المؤلفون: Malcolm Rowland

المصدر: Drug Metabolism and Pharmacokinetics. 1992, 7(supplement):585

المؤلفون: Malcolm Rowland, K. Sandy Pang

المصدر: Clinical Pharmacology & Therapeutics. 111:1205-1207

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f379dde937d9b9aac433f39f234fbb0e
https://doi.org/10.1002/cpt.2525

المؤلفون: Hiroyuki Kusuhara, Tal Burt, Oliver Langer, Graeme Young, Malcolm Rowland, Wooin Lee, Yuichi Sugiyama

المصدر: Nature Reviews Drug Discovery. 19:801-818

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Clinical pharmacology, Microdosing, Computer science, Translational research, General Medicine, Phase (combat), law.invention, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug development, Risk analysis (engineering), law, 030220 oncology & carcinogenesis, SAFER, Drug Discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bc66b724f327cc9bebc7bc0b608ed331
https://doi.org/10.1038/s41573-020-0080-x

المؤلفون: Darrell R. Abernethy, Balaji Agoram, John M. Allen, Mark E. Arnold, Arthur J. Atkinson, Thomas J. Bateman, Kimberly Bergman, Brian Booth, David W. Boulton, Robert A. Branch, Gilbert J. Burckart, Mary Buschmann, Owen Carmichael, Christine Chamberlain, Ligong Chen, Charles E. Daniels, Promi Das, Jana G. Delfino, John N. Van Den Anker, Albert W. Dreisbach, Michael Dyszel, Justin C. Earp, M. Khair ElZarrad, Osatohanmwen J. Enogieru, Elimika Pfuma Fletcher, David M. Foster, Marilynn C. Frederiksen, Aleksandra Galetin, Pamela D. Garzone, Kathleen M. Giacomini, Megan A. Gibbs, Jack A Gilbert, Danijela Gnjidic, Charles T. Gombar, Denis M. Grant, Charles Grudzinskas, Bengt Hamren, Nicholas H.G. Holford, Shiew-Mei Huang, Renee Iacona, Nina Isoherranen, Denise Jin, Bridgette L. Jones, Gregory L. Kearns, Cindy Kortepeter, Elizabeth Kunkoski, S.W. Johnny Lau, Christopher Leptak, Juan J.L. Lertora, Lawrence J. Lesko, Jiang Liu, Qi Liu, Rajanikanth Madabushi, Raymond Miller, Diane R. Mould, Monica Muñoz, Thomas D. Nolin, Robert Joseph Noveck, R. Scott Obach, Michael Pacanowski, Mary F. Paine, Carl C. Peck, Anuradha Ramamoorthy, A. David Rodrigues, Malcolm Rowland, Chandrahas G. Sahajwalla, Martina Dagmar Sahre, Robert N. Schuck, Khushboo Sharma, Tristan Sissung, Catherine S. Stika, Chris H. Takimoto, Helen Tomkinson, Jack Uetrecht, Paolo Vicini, Karen D. Vo, John A. Wagner, Yaning Wang, Yow-Ming C. Wang, Peter G. Wells, Michael J. Wick, Sook Wah Yee, Ophelia Yin, Nathalie K. Zgheib, Lei Zhang, Hao Zhu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::848d2065918d75dffbea67f6015e7476
https://doi.org/10.1016/b978-0-12-819869-8.09990-0

المؤلفون: Malcolm Rowland

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::afa400b6dba68358296dc13519343c98
https://doi.org/10.1016/b978-0-12-819869-8.00007-0

المؤلفون: Malcolm Rowland, Dennis Allen Smith

المصدر: Drug Metabolism and Disposition. 47:665-672

مصطلحات موضوعية: Drug, media_common.quotation_subject, Pharmaceutical Science, Communicable Diseases, 030226 pharmacology & pharmacy, Permeability, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Extracellular, Animals, Humans, Distribution (pharmacology), Compartment (pharmacokinetics), media_common, Pharmacology, Chemistry, Biological Transport, Small molecule, Unbound drug, 030220 oncology & carcinogenesis, Inactivation, Metabolic, Biophysics, Steady state (chemistry), Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c68e78588b225552632e59bcc4ed30b
https://doi.org/10.1124/dmd.118.085951

المؤلفون: Malcolm Rowland, K. Sandy Pang, Michael S. Roberts

المساهمون: Rowland, Malcolm, Roberts, Michael S, Pang, K Sandy

المصدر: The AAPS Journal

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Physiologically based pharmacokinetic modelling, business.industry, Drug elimination, Metabolic Clearance Rate, Pharmaceutical Science, Hepatic clearance, clearance, well-stirred model, drug development, elimination rate, Models, Biological, Kinetics, Drug development, Drug Development, Liver, Current practice, Commentary, Medicine, business, Intensive care medicine, chemical reaction engineering models

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc246f77224f4aafe1d2ba8322889903
https://pubmed.ncbi.nlm.nih.gov/33973074

المؤلفون: Tal, Burt, Graeme, Young, Wooin, Lee, Hiroyuki, Kusuhara, Oliver, Langer, Malcolm, Rowland, Yuichi, Sugiyama

المصدر: Nature reviews. Drug discovery. 19(11)

مصطلحات موضوعية: Clinical Trials as Topic, Drug Development, Animals, Humans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9bbd929516110bb8902862ab98ebae21
https://pubmed.ncbi.nlm.nih.gov/32901140

المؤلفون: Thierry Lavé, Robert A.B. van Waterschoot, Andrés Olivares-Morales, Neil Parrott, Dennis A. Smith, Malcolm Rowland

المصدر: Drug Discovery Today. 23:2023-2030

مصطلحات موضوعية: Pharmacology, Drug, Clinical Trials as Topic, Drug disposition, Drug discovery, Microdosing, Chemistry, media_common.quotation_subject, Target concentration, 030226 pharmacology & pharmacy, Small molecule, Small Molecule Libraries, 03 medical and health sciences, Drug Delivery Systems, 0302 clinical medicine, Pharmacokinetics, In vivo, 030220 oncology & carcinogenesis, Drug Discovery, Animals, Humans, Tissue Distribution, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8145ad1b58c8847d400cc5a32a77dd
https://doi.org/10.1016/j.drudis.2018.06.010

المؤلفون: Jennifer B. Dressman, Amin Rostami-Hodjegan, Rodrigo Cristofoletti, Lawrence J. Lesko, Henning Blume, Malcolm Rowland

المصدر: Journal of Pharmaceutical Sciences. 107:2519-2530

مصطلحات موضوعية: Computer science, media_common.quotation_subject, Product testing, Administration, Oral, Pharmaceutical Science, Bayes Theorem, Context (language use), Bioequivalence, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Drug Development, Pharmaceutical Preparations, Therapeutic Equivalency, Risk analysis (engineering), 030220 oncology & carcinogenesis, Paradigm shift, Animals, Humans, Quality (business), Regulatory science, Systems thinking, Product (category theory), media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c105d98a6da751ad4e99cff3387f3e89
https://doi.org/10.1016/j.xphs.2018.06.013

المؤلفون: Berend Oosterhuis, Brian Houston, Charlotte Gesson, Colin Garner, Malcolm Rowland, Ole J. Bjerrum, Richard John Weaver, Roeline Jochemsen, Yoko Shishikura, Graham Lappin

مصطلحات موضوعية: B230 - Pharmacy, Absolute oral bioavailability, Accelerator mass spectrometry, AMS fexofenadine, Microdosing

Relation: 10779/lincoln.24404473.v1; https://figshare.com/articles/journal_contribution/Pharmacokinetics_of_fexofenadine_evaluation_of_a_microdose_and_assessment_of_absolute_oral_bioavailability/24404473

الاتاحة: https://figshare.com/articles/journal_contribution/Pharmacokinetics_of_fexofenadine_evaluation_of_a_microdose_and_assessment_of_absolute_oral_bioavailability/24404473

المؤلفون: S Y A Cheung, Malcolm Rowland, C Brown, B Collins, S Murby, Ivelina Gueorguieva, Gemma L. Dickinson, Leon Aarons, T Rodgers

المصدر: British Journal of Pharmacology. 175:67-83

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Physiologically based pharmacokinetic modelling, Chemistry, 030226 pharmacology & pharmacy, Acebutolol, Betaxolol, NONMEM, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Pharmacokinetics, Bisoprolol, Oxprenolol, medicine, Distribution (pharmacology), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::613d570de32c60362ae0061ae07a2453
https://doi.org/10.1111/bph.14071

المؤلفون: Tal Burt, D. K. Demasi, Malcolm Rowland, D. C. MacLeod, Mark N. Feinglos, K. Lee, Thomas C. Hawk, Antoinette Santoro, Robert J. Noveck

المصدر: Clinical and Translational Science. 10:351-359

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Microdosing, medicine.medical_treatment, 030204 cardiovascular system & hematology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Therapeutic index, MicroDose, Internal medicine, medicine, General Pharmacology, Toxicology and Pharmaceutics, medicine.diagnostic_test, business.industry, General Neuroscience, Insulin, General Medicine, 3. Good health, 030104 developmental biology, Drug development, Positron emission tomography, Drug delivery, Systemic administration, business, Nuclear medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1341a679b096c8b952e50d938749331b
https://doi.org/10.1111/cts.12477

المؤلفون: Graham Lappin, Anita T. Layton, Robert J. Noveck, Malcolm Rowland, David B. MacLeod, Tal Burt

المصدر: Clinical and Translational Science. 10:337-350

مصطلحات موضوعية: Drug, medicine.medical_specialty, Extramural, Microdosing, business.industry, General Neuroscience, media_common.quotation_subject, MEDLINE, Translation (biology), General Medicine, Pharmacology, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Drug development, SAFER, medicine, Medical physics, General Pharmacology, Toxicology and Pharmaceutics, business, 030217 neurology & neurosurgery, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f72bdc6112cbd016151ba6447946edfd
https://doi.org/10.1111/cts.12464

المؤلفون: Malcolm Rowland, Ping I. Lee, Yi Rang Han, K. Sandy Pang, Keumhan Noh

المصدر: Biochemical pharmacology. 169

مصطلحات موضوعية: 0301 basic medicine, Metabolizing enzymes, Metabolic Clearance Rate, Hepatic clearance, Transit time, Biochemistry, Models, Biological, 03 medical and health sciences, Biliary excretion, 0302 clinical medicine, Animals, Humans, Tissue Distribution, Specific model, Pharmacology, Chemistry, Substrate concentration, Rats, Hepatobiliary Elimination, 030104 developmental biology, Liver, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Hepatocytes, Hepatic Elimination, Biological system, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15c2a18908d10dd2efedf02b558761d
https://pubmed.ncbi.nlm.nih.gov/31398312

المؤلفون: Ivan Nestorov, Ivelina Gueorguieva, Hannah M. Jones, Brian Houston, Malcolm Rowland

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dmd.aspetjournals.org/cgi/reprint/30/3/276.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.132.8177; http://dmd.aspetjournals.org/cgi/reprint/30/3/276.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.132.8177
http://dmd.aspetjournals.org/cgi/reprint/30/3/276.pdf

المؤلفون: Fernandez-Alvarez, J.M. (José María), Buckley, E. (Eileen), Shearan, P. (Paula), Smyth, M.R. (Malcolm Rowland)

مصطلحات موضوعية: Avidin, Streptavidin, Immunoglobulins, Alanine transaminase, Creatinine kinase, Adsorptive voltammetry

وصف الملف: application/pdf

Relation: https://hdl.handle.net/10171/58913

الاتاحة: https://hdl.handle.net/10171/58913

المؤلفون: Yuichi Sugiyama, Malcolm Rowland, Christy S. John, Kenta Yoshida, SN de Wildt, Graham Lappin, L Vuong, Tal Burt

المصدر: Clinical and Translational Science. 9:74-88

مصطلحات موضوعية: Flexibility (engineering), Drug, Drug discovery, Microdosing, business.industry, General Neuroscience, media_common.quotation_subject, Phases of clinical research, General Medicine, Pharmacology, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Pre-clinical development, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Drug development, Risk analysis (engineering), 030220 oncology & carcinogenesis, Medicine, General Pharmacology, Toxicology and Pharmaceutics, business, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::73926ac6916a6f37f4919b3cda74a562
https://doi.org/10.1111/cts.12390

المؤلفون: K. Sandy Pang, Malcolm Rowland

المصدر: Clinical Pharmacology & Therapeutics. 103:386-388

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Clinical pharmacology, business.industry, Hepatic clearance, 030226 pharmacology & pharmacy, law.invention, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Drug development, law, 030220 oncology & carcinogenesis, medicine, Pharmacology (medical), Intensive care medicine, business, Clearance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::03ee3759f5c9be58e0907ed959eab5fa
https://doi.org/10.1002/cpt.921

المؤلفون: Malcolm Rowland, Manoranjenni Chetty, Masoud Jamei, Katherine L. Gill, Helen Musther, Amin Rostami-Hodjegan

المصدر: The AAPS Journal

مصطلحات موضوعية: physiological model, Physiologically based pharmacokinetic modelling, business.industry, Cmax, Pharmaceutical Science, Sampling (statistics), Pharmacology, Models, Biological, Peripheral, Pharmaceutical Preparations, Pharmacokinetics, intravenous, Plasma concentration, PBPK modelling, Animals, Humans, Medicine, Administration, Intravenous, Blood supply, business, Compartment (pharmacokinetics), Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a554942e98940db3e02ae5d2f2b87eef
https://doi.org/10.1208/s12248-015-9796-7