المؤلفون: Manuela Marabita, Martina Baraldo, Francesca Solagna, Judith Johanna Maria Ceelen, Roberta Sartori, Hendrik Nolte, Ivan Nemazanyy, Stéphane Pyronnet, Marcus Kruger, Mario Pende, Bert Blaauw

المصدر: Cell Reports, Vol 17, Iss 2, Pp 501-513 (2016)

مصطلحات موضوعية: skeletal muscle, hypertrophy, AKT, S6K1, rapamycin, p62, protein aggregates, muscle force, mTOR, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716312426; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/f4d1853c52474c59a39136e91c83f117

المؤلفون: Libero Vitiello, Manuela Marabita, Elisa Sorato, Leonardo Nogara, Giada Forestan, Vincent Mouly, Leonardo Salviati, Manuel Acosta, Bert Blaauw, Marcella Canton

المصدر: Frontiers in Physiology, Vol 9 (2018)

مصطلحات موضوعية: muscular dystrophy, mitochondrial ROS, monoamine oxidase, oxidative stress, safinamide, DMD, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2018.01087/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/9b8ea976cfdd4266bdbc2e2115864bf0

المؤلفون: Marcelo G. Pereira, Kenneth A. Dyar, Leonardo Nogara, Francesca Solagna, Manuela Marabita, Martina Baraldo, Francesco Chemello, Elena Germinario, Vanina Romanello, Hendrik Nolte, Bert Blaauw

المصدر: Frontiers in Physiology, Vol 8 (2017)

مصطلحات موضوعية: mTORC1, skeletal muscle, hypertrophy, ribosome biogenesis, immediate early genes, overload, Physiology, QP1-981

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fphys.2017.00968/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/3fac33da69a24111a4d639bbbfaff226

المؤلفون: Leonardo Nogara, Saskia Lassche, Jonne Doorduin, Norma B. Romero, Benno Küsters, Tamar E. Sztal, Baziel G.M. van Engelen, Balázs Kiss, Stefan Conijn, Josine M. de Winter, Coen A.C. Ottenheijm, Weikang Ma, Georg Ramm, Viola Oorschot, Joery P. Molenaar, Shengyi Shen, Christopher N. Johnson, Richard J. Rodenburg, Bert Blaauw, Robbert van der Pijl, Henk Granzier, Thomas E. Hall, Ken Campbell, Frank Li, Thomas C. Irving, Alan H. Beggs, Michaela Yuen, Reinier A. Boon, Manuela Marabita, Menne van Willigenburg, Esmee S.B. Van Kleef, Noelia Lozano-Vidal, Sylvia J. P. Bogaards, Robert J. Bryson-Richardson, Avnika A. Ruparelia, Dilson E. Rassier, Martijn van de Locht, Edoardo Malfatti, Malin Persson, Zherui Xiong, Nicol C. Voermans

المساهمون: Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologies appliquées (END-ICAP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), VIDI 016.126.319 645648, H2020-MSCA-RISE-2014 W.OR17-08 National Institutes of Health, NIH: R01 HD075802 U.S. Department of Energy, USDOE National Institute of General Medical Sciences, NIGMS: 1S10OD018090-01 National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIAMS: HL133359, R01 AR053897 National Institute of Child Health and Human Development, NICHD Muscular Dystrophy Association, MDA: MDA602235 Office of Science, SC Argonne National Laboratory, ANL: 9 P41 GM103622 Advanced Photon Sciences, APS: DE-AC02-06CH11357 National Health and Medical Research Council, NHMRC: APP1121651 Vetenskapsrådet, VR: 2015-00385, This work was supported by the Dutch Foundation for Scientific Research (VIDI 016.126.319 to CACO), the Princess Beatrix Muscle Foundation (W.OR17-08 to CACO, NCV, and BGMVE), H2020-MSCA-RISE-2014 (645648 Muscle Stress Relief to CACO), the Advanced Photon Source (DE-AC02-06CH11357), A Foundation Building Strength for Nemaline Myopathy (to CACO), the National Health and Medical Research Council (NHMRC) Early Career Fellowship (APP1121651 to MY), the National Institute of Child Health and Human Development (NIH R01 HD075802 to AHB), the Muscular Dystrophy Association (USA) (MDA602235 to AHB), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH R01 AR053897 to HG), the NIH (HL133359 to KC). This research used resources of the Advanced Photon Source, a U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under contract no. DE-AC02-06CH11357. This project was supported by grant 9 P41 GM103622 from the National Institute of General Medical Sciences of the NIH. Use of the Pilatus 3 1M detector was provided by grant 1S10OD018090-01 from the National Institute of General Medical Sciences. The content is solely the responsibility of the authors and does not necessarily reflect the official views of the National Institute of General Medical Sciences or the NIH. MP was funded by a postdoctoral grant from the Swedish Research Council (2015-00385)., Physiology, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation, ACS - Atherosclerosis & ischemic syndromes, ACS - Heart failure & arrhythmias, Academic Medical Center

المصدر: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, 130 (2), pp.754-767. ⟨10.1172/JCI124000⟩
Journal of Clinical Investigation, 130, 2, pp. 754-767
J Clin Invest
Journal of Clinical Investigation, 130(2), 754-767. The American Society for Clinical Investigation
de Winter, J M, Molenaar, J P, Yuen, M, van der Pijl, R, Shen, S, Conijn, S, van de Locht, M, Willigenburg, M, Bogaards, S J P, van Kleef, E S, Lassche, S, Persson, M, Rassier, D E, Sztal, T E, Ruparelia, A A, Oorschot, V, Ramm, G, Hall, T E, Xiong, Z, Johnson, C N, Li, F, Kiss, B, Lozano-Vidal, N, Boon, R A, Marabita, M, Nogara, L, Blaauw, B, Rodenburg, R J, Küsters, B, Doorduin, J, Beggs, A H, Granzier, H, Campbell, K, Ma, W, Irving, T, Malfatti, E, Romero, N B, Bryson-Richardson, R J, van Engelen, B G M, Voermans, N C & Ottenheijm, C A C 2020, ' KBTBD13 is an actin-binding protein that modulates muscle kinetics ', Journal of Clinical Investigation, vol. 130, no. 2, pp. 754-767 . https://doi.org/10.1172/JCI124000
Journal of clinical investigation, 130(2), 754-767. The American Society for Clinical Investigation
Journal of Clinical Investigation, 130, 754-767

مصطلحات موضوعية: 0301 basic medicine, Sarcomeres, Muscle Relaxation, [SDV]Life Sciences [q-bio], Kinetics, Muscle Proteins, Skeletal muscle, Myopathies, Nemaline, Contractility, 03 medical and health sciences, Mice, 0302 clinical medicine, Nemaline myopathy, All institutes and research themes of the Radboud University Medical Center, medicine, Animals, Humans, Actin-binding protein, Actin, Zebrafish, Mice, Knockout, biology, Relaxation (psychology), Chemistry, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], General Medicine, Zebrafish Proteins, Neuromuscular disease, medicine.disease, Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], 030104 developmental biology, medicine.anatomical_structure, Muscle relaxation, 030220 oncology & carcinogenesis, Biophysics, biology.protein, Commentary, Genetic diseases, Muscle Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8814b2daabcdfb84373f75468712d908
http://hdl.handle.net/11577/3321703

المؤلفون: Libero Vitiello, Manuela Marabita, Elisa Sorato, Leonardo Nogara, Giada Forestan, Vincent Mouly, Leonardo Salviati, Manuel Acosta, Bert Blaauw, Marcella Canton

مصطلحات موضوعية: Physiology, Exercise Physiology, Nutritional Physiology, Reproduction, Cell Physiology, Systems Physiology, Animal Physiology - Biophysics, Animal Physiology - Cell, Animal Physiology - Systems, Comparative Physiology, Physiology not elsewhere classified, muscular dystrophy, mitochondrial ROS, monoamine oxidase, oxidative stress, safinamide, DMD, mdx

Relation: https://figshare.com/articles/figure/Image_1_Drug_Repurposing_for_Duchenne_Muscular_Dystrophy_The_Monoamine_Oxidase_B_Inhibitor_Safinamide_Ameliorates_the_Pathological_Phenotype_in_mdx_Mice_and_in_Myogenic_Cultures_From_DMD_Patients_JPEG/6964739

الاتاحة: https://doi.org/10.3389/fphys.2018.01087.s001
https://figshare.com/articles/figure/Image_1_Drug_Repurposing_for_Duchenne_Muscular_Dystrophy_The_Monoamine_Oxidase_B_Inhibitor_Safinamide_Ameliorates_the_Pathological_Phenotype_in_mdx_Mice_and_in_Myogenic_Cultures_From_DMD_Patients_JPEG/6964739

المؤلفون: Mario Pende, Bert Blaauw, Judith Johanna Maria Ceelen, Marcus Krüger, Ivan Nemazanyy, Stéphane Pyronnet, Roberta Sartori, Hendrik Nolte, Francesca Solagna, Martina Baraldo, Manuela Marabita

المصدر: Cell Reports, Vol 17, Iss 2, Pp 501-513 (2016)

مصطلحات موضوعية: 0301 basic medicine, Genetics and Molecular Biology (all), Sarcopenia, Ribosome biogenesis, Cell Cycle Proteins, Biochemistry, Muscle hypertrophy, Mice, 0302 clinical medicine, Eukaryotic Initiation Factors, Phosphorylation, lcsh:QH301-705.5, Mice, Knockout, Kinase, TOR Serine-Threonine Kinases, p62, Ribosomal Protein S6 Kinases, 70-kDa, S6K1, protein aggregates, Oncogene Protein v-akt, AKT, hypertrophy, mTOR, muscle force, rapamycin, skeletal muscle, Biochemistry, Genetics and Molecular Biology (all), medicine.anatomical_structure, Signal Transduction, medicine.medical_specialty, P70-S6 Kinase 1, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Muscle, Skeletal, Protein kinase B, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Sirolimus, Skeletal muscle, medicine.disease, Phosphoproteins, 030104 developmental biology, Endocrinology, lcsh:Biology (General), Carrier Proteins, Peptides, Ribosomes, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598cdd289c9f45a08822060c80b6c970
http://hdl.handle.net/11577/3221963

المؤلفون: Pamela Gatto, Andrew P. Lieberman, Sibilla Molon, Sara Parodi, Diane M. Robins, Anna Urciuolo, Doriana Borgia, Vanina Romanello, Valeria Morbidoni, Carmelo Milioto, Bert Blaauw, Matteo Pellegrini, Maria Pennuto, Gianni Sorarù, Anna Rocchi, Paolo Bonaldo, Manuela Marabita, Marco Sandri, Andrea Armirotti, Fabio Sambataro, Lodovica Vergani

المصدر: Acta Neuropathologica

مصطلحات موضوعية: 0301 basic medicine, Male, Skeletal muscle, Spinal and bulbar muscular atrophy, Random Allocation, 0302 clinical medicine, Membrane Potential, Mitochondrial, biology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, TOR Serine-Threonine Kinases, Medicine (all), Polyglutamine tract, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Muscle atrophy, Muscular Disorders, Atrophic, 3. Good health, Androgen receptor, medicine.anatomical_structure, High-fat diet, Receptors, Androgen, Disease Progression, mTOR, Female, medicine.symptom, Glycolysis, Oxidation-Reduction, Signal Transduction, medicine.medical_specialty, Clinical Neurology, Mice, Transgenic, Diet, High-Fat, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Atrophy, Internal medicine, PGC1α, medicine, Animals, Humans, Rapamycin, Muscle, Skeletal, Mechanistic target of rapamycin, Original Paper, Lipid metabolism, medicine.disease, Lipid Metabolism, 2734, Neurology (clinical), Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, TFEB, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e8bf4dad00c270d9cc089213414a34
http://hdl.handle.net/11577/3204883

المؤلفون: Mirella Trinei, Valentina Scattolini, Manuela Marabita, Nicol Poncina, Andrea Danesi, Mattia Albiero, Mirto Foletto, Lisa Menegazzo, Elisa Pagnin, Angelo Avogaro, Gian Paolo Fadini, Donato Nitti, Bert Blaauw, Marco Giorgio, Stefano Ciciliot, Luca Prevedello

مصطلحات موضوعية: Blood Glucose, Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Adipose tissue, Apoptosis, medicine.disease_cause, Mice, Endocrinology, Adipocytes, 80 and over, Insulin, Adiposity, Aged, 80 and over, Mice, Knockout, Diabesity, Middle Aged, Diabetes and Metabolism, Adipose Tissue, Adipogenesis, Female, medicine.symptom, Adult, medicine.medical_specialty, Src Homology 2 Domain-Containing, Transforming Protein 1, Knockout, Longevity, Inflammation, Carbohydrate metabolism, Biology, Diet, High-Fat, Insulin resistance, Internal medicine, medicine, Internal Medicine, Animals, Humans, Obesity, Aged, medicine.disease, Diet, High-Fat, Oxidative Stress, Oxidative stress, Insulin Resistance, Shc Signaling Adaptor Proteins, Immunology, Metabolic syndrome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fa035c745388dee2b0b45bd2b1ba4f
http://hdl.handle.net/11577/3191463