المؤلفون: Marco C. Miotto, Steven Reiken, Anetta Wronska, Qi Yuan, Haikel Dridi, Yang Liu, Gunnar Weninger, Carl Tchagou, Andrew R. Marks

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/bc2929b1c98e4fc79d74e5bb8c72f229

المؤلفون: Haikel Dridi, Gaetano Santulli, Laith Bahlouli, Marco C. Miotto, Gunnar Weninger, Andrew R. Marks

المصدر: Biomolecules, Vol 13, Iss 9, p 1409 (2023)

مصطلحات موضوعية: mitochondria, calcium, heart failure, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/9/1409; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/048e4c96f40545ac849ee913a8e67a7a

المؤلفون: Marissa J. Stutzman, C.S. John Kim, David J. Tester, Samantha K. Hamrick, Steven M. Dotzler, John R. Giudicessi, Marco C. Miotto, Jeevan B. GC, Joachim Frank, Andrew R. Marks, Michael J. Ackerman

المصدر: Stem Cell Reports. 17:2023-2036

مصطلحات موضوعية: Induced Pluripotent Stem Cells, Isoproterenol, Arrhythmias, Cardiac, Ryanodine Receptor Calcium Release Channel, Cell Biology, NAD, Biochemistry, Mutation, Tachycardia, Ventricular, Genetics, Humans, Calcium, Myocytes, Cardiac, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb2793eea260a1df3d18391d32d49ff
https://doi.org/10.1016/j.stemcr.2022.07.002

المؤلفون: Marco C. Miotto, Gunnar Weninger, Haikel Dridi, Qi Yuan, Yang Liu, Anetta Wronska, Zephan Melville, Leah Sittenfeld, Steven Reiken, Andrew R. Marks

المصدر: Science advances. 8(29)

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e99fc05077ad8bd07acc4fdbad3d9f
https://pubmed.ncbi.nlm.nih.gov/35857850

المؤلفون: Marco C. Miotto, Andrew R. Marks

المصدر: Cell Calcium. 105:102614

مصطلحات موضوعية: Physiology, Cryoelectron Microscopy, Mutation, Calcium, Ryanodine Receptor Calcium Release Channel, Cell Biology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d903b2316c33de5ec4207918f19a3472
https://doi.org/10.1016/j.ceca.2022.102614

المؤلفون: Daphne S. Cukierman, Anastácia Sá P. da Silva, Ricardo Q. Aucélio, Sergio L.P. Castiñeiras-Filho, Thales de P. Ribeiro, Marco C. Miotto, Rachel Ann Hauser-Davis, Nicolás A. Rey, Alessandra L. M. C. da Cunha, Tiago F. Outeiro, Anna De Falco, Marcos D. Pereira, Jesus Landeira-Fernandez, Ana Beatriz Pinheiro, Claudio O. Fernández, Silvia Maisonette

المصدر: Journal of Inorganic Biochemistry. 170:160-168

مصطلحات موضوعية: Male, 0301 basic medicine, Wistar Rats, CIENCIAS MÉDICAS Y DE LA SALUD, Parkinson's disease, Stereochemistry, Drug Evaluation, Preclinical, Hydrazone, Química Inorgánica y Nuclear, 010402 general chemistry, Blood–brain barrier, 01 natural sciences, Biochemistry, Ciencias Biológicas, Inorganic Chemistry, 03 medical and health sciences, Toxicología, medicine, Animals, Mpac, Parkinson Disease, Secondary, Rats, Wistar, Chelating Agents, chemistry.chemical_classification, Metal binding, Chemistry, Hydrazones, Ciencias Químicas, Bioinorganic chemistry, Bioquímica y Biología Molecular, medicine.disease, Rats, 3. Good health, 0104 chemical sciences, Parkinson'S Disease, Medicina Básica, 030104 developmental biology, medicine.anatomical_structure, Blood-Brain Barrier, Α-Synuclein, Metal Hypothesis, α synuclein, Copper, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba64497b5ad7279ee30a2a963b34133
https://doi.org/10.1016/j.jinorgbio.2017.02.020

المؤلفون: Alberto Vela, Claudio O. Fernández, Edward I. Solomon, Lina Rivillas-Acevedo, Trinidad Arcos-López, Marco C. Miotto, Liliana Quintanar, Keith O. Hodgson, Britt Hedman, Rafael Grande-Aztatzi, Munzarin F. Qayyum

المصدر: Inorganic Chemistry

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Biophysics, chemistry.chemical_element, Plasma protein binding, Prion Protein, 010402 general chemistry, Endocytosis, 01 natural sciences, Article, Prion Proteins, Inorganic Chemistry, Metal, 03 medical and health sciences, chemistry.chemical_compound, Humans, Molecule, Physical and Theoretical Chemistry, Nuclear Magnetic Resonance, Biomolecular, Methionine, Superoxide, Otras Ciencias Químicas, Ciencias Químicas, Sulfoxide, Hydrogen-Ion Concentration, Models, Theoretical, Copper, Peptide Fragments, nervous system diseases, 0104 chemical sciences, 3. Good health, Kinetics, Crystallography, X-Ray Absorption Spectroscopy, 030104 developmental biology, chemistry, visual_art, visual_art.visual_art_medium, Cu(I), Oxidation-Reduction, CIENCIAS NATURALES Y EXACTAS, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3742f1a8ad89b7f512e7bb30602cd94b
https://doi.org/10.1021/acs.inorgchem.5b02794

المؤلفون: Elio Accardo, Claudio O. Fernández, Nicolás A. Rey, Rosana Garrido Gomes, Daphne S. Cukierman, Maria Clara R. Freitas, Anna De Falco, Mauricio Lanznaster, Marco C. Miotto

المصدر: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 23(8)

مصطلحات موضوعية: AROYLHYDRAZONES, Pyridines, Population, Hydrazone, Disease, Química Inorgánica y Nuclear, 010402 general chemistry, Ligands, 01 natural sciences, Biochemistry, Proof of Concept Study, Inorganic Chemistry, ZINC(II), 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, ALZHEIMER’S DISEASE, Alzheimer Disease, Coordination Complexes, Pyridine, Lack of efficacy, Moiety, education, Nootropic Agents, chemistry.chemical_classification, Aundefined PEPTIDE, education.field_of_study, Amyloid beta-Peptides, Molecular Structure, Chemistry, Ligand, Aβ peptide, Ciencias Químicas, Hydrazones, Combinatorial chemistry, Peptide Fragments, 0104 chemical sciences, Zinc, MPAC, CIENCIAS NATURALES Y EXACTAS, 030217 neurology & neurosurgery, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47698b2f5d0c15e20f360663e4def793
https://pubmed.ncbi.nlm.nih.gov/30145655

المؤلفون: Christian Griesinger, Markus Zweckstetter, Liliana Quintanar, Marco C. Miotto, Claudio O. Fernández, Mayra D. Pavese

المصدر: Inorganic Chemistry
Inorganic chemistry 56(17), 10387-10395 (2017). doi:10.1021/acs.inorgchem.7b01292

مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, 01 natural sciences, SNCB protein, human, Coordination Complexes, metabolism [Peptide Fragments], metabolism [alpha-Synuclein], Parkinson, chemistry [beta-Synuclein], Protein secondary structure, Parkinson Disease, Acetylation, Bioinorganic chemistry, metabolism [Coordination Complexes], Chemistry, Bioinorganic, visual_art, ddc:540, alpha-Synuclein, visual_art.visual_art_medium, CIENCIAS NATURALES Y EXACTAS, Protein Binding, Otras Ciencias Biológicas, metabolism [Parkinson Disease], chemistry.chemical_element, Motility, 010402 general chemistry, Inorganic Chemistry, Metal, Ciencias Biológicas, 03 medical and health sciences, beta-Synuclein, Humans, SNCA protein, human, Physical and Theoretical Chemistry, Binding site, chemistry [Coordination Complexes], metabolism [Copper], Synuclein, Binding Sites, chemistry [Copper], Copper, Peptide Fragments, 0104 chemical sciences, Crystallography, 030104 developmental biology, chemistry [alpha-Synuclein], chemistry, chemistry [Peptide Fragments], metabolism [beta-Synuclein], Biophysics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfbd45b5e91294a78bfc51ee41c8942
https://pubs.acs.org/doi/10.1021/acs.inorgchem.7b01292

المؤلفون: Carolina Sánchez-López, Andres Binolfi, Jorge M. del Campo, Rodrigo Cortés-Mejía, Claudio O. Fernández, Liliana Quintanar, Marco C. Miotto

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: Circular dichroism, Amyloid, Stereochemistry, BIOINORGANIC, COPPER, Peptide, 010402 general chemistry, 01 natural sciences, law.invention, BIOPHYSICS, Inorganic Chemistry, purl.org/becyt/ford/1 [https], Molecular dynamics, chemistry.chemical_compound, law, purl.org/becyt/ford/1.4 [https], Imidazole, DIABETES, Physical and Theoretical Chemistry, Electron paramagnetic resonance, chemistry.chemical_classification, geography, geography.geographical_feature_category, 010405 organic chemistry, Chemistry, Otras Ciencias Químicas, Ciencias Químicas, Islet, Ligand (biochemistry), 0104 chemical sciences, Biochemistry, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af8a1ed1c5fd2ffb9b7620a08e4b629
https://pubs.acs.org/doi/10.1021/acs.inorgchem.6b01963

المؤلفون: Marco C. Miotto, Ariel A. Valiente-Gabioud, Maria Eugenia Chesta, Verónica A. Lombardo, Andres Binolfi, Claudio O. Fernández

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: 0301 basic medicine, Indoles, Amyloid beta, Otras Ciencias Biológicas, Phthalocyanines, Tau protein, Peptide, Brain damage, Disease, Plasma protein binding, Neurodegenerative, Protein aggregation, Isoindoles, Ciencias Biológicas, purl.org/becyt/ford/1 [https], Aggregation, 03 medical and health sciences, Structure-Activity Relationship, mental disorders, medicine, Structure–activity relationship, Humans, Parkinson, purl.org/becyt/ford/1.6 [https], chemistry.chemical_classification, biology, Proteins, Neurodegenerative Diseases, General Medicine, General Chemistry, nervous system diseases, 030104 developmental biology, Biochemistry, chemistry, Cancer research, biology.protein, medicine.symptom, CIENCIAS NATURALES Y EXACTAS, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37276ec69e6cf93b63275cd0a75a1a5b
https://pubmed.ncbi.nlm.nih.gov/27136297

المؤلفون: Ariel A. Valiente-Gabioud, Markus Zweckstetter, Philipp Selenko, Andres Binolfi, Marco C. Miotto, Giulia Rossetti, Claudio O. Fernández, Christian Griesinger, Paolo Carloni

المصدر: Journal of the American Chemical Society 137(20), 6444-6447 (2015). doi:10.1021/jacs.5b01911
Journal of the American Chemical Society

مصطلحات موضوعية: Protein Folding, Magnetic Resonance Spectroscopy, Stereochemistry, Biochemistry, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, synuclein, chemistry [Organometallic Compounds], Organometallic Compounds, Parkinson, Binding site, skin and connective tissue diseases, Protein secondary structure, Alpha-synuclein, Binding Sites, conformational transition, Molecular Structure, Chemistry, Otras Ciencias Químicas, Ciencias Químicas, food and beverages, Acetylation, General Chemistry, Nuclear magnetic resonance spectroscopy, chemistry [Copper], eye diseases, Folding (chemistry), stomatognathic diseases, chemistry [alpha-Synuclein], ddc:540, Synuclein, alpha-Synuclein, Protein folding, Cu(I), Copper, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea1e23e6758c00649c84f8dfec9579d
https://pubs.acs.org/doi/10.1021/jacs.5b01911

المؤلفون: Jesus Landeira-Fernandez, Daphne S. Cukierman, Nicolás A. Rey, Rachel Ann Hauser-Davis, L. V. de Freitas, Ariel A. Valiente-Gabioud, Claudio O. Fernández, Marco C. Miotto, W. S. Cruz

المصدر: Metallomics : integrated biometal science. 7(5)

مصطلحات موضوعية: Drug, Male, media_common.quotation_subject, In silico, Biophysics, Hydrazone, Pharmacology, Biochemistry, Biomaterials, In vivo, Alzheimer Disease, medicine, Isoniazid, Animals, Homeostasis, Humans, Rats, Wistar, media_common, chemistry.chemical_classification, Amyloid beta-Peptides, Chemistry, Metals and Alloys, Hydrazones, In vitro, Acute toxicity, Peptide Fragments, Zinc, Chemistry (miscellaneous), Blood-Brain Barrier, Copper, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2468d385e1ce7860289f844f41c0a443
https://pubmed.ncbi.nlm.nih.gov/25860559

المؤلفون: Marco C. Miotto, Markus Zweckstetter, Claudio O. Fernández, Christian Griesinger, Andres Binolfi

المصدر: Journal of inorganic biochemistry 141, 208-211 (2014). doi:10.1016/j.jinorgbio.2014.08.012
Journal of Inorganic Biochemistry

مصطلحات موضوعية: ALPHA-SYNUCLEIN, Stereochemistry, chemistry [Recombinant Proteins], Molecular Sequence Data, CU(I), Biochemistry, Protein Structure, Secondary, Inorganic Chemistry, Residue (chemistry), chemistry.chemical_compound, chemistry [Histidine], Imidazole, Humans, Histidine, Protein Interaction Domains and Motifs, Amino Acid Sequence, Binding site, Binding selectivity, Alpha-synuclein, Synucleinopathies, Binding Sites, Otras Ciencias Químicas, Ciencias Químicas, Bioinorganic chemistry, Cations, Monovalent, chemistry [Copper], Affinities, Recombinant Proteins, genetics [Recombinant Proteins], Solutions, Kinetics, chemistry [alpha-Synuclein], chemistry, ddc:540, genetics [alpha-Synuclein], alpha-Synuclein, Thermodynamics, MET-RICH SITES, PARKINSON, Oxidation-Reduction, CIENCIAS NATURALES Y EXACTAS, Copper, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a30527d346fe6fc87c3f288f9cb66d
https://pubmed.ncbi.nlm.nih.gov/25218565

المؤلفون: Christian Griesinger, Liliana Quintanar, Markus Zweckstetter, Claudio O. Fernández, Marco C. Miotto, Esaú E. Rodriguez, Andres Binolfi, Ariel A. Valiente-Gabioud, Valentina Torres-Monserrat

المصدر: Inorganic Chemistry
Inorganic chemistry 53(9), 4350-4358 (2014). doi:10.1021/ic4031377

مصطلحات موضوعية: Parkinson's disease, Stereochemistry, Proton Magnetic Resonance Spectroscopy, Otras Ciencias Biológicas, metabolism [Parkinson Disease], Peptide, Catalysis, Inorganic Chemistry, Oxidative damage, Ciencias Biológicas, Residue (chemistry), medicine, metabolism [alpha-Synuclein], Physical and Theoretical Chemistry, metabolism [Copper], chemistry.chemical_classification, Alfa-Sinucleina, Oxidación, Chemistry, Metal binding, Otras Ciencias Químicas, Ciencias Químicas, Parkinson Disease, Nuclear magnetic resonance spectroscopy, medicine.disease, chemistry [Copper], Cobre, chemistry [alpha-Synuclein], ddc:540, Copper catalyzed, alpha-Synuclein, α synuclein, Oxidation-Reduction, Copper, CIENCIAS NATURALES Y EXACTAS, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a33f7a28f09c6f4bba5bd8a4877dd9
https://hdl.handle.net/11858/00-001M-0000-0019-B6EC-311858/00-001M-0000-0019-B6F6-B11858/00-001M-0000-0019-B6F7-9