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1Academic Journal
المؤلفون: Xin Yu, Merlinda Conyne, Marc R. Lake, Karl A. Walter, Jing Min
المصدر: mAbs, Vol 14, Iss 1 (2022)
مصطلحات موضوعية: Signal peptides, N-terminal miscleavage, antibodies, deep learning, SignalP 5.0, in silico screening, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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2
المؤلفون: Gaurang P Bhide, Natalie E Bohrer, Danying Song, Jeanne Cabel, Marc R Lake, John E Harlan, Laura J Miesbauer
المصدر: Glycobiology.
مصطلحات موضوعية: Biochemistry
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3
المؤلفون: Catherine Zhang, Yoshiko Akamatsu, Alan F. Wahl, Han Kim, Ramesh Iyer, Jeanne M Cabel, Mien Sho, Nicole A. Belmar, Shiming Ye, Patricia Culp, Debra Chao, Marc R. Lake, Siu sze Tan, Cohen Diane Sau Mun, Yuni Fang, Diane Hollenbaugh, Danying Song, Donghee Choi, John Harlan
المصدر: Cancer Immunology Research. 7:1864-1875
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, medicine.drug_class, T-Lymphocytes, Immunology, Antigen-Presenting Cells, GPI-Linked Proteins, Lymphocyte Activation, Monoclonal antibody, Mice, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Antigen, Antigens, Neoplasm, Cell Line, Tumor, Antibodies, Bispecific, medicine, Animals, Humans, Mesothelin, CD40 Antigens, Mice, Inbred BALB C, CD40, biology, Chemistry, Neoplasms, Experimental, Mice, Mutant Strains, Tumor antigen, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, Toxicity, biology.protein, Cancer research, Antibody
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4
المؤلفون: Ramesh Iyer, Ramkrishna Sadhukhan, Amy Greischar, Rui Wang, Jennifer Hardman, Denise C. Perron, B. Sielaff, Maria A. Argiriadi, Ievgeniia Dubrovska, Russell A. Judge, John Harlan, David A. Egan, Lei Gao, Marc R. Lake, Bradford L. McRae, Lorenzo Benatuil, Silvino Sousa
المصدر: BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-13 (2019)
BMC Molecular and Cell Biologyمصطلحات موضوعية: Models, Molecular, Agonist, medicine.drug_class, Static Electricity, Antigen-Antibody Complex, Epitope, Proinflammatory cytokine, Immunoglobulin Fab Fragments, medicine, CD40, Humans, CD40 Antigens, lcsh:QH573-671, Receptor, Molecular Biology, Antibody, biology, Chemistry, lcsh:Cytology, Crystal structure, Antagonist, Antibodies, Monoclonal, hemic and immune systems, Cell Biology, T helper cell, Cell biology, HEK293 Cells, medicine.anatomical_structure, biology.protein, Signal Transduction, Research Article
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5
المؤلفون: Leyu Wang, Viktor Todorović, Ramkrishna Sadhukhan, C. Gerstein, Anil Vasudevan, Henning Stöckmann, Violeta L. Marin, Victoria E. Scott, Marc R. Lake, Paul L. Richardson
المصدر: Journal of the American Chemical Society. 139(46)
مصطلحات موضوعية: 0301 basic medicine, Glycan, Cell Survival, Chemical biology, Receptors, Cell Surface, GPI-Linked Proteins, Ligands, Biochemistry, Catalysis, 03 medical and health sciences, Colloid and Surface Chemistry, Polysaccharides, Fluorescence Resonance Energy Transfer, Humans, Receptors, Histamine H3, Receptor, Terbium, biology, Drug discovery, Chemistry, Folate Receptors, GPI-Anchored, General Chemistry, Receptors, Interleukin, Transmembrane protein, 030104 developmental biology, Förster resonance energy transfer, biology.protein, Antibody, Cytokine receptor
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6
المؤلفون: Marc R. Lake, Alla Korepanova, Andrew M. Petros, Richard F. Clark, Steve D. Pratt, Sanjay C. Panchal, Diana Raich, Sujatha M. Gopalakrishnan, Chaohong Sun, Kenton L. Longenecker
المصدر: Bioorganicmedicinal chemistry letters. 28(3)
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Computational biology, Biochemistry, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Piperidines, Drug Discovery, Fluorescence Resonance Energy Transfer, Humans, Enzyme Inhibitors, Nicotinamide Phosphoribosyltransferase, Molecular Biology, Acrylamides, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Molecular Docking Simulation, 030104 developmental biology, Docking (molecular), 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Cytokines, Protein A
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7
المؤلفون: Alex R. Shoemaker, Uri S. Ladror, Jun Guo, Gail Bukofzer, Marc R. Lake, Ramesh Iyer, Cherrie K. Donawho, Tanushree Samanta, Xin Lu, Yu Xiao, Tzu-Hsuan Huang, Medha J. Tomlinson, John Harlan
المصدر: PLoS ONE, Vol 14, Iss 8, p e0219829 (2019)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Antibodies, Neoplasm, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Cancer Treatment, CD8-Positive T-Lymphocytes, Biochemistry, Cell Fusion, Major Histocompatibility Complex, White Blood Cells, Mice, 0302 clinical medicine, Cancer immunotherapy, Animal Cells, Neoplasms, Medicine and Health Sciences, Tumor Microenvironment, Cytotoxic T cell, Enzyme-Linked Immunoassays, Multidisciplinary, biology, T Cells, Chemistry, Animal Models, Tumor antigen, medicine.anatomical_structure, Oncology, Experimental Organism Systems, 030220 oncology & carcinogenesis, Medicine, Female, Immunotherapy, Cellular Types, Research Article, Cell Physiology, Immune Cells, Science, T cell, Immunology, Cytotoxic T cells, Mouse Models, Mice, Inbred Strains, Research and Analysis Methods, 03 medical and health sciences, Model Organisms, Antigen, Antigens, Neoplasm, Cell Line, Tumor, MHC class I, medicine, Animals, Humans, Immunoassays, Tumor microenvironment, Blood Cells, Biology and Life Sciences, Proteins, Interferon-alpha, Cell Biology, Chemokine CXCL10, HEK293 Cells, 030104 developmental biology, Immunologic Techniques, Animal Studies, biology.protein, Cancer research, Clinical Immunology, Interferons, Clinical Medicine, CD8
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8
المؤلفون: Steve Kakavas, Kathy M. Krueger, Ana Pereda-Lopez, Timothy A. Esbenshade, Brian R. Estvander, Marc R. Lake, Mark L. Chiu
المصدر: Production of Membrane Proteins: Strategies for Expression and Isolation
مصطلحات موضوعية: Insect cell, Chemistry, Heterologous, Histamine H3 receptor, Cell biology, G protein-coupled receptor
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9
المؤلفون: Jun Guo, Cherrie K. Donawho, Uri S. Ladror, Tzu-Hsuan Huang, Gail Bukofzer, Medha J. Tomlinson, Alexander R. Shoemaker, Xin Lu, Yu Xiao, Bill Pappano, Ramesh B. Lyer, Marc R. Lake, John Harlan
المصدر: Cancer Research. 78:2783-2783
مصطلحات موضوعية: Cancer Research, Tumor microenvironment, biology, Effector, medicine.medical_treatment, T cell, Immune system, medicine.anatomical_structure, Oncology, Cancer immunotherapy, Antigen, MHC class I, biology.protein, medicine, Cancer research, Cytotoxic T cell
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10
المؤلفون: Paul L. Richardson, Victoria E. Scott, Marie E. Uchic, Larry Solomon, Edward T. Olejniczak, Karl A. Walter, Rachel Davis-Taber, Danying Song, Chaohong Sun, Leo W. Barrett, Ana Pereda-Lopez, Philip J. Hajduk, Marc R. Lake
المصدر: Proceedings of the National Academy of Sciences. 104:7875-7880
مصطلحات موضوعية: Molecular Sequence Data, Vasoactive intestinal peptide, Peptide binding, Peptide, Biology, Receptors, Corticotropin-Releasing Hormone, Protein Structure, Secondary, Mice, Extracellular, Animals, Humans, Amino Acid Sequence, Receptor, Peptide sequence, chemistry.chemical_classification, Multidisciplinary, C-terminus, Biological Sciences, Protein Structure, Tertiary, Cell biology, Solutions, N-terminus, Biochemistry, chemistry, Mutation, Pituitary Adenylate Cyclase-Activating Polypeptide, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I
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11
المؤلفون: Wende Niforatos, Karl A. Walter, Marc R. Lake, Thomas F. Holzman, Jun Chen, Victoria E. Scott, Xu-Feng Zhang, Robert B. Moreland, Connie R. Faltynek, Torben R. Neelands
المصدر: Molecular Pharmacology. 71:1209-1216
مصطلحات موضوعية: Ankyrins, Male, TRPV4, Population, TRPV1, Gene Expression, TRPM Cation Channels, TRPV Cation Channels, Nerve Tissue Proteins, Pharmacology, Transfection, Amidohydrolases, Rats, Sprague-Dawley, chemistry.chemical_compound, Transient receptor potential channel, Transient Receptor Potential Channels, Fatty acid amide hydrolase, Ganglia, Spinal, Animals, Humans, education, TRPA1 Cation Channel, Ion channel, TRPC Cation Channels, Neurons, education.field_of_study, Cell Membrane, food and beverages, Anandamide, URB597, Rats, chemistry, Biochemistry, Benzamides, Molecular Medicine, Calcium Channels, Carbamates, Ion Channel Gating, psychological phenomena and processes
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12
المؤلفون: Steven Cassar, Karl A. Walter, Jing Xu, Jun Chen, Reza S. Sabet, Connie R. Faltynek, Steve D. Pratt, Robert B. Moreland, Victoria E. Scott, Usha Warrior, Sujatha M. Gopalakrishnan, Marc R. Lake, Ana Pereda-Lopez, Thomas F. Holzman, Murali Gopalakrishnan, Wende Niforatos
المصدر: SLAS Discovery. 12:61-69
مصطلحات موضوعية: High-throughput screening, Cell, Nerve Tissue Proteins, Biology, Transfection, Biochemistry, Fluorescence, Analytical Chemistry, Chemical library, Transient receptor potential channel, chemistry.chemical_compound, Transient Receptor Potential Channels, Membrane Transport Modulators, Freezing, medicine, Humans, TRPA1 Cation Channel, Voltage-dependent calcium channel, Molecular biology, Clone Cells, Cell biology, Electrophysiology, medicine.anatomical_structure, chemistry, Cell culture, Molecular Medicine, Calcium, Calcium Channels, Biotechnology
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13
المؤلفون: Cynthia L. Williamson, Marc R. Lake, Robert D. Slocum
المصدر: Plant Physiology and Biochemistry. 36:555-562
مصطلحات موضوعية: UDP-glucose 4-epimerase, Physiology, Plant Science, Biology, Molecular cloning, biology.organism_classification, Pisum, carbohydrates (lipids), Open reading frame, Biochemistry, Complementary DNA, Gene expression, Genetics, Mucigel, Gene
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14
المؤلفون: Jun Chen, Dawon Kang, Karl Walter, Betty Yao, Jing Xu, Marc R. Lake, Donghee Kim, Chaohong Sun, James O. Hogan
المصدر: Nature Communications
مصطلحات موضوعية: Patch-Clamp Techniques, Rodent, Molecular Sequence Data, General Physics and Astronomy, Differential Threshold, Nerve Tissue Proteins, Gating, General Biochemistry, Genetics and Molecular Biology, Article, Mice, Transient Receptor Potential Channels, Species Specificity, Isothiocyanates, biology.animal, Evoked Potentials, Somatosensory, medicine, Animals, Humans, Amino Acid Sequence, Receptor, TRPA1 Cation Channel, Ion channel, TRPC Cation Channels, Multidisciplinary, biology, Sequence Homology, Amino Acid, Lizard, food and beverages, General Chemistry, Olfactory Perception, Macaca mulatta, Cell biology, Protein Structure, Tertiary, Rats, Cold Temperature, Transmembrane domain, Menthol, Biochemistry, Amino Acid Substitution, Cold sensitivity, Calcium Channels, medicine.symptom, Ion Channel Gating, psychological phenomena and processes
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15
المؤلفون: Rohinton Edalji, Amy Greischar, Clarissa G. Jakob, Enrico L. Digiammarino, Uri S. Ladror, Karl A. Walter, Charles W. Hutchins, John E. Harlan, Tariq Ghayur, Liu Junjian, Marc R. Lake
المصدر: mAbs. 3(5)
مصطلحات موضوعية: Stereochemistry, Chemistry, Tumor Necrosis Factor-alpha, Immunology, Molecular Sequence Data, Immunoglobulin Variable Region, Antibodies, Monoclonal, Protein engineering, Plasma protein binding, Immunoglobulin domain, Ligands, Protein Engineering, Domain (software engineering), Protein Structure, Tertiary, Kinetics, Protein structure, Drug Design, Report, Immunology and Allergy, Humans, Amino Acid Sequence, Linker, Binding selectivity, Binding domain, Protein Binding
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16
المؤلفون: Robert B. Moreland, Alla Korepanova, Connie R. Faltynek, Marc R. Lake, Ana Pereda-Lopez, Bruce R. Bianchi, Ping Han, Melissa H. Vos, Mark L. Chiu
المصدر: Journal of neuroscience methods. 200(2)
مصطلحات موضوعية: Immunoprecipitation, medicine.drug_class, TRPV Cation Channels, Enzyme-Linked Immunosorbent Assay, Monoclonal antibody, Transfection, Tritium, Epitope, Affinity chromatography, Ganglia, Spinal, Protein purification, Protein A/G, medicine, Animals, Humans, Urea, Hybridomas, biology, Dose-Response Relationship, Drug, Immunodominant Epitopes, musculoskeletal, neural, and ocular physiology, General Neuroscience, Antibodies, Monoclonal, Isoquinolines, Molecular biology, Rats, HEK293 Cells, nervous system, Biochemistry, Gene Expression Regulation, Spinal Cord, biology.protein, lipids (amino acids, peptides, and proteins), Antibody, psychological phenomena and processes, Myc-tag, Protein Binding
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17
المؤلفون: Jun, Chen, Sujatha, Gopalakrishnan, Marc R, Lake, Bruce R, Bianchi, John, Locklear, Regina M, Reilly
المصدر: Methods in enzymology. 485
مصطلحات موضوعية: Cryopreservation, Electrophysiology, Drug Evaluation, Preclinical, Fluorescence Resonance Energy Transfer, Animals, Humans, Calcium, Transfection, Ion Channels, Cell Line, Receptors, G-Protein-Coupled
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18
المؤلفون: John Locklear, Bruce R. Bianchi, Regina M. Reilly, Sujatha M. Gopalakrishnan, Marc R. Lake, Jun Chen
مصطلحات موضوعية: medicine.anatomical_structure, Drug discovery, Cell culture, Cell, medicine, Biology, Transient transfection, Receptor, Ion channel, Cell biology, Cell based, G protein-coupled receptor
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19
المؤلفون: Marc R. Lake, Robert D. Slocum, Cynthia L. Williamson
المصدر: Plant molecular biology. 31(6)
مصطلحات موضوعية: DNA, Complementary, Immunoprecipitation, Molecular Sequence Data, Plant Science, Biology, Cross Reactions, Polymerase Chain Reaction, Homology (biology), Mice, Complementary DNA, Genetics, Animals, Tissue Distribution, Northern blot, Amino Acid Sequence, RNA, Messenger, Protein Precursors, Gene, Ornithine Carbamoyltransferase, Southern blot, DNA Primers, Gene Library, chemistry.chemical_classification, Molecular mass, Sequence Homology, Amino Acid, Peas, food and beverages, General Medicine, Molecular biology, Precipitin Tests, Amino acid, chemistry, Biochemistry, RNA, Plant, Agronomy and Crop Science, Genome, Plant
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20
المؤلفون: Michael G. Fickes, Xiaofeng Li, Thomas W. von Geldern, Heidi Wells, Kent D. Stewart, Thomas H. Lubben, Rohinton Edalji, Amanda K Mika, Daisy Pireh, Lakshmi Bhagavatula, Paul E. Wiedeman, James M. Trevillyan, Stephen J. Ballaron, Anita J Kempf-Grote, Elizabeth H. Fry, Hing L. Sham, David Madar, Michael A. Stashko, Zhonghua Pei, David W A Beno, Bradley A. Zinker, Marc R. Lake, Kenton L. Longenecker, Michelle A. Long, Todd S. McDermott, Larry R. Solomon
المصدر: Journal of Medicinal Chemistry. 49:5387-5387
مصطلحات موضوعية: Blood Glucose, Models, Molecular, Pyrrolidines, Stereochemistry, Dipeptidyl Peptidase 4, Crystallography, X-Ray, Chemical synthesis, Dipeptidyl peptidase, Rats, Sprague-Dawley, Serine, Structure-Activity Relationship, Drug Stability, Catalytic Domain, Nitriles, Hydrolase, Drug Discovery, Animals, Humans, Hypoglycemic Agents, Structure–activity relationship, Protease Inhibitors, Dipeptidyl peptidase-4, chemistry.chemical_classification, biology, Chemistry, Stereoisomerism, Glucose Tolerance Test, Rats, Rats, Zucker, Enzyme, Biochemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Anti-Obesity Agents
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