المؤلفون: Samya S. Alenezi, Manal J. Natto, John O. Igoli, Alexander I. Gray, James Fearnley, Hugo Fearnley, Harry P. de Koning, David G. Watson

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 201-207 (2020)

مصطلحات موضوعية: Trypanosomiasis, Flavanones, Tanzania, Zambia, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320720300427; https://doaj.org/toc/2211-3207

URL الوصول: https://doaj.org/article/7fdd93600ced42479704d0c14f4e3b2a

المؤلفون: Samya S. Alenezi, Naif D. Alenezi, Godwin U. Ebiloma, Manal J. Natto, Marzuq A. Ungogo, John O. Igoli, Valerie A. Ferro, Alexander I. Gray, James Fearnley, Harry P. de Koning, David G. Watson

المصدر: Molecules, Vol 28, Iss 2, p 622 (2023)

مصطلحات موضوعية: red Nigerian propolis, isoflavonoids, Trypanosoma brucei, Trypanosoma congolense, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/2/622; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/4e50d5735c9a4b678a2025f635e82c59

المؤلفون: John B. Nvau, Samya Alenezi, Marzuq A. Ungogo, Ibrahim A. M. Alfayez, Manal J. Natto, Alexander I. Gray, Valerie A. Ferro, Dave G. Watson, Harry P. de Koning, John O. Igoli

المصدر: Frontiers in Chemistry, Vol 8 (2020)

مصطلحات موضوعية: diterpene, trypanosomiasis, leishmaniasis, chroman-4-one, cytotocixicity, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fchem.2020.574103/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/5e0178d1cf3243b9a6a36bf3df7a7774

المؤلفون: Samya S. Alenezi, Naif D. Alenezi, Godwin U. Ebiloma, Manal J. Natto, Marzuq A. Ungogo, John O. Igoli, Valerie A. Ferro, Alexander I. Gray, James Fearnley, Harry P. de Koning, David G. Watson

المصدر: Molecules, Vol 27, Iss 5, p 1622 (2022)

مصطلحات موضوعية: triterpenes, T. brucei, T. congolense, Papua New Guinea, propolis, U947 cells, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/5/1622; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/975c2535760043c686171cdcfa35f366

المؤلفون: Adullah Alotaibi, Godwin U. Ebiloma, Roderick Williams, Ibrahim A. Alfayez, Manal J. Natto, Sameah Alenezi, Weam Siheri, Malik AlQarni, John O. Igoli, James Fearnley, Harry P. De Koning, David G. Watson

المصدر: Molecules, Vol 26, Iss 13, p 3912 (2021)

مصطلحات موضوعية: temperate propolis, flavonoids, isolated compounds, Trypanosoma brucei, Leishmania mexicana, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/13/3912; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/aa43d65e6146473c98f129abb5126b9a

المؤلفون: Anastasia L. Khandazhinskaya, Elena S. Matyugina, Pavel N. Solyev, Maggie Wilkinson, Karen W. Buckheit, Robert W. Buckheit, Larisa N. Chernousova, Tatiana G. Smirnova, Sofya N. Andreevskaya, Khalid J. Alzahrani, Manal J. Natto, Sergey N. Kochetkov, Harry P. de Koning, Katherine L. Seley-Radtke

المصدر: Molecules, Vol 24, Iss 19, p 3433 (2019)

مصطلحات موضوعية: carbocyclic, nucleosides, tuberculosis, leishmanial, antiparasitic, mycobacterial, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/19/3433; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/a637c58484344774bb35089123f966d7

المؤلفون: Marzuq A. Ungogo, Mustafa M. Aldfer, Manal J. Natto, Hainan Zhuang, Robyn Chisholm, Katy Walsh, MarieClaire McGee, Kayhan Ilbeigi, Jamal Ibrahim Asseri, Richard J. S. Burchmore, Guy Caljon, Serge Van Calenbergh, Harry P. De Koning

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 4; Pages: 3144

مصطلحات موضوعية: Trypanosoma vivax, Trypanosoma congolense, nucleoside antimetabolite, adenosine transporter, nucleoside transporter, animal trypanosomiasis, nagana, tubercidin analog

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms24043144

الاتاحة: https://doi.org/10.3390/ijms24043144

المؤلفون: Marzuq A. Ungogo, Gustavo D. Campagnaro, Ali H. Alghamdi, Manal J. Natto, Harry P. de Koning

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2844

مصطلحات موضوعية: Trypanosoma congolense, Trypanosoma evansi, cymelarsan, pentamidine, suramin, diminazene, drug transporter, TbAT1, TbAQP2, MFST

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Microbiology; https://dx.doi.org/10.3390/ijms23052844

الاتاحة: https://doi.org/10.3390/ijms23052844

المؤلفون: Gustavo D. Campagnaro, Hamza A. A. Elati, Sofia Balaska, Maria Esther Martin Abril, Manal J. Natto, Fabian Hulpia, Kelly Lee, Lilach Sheiner, Serge Van Calenbergh, Harry P. de Koning

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 710

مصطلحات موضوعية: Toxoplasma gondii, purine transporter, Tg244440, nucleobase transporter, apicomplexan, substrate binding

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms23020710

الاتاحة: https://doi.org/10.3390/ijms23020710

المؤلفون: Mustafa M. Aldfer, Tahani A. AlSiari, Hamza A. A. Elati, Manal J. Natto, Ibrahim A. Alfayez, Gustavo D. Campagnaro, Bashiru Sani, Richard J. S. Burchmore, George Diallinas, Harry P. De Koning

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8139

مصطلحات موضوعية: equilibrative nucleoside transporter, nucleobase transport, Trypanosoma cruzi, Trichomonas vaginalis, FurD uracil transporter, Aspergillus nidulans, expression system

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms23158139

الاتاحة: https://doi.org/10.3390/ijms23158139

المؤلفون: Alexander I. Gray, Samya Alenezi, David G. Watson, Manal J. Natto, Harry P. de Koning, John O. Igoli, Hugo Fearnley, James Fearnley

المصدر: International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss, Pp 201-207 (2020)

مصطلحات موضوعية: 0301 basic medicine, Trypanosoma, 030231 tropical medicine, Trypanosoma brucei brucei, Antiprotozoal Agents, Zambia, Trypanosoma brucei, Tanzania, Article, Propolis, RS, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Trypanosomiasis, parasitic diseases, Animals, Humans, Pharmacology (medical), lcsh:RC109-216, Cytotoxicity, IC50, Pharmacology, Pinocembrin, biology, Traditional medicine, biology.organism_classification, Trypanocidal Agents, 030104 developmental biology, Infectious Diseases, chemistry, Phytochemical, Toxicity, Flavanones, Parasitology, Flavanone

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd4a2e73dba64defcf7e72609f03170
http://europepmc.org/articles/PMC7649109

المؤلفون: Gustavo D, Campagnaro, Hamza A A, Elati, Sofia, Balaska, Maria Esther, Martin Abril, Manal J, Natto, Fabian, Hulpia, Kelly, Lee, Lilach, Sheiner, Serge, Van Calenbergh, Harry P, de Koning

المصدر: International Journal of Molecular Sciences

مصطلحات موضوعية: Purinones, Tg244440, Toxoplasma gondii, Nucleosides, Nucleoside Transport Proteins, purine transporter, Fibroblasts, Article, nucleobase transporter, Gene Knockdown Techniques, Humans, substrate binding, apicomplexan, Toxoplasma, Phylogeny, Toxoplasmosis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b17f9ed0c9013c4ead1a704560476d27
https://pubmed.ncbi.nlm.nih.gov/35054895

المؤلفون: Ibrahim A. Alfayez, James Fearnley, Abdullah Alotaibi, Malik AlQarni, Godwin U. Ebiloma, David G. Watson, Sameah Alenezi, Harry P. de Koning, Roderick A.M. Williams, Manal J. Natto, Weam Siheri, John O. Igoli

المصدر: Molecules
Volume 26
Issue 13
Molecules, Vol 26, Iss 3912, p 3912 (2021)

مصطلحات موضوعية: Naringenin, Leishmania mexicana, Trypanosoma brucei, Pharmaceutical Science, Coumaric acid, 01 natural sciences, Analytical Chemistry, RS, 03 medical and health sciences, chemistry.chemical_compound, QD241-441, temperate propolis, Drug Discovery, parasitic diseases, Physical and Theoretical Chemistry, 030304 developmental biology, 0303 health sciences, Chromatography, Pinocembrin, biology, 010405 organic chemistry, Organic Chemistry, Propolis, biology.organism_classification, humanities, isolated compounds, 0104 chemical sciences, Galangin, chemistry, Chemistry (miscellaneous), flavonoids, Molecular Medicine, Kaempferol

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c03a12aae2f087da663292fe357f4a
https://eprints.gla.ac.uk/245270/1/245270.pdf

المؤلفون: Amani Alhejeli, Harry P. de Koning, Serge Van Calenbergh, Fabian Hulpia, Manal J. Natto, Susan Baillie, Eric R. Kalkman, Lars Eckmann, Yukiko Miyamoto

المصدر: ACS infectious diseases, vol 7, iss 6
ACS Infect Dis
ACS INFECTIOUS DISEASES

مصطلحات موضوعية: 0301 basic medicine, Sexually transmitted disease, tubercidin, mouse model, 030106 microbiology, Trichomonas, Sexually Transmitted Diseases, Drug Resistance, medicine.disease_cause, high-throughput screening, VALIDATION, Tubercidin, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, PURINE, INFECTION, Medicine and Health Sciences, MANAGEMENT, medicine, Trichomonas vaginalis, Animals, Humans, ASSAY, Trichomoniasis, biology, DERIVATIVES, nucleoside analog, Nucleosides, biology.organism_classification, medicine.disease, High-Throughput Screening Assays, Antitrichomonal agent, Chemistry, 030104 developmental biology, Infectious Diseases, Good Health and Well Being, chemistry, Biochemistry, METRONIDAZOLE, 5.1 Pharmaceuticals, Medical Microbiology, Sexually Transmitted Infections, Tritrichomonas foetus, Development of treatments and therapeutic interventions, Nucleoside, Biotechnology

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407a9be3496ce5a79ac0922f8c9da452
https://escholarship.org/uc/item/1tk07938

المؤلفون: John B. Nvau, Samya Alenezi, Marzuq A. Ungogo, Ibrahim A. M. Alfayez, Manal J. Natto, Alexander I. Gray, Valerie A. Ferro, Dave G. Watson, Harry P. de Koning, John O. Igoli

مصطلحات موضوعية: Biochemistry, Environmental Chemistry, Geochemistry, Organic Chemistry, Inorganic Chemistry, Nuclear Chemistry, Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics), Medical Biochemistry and Metabolomics not elsewhere classified, Food Chemistry and Molecular Gastronomy (excl. Wine), Analytical Biochemistry, Cell Neurochemistry, Enzymes, Electroanalytical Chemistry, Analytical Chemistry not elsewhere classified, Organic Green Chemistry, Physical Organic Chemistry, Catalysis and Mechanisms of Reactions, Environmental Chemistry (incl. Atmospheric Chemistry), diterpene, trypanosomiasis, leishmaniasis, chroman-4-one, cytotocixicity

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Antiparasitic_and_Cytotoxic_Activity_of_Bokkosin_A_Novel_Diterpene-Substituted_Chromanyl_Benzoquinone_From_Calliandra_portoricensis_docx/13245314

الاتاحة: https://doi.org/10.3389/fchem.2020.574103.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Antiparasitic_and_Cytotoxic_Activity_of_Bokkosin_A_Novel_Diterpene-Substituted_Chromanyl_Benzoquinone_From_Calliandra_portoricensis_docx/13245314

المؤلفون: Francesca Savioli, Neils B. Quashie, Christophe Dardonville, Boris Rodenko, Harry P. de Koning, Manal J. Natto

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Male, Microbiology (medical), Metabolite, Trichomonas, Antiprotozoal Agents, medicine.disease_cause, Fluorescence, Microbiology, chemistry.chemical_compound, Parasitic Sensitivity Tests, Oxazines, Trichomonas vaginalis, medicine, Humans, Pharmacology (medical), Propidium iodide, Pharmacology, Staining and Labeling, biology, Resazurin, Ascorbic acid, biology.organism_classification, Molecular biology, High-Throughput Screening Assays, Staining, Metronidazole, Infectious Diseases, Xanthenes, chemistry, Female, Propidium, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b205196931065734ddae077338253d5b
https://doi.org/10.1093/jac/dkr572

المؤلفون: Manal J, Natto, Anthonius A, Eze, Harry P, de Koning

المصدر: Methods in molecular biology (Clifton, N.J.). 1263

مصطلحات موضوعية: Parasitic Sensitivity Tests, Drug Evaluation, Preclinical, Trichomonas vaginalis, Humans, Antitrichomonal Agents, High-Throughput Screening Assays

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::45301bb6c69f57f777d9a9149828e927
https://pubmed.ncbi.nlm.nih.gov/25618339

المؤلفون: Manal J. Natto, Anthonius A. Eze, Harry P. de Koning

المصدر: Methods in Molecular Biology ISBN: 9781493922680

مصطلحات موضوعية: Drug, Trichomoniasis, media_common.quotation_subject, Drug resistance, Biology, medicine.disease_cause, medicine.disease, Metronidazole, Drug development, Immunology, High-Throughput Screening Assays, Human parasite, medicine, Trichomonas vaginalis, medicine.drug, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ff4fe7f26f5fb739a0128696255c220e
https://doi.org/10.1007/978-1-4939-2269-7_8

المؤلفون: Manal J. Natto, Juan A. Subirana, Harry P. de Koning, Christophe Dardonville, J. Lourdes Campos, F.J. Acosta-Reyes

المساهمون: Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. MACROM - Cristal·lografia, Estructura i Funció de Macromolècules Biològiques

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
Universitat Jaume I
Acta Crystallographica Section D: Biological Crystallography

مصطلحات موضوعية: Drug, Base pair, media_common.quotation_subject, Sequence (biology), Biology, DNA--Structure, Crystallography, X-Ray, medicine.disease_cause, d(AAAATTTT)2, DNA sequencing, chemistry.chemical_compound, Enginyeria química [Àrees temàtiques de la UPC], Structural Biology, Trichomonas vaginalis, medicine, minor-groove binding drug, Imidazolines, CD27, media_common, Trichomoniasis, Diphenylamine, ADN -- Estructura, Plasmodium falciparum, d(AAAATTTT, DNA, General Medicine, biology.organism_classification, medicine.disease, Research Papers, Medicaments -- Interacció, AT-rich DNA, chemistry, Biochemistry, Nucleic Acid Conformation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2690c7cf2ddd36847e6f3039c4968995
https://hdl.handle.net/2117/23505

المؤلفون: Mohammed I. Al-Salabi, Harry P. de Koning, Denise Candlish, Manal J. Natto, Shona E. Coutts, Lynsey J. M. Wallace

المصدر: Experimental parasitology. 109(2)

مصطلحات موضوعية: Purine, Allopurinol, Immunology, Trypanosoma brucei brucei, Drug Resistance, Protozoan Proteins, Drug resistance, Trypanosoma brucei, chemistry.chemical_compound, parasitic diseases, medicine, Nucleobase Transport Proteins, Animals, Hypoxanthine, biology, Dose-Response Relationship, Drug, Kinetoplastida, Transporter, General Medicine, biology.organism_classification, Trypanocidal Agents, Infectious Diseases, chemistry, Biochemistry, Gene Expression Regulation, Trypanosoma, Parasitology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b3e2a2cc9e805f4fc24db54f0da24c
https://pubmed.ncbi.nlm.nih.gov/15687014