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    Design and Synthesis of a Series of Piperazine-1-carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species

    المؤلفون: Joaquín Pastor, Marcel Viellevoye, David Corens, Jan Heeres, Isabelle E.J.A. François, Marcel Borgers, Gerrit D. Dispersyn, Eddy Jean Edgard Freyne, Jannie Ausma, Lieven Meerpoel, Frederik Deroose, Erwin Coesemans, Sonia Martínez González, Klaartje Pellens, Bruno P. A. Cammue, Karin Thevissen, Els M.K. Meert

    المصدر: ChemMedChem. 4:1714-1721

    مصطلحات موضوعية: Antifungal, Antifungal Agents, Stereochemistry, medicine.drug_class, Endogeny, Piperazine-1-carboxamidine, Biochemistry, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, Candida albicans, Drug Discovery, Side chain, medicine, Phenyl group, General Pharmacology, Toxicology and Pharmaceutics, Mode of action, Pharmacology, chemistry.chemical_classification, Reactive oxygen species, biology, Organic Chemistry, biology.organism_classification, chemistry, Drug Design, Molecular Medicine, Reactive Oxygen Species

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b70e951fd39402256c839142f11e00d
    https://doi.org/10.1002/cmdc.200900249

    View record in OpenAIRE

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