المؤلفون: Norikazu Ohtake, Tomoharu Iino, Yasuhiro Sasaki, Hideka Hosaka, Akio Ohno, Morihiro Mitsuya, Hiroko Maruki, Kaori Sasaki, Makoto Bamba, Masato Chiba, Kenji Kamata, Yasufumi Nagata, Jun-ichi Eiki, Riki Yoshimoto, Teruyuki Nishimura, Mayumi Futamura, Sumika Ohyama

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5531-5538

مصطلحات موضوعية: Blood Glucose, Chemistry, Stereochemistry, Activator (genetics), Glucokinase, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Rats, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Aqueous solubility, Quinazolines, Glucokinase activator, Quinazoline, Animals, Hypoglycemic Agents, Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a3e10f301b93c8f676112dfbb184e7
https://doi.org/10.1016/j.bmcl.2009.08.064

المؤلفون: Yasufumi Nagata, Mayumi Futamura, Tomoharu Iino, Jun-ichi Eiki, Hitomi Watanabe, Sumika Ohyama, Hideka Hosaka, Makoto Bamba, Morihiro Mitsuya, Teruyuki Nishimura, Kenji Kamata, Daisuke Tsukahara, Kaori Sasaki

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:1357-1360

مصطلحات موضوعية: Male, Clinical Biochemistry, Allosteric regulation, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Allosteric Regulation, In vivo, Glucokinase, Drug Discovery, Glucokinase activator, Animals, Transferase, Structure–activity relationship, Rats, Wistar, Benzamide, Molecular Biology, Binding Sites, Organic Chemistry, Rats, Enzyme Activation, chemistry, Benzamides, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4615ec64103f3fa03ebf9d3d812e2e
https://doi.org/10.1016/j.bmcl.2009.01.053

المؤلفون: Mari Yonemoto, Hitomi Watanabe, Yoshiyuki Sato, Makoto Bamba, Satoru Ito, Toshio Nagase, Jun-ichi Eiki, Kaori Saeki, Sumika Ohyama, Toshihiko Yada, Akio Kanatani, Norihiro Nagano, Teruyuki Nishimura, Yoko Takayenoki-Iino, Tomoharu Iino, Kaori Sasaki

المصدر: The Journal of endocrinology. 201(3)

مصطلحات موضوعية: Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Enteroendocrine Cells, Drug Evaluation, Preclinical, Enteroendocrine cell, Biology, Isoindoles, PC12 Cells, Membrane Potentials, Substrate Specificity, Mice, Endocrinology, Glucagon-Like Peptide 1, Pregnancy, Internal medicine, medicine, Extracellular, Animals, Secretion, Rats, Wistar, Oxazoles, Cells, Cultured, Secretory Pathway, Depolarization, Calcium Channel Blockers, Rats, Calcium Channel Agonists, Mechanism of action, Verapamil, Secretagogue, Calcium, Female, medicine.symptom, Signal transduction, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cad09d2e9395e586a0f8ce292945c27
https://pubmed.ncbi.nlm.nih.gov/19332449

المؤلفون: Yasuhiro Sasaki, Kenji Kamata, Yasufumi Nagata, Kaori Sasaki, Morihiro Mitsuya, Hitomi Watanabe, Hideka Hosaka, Jun-ichi Eiki, Makoto Bamba, Sumika Ohyama, Teruyuki Nishimura

المصدر: Bioorganicmedicinal chemistry letters. 19(10)

مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Drug Discovery, Glucokinase, medicine, Transferase, Structure–activity relationship, Animals, Hypoglycemic Agents, Molecular Biology, chemistry.chemical_classification, Chemistry, Drug discovery, Organic Chemistry, Chemical modification, Biological activity, Amides, Rats, Disease Models, Animal, Enzyme, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e133990e9137dc1d7847646326c83526
https://pubmed.ncbi.nlm.nih.gov/19362831