المؤلفون: Yang, Ying, Paivinen, Pekka, Xie, Chang, Krup, Alexis Leigh, Makela, Tomi P, Mostov, Keith E, Reiter, Jeremy F

المصدر: Nature Communications. 12(1)

مصطلحات موضوعية: Biological Sciences, Medical Physiology, Biomedical and Clinical Sciences, Digestive Diseases, Animals, Cell Proliferation, Cilia, Gastrointestinal Tract, Hedgehog Proteins, Mesoderm, Mice, Muscle, Smooth, Myocytes, Smooth Muscle, Protein Serine-Threonine Kinases, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7v0417p7
https://escholarship.org/content/qt7v0417p7/qt7v0417p7.pdf

المؤلفون: Kuuluvainen, Emilia, Domenech-Moreno, Eva, Niemela, Elina H., Makela, Tomi P.

المساهمون: Centre of Excellence in Stem Cell Metabolism, Helsinki Institute of Life Science HiLIFE, Joint Activities, Research Programs Unit, Helsinki Institute of Life Science HiLIFE, Medicum, Mäkelä Lab

مصطلحات موضوعية: BRD4, CDK19, CDK8, cancer, MED12, MED13, MED13L, Mediator, superenhancer, transcription, SUPER-ENHANCERS, TRANSCRIPTION FACTORS, SELECTIVE-INHIBITION, COLORECTAL-CANCER, EXPRESSION, RNA, MICE, ELONGATION, LEUKEMIA, Biochemistry, cell and molecular biology

وصف الملف: application/pdf

Relation: This work was supported by grants from the Academy of Finland (projects 1259278 and 12718454), Biocentrum Helsinki, Finnish cancer organizations, and the Sigrid Juselius Foundation to T.P.M. and by grants from Svenska Kulturfonden, the K. Albin Johansson Foundation, the Oskar Oflund Foundation, the Biomedicum Helsinki Foundation, the Ida Montin Foundation, and the Paulo Foundation to E.K.; Kuuluvainen , E , Domenech-Moreno , E , Niemela , E H & Makela , T P 2018 , ' Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells ' , Molecular and Cellular Biology , vol. 38 , no. 12 , UNSP e00573-17 . https://doi.org/10.1128/MCB.00573-17; ORCID: /0000-0002-2562-1060/work/45439411; ORCID: /0000-0002-4869-8044/work/45438977; http://hdl.handle.net/10138/298268; 6f4529f4-ab6e-4b0f-aa34-1aa355504f67; 85046945273; 000432179500006

الاتاحة: http://hdl.handle.net/10138/298268

المؤلفون: Kovac, Bianca, Makela, Tomi P., Vallenius, Tea

المساهمون: Research Programs Unit, Helsinki Institute of Life Science HiLIFE, Joint Activities, Doctoral Programme in Integrative Life Science, Medicum, Mäkelä Lab, Helsinki Institute of Life Science HiLIFE

مصطلحات موضوعية: GROWTH-FACTOR-BETA, EPITHELIAL-MESENCHYMAL TRANSITION, CELL-CELL JUNCTIONS, ALPHA-ACTININ, GENE-EXPRESSION, INDEPENDENT MANNER, ADHERENS JUNCTIONS, OVARIAN-CANCER, TGF-BETA, INVASION, Biomedicine, Cancers

وصف الملف: application/pdf

Relation: The authors acknowledge salary funding from the Academy of Finland (TM. and B.K., grant numbers 258837 and 265170); Integrative Life Science Graduate School, University of Helsinki (B.K.), Instrumentarium Science Foundation and The Maud Kuistila Memorial Foundation (B.K.). In addition, Finnish Medical Foundation and Biocentrum Helsinki supported this work. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; Kovac , B , Makela , T P & Vallenius , T 2018 , ' Increased alpha-actinin-1 destabilizes E-cadherin-based adhesions and associates with poor prognosis in basal-like breast cancer ' , PLoS One , vol. 13 , no. 5 , 0196986 . https://doi.org/10.1371/journal.pone.0196986; ORCID: /0000-0002-4869-8044/work/46650109; http://hdl.handle.net/10138/237101; 9b2e36f7-7483-49dd-ab6d-4291e62a867d; 85046832281; 000431757400053

الاتاحة: http://hdl.handle.net/10138/237101

المؤلفون: Georgiadou, Maria, Lilja, Johanna, Jacquemet, Guillaume, Guzman, Camilo, Rafaeva, Maria, Alibert, Charlotte, Yan, Yan, Sahgal, Pranshu, Lerche, Martina, Manneville, Jean-Baptiste, Makela, Tomi P., Ivaska, Johanna

المساهمون: University of Helsinki, Research Programs Unit, Mäkelä Lab

مصطلحات موضوعية: ACTIVATED PROTEIN-KINASE, CELL-MATRIX ADHESIONS, FIBRONECTIN FIBRILLOGENESIS, TRACTION FORCES, GENETIC SCREEN, LIVING CELLS, MYOSIN-II, IN-VIVO, DYNAMICS, GROWTH, Biomedicine, Biochemistry, cell and molecular biology

وصف الملف: application/pdf

Relation: This study has been supported by the Academy of Finland, the Sigrid Juselius Foundation, and the Cancer Society of Finland (to J. Ivaska and T.P. Makela) and by a European Research Council Consolidator (grant 615258 to J. Ivaska). M. Georgiadou and G. Jacquemet are supported by a European Molecular Biology Organization Long-Term Fellowship. J. Lilja and P. Sahgal are supported by the University of Turku Doctoral Program of Molecular Medicine. Y. Yan is supported by the Doctoral Program in Biomedicine and the Finnish Cultural Foundation. C. Alibert and J.-B. Manneville were supported by grants from Universite Pierre et Marie Curie University Paris 6 (Program Doctoral Interfaces Pour le Vivant) and from the Plan Cancer 2012 Institut National de la Sante et de la Recherche Medicale-Tecsan grant PC201125.; Georgiadou , M , Lilja , J , Jacquemet , G , Guzman , C , Rafaeva , M , Alibert , C , Yan , Y , Sahgal , P , Lerche , M , Manneville , J-B , Makela , T P & Ivaska , J 2017 , ' AMPK negatively regulates tensin-dependent integrin activity ' , Journal of Cell Biology , vol. 216 , no. 4 , pp. 1107-1121 . https://doi.org/10.1083/jcb.201609066; ORCID: /0000-0002-4869-8044/work/33531842; http://hdl.handle.net/10138/187584; e009cc2d-8836-4e65-87a5-622398f2b777; 85020268113; 000398052700022

الاتاحة: http://hdl.handle.net/10138/187584

المؤلفون: Makela, Tomi P., Parvin, Jeffrey D., Kim, Jaesang, Huber, L. Julie, Sharp, Phillip A., Weinberg, Robert A.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1995 May . 92(11), 5174-5178.

URL الوصول: https://www.jstor.org/stable/2367694

المؤلفون: Partanen, Juha, Makela, Tomi P., Alitalo, Riitta, Lehvaslaiho, Heikki, Alitalo, Kari

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1990 Nov 01. 87(22), 8913-8917.

URL الوصول: https://www.jstor.org/stable/2355657

المؤلفون: Kurki, Mitja, I, Karjalainen, Juha, Palta, Priit, Sipila, Timo P., Kristiansson, Kati, Donner, Kati M., Reeve, Mary P., Laivuori, Hannele, Aavikko, Mervi, Kaunisto, Mari A., Loukola, Anu, Lahtela, Elisa, Mattsson, Hannele, Laiho, Päivi, Parolo, Pietro Della Briotta, Lehisto, Arto A., Kanai, Masahiro, Mars, Nina, Ramo, Joel, Kiiskinen, Tuomo, Heyne, Henrike O., Veerapen, Kumar, Rueger, Sina, Lemmelä, Susanna, Zhou, Wei, Ruotsalainen, Sanni, Parn, Kalle, Hiekkalinna, Tero, Koskelainen, Sami, Paajanen, Teemu, Llorens, Vincent, Gracia-Tabuenca, Javier, Siirtola, Harri, Reis, Kadri, Elnahas, Abdelrahman G., Sun, Benjamin, Foley, Christopher N., Aalto-Setala, Katriina, Alasoo, Kaur, Arvas, Mikko, Auro, Kirsi, Biswas, Shameek, Bizaki-Vallaskangas, Argyro, Carpen, Olli, Chen, Chia-Yen, Dada, Oluwaseun A., Ding, Zhihao, Ehm, Margaret G., Eklund, Kari, Farkkila, Martti, Finucane, Hilary, Ganna, Andrea, Ghazal, Awaisa, Graham, Robert R., Green, Eric M., Hakanen, Antti, Hautalahti, Marco, Hedman, Asa K., Hiltunen, Mikko, Hinttala, Reetta, Hovatta, Iiris, Hu, Xinli, Huertas-Vazquez, Adriana, Huilaja, Laura, Hunkapiller, Julie, Jacob, Howard, Jensen, Jan-Nygaard, Joensuu, Heikki, John, Sally, Julkunen, Valtteri, Jung, Marc, Junttila, Juhani, Kaarniranta, Kai, Kahonen, Mika, Kajanne, Risto, Kallio, Lila, Kalviainen, Reetta, Kaprio, Jaakko, FinnGen, Kerimov, Nurlan, Kettunen, Johannes, Kilpelainen, Elina, Kilpi, Terhi, Klinger, Katherine, Kosma, Veli-Matti, Kuopio, Teijo, Kurra, Venla, Laisk, Triin, Laukkanen, Jari, Lawless, Nathan, Liu, Aoxing, Longerich, Simonne, Magi, Reedik, Makela, Johanna, Makitie, Antti, Malarstig, Anders, Mannermaa, Arto, Maranville, Joseph, Matakidou, Athena, Meretoja, Tuomo, Mozaffari, Sahar, V, Niemi, Mari E. K., Niemi, Marianna, Niiranen, Teemu, Okafo, George, Ollila, Hanna M., Palomaki, Antti, Palotie, Tuula, Partanen, Jukka, Paul, Dirk S., Pelkonen, Margit, Pendergrass, Rion K., Petrovski, Slave, Pitkaranta, Anne, Platt, Adam, Pulford, David, Punkka, Eero, Pussinen, Pirkko, Raghavan, Neha, Rahimov, Fedik, Rajpal, Deepak, Renaud, Nicole A., Riley-Gillis, Bridget, Rodosthenous, Rodosthenis, Saarentaus, Elmo, Salminen, Aino, Salminen, Eveliina, Salomaa, Veikko, Schleutker, Johanna, Serpi, Raisa, Shen, Huei-yi, Siegel, Richard, Silander, Kaisa, Siltanen, Sanna, Soini, Sirpa, Soininen, Hilkka, Sul, Jae Hoon, Tachmazidou, Ioanna, Tasanen, Kaisa, Tienari, Pentti, Toppila-Salmi, Sanna, Tukiainen, Taru, Tuomi, Tiinamaija, Turunen, Joni A., Ulirsch, Jacob C., Vaura, Felix, Virolainen, Petri, Waring, Jeffrey, Waterworth, Dawn, Yang, Robert, Nelis, Mari, Reigo, Anu, Metspalu, Andres, Milani, Lili, Esko, Tonu, Fox, Caroline, Havulinna, Aki S., Perola, Markus, Ripatti, Samuli, Jalanko, Anu, Laitinen, Tarja, Makela, Tomi P., Plenge, Robert, McCarthy, Mark, Runz, Heiko, Daly, Mark J., Palotie, Aarno

المصدر: WOS ; WOS:000928299100001

وصف الملف: 508-518

Relation: NATURE; 7944; 613; https://www.julkari.fi/handle/10024/146260

الاتاحة: https://www.julkari.fi/handle/10024/146260

المؤلفون: Lizcano, Jose M, Göransson, Olga, Toth, Rachel, Deak, Maria, Morrice, Nick A, Boudeau, Jerome, Hawley, Simon A, Udd, Lina, Makela, Tomi P, Hardie, D Grahame, Alessi, Dario R

المصدر: EMBO Journal. 23(4):833-843

مصطلحات موضوعية: diabetes, PAR1/MARK kinase, cancer, cell polarity, TOF–TOF mass spectrometry, Peutz–Jeghers syndrome, Naturvetenskap, Biologi, Biokemi och molekylärbiologi, Natural Sciences, Biological Sciences, Biochemistry and Molecular Biology

URL الوصول: https://lup.lub.lu.se/record/1129488
http://dx.doi.org/10.1038/sj.emboj.7600110

المؤلفون: Hawley, Simon A., Boudeau, Jerome, Reid, Jennifer L., Mustard, Kirsty J., Udd, Lina, Makela, Tomi P., Alessi, Dario R., Hardie, D. Grahame

المصدر: Hawley , S A , Boudeau , J , Reid , J L , Mustard , K J , Udd , L , Makela , T P , Alessi , D R & Hardie , D G 2003 , ' Complexes between the LKB1 tumor suppressor, STRAD α/β and MO25 α/β are upstream kinases in the AMP-activated protein kinase cascade ' , Journal of Biology , vol. 2 , no. 4 , pp. 28 . https://doi.org/10.1186/1475-4924-2-28

الاتاحة: https://discovery.dundee.ac.uk/en/publications/0b03a9f5-a535-4a70-8516-2cefcb3dd147
https://doi.org/10.1186/1475-4924-2-28

المؤلفون: Sano, Motoaki, Shirai, Manabu, Rossi, Derrick J., Makela, Tomi P., Taffet, George E., Youker, Keith A., Michael, Lloyd H., Entman, Mark L., Schwartz, Robert J., Schneider, Michael D.

المصدر: Journal of Cardiac Failure ; volume 9, issue 5, page S4 ; ISSN 1071-9164

الاتاحة: http://dx.doi.org/10.1016/s1071-9164(03)00165-9
https://api.elsevier.com/content/article/PII:S1071916403001659?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1071916403001659?httpAccept=text/plain

المؤلفون: Ylikorkala, Antti, Rossi, Derrick J., Korsisaari, Nina, Luukko, Keijo, Alitalo, Kari, Henkemeyer, Mark, Mäkelä, Tomi P.

المصدر: Science ; volume 293, issue 5533, page 1323-1326 ; ISSN 0036-8075 1095-9203

الاتاحة: http://dx.doi.org/10.1126/science.1062074
https://www.science.org/doi/pdf/10.1126/science.1062074

المؤلفون: Makela, Tomi P., Kere, Juha, Winqvist, Robert, Alitalo, Kari

المصدر: Molecular and Cellular Biology ; volume 11, issue 8, page 4015-4021 ; ISSN 1098-5549

الاتاحة: http://dx.doi.org/10.1128/mcb.11.8.4015-4021.1991
https://journals.asm.org/doi/pdf/10.1128/mcb.11.8.4015-4021.1991
https://www.tandfonline.com/doi/pdf/10.1128/mcb.11.8.4015-4021.1991

المؤلفون: Akoulitchev, Sasha, Makela, Tomi P.

المصدر: Nature. 10/12/1995, Vol. 377 Issue 6549, p557. 4p. 14 Diagrams, 4 Graphs.

مصطلحات موضوعية: *TRANSCRIPTION factors, *RNA polymerases, *BIOSYNTHESIS

المؤلفون: Makela, Tomi P., Tassan, Jean-Pierre

المصدر: Nature. 9/15/1994, Vol. 371 Issue 6494, p254. 4p. 8 Black and White Photographs, 2 Charts, 1 Graph.

مصطلحات موضوعية: *PROTEIN kinases, *CELL cycle, *EUKARYOTIC cells, *CHEMICAL inhibitors

المؤلفون: Alitalo, Riitta, Makela, Tomi P., Koskinen, Paivi, Andersson, Leif C., Alitalo, Kari

المصدر: Blood; April 1988, Vol. 71 Issue: 4 p899-906, 8p

المؤلفون: Makela, Tomi

المصدر: Contemporary Music Review; January 1998, Vol. 17 Issue: 1 p57-71, 15p

المؤلفون: Serizawa, Hiroaki, Makela, Tomi P.

المصدر: Nature. 3/16/1995, Vol. 374 Issue 6519, p280. 3p. 4 Black and White Photographs, 1 Graph.

مصطلحات موضوعية: *PEPTIDES, *CHEMICAL structure