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المؤلفون: Asllan Gjinovci, Carmen M. Jimenez Moreno, Claes B. Wollheim, Kai Hui Hu He, Deborah Aeberhard, Fabrizio Thorel, Marion Cornu, Benoit R. Gauthier, Petra I. Lorenzo, Jorge Vallejo Ortega, Pedro Luis Herrera, Thierry Brun, Bernard Thorens, Paolo Meda
المساهمون: European Commission, Swiss National Science Foundation, Juvenile Diabetes Research Foundation International, National Institutes of Health (US), Novo Nordisk Foundation, Junta de Andalucía, Fundación Progreso y Salud
المصدر: Diabetes
Diabetes, Vol. 60, No 6 (2011) pp. 1705-15
Diabetes; Vol 60
Diabetes, vol. 60, no. 6, pp. 1705-1715
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Apoptosis/genetics/physiology, Maf Transcription Factors, Large, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Streptozocin/toxicity, Apoptosis, Polymerase Chain Reaction, Mice, 0302 clinical medicine, Stress, Physiological/physiology, Insulin-Secreting Cells, Proto-Oncogene Proteins c-myc/genetics/metabolism, Insulin, Paired Box Transcription Factors, Glucose Transporter Type 2/genetics/metabolism, Glucose homeostasis, ddc:576.5, Cyclin-Dependent Kinase 4/genetics/metabolism, Homeodomain Proteins/genetics/metabolism, Hyperglycemia/chemically induced/metabolism/prevention & control, Glucose Transporter Type 2, 0303 health sciences, geography.geographical_feature_category, biology, Cytochromes c, Islet, Immunohistochemistry, 3. Good health, Proto-Oncogene Proteins c-bcl-2, Insulin-Secreting Cells/cytology/metabolism, Cytochromes c/genetics/metabolism, medicine.drug, Genetically modified mouse, endocrine system, medicine.medical_specialty, Maf Transcription Factors, Large/genetics/metabolism, Immunoblotting, Mice, Transgenic, 030209 endocrinology & metabolism, Streptozocin, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Stress, Physiological, Internal medicine, Internal Medicine, medicine, Animals, ddc:612, Proto-Oncogene Proteins c-bcl-2/genetics/metabolism, 030304 developmental biology, Homeodomain Proteins, Insulin/genetics/metabolism, geography, Apoptosis/genetics, Apoptosis/physiology, Cyclin-Dependent Kinase 4/genetics, Cyclin-Dependent Kinase 4/metabolism, Cytochromes c/genetics, Cytochromes c/metabolism, Glucose Transporter Type 2/genetics, Glucose Transporter Type 2/metabolism, Homeodomain Proteins/genetics, Homeodomain Proteins/metabolism, Hyperglycemia/chemically induced, Hyperglycemia/metabolism, Insulin/genetics, Insulin/metabolism, Insulin-Secreting Cells/cytology, Insulin-Secreting Cells/metabolism, Maf Transcription Factors, Large/genetics, Maf Transcription Factors, Large/metabolism, Paired Box Transcription Factors/genetics, Paired Box Transcription Factors/metabolism, Proto-Oncogene Proteins c-bcl-2/genetics, Proto-Oncogene Proteins c-bcl-2/metabolism, Proto-Oncogene Proteins c-myc/genetics, Proto-Oncogene Proteins c-myc/metabolism, Cyclin-Dependent Kinase 4, Streptozotocin, Paired Box Transcription Factors/genetics/metabolism, Endocrinology, Islet Studies, Hyperglycemia, biology.protein, PAX4, GLUT2
وصف الملف: application/pdf
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المؤلفون: Mark A. Magnuson, Weiping Yuan, Klaus H. Kaestner, Brandon L. Taylor, Jacqueline R. Benthuysen, Catherine Lee May, Pedro Luis Herrera, Fabrizio Thorel, Jingxuan Liu, Ashleigh E. Schaffer, Yang Jiao, Maike Sander
المصدر: PLoS Genetics, Vol 9, Iss 1, p e1003274 (2013)
PLoS Genetics
PLOS Genetics, Vol. 9, No 1 (2013) P. e1003274مصطلحات موضوعية: Cancer Research, Maf Transcription Factors, Large, Pancreas/cytology, Cellular differentiation, Cell- and Tissue-Based Therapy, Enteroendocrine cell, Transcription Factors/genetics/metabolism, Cell Fate Determination, Alpha cell, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Insulin, ddc:576.5, Gene Regulatory Networks, Endocrine Cells/cytology/secretion, Homeodomain Proteins/genetics/metabolism, Genetics (clinical), Genetics, 0303 health sciences, Stem Cells, Gene Expression Regulation, Developmental, Cell Differentiation, Tissue Therapy, Insulin/genetics/secretion, Cell biology, medicine.anatomical_structure, embryonic structures, PDX1, Beta cell, Stem cell, Pancreas, Research Article, animal structures, Maf Transcription Factors, Large/genetics/metabolism, lcsh:QH426-470, Cell Differentiation/genetics, Trans-Activators/genetics/metabolism, Biology, Molecular Genetics, 03 medical and health sciences, medicine, Animals, Humans, Cell Lineage, Gene Regulation, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Homeodomain Proteins, Embryonic stem cell, Insulin-Secreting Cells/cytology/metabolism/secretion, lcsh:Genetics, Trans-Activators, Endocrine Cells, Gene Function, 030217 neurology & neurosurgery, Transcription Factors, Developmental Biology