المؤلفون: Fabian C. Herrmann, Mairin Lenz, Joachim Jose, Marcel Kaiser, Reto Brun, Thomas J. Schmidt

المصدر: Molecules, Vol 20, Iss 9, Pp 16154-16169 (2015)

مصطلحات موضوعية: Trypanosoma brucei, human African trypanosomiasis, glyceraldehyde-3-phosphate dehydrogenase inhibitor, natural product, in silico screening, in vitro antitrypanosomal activity, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/20/9/16154; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/1943361338c14258b4d205317a1b0730

المؤلفون: Mairin Lenz, R. Luise Krauth-Siegel, Thomas J. Schmidt

المصدر: Molecules, Vol 24, Iss 20, p 3737 (2019)

مصطلحات موضوعية: sesquiterpene lactone, 4,15-iso-atriplicolide ester, trypanosoma brucei, trypanosoma cruzi, trypanothione reductase, irreversible inhibitor, antitrypanosomal activity, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/20/3737; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/8ebc5e1c8a784e0fa6718cdb22f132f1

المؤلفون: Anna Galkina, Nico Krause, Mairin Lenz, Constantin G. Daniliuc, Marcel Kaiser, Thomas J. Schmidt

المصدر: Molecules, Vol 24, Iss 6, p 1068 (2019)

مصطلحات موضوعية: sesquiterpene lactone, furanoheliangolide, X-ray crystallography, antiprotozoal activity, Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, Plasmodium falciparum, cytotoxicity, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/24/6/1068; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/bfbefcf267a8495bb2c4a569fafc59d6

المؤلفون: Amke Trentmann, Debora A. Casolari, Maria V. Yusenko, Henning D. Mootz, Jan-Henrik Mikesch, Karl-Heinz Klempnauer, Mairin Lenz, Maria Francisca Arteaga, Richard J D'Andrea, Wolfgang Dörner, Stefan Klempnauer, Thomas J. Schmidt, Luca Abdel Ghani, Melanie Horn, Carsten Müller-Tidow, Thomas J. Gonda

المساهمون: Yusenko, Maria V, Trentmann, Amke, Casolari, Debora A, Abdel Ghani, Luca, Lenz, Mairin, Horn, Melanie, Dörner, Wolfgang, Klempnauer, Stefan, Mootz, Henning D, Arteaga, Maria Francisca, Mikesch, Jan Henrik, D'Andrea, Richard J, Gonda, Thomas J, Müller-Tidow, Carsten, Schmidt, Thomas J, Klempnauer, Karl Heinz

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Biology, drug target, Article, Acute myeloid leukaemia, 03 medical and health sciences, 0302 clinical medicine, acute myeloid leukemia (AML), Genetics, MYB, Progenitor cell, Molecular Biology, Transcription factor, Gene, Cell growth, CCAAT-Enhancer-Binding Protein-beta, Myeloid leukemia, Cell Differentiation, MYB activity, Haematopoiesis, Leukemia, Myeloid, Acute, 030104 developmental biology, Mechanisms of disease, 030220 oncology & carcinogenesis, Cancer research, Transcription factor MYB, Ectopic expression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99594c1cb67990ef093aab785965f213
http://europepmc.org/articles/PMC8298201

المؤلفون: Marcel Kaiser, Thomas J. Schmidt, Mairin Lenz, Fabian C. Herrmann, Reto Brun, Joachim Jose

المصدر: Molecules, Vol 20, Iss 9, Pp 16154-16169 (2015)
Molecules
Volume 20
Issue 9
Pages 16154-16169

مصطلحات موضوعية: natural product, Trypanosoma brucei, in silico screening, Databases, Pharmaceutical, In silico, human African trypanosomiasis, Trypanosoma brucei brucei, Protozoan Proteins, Pharmaceutical Science, In Vitro Techniques, Article, Analytical Chemistry, lcsh:QD241-441, lcsh:Organic chemistry, Catalytic Domain, Drug Discovery, Computer Simulation, Enzyme Inhibitors, Physical and Theoretical Chemistry, Glyceraldehyde 3-phosphate dehydrogenase, in vitro antitrypanosomal activity, chemistry.chemical_classification, Biological Products, Virtual screening, Molecular Structure, biology, Organic Chemistry, Glyceraldehyde-3-Phosphate Dehydrogenases, biology.organism_classification, Trypanocidal Agents, Enzyme assay, Molecular Docking Simulation, Enzyme, chemistry, Biochemistry, Chemistry (miscellaneous), Docking (molecular), biology.protein, Molecular Medicine, Pharmacophore, glyceraldehyde-3-phosphate dehydrogenase inhibitor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab9b7c4151f2412488036c68ba7e762
http://www.mdpi.com/1420-3049/20/9/16154

المؤلفون: Fabian C. Herrmann, Thomas J. Schmidt, Mairin Lenz

المصدر: ResearcherID

مصطلحات موضوعية: Pharmacology, biology, In silico, Organic Chemistry, Pharmaceutical Science, Trypanosoma brucei, biology.organism_classification, Molecular biology, Analytical Chemistry, Enzyme inhibition, Complementary and alternative medicine, Biochemistry, Drug Discovery, biology.protein, Molecular Medicine, Identification (biology), Glyceraldehyde 3-phosphate dehydrogenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bbbf50ac78cd102416f6ab9d698e3f
https://doi.org/10.1055/s-0034-1394556

المؤلفون: Thomas J. Schmidt, L Krauth-Siegel, Mairin Lenz

المصدر: ResearcherID

مصطلحات موضوعية: Pharmacology, Complementary and alternative medicine, Biochemistry, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Trypanothione reductase, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f1a619978cc709b694d8e607195dad
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000367558100204&KeyUID=WOS:000367558100204