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المؤلفون: Ming Tan, Klaus Brusgaard, Anne‐Marie Gerdes, Martin Jakob Larsen, Michael Bau Mortensen, Sönke Detlefsen, Ove B. Schaffalitzky de Muckadell, Maiken Thyregod Joergensen
المصدر: Web of Science
Tan, M, Brusgaard, K, Gerdes, A-M, Larsen, M J, Mortensen, M B, Detlefsen, S, de Muckadell, O B S & Joergensen, M T 2022, ' Whole genome sequencing identifies rare genetic variants in familial pancreatic cancer patients ', Annals of Human Genetics, vol. 86, no. 4, pp. 195-206 . https://doi.org/10.1111/ahg.12464مصطلحات موضوعية: Pancreatic Neoplasms, whole genome sequencing, Whole Genome Sequencing, Carcinoma, protein truncating variants, Genetics, pancreatic ductal adenocarcinoma, rare variants, Humans, Genetic Predisposition to Disease, familial pancreatic cancers, Genetics (clinical)
وصف الملف: application/pdf
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المصدر: Tan, M, Schaffalitzky, O B & Jørgensen, M T 2020, ' Gene Expression Network Analysis of Precursor Lesions in Familial Pancreatic Cancer ', Journal of Pancreatic Cancer, vol. 6, no. 1, pp. 73-84 . https://doi.org/10.1089/pancan.2020.0007
Journal of Pancreatic Cancerمصطلحات موضوعية: Pancreatic ductal adenocarcinoma, endocrine system diseases, business.industry, Pancreatic Intraepithelial Neoplasia, precursor lesions, familial pancreatic cancer, network-based analysis, digestive system diseases, Gene expression, Familial Pancreatic Cancer, gene expression, Cancer research, Medicine, Original Article, business, sporadic pancreatic cancer
وصف الملف: application/pdf
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المؤلفون: Sönke Detlefsen, Anne-Marie Gerdes, Ove B. Schaffalitzky de Muckadell, Klaus Brusgaard, Michael Bau Mortensen, Ming Tan, Maiken Thyregod Joergensen
مصطلحات موضوعية: Genetics, Whole genome sequencing, Cancer related genes, Familial Pancreatic Cancer, Biology, Germline
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المؤلفون: Klaus Brusgaard, Maiken Thyregod Joergensen, Anne-Marie Gerdes, Michael Bau Mortensen, Sönke Detlefsen, Ming Tan, Ove B. Schaffalitzky de Muckadell
المصدر: Tan, M, Brusgaard, K, Gerdes, A, Mortensen, M B, Detlefsen, S, Schaffalitzky De Muckadell, O B & Joergensen, M T 2021, ' Cohort profile and heritability assessment of familial pancreatic cancer : a nation-wide study ', Scandinavian Journal of Gastroenterology, vol. 56, no. 8, pp. 965-971 . https://doi.org/10.1080/00365521.2021.1937697
Tan, M, Brusgaard, K, Gerdes, A-M A, Mortensen, M B, Detlefsen, S, Schaffalitzky, O B & Jørgensen, M T 2021, ' Cohort profile and heritability assessment of familial pancreatic cancer: a nation-wide study ', Scandinavian Journal of Gastroenterology, vol. 56, no. 8, pp. 965-971 . https://doi.org/10.1080/00365521.2021.1937697مصطلحات موضوعية: Pancreatic ductal adenocarcinoma, endocrine system diseases, Intraclass correlation, Logistic regression, Danish, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Familial Pancreatic Cancer, Medicine, Humans, Mass Screening, Genetic Predisposition to Disease, business.industry, Gastroenterology, Heritability, Twin study, digestive system diseases, language.human_language, Pedigree, Pancreatic Neoplasms, 030220 oncology & carcinogenesis, Cohort, language, 030211 gastroenterology & hepatology, business, Demography, Carcinoma, Pancreatic Ductal
وصف الملف: application/pdf
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المؤلفون: Camilla Schalin-Jäntti, Magnus Kjellman, Farhad Salem, Jon Arne Søreide, Kalle Landerholm, Saara Metso, Tapani Ebeling, Maiken Thyregod Joergensen, Helge L. Waldum, Ulrich Knigge, Henning Grønbæk, Viktor Johanson, Göran Wallin, Fredrik Lindberg, Roger Belusa, Espen Thiis-Evensen, Maria del Pilar Schneider, Halfdan Sorbye, Staffan Welin
المساهمون: Tampere University, Department of Internal medicine, Clinical Medicine
المصدر: Kjellman, M, Knigge, U, Welin, S, Thiis-Evensen, E, Gronbæk, H, Schalin-Jäntti, C, Sorbye, H, Joergensen, M T, Johanson, V, Metso, S, Waldum, H, Søreide, J A, Ebeling, T, Lindberg, F, Landerholm, K, Wallin, G, Salem, F, Schneider, M D P & Belusa, R 2021, ' A plasma protein biomarker strategy for detection of small intestinal neuroendocrine tumors ', Neuroendocrinology, vol. 111, no. 9 . https://doi.org/10.1159/000510483
Neuroendocrinology
Kjellman, M, Knigge, U, Welin, S, Thiis-evensen, E, Gronbaek, H, Schalin-jäntti, C, Sorbye, H, Joergensen, M T, Johanson, V, Metso, S, Waldum, H, Søreide, J A, Ebeling, T, Lindberg, F, Landerholm, K, Wallin, G, Salem, F, Schneider, M D P & Belusa, R 2021, ' A Plasma Protein Biomarker Strategy for Detection of Small Intestinal Neuroendocrine Tumors ', Neuroendocrinology, vol. 111, no. 9, pp. 840-849 . https://doi.org/10.1159/000510483
Kjellman, M, Knigge, U, Welin, S, Thiis-Evensen, E, Gronbaek, H, Schalin-Jäntti, C, Sorbye, H, Joergensen, M T, Johanson, V, Metso, S, Waldum, H, Søreide, J A, Ebeling, T, Lindberg, F, Landerholm, K, Wallin, G, Salem, F, Del Pilar Schneider, M & Belusa, R 2021, ' A Plasma Protein Biomarker Strategy for Detection of Small Intestinal Neuroendocrine Tumors ', Neuroendocrinology, vol. 111, no. 9, pp. 840-849 . https://doi.org/10.1159/000510483مصطلحات موضوعية: medicine.medical_specialty, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Proton-pump inhibitor, Neuroendocrine tumors, 3121 Internal medicine, Gastroenterology, Machine Learning, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Endocrinology, Neuroendocrine tumor, Duodenal Neoplasms, Internal medicine, Diagnosis, Machine learning, medicine, Humans, Stage (cooking), Jejunal Neoplasms, Receiver operating characteristic, biology, Endocrine and Autonomic Systems, business.industry, Kirurgi, Chromogranin A, Biomarker, Interim analysis, medicine.disease, Blood proteins, 3. Good health, Ileal Neoplasms, Neuroendocrine Tumors, 030220 oncology & carcinogenesis, biology.protein, Biomarker (medicine), 030211 gastroenterology & hepatology, Surgery, business, Biomarkers, Research Article
وصف الملف: application/pdf; fulltext
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المؤلفون: Michael Bau Mortensen, Sönke Detlefsen, Ove B. Schaffalitzky de Muckadell, Maiken Thyregod Joergensen, Ming Tan, Klaus Brusgaard, Anne-Marie Gerdes
المصدر: Tan, M, Brusgaard, K, Gerdes, A M, Mortensen, M B, Detlefsen, S, Schaffalitzky de Muckadell, O B & Joergensen, M T 2021, ' Whole genome sequencing identifies rare germline variants enriched in cancer related genes in firstdegree relatives of familial pancreatic cancer patients ', Clinical Genetics, vol. 100, no. 5, pp. 551-562 . https://doi.org/10.1111/cge.14038
Tan, M, Brusgaard, K, Gerdes, A-M A, Mortensen, M B, Detlefsen, S, Schaffalitzky, O B & Jørgensen, M T 2021, ' Whole genome sequencing identifies rare germline variants enriched in cancer related genes in first-degree relatives of familial pancreatic cancer patients ', United European Gastroenterology Journal, vol. 9, no. 8 Suppl., P0836, pp. 751-752 . https://doi.org/10.1002/ueg2.12144
Tan, M, Brusgaard, K, Gerdes, A-M A, Mortensen, M B, Detlefsen, S, Schaffalitzky, O B & Jørgensen, M T 2021, ' Whole genome sequencing identifies rare germline variants enriched in cancer related genes in first degree relatives of familial pancreatic cancer patients ', Clinical Genetics, vol. 100, no. 5, pp. 551-562 . https://doi.org/10.1111/cge.14038مصطلحات موضوعية: Adult, Male, False discovery rate, Genotype, Denmark, familial pancreatic cancer, Biology, Polymorphism, Single Nucleotide, Germline, first-degree relatives, rare germline variants, Germline mutation, Biomarkers, Tumor, Genetics, Humans, Family, Genetic Predisposition to Disease, First-degree relatives, Gene, Alleles, Genetic Association Studies, Germ-Line Mutation, Genetics (clinical), Aged, Genetic association, Aged, 80 and over, Whole genome sequencing, whole genome sequencing, cancer genes, Whole Genome Sequencing, Carcinoma, Family aggregation, Oncogenes, Sequence Analysis, DNA, Middle Aged, Pedigree, Pancreatic Neoplasms, Female
وصف الملف: application/pdf
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المؤلفون: Ming Tan (34506), Klaus Brusgaard (231050), Anne-Marie Gerdes (395264), Michael Bau Mortensen (6502283), Sönke Detlefsen (6502286), Ove B. Schaffalitzky de Muckadell (8120114), Maiken Thyregod Joergensen (11020696)
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المؤلفون: Staffan Welin, Becker Kj, U. Knigge, T. Ström, Magnus Kjellman, Viktor Johanson, Henning Grønbæk, Metso Si, Roger Belusa, Halfdan Sorbye, Espen Thiis-Evensen, Maiken Thyregod Joergensen
المصدر: Neuroendocrinology. 106:1-302
مصطلحات موضوعية: endocrine system, medicine.medical_specialty, biology, Endocrine and Autonomic Systems, business.industry, Endocrinology, Diabetes and Metabolism, Chromogranin A, 030209 endocrinology & metabolism, Kallikrein, Blood proteins, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Endocrinology, Small Intestinal Neuroendocrine Tumor, Internal medicine, biology.protein, Medicine, Biomarker (medicine), business, Somatostatin analog
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المصدر: Pathology International. 67:514-520
مصطلحات موضوعية: Core needle, Endoscopic ultrasound, Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, General Medicine, medicine.disease, digestive system diseases, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Cytology, Biopsy, Medicine, 030211 gastroenterology & hepatology, Radiology, business, Autoimmune pancreatitis
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المؤلفون: Michael Bau Mortensen, Anne-Marie Gerdes, Ming Tan, Klaus Brusgaard, Maiken Thyregod Joergensen, Sönke Detlefsen, Ove B. Schaffalitzky de Muckadell
المصدر: Gastroenterology. 160:S-663
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, Heritability, language.human_language, Danish, Internal medicine, Cohort, Familial Pancreatic Cancer, language, Medicine, business
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المصدر: Pathology international. 67(10)
مصطلحات موضوعية: Adult, Male, Pancreatitis, Biopsy, Fine-Needle, Humans, Female, Middle Aged, Ultrasonography, Interventional, Autoimmune Diseases
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المؤلفون: Anting Liu Carlsen, Niels H. H. Heegaard, Ove B. Schaffalitzky de Muckadell, Maiken Thyregod Joergensen, Steen Knudsen
المصدر: University of Southern Denmark
Carlsen, A L, Joergensen, M T, Knudsen, S, de Muckadell, O B S & Heegaard, N H H 2013, ' Cell-free plasma microRNA in pancreatic ductal adenocarcinoma and disease controls ', Pancreas, vol. 42, no. 7, pp. 1107-1113 . https://doi.org/10.1097/MPA.0b013e318296bb34
Carlsen, A L, Jørgensen, M T, Schaffalitzky de Muckadell, O B, Knudsen, S & Heegaard, N H H 2012, ' Cell-free Plasma microRNA in Pancreatic Ductal Adenocarcinoma and Disease Controls ', International Workshop on small RNA in CIA, København, Denmark, 03/09/2012-04/09/2012 .مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Pancreatic ductal adenocarcinoma, CA-19-9 Antigen, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Cell free, Disease, Cohort Studies, Endocrinology, Internal medicine, microRNA, Gene expression, Biomarkers, Tumor, Internal Medicine, medicine, Carcinoma, Humans, RNA, Neoplasm, Aged, Oligonucleotide Array Sequence Analysis, Cell-Free System, Hepatology, business.industry, Gene Expression Profiling, Case-control study, Middle Aged, medicine.disease, digestive system diseases, Pancreatic Neoplasms, Gene expression profiling, MicroRNAs, Case-Control Studies, Cancer research, Female, business, Carcinoma, Pancreatic Ductal
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المؤلفون: Ove B. Schaffalitzky de Muckadell, Michael Bau Mortensen, Anne-Marie Gerdes, Jan Sørensen, Maiken Thyregod Joergensen
المصدر: Jørgensen, M T, Gerdes, A-M, Sørensen, J, Schaffalitzky de Muckadell, O B & Mortensen, M B 2016, ' Is screening for pancreatic cancer in high-risk groups cost-effective? Experience from a Danish national screening program ', Pancreatology, vol. 16, no. 4, pp. 584-592 . https://doi.org/10.1016/j.pan.2016.03.013
مصطلحات موضوعية: Endoscopic ultrasound, Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Cost-Benefit Analysis, Denmark, Risk Assessment, Danish, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Pancreatic cancer, Internal medicine, medicine, Humans, Mass Screening, Mass screening, Early Detection of Cancer, Aged, Aged, 80 and over, Hereditary pancreatitis, Hepatology, medicine.diagnostic_test, business.industry, Incidence (epidemiology), Incidence, Smoking, Gastroenterology, Middle Aged, medicine.disease, Prognosis, language.human_language, Cardiac surgery, Surgery, Pancreatic Neoplasms, Treatment Outcome, 030220 oncology & carcinogenesis, language, 030211 gastroenterology & hepatology, Female, Risk assessment, business
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المصدر: Joergensen, M T, Heegaard, N H H & Schaffalitzky de Muckadell, O B 2009, ' Comparison of Plasma Tu-M2-PK and CA19-9 in Pancreatic Cancer ', Pancreas, vol. 39, no. 2, pp. 243-247 . https://doi.org/10.1097/MPA.0b013e3181bae8ab
مصطلحات موضوعية: Male, Oncology, medicine.medical_specialty, CA-19-9 Antigen, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Pyruvate Kinase, Sensitivity and Specificity, Gastroenterology, Endocrinology, Cholestasis, Predictive Value of Tests, Internal medicine, Pancreatic cancer, Biomarkers, Tumor, Odds Ratio, Internal Medicine, medicine, Humans, Prospective Studies, Prospective cohort study, Aged, Neoplasm Staging, Tumor marker, Chi-Square Distribution, Hepatology, business.industry, Area under the curve, Middle Aged, Jaundice, medicine.disease, digestive system diseases, Pancreatic Neoplasms, Logistic Models, ROC Curve, Case-Control Studies, Pancreatitis, Female, CA19-9, medicine.symptom, business, Carcinoma, Pancreatic Ductal
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المؤلفون: Anne-Marie Gerdes, Dorthe G. Crüger, Klaus Brusgaard, Maiken Thyregod Joergensen, Ove B. Schaffalitzky de Muckadell
المصدر: Jørgensen, M T, Brusgaard, K, Crüger, D G, Gerdes, A-M & Schaffalitzky de Muckadell, O B 2010, ' Incidence, Prevalence, Etiology, and Prognosis of First-Time Chronic Pancreatitis in Young Patients: A Nationwide Cohort Study ', Digestive Diseases and Sciences, vol. 55, no. 10, pp. 2988-2998 . https://doi.org/10.1007/s10620-009-1118-4
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Pancreatic disease, Adolescent, Pancreatitis, Alcoholic, Physiology, Denmark, Genetic counseling, Comorbidity, Kaplan-Meier Estimate, Gastroenterology, Cohort Studies, Young Adult, Age Distribution, Cause of Death, Pancreatitis, Chronic, Internal medicine, Prevalence, Humans, Medicine, Registries, Sex Distribution, Hereditary pancreatitis, business.industry, Incidence, Incidence (epidemiology), Odds ratio, Prognosis, medicine.disease, Hospitalization, Endocrinology, Acute Disease, Chronic Disease, Cohort, Etiology, Pancreatitis, Exocrine Pancreatic Insufficiency, Female, business
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المؤلفون: Klaus Brusgaard, Anne-Marie Gerdes, Srdan Novovic, Maiken Thyregod Joergensen, Ove B. Schaffalitzky de Muckadell, Mark Berner Hansen, Anders Møller Andersen
المصدر: Jørgensen, M T, Brusgaard, K, Novovic, S, Andersen, A M, Hansen, M B, Gerdes, A-M & Schaffalitzky de Muckadell, O B 2012, ' Is the SPINK1 variant p.N34S overrepresented in patients with acute pancreatitis? ', European journal of gastroenterology & hepatology, vol. 24, no. 3, pp. 309-15 . https://doi.org/10.1097/MEG.0b013e32834ee5e2
مصطلحات موضوعية: Male, medicine.medical_specialty, Pathology, Trypsinogen, Denmark, Population, Gastroenterology, chemistry.chemical_compound, Recurrent pancreatitis, Internal medicine, medicine, Humans, Prospective Studies, education, Prospective cohort study, Aged, education.field_of_study, Hepatology, biology, business.industry, C-reactive protein, Case-control study, Middle Aged, medicine.disease, Prognosis, C-Reactive Protein, chemistry, Pancreatitis, Trypsin Inhibitor, Kazal Pancreatic, Case-Control Studies, Acute Disease, Mutation, biology.protein, Acute pancreatitis, Biological Markers, Female, business, Carrier Proteins, Biomarkers
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المؤلفون: Anne-Marie Gerdes, Péter Hegyi, Andrea Geisz, Maiken Thyregod Joergensen, Miklós Sahin-Tóth, Klaus Brusgaard, Ove B. Schaffalitzky de Muckadell
المصدر: Joergensen, M T, Geisz, A, Brusgaard, K, Schaffalitzky de Muckadell, O B, Peter, H, Gerdes, A M & Sahin-Toth, M 2011, ' Intragenic Duplication A Novel Mutational Mechanism in Hereditary Pancreatitis ', Pancreas, vol. 40, no. 4, pp. 540-546 . https://doi.org/10.1097/MPA.0b013e3182152fdf
مصطلحات موضوعية: Male, Repetitive Sequences, Amino Acid, Trypsinogen, Endocrinology, Diabetes and Metabolism, Denmark, Mutant, Blotting, Western, Biology, medicine.disease_cause, digestive system, Cathepsin B, Article, chemistry.chemical_compound, Endocrinology, Pancreatitis, Chronic, Internal Medicine, medicine, Humans, Trypsin, Amino Acid Sequence, Trypsinogen activation, Pancreatitis, chronic, Repetitive Sequences, Nucleic Acid, Family Health, Mutation, Hereditary pancreatitis, Hepatology, Base Sequence, medicine.disease, Molecular biology, digestive system diseases, Pedigree, Enzyme Activation, HEK293 Cells, chemistry, Biochemistry, Female, medicine.drug
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المؤلفون: Klaus Brusgaard, Maiken Thyregod Joergensen, Dorthe G. Crüger, Ove B. Schaffalitzky de Muckadell, Anne-Marie Gerdes
المصدر: The American journal of gastroenterology. 105(8)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Pediatrics, Pancreatic disease, Genotype, Denmark, Population, Cystic Fibrosis Transmembrane Conductance Regulator, Gastroenterology, Statistics, Nonparametric, Cohort Studies, Population based cohort, Risk Factors, Internal medicine, Epidemiology, medicine, Humans, Trypsin, Poisson Distribution, Registries, education, education.field_of_study, Hereditary pancreatitis, Chi-Square Distribution, Hepatology, business.industry, medicine.disease, Prognosis, Pedigree, Pancreatic Neoplasms, Pancreatitis, Trypsin Inhibitor, Kazal Pancreatic, Mutation, Female, business, Carrier Proteins, Cohort study
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المؤلفون: Bronwyn Kerr, Edyta Niemczyck, John P. Neoptolemos, Frank Ulrich Weiss, Susanna Dodd, Louis Vitone, Jacques Devière, C. Grocock, Richard Charnley, Michael Raraty, William Greenhalf, Robert Sutton, Ove B. Schaffalitzky de Muckadell, Vinciane Rebours, Rudolf W. Ammann, Philippe Lévy, Myriam Delhaye, Philip Burgess, Maiken Thyregod Joergensen, J. Butler, Roger Mountford, Åke Andrén-Sandberg, David C. Whitcomb, Markus M. Lerch, Matthew Harcus
المصدر: Grocock, C J, Rebours, V, Delhaye, M, Andren-Sandberg, A, Weiss, F U, Mountford, R, Harcus, M, Niemczyck, E, Vitone, L, Dodd, S, Joergensen, M T, Ammann, R W, Schaffalitzky de Muckadell, O, Butler, J V, Burgess, P, Kerr, B, Charnley, R, Sutton, R, Raraty, M, Deviere, J, Whitcomb, D, Neoptolemos, J, Levy, P, Lerch, M M & Greenhalf, W 2010, ' The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families ', Gut, vol. 59, pp. 357-363 . https://doi.org/10.1136/gut.2009.186817
مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Heterozygote, Pancreatic disease, Adolescent, Trypsinogen, Cystic Fibrosis Transmembrane Conductance Regulator, Penetrance, Gastroenterology, chemistry.chemical_compound, Young Adult, Pancreatic cancer, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Trypsin, Family history, Age of Onset, Child, Hereditary pancreatitis, business.industry, Infant, Middle Aged, medicine.disease, Neoplasm Proteins, Pedigree, Pancreatic Neoplasms, chemistry, Pancreatitis, Trypsin Inhibitor, Kazal Pancreatic, Child, Preschool, Mutation, Female, Age of onset, business, Carrier Proteins
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المؤلفون: Ove B. Schaffalitzky de Muckadell, Maiken Thyregod Joergensen, Anne-Marie Gerdes, Dorthe G. Crüger, Klaus Brusgaard
المصدر: Joergensen, M, Brusgaard, K, Crüger, D G, Gerdes, A-M & Schaffalitzky de Muckadell, O B 2010, ' Incidence, etiology and prognosis of first-time acute pancreatitis in young patients: a population-based cohort study ', Pancreatology, vol. 10, no. 4, pp. 453-61 . https://doi.org/10.1159/000260666
مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Pediatrics, Endocrinology, Diabetes and Metabolism, Cystic Fibrosis Transmembrane Conductance Regulator, Cohort Studies, Young Adult, Pancreatitis, Chronic, medicine, Humans, Trypsin, Pancreatitis, chronic, skin and connective tissue diseases, Survival rate, Hereditary pancreatitis, Hepatology, business.industry, Incidence (epidemiology), Incidence, Gastroenterology, medicine.disease, Prognosis, Survival Rate, Trypsin Inhibitor, Kazal Pancreatic, Population Surveillance, Acute Disease, Etiology, Pancreatitis, Acute pancreatitis, Female, sense organs, business, Carrier Proteins, Cohort study