المؤلفون: Ahmed Mamai (2415982), Anh M. Chau (14405127), Brian J. Wilson (9305765), Iain D. Watson (14405130), Babu B. Joseph (14405133), Pandiaraju R. Subramanian (14405136), Monzur M. Morshed (14405139), Justin A. Morin (14405142), Michael A. Prakesh (14405145), Tianbao Lu (2457745), Pete Connolly (11173842), Douglas A. Kuntz (141682), Neil C. Pomroy (14405148), Gennady Poda (1479109), Kong Nguyen (2175390), Richard Marcellus (2554267), Graig Strathdee (14405151), Brigitte Theriault (14405154), Ratheesh Subramaniam (11171231), Mohammed Mohammed (1504360), Ayome Abibi (1463617), Manuel Chan (14405157), Jeffrey Winston (14405160), Taira Kiyota (2507788), Elijus Undzys (1428775), Ahmed Aman (3040245), Nigel Austin (1367736), Marc Du Jardin (14405163), Kathryn Packman (93334), Ulrike Phillippar (14405166), Riccardo Attar (14405169), James Edwards (339808), Jeff O’Meara (1942066), David E. Uehling (430111), Rima Al-awar (1884955), Gilbert G. Privé (2617657), Methvin B. Isaac (3040443)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Plant Biology, Chemical Sciences not elsewhere classified, virtual screen hit, high micromolar range, orally bioavailable candidate, diffuse large b, 58 , testing bcl6 inhibition, identify bcl6 inhibitors, oicr12694 / jnj, lead candidate, bcl6 inhibitor, bcl6 ), several forms, repressor binding, optimization resulted, nhl ), hodgkin lymphoma, guided methods

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_OICR12694_A_Novel_Potent_Selective_and_Orally_Biovailable_BCL6_BTB_Inhibitor/21879429

الاتاحة: https://doi.org/10.1021/acsmedchemlett.2c00502.s001