Hong Shen, Marcus Fancher, Hong Su, David Rodrigues, Ming Yao, Tongtong Liu

المصدر: Journal of Pharmacology and Experimental Therapeutics. 353:380-391

مصطلحات موضوعية: Male, Organic anion transporter 1, Cmax, Organic Anion Transporters, Organic Anion Transporters, Sodium-Dependent, Pharmacology, Excretion, Feces, Species Specificity, In vivo, Cyclosporin a, Animals, Bile, Humans, Rosuvastatin Calcium, Sulfonamides, Symporters, biology, Chemistry, Biological Transport, In vitro, Fluorobenzenes, Organic anion-transporting polypeptide, Macaca fascicularis, HEK293 Cells, Pyrimidines, Isotope Labeling, Molecular Probes, Cyclosporine, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f09a73e6352dd244374a2683eb21baa
https://doi.org/10.1124/jpet.114.221804

المؤلفون: R. Marcus Fancher, Elizabeth A. Dierks, Jamus MacGuire, Chiuwa E. Luk, James Smalley, Kimberly A. Foster, Evan B. Janovitz, Qin Sun, Hong Cai, Maxine Fox

المصدر: Pharmacology Research & Perspectives

مصطلحات موضوعية: Metabolite, Atorvastatin, Pharmacology, biliary excretion, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, Biliary excretion, Dogs, Glucuronides, 0302 clinical medicine, medicine, Animals, Bile, Metabolomics, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, Ultrasonography, Interventional, Bile duct, Original Articles, preclinical models, drug metabolism, Ultrasound guided, Macaca fascicularis, Oxidative Stress, medicine.anatomical_structure, Neurology, chemistry, 030220 oncology & carcinogenesis, Metabolite profiling, Original Article, Bile Ducts, Glucuronide, Drug metabolism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f79809ef4f891b3ae5aa9ce039e8a0
https://doi.org/10.1002/prp2.488

المؤلفون: Long Yuan, Mingshe Zhu, Li Ma, Anne-Françoise Aubry, Qin C Ji, Lisa Dillon, Huadong Sun, Lois D. Lehman-McKeeman, R. Marcus Fancher

المصدر: Analytica chimica acta. 945

مصطلحات موضوعية: Accuracy and precision, Analyte, Bioanalysis, Metabolite, 030226 pharmacology & pharmacy, 01 natural sciences, Biochemistry, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tandem Mass Spectrometry, Environmental Chemistry, Protein precipitation, Animals, Sample preparation, Spectroscopy, Chromatography, Chemistry, 010401 analytical chemistry, Significant difference, Reference Standards, 0104 chemical sciences, Rats, Models, Chemical, Quantitative analysis (chemistry), Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db756c82938ba3009f6a5ac8c96ee424
https://pubmed.ncbi.nlm.nih.gov/27968716

المؤلفون: Ian Yates, Michael J. Hageman, Michael M. Morgen, R. Marcus Fancher, Olafur S. Gudmundsson, Kimberly A. Foster, Brice George Murri, Jon Ehrmann

المصدر: International Journal of Pharmaceutics. 434:406-412

مصطلحات موضوعية: In situ, Time Factors, Alginates, Pharmaceutical Science, chemistry.chemical_element, Absorption (skin), Rats, Sprague-Dawley, Toxicology, chemistry.chemical_compound, Glucuronic Acid, Suspensions, In vivo, Animals, Karaya Gum, Chromatography, Chemistry, Hexuronic Acids, Barium, Controlled release, Rats, Barium sulfate, Self-healing hydrogels, Feasibility Studies, Barium Sulfate, Gels

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ae30c7b259d681dac2fc3b2788fe16
https://doi.org/10.1016/j.ijpharm.2012.06.009

المؤلفون: Yue-Zhong Shu, Li Ma, Goodrich Jason, R. Marcus Fancher, Makonen Belema, Mingshe Zhu, John E. Leet, W. Griffith Humphreys, Yang Hong, Min Gao, Lopez Omar D, Van N. Nguyen, Benjamin M. Johnson, Weiping Zhao, Wenying Li, Janet Caceres-Cortes, John A. Easter, Shu Y Chang, Xiaohong Liu, Xiaohua Huang, Lawrence G. Hamann

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 44(6)

مصطلحات موضوعية: 0301 basic medicine, Male, Daclatasvir, Magnetic Resonance Spectroscopy, Pyrrolidines, Cytochrome, Stereochemistry, Metabolite, Pharmaceutical Science, Mass Spectrometry, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Mice, Dogs, Biotransformation, Cytochrome P-450 Enzyme System, medicine, Animals, Bile, Humans, Chromatography, High Pressure Liquid, Pharmacology, chemistry.chemical_classification, Mice, Inbred BALB C, biology, Imidazoles, Valine, Metabolism, Haplorhini, Rats, Macaca fascicularis, 030104 developmental biology, Enzyme, chemistry, Biochemistry, Microsome, biology.protein, Hepatocytes, Microsomes, Liver, Carbamates, Oxidation-Reduction, Nicotinamide adenine dinucleotide phosphate, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d362b783dbf18d775d89ed92b157ad
https://pubmed.ncbi.nlm.nih.gov/27029743

المؤلفون: Michael J. Hageman, Kimberly A. Foster, Roderick Marcus Fancher, Olafur S. Gudmundsson, Georgia Cornelius, Kenneth Ford, Huadong Sun, Mirek Proszynski, George Dixon

المصدر: Journal of pharmaceutical sciences. 102(8)

مصطلحات موضوعية: Male, Alginates, Pharmaceutical Science, Administration, Oral, Ibuprofen, Pharmacology, Permeability, Rats, Sprague-Dawley, Pharmacokinetics, Glucuronic Acid, In vivo, Karaya Gum, Animals, Cyclooxygenase Inhibitors, Solubility, Antihypertensive Agents, Sulfonamides, Chemistry, Hexuronic Acids, In vitro, Rats, Permeability (electromagnetism), Celecoxib, Gastric Mucosa, Delayed-Action Preparations, Drug delivery, Self-healing hydrogels, Pyrazoles, Gels, Metoprolol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c3e3916f12ff44ba97574572214ac9
https://pubmed.ncbi.nlm.nih.gov/23744594

المؤلفون: Bogdan Sleczka, Hongjian Zhang, R. Marcus Fancher, George M. Derbin, Richard Rockar, Punit Marathe

المصدر: Journal of pharmaceutical sciences. 100(7)

مصطلحات موضوعية: Male, Time Factors, Drug Evaluation, Preclinical, Pharmaceutical Science, Ph dependent, Administration, Oral, Absorption (skin), Pharmacology, Beagle, Injections, Intramuscular, Dogs, Pharmacokinetics, medicine, Animals, Gastrostomy, Gastric Juice, Chemistry, Stomach, digestive, oral, and skin physiology, Fasting, Hydrogen-Ion Concentration, Famotidine, Dietary Fats, Pentagastrin, medicine.anatomical_structure, Intestinal Absorption, Pharmaceutical Preparations, Gastric Mucosa, Models, Animal, Canine model, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf942b339e7fa3e79ffc3a0ff3c0d4f
https://pubmed.ncbi.nlm.nih.gov/21254068

المؤلفون: Punit Marathe, A. David Rodrigues, Qian Ruan, R. Marcus Fancher, Zheng Yang, Cliff Chen

المصدر: Journal of pharmaceutical and biomedical analysis. 47(2)

مصطلحات موضوعية: Anions, Indocyanine Green, genetic structures, Clinical Biochemistry, Pharmaceutical Science, Tandem mass spectrometry, High-performance liquid chromatography, Sensitivity and Specificity, Analytical Chemistry, chemistry.chemical_compound, Dogs, Liquid chromatography–mass spectrometry, Tandem Mass Spectrometry, Spectrophotometry, Drug Discovery, medicine, Animals, Bile, Coloring Agents, Spectroscopy, Chromatography, medicine.diagnostic_test, Molecular Structure, Chemistry, Selected reaction monitoring, Reproducibility of Results, Reference Standards, Liver function, Quantitative analysis (chemistry), Indocyanine green, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570daa67ce3bc925ab1e4cf0ec9479e3
https://pubmed.ncbi.nlm.nih.gov/18295429