يعرض 1 - 16 نتائج من 16 نتيجة بحث عن '"Manjushree Anjanappa (5168201)"', وقت الاستعلام: 0.36s تنقيح النتائج
  1. 1
    Academic Journal
    Release of Cytochrome C fractions from mitochondria to cytoplasm in MDA-MB-231 TNBC cells upon treatment by AMP-001 and AMP-002 alone and in combination with doxorubicin.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/journal_contribution/Release_of_Cytochrome_C_fractions_from_mitochondria_to_cytoplasm_in_MDA-MB-231_TNBC_cells_upon_treatment_by_AMP-001_and_AMP-002_alone_and_in_combination_with_doxorubicin_/13769956

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.s003

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  2. 2
    Academic Journal
    Cell death quantification by AMP-001 (100 mM) in normal breast epithelial cells (MCF-10A) and in induced pluripotent stem cells (iPS) cardiomyocytes using PI and annexin staining.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/journal_contribution/Cell_death_quantification_by_AMP-001_100_mM_in_normal_breast_epithelial_cells_MCF-10A_and_in_induced_pluripotent_stem_cells_iPS_cardiomyocytes_using_PI_and_annexin_staining_/13769950

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.s001

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  3. 3
    Academic Journal
    S1 File -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/journal_contribution/S1_File_-/13769965

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.s005

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  4. 4
    Image
    Lysosomal instability evidenced by release of acridine orange in AMP-001/002 treated (30 mM) TNBC MDA-MB-231 and in PC3 cells.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Lysosomal_instability_evidenced_by_release_of_acridine_orange_in_AMP-001_002_treated_30_mM_TNBC_MDA-MB-231_and_in_PC3_cells_/13769977

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g004

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  5. 5
    Image
    Fig 1 -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Fig_1_-/13769971

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g002

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  6. 6
    Image
    Fig 5 -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Fig_5_-/13769983

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g006

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  7. 7
    Image
    Fig 2 -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Fig_2_-/13769974

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g003

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  8. 8
    Image
    Treatment of CSC enriched cells with AMP-001 negatively affects cancer stem cell activity and reduces mammosphers (precursor for self-renewal of CSCs) compared to control in vitro .

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Treatment_of_CSC_enriched_cells_with_AMP-001_negatively_affects_cancer_stem_cell_activity_and_reduces_mammosphers_precursor_for_self-renewal_of_CSCs_compared_to_control_i_in_vitro_i_/13769989

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g007

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  9. 9
    Image
    “Treatment with AMP-001/002 causes release of mitochondrial AIF-1 (Mito) into the cytoplasm (Cyto)”.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/_Treatment_with_AMP-001_002_causes_release_of_mitochondrial_AIF-1_Mito_into_the_cytoplasm_Cyto_/13769980

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g005

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  10. 10
    Image
    AMP-001 monotherapy treatment in TNBC mouse model results in reduced tumor growth and size.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/AMP-001_monotherapy_treatment_in_TNBC_mouse_model_results_in_reduced_tumor_growth_and_size_/13770001

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g011

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  11. 11
    Image
    Fig 8 -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Fig_8_-/13769995

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g009

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  12. 12
    Relative average IC-50 values (N = 4, p < 0.05) for AMP-001, AMP-002, AMP-003 in various cancer cells alone or in combination with doxorubicin or with paclitaxel. TNBC cells: MDA-MB-231, 4T1, Breast cancer cells: MCF-7, Gastric cancer cells: MGC-803, SGC-7901, Lung cancer cells: A549, Normal breast epithelial cells: MCF-10A, & induced pluripotent stem cells (iPSC cardiomyocytes). Cells were subjected to 0.1 μM –100 μM dose to calculate IC-50 values using MTT assays.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/dataset/Relative_average_IC-50_values_N_4_p_0_05_for_AMP-001_AMP-002_AMP-003_in_various_cancer_cells_alone_or_in_combination_with_doxorubicin_or_with_paclitaxel_TNBC_cells_MDA-MB-231_4T1_Breast_cancer_cells_MCF-7_Gastric_cancer_cells_MGC-803_SGC-79/13770004

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.t001

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  13. 13
    Image
    Fig 7 -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Fig_7_-/13769992

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g008

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  14. 14
    Image
    Fig 9 -

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/figure/Fig_9_-/13769998

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.g010

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  15. 15
    Selective uptake of AMP-001, AMP-002 and AMP-003 in cathepsin B positive cancer cells MDA-MB-231 cells versus low cathepsin B normal cells MCF-10A (n = 5, p < 0.06).

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/dataset/Selective_uptake_of_AMP-001_AMP-002_and_AMP-003_in_cathepsin_B_positive_cancer_cells_MDA-MB-231_cells_versus_low_cathepsin_B_normal_cells_MCF-10A_n_5_p_0_06_/13770007

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.t002

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  16. 16
    Combination index values for AMP-001.

    المؤلفون: Raghu S. Pandurangi (10114129), Marco Tomasetti (293754), Sekar T. Verapazham (10114132), Ramasamy Paulmurugan (443835), Cynthia Ma (4609264), Sandeep Rajput (4745214), Manjushree Anjanappa (5168201), Harikrishna Nakshatri (3548630)

    مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, AMP -001 acts, PARP, cancer treatment Cancer cells, cancer cells, CRC, MDA-MB, PC, CSC, bulk cancer cells, cell death pathways, AAAPT, survival pathways, Vitamin E analogue, IC

    Relation: https://figshare.com/articles/dataset/Combination_index_values_for_AMP-001_/13770013

    الاتاحة: https://doi.org/10.1371/journal.pone.0225869.t003

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