المؤلفون: Aline Barth, Caroline R. Perry, Shaila Shabbir, Maciej J. Zamek‐Gliszczynski, Sebin Thomas, Etienne F. Dumont, Darin B. Brimhall, Dung Nguyen, Meenakshi Srinivasan, Brandon Swift

المصدر: Clinical and Translational Science, Vol 16, Iss 4, Pp 647-661 (2023)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

URL الوصول: https://doaj.org/article/eb09ea58f44a4c3d9b5034a04a6ca60a

المؤلفون: Tatsuki Mochizuki, Yasunori Aoki, Takashi Yoshikado, Kenta Yoshida, Yurong Lai, Hideki Hirabayashi, Yoshiyuki Yamaura, Kevin Rockich, Kunal Taskar, Tadayuki Takashima, Xiaoyan Chu, Maciej J. Zamek‐Gliszczynski, Jialin Mao, Kazuya Maeda, Kenichi Furihata, Yuichi Sugiyama, Hiroyuki Kusuhara

المصدر: Clinical and Translational Science, Vol 15, Iss 6, Pp 1519-1531 (2022)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

URL الوصول: https://doaj.org/article/3aee0ecb9abb40628d9f8c6327bcb5a4

المؤلفون: Maciej J, Zamek-Gliszczynski, Vishal, Sangha, Hong, Shen, Bo, Feng, Matthias B, Wittwer, Manthena V S, Varma, Xiaomin, Liang, Yuichi, Sugiyama, Lei, Zhang, Reina, Bendayan

المصدر: Clinical Pharmacology & Therapeutics. 112:485-500

مصطلحات موضوعية: Pharmacology, Folic Acid, Glucuronides, Humans, Membrane Transport Proteins, Biological Transport, Pharmacology (medical), Prospective Studies, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cb020495f32efc5dc9257792eb6889
https://doi.org/10.1002/cpt.2644

المؤلفون: Chu Xiaoyan, Hideki Hirabayashi, Kevin Rockich, Kunal Taskar, Kusuhara Hiroyuki, Lai Yurong, Maciej J. Zamek-Gliszczynski, Rockich Kevin, Tadayuki Takashima, Taskar Kunal, Tatsuki Mochizuki, Xiaoyan Chu, Yoshida Kenta, Yoshiyuki Yamaura, Yuichi Sugiyama, Yurong Lai, Zamek-Gliszczynski Maciej J., 吉田 健太, 山浦 由之, 平林 英樹, 望月 達貴, 杉山 雄一, 楠原 洋之, 高島 忠之

المصدر: Annual Scientific Meeting of The Japanese Society of Clinical Pharmacology and Therapeutics. 2021, :1-1

المؤلفون: Tatsuki Mochizuki, Maciej J. Zamek‐Gliszczynski, Kenta Yoshida, Jialin Mao, Kunal Taskar, Hideki Hirabayashi, Xiaoyan Chu, Yurong Lai, Tadayuki Takashima, Kevin Rockich, Yoshiyuki Yamaura, Kaku Fujiwara, Tadahaya Mizuno, Kazuya Maeda, Kenichi Furihata, Yuichi Sugiyama, Hiroyuki Kusuhara

المصدر: Clinical Pharmacology & Therapeutics. 111:1315-1323

مصطلحات موضوعية: Pharmacology, Solute Carrier Organic Anion Transporter Family Member 1B3, Liver-Specific Organic Anion Transporter 1, Cyclosporine, Humans, Organic Anion Transporters, Valsartan, Drug Interactions, Pharmacology (medical), Rosuvastatin Calcium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe49ca943b27de4a6141c77e320bebb6
https://doi.org/10.1002/cpt.2584

المؤلفون: Liang Zeng Yan, Kelly M. Credille, John A. Wijsman, Maciej J. Zamek-Gliszczynski, Yu-Hua Hui, Qi Chen, Mark T. Uhlik, Julie Stewart, Wendy Gough, Lisa M. Kays, Donald Paul, Xiaoyi Zhang, Sheng-Bin Peng

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257d2da280ca00412cf61dc0b403427c
https://doi.org/10.1158/1535-7163.22503555.v1

المؤلفون: Brandon Swift, Lee Crossman, Graeme Young, Robin L. O'Connor-Semmes, Megan M. McLaughlin, David Kenworthy, David A. Bershas, Matthew Allinder, Jill L. Pirhalla, Mitesh Sanghvi, Maciej J. Zamek-Gliszczynski, Karl M. Thorpe, Jeremy Dennison, Jennypher Mudunuru, Adrian Pereira

المصدر: Drug Metabolism and Disposition. 49:1109-1117

مصطلحات موضوعية: Pharmacology, CYP3A4, Chemistry, Pharmaceutical Science, medicine.disease, Intestinal absorption, Bioavailability, Excretion, Renal Elimination, Pharmacokinetics, medicine, Cholestatic pruritus, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3d996ca482b164fc913af14a3e88ca4f
https://doi.org/10.1124/dmd.121.000595

المؤلفون: Justin D. Lutz, Yuichi Sugiyama, Kim L. R. Brouwer, Caroline A. Lee, Sibylle Neuhoff, Kunal S Taskar, Xinning Yang, Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Mary F. Paine, Aleksandra Galetin, Yurong Lai, Mitesh Patel

المصدر: Clin Pharmacol Ther

مصطلحات موضوعية: Drug, media_common.quotation_subject, ATP-binding cassette transporter, Context (language use), Pharmacology, 030226 pharmacology & pharmacy, Article, 03 medical and health sciences, 0302 clinical medicine, Drug Development, Humans, Medicine, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Dosing, media_common, Pregnane X receptor, Liver-Specific Organic Anion Transporter 1, Mechanism (biology), business.industry, Membrane Transport Proteins, Biological Transport, Transporter, Intestines, Liver, Drug development, 030220 oncology & carcinogenesis, Hepatocytes, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b099be27759b74c7d4f44d4fb3c9ee
https://doi.org/10.1002/cpt.1916

المؤلفون: Maciej J, Zamek-Gliszczynski, David, Kenworthy, David A, Bershas, Mitesh, Sanghvi, Adrian I, Pereira, Jennypher, Mudunuru, Lee, Crossman, Jill L, Pirhalla, Karl M, Thorpe, Jeremy M T J, Dennison, Megan M, McLaughlin, Matthew, Allinder, Brandon, Swift, Robin L, O'Connor-Semmes, Graeme C, Young

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 49(12)

مصطلحات موضوعية: Adult, Male, Membrane Glycoproteins, Metabolic Clearance Rate, Thiazepines, Administration, Oral, Biological Availability, Healthy Volunteers, Hepatobiliary Elimination, Methylamines, Renal Elimination, Treatment Outcome, Gastrointestinal Agents, Intestinal Absorption, Humans, Administration, Intravenous, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6d3fb15060f3d798f11b6424b7918a34
https://pubmed.ncbi.nlm.nih.gov/34625435

المؤلفون: Friedrich B M Reinhard, Anne T. Nies, Gerard Drewes, Melissa S Unger, David Weigt, Maciej J. Zamek-Gliszczynski, Sandra Schulz, Thomas Enzlein, Carsten Hopf, Matthias Schwab, Lena Schumacher

المصدر: Analytical chemistry. 92(17)

مصطلحات موضوعية: Chemistry, Drug discovery, Cell, Substrate (chemistry), Organic Anion Transporters, Transporter, Biological Transport, Analytical Chemistry, Solute carrier family, Matrix (chemical analysis), medicine.anatomical_structure, Pharmacokinetics, Biochemistry, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, medicine, Humans, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e648759575120a13b2ba2bb04db73f1
https://pubmed.ncbi.nlm.nih.gov/32867487

المؤلفون: Aleksandra Galetin, Donald J. Tweedie, Lei Zhang, Maciej J. Zamek-Gliszczynski, Xiaoyan Chu

المصدر: Chu, X, Galetin, A, Zamek-gliszczynski, M J, Zhang, L & Tweedie, D J 2018, ' Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition ', Clinical Pharmacology & Therapeutics, vol. 104, no. 5, pp. 788-792 . https://doi.org/10.1002/cpt.2018.104.issue-5

مصطلحات موضوعية: Digoxin, ATP-binding cassette transporter, Pharmacology, Risk Assessment, 030226 pharmacology & pharmacy, Dabigatran, 03 medical and health sciences, 0302 clinical medicine, Drug Stability, Biotransformation, medicine, Humans, Drug Interactions, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, business.industry, Intestinal Absorption, Caco-2, 030220 oncology & carcinogenesis, Caco-2 Cells, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4835229ea3e9726b7d61091f722da5dd
https://doi.org/10.1002/cpt.1213

المؤلفون: Harma Ellens, Maciej J. Zamek-Gliszczynski, Mitesh Patel, Marta Johnson, Caroline Sychterz, Gareth J. Lewis, Joseph W. Polli, Cory A Watson

المصدر: Journal of Pharmacology and Experimental Therapeutics. 366:37-45

مصطلحات موضوعية: Male, Pharmacology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Animals, Humans, Tissue Distribution, Biliary Tract, Atovaquone, Chemistry, Multidrug resistance-associated protein 2, Membrane Transport Proteins, Rifamycin, Biological Transport, In vitro, Rats, HEK293 Cells, medicine.anatomical_structure, Liver, Solubility, 030220 oncology & carcinogenesis, Hepatocyte, Knockout mouse, Molecular Medicine, Efflux, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d3c7d17df8690608b18392c303cec5
https://doi.org/10.1124/jpet.117.247254

المؤلفون: Gary M. Pollack, Kim L. R. Brouwer, S. Bridges, Peijin Zhang, Nita J. Patel, Thomas J. Raub, Xianbin Tian, Jun Li, Maciej J. Zamek-gliszczynski

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/51/9/3230.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.517.398; http://aac.asm.org/content/51/9/3230.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.517.398
http://aac.asm.org/content/51/9/3230.full.pdf

المؤلفون: Ken-Ichi Nezasa, Xianbin Tian, Maciej J Zamek-Gliszczynski, Nita J Patel, Thomas J Raub, Kim L R Brouwer

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dmd.aspetjournals.org/content/dmd/34/4/718.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1052.1525; http://dmd.aspetjournals.org/content/dmd/34/4/718.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1052.1525
http://dmd.aspetjournals.org/content/dmd/34/4/718.full.pdf

المؤلفون: Daniel C. Kemp, Maciej J. Zamek-gliszczynski, Kim L. R. Brouwer

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://toxsci.oxfordjournals.org/content/83/2/207.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.492.2136; http://toxsci.oxfordjournals.org/content/83/2/207.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.492.2136
http://toxsci.oxfordjournals.org/content/83/2/207.full.pdf

المؤلفون: Maciej J. Zamek-Gliszczynski, Melissa S Unger, Matthias Schwab, Gerard Drewes, Jennypher Mudunuru, Carsten Hopf, Friedrich B M Reinhard, Anne T. Nies

المصدر: Molecular Pharmaceutics.

مصطلحات موضوعية: Drug, Cell Survival, media_common.quotation_subject, Drug Evaluation, Preclinical, Organic Anion Transporters, Pharmaceutical Science, 02 engineering and technology, Dibromofluorescein, Pharmacology, Transfection, 030226 pharmacology & pharmacy, Incubation period, Erlotinib Hydrochloride, Inhibitory Concentration 50, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Drug Discovery, Ic50 values, Humans, Medicine, Drug Interactions, Intestinal Mucosa, IC50, media_common, Drug disposition, business.industry, Biological Transport, Transporter, Fluoresceins, 021001 nanoscience & nanotechnology, HEK293 Cells, Liver, Molecular Medicine, 0210 nano-technology, business, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4034c9f3a0d04a678186e4075523c7
https://doi.org/10.1021/acs.molpharmaceut.9b00897

المؤلفون: Kunal S Taskar, Maciej J. Zamek-Gliszczynski, Jane Huang, Xuexiang Zhang, Jian-Lu Chen, Jennypher Mudunuru, Yewei Du, Yong Huang, Elizabeth H Romach

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 47(8)

مصطلحات موضوعية: Pyridones, Pharmaceutical Science, HIV Infections, Pharmacology, Folic Acid Deficiency, 030226 pharmacology & pharmacy, Risk Assessment, Piperazines, Madin Darby Canine Kidney Cells, 03 medical and health sciences, chemistry.chemical_compound, Reduced Folate Carrier Protein, 0302 clinical medicine, Cabotegravir, Dogs, Folic Acid, Pregnancy, Oxazines, medicine, Animals, Humans, Folate Receptor 1, HIV Integrase Inhibitors, Neural Tube Defects, Maternal-Fetal Exchange, Enzyme Assays, Valproic Acid, biology, Bictegravir, Elvitegravir, business.industry, Incidence, Infant, Newborn, Raltegravir, Endocytosis, Integrase, chemistry, Folate receptor, Maternal Exposure, 030220 oncology & carcinogenesis, Dolutegravir, biology.protein, Female, business, Heterocyclic Compounds, 3-Ring, Proton-Coupled Folate Transporter, medicine.drug, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f578dd7a73e2ca29a45839eebb135d1
https://pubmed.ncbi.nlm.nih.gov/31167838

المؤلفون: Xianbin Tian, Maciej J. Zamek-gliszczynski, Jun Li, Arlene S. Bridges, Ken-ichi Nezasa, Nita J. Patel, Thomas J. Raub, Kim L. R. Brouwer

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dmd.aspetjournals.org/content/36/1/61.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.614.7246; http://dmd.aspetjournals.org/content/36/1/61.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.614.7246
http://dmd.aspetjournals.org/content/36/1/61.full.pdf

المؤلفون: Maciej J. Zamek-Gliszczynski, Elizabeth H Romach, J C Bloomer, Lorraine M. Posobiec, Dinesh Stanislaus

المصدر: EBioMedicine, Vol 66, Iss, Pp 103335-(2021)

مصطلحات موضوعية: Medicine (General), Pregnancy, Fetus, Pediatrics, medicine.medical_specialty, Letter to the editor, business.industry, MEDLINE, General Medicine, medicine.disease, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, R5-920, chemistry, Dolutegravir, Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec30159f2712a46563c4c9b46beb84d
https://doi.org/10.1016/j.ebiom.2021.103335

المؤلفون: S. L. Johnson, X. Yao, L. Webster, Jiang Lin, Maciej J. Zamek-Gliszczynski, Ann Louise Walker, Derek J. Nunez, D. S. Gillmor, S. Krug-Gourley, P. Zuo

المصدر: Diabetes, Obesity and Metabolism. 18:654-662

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, Gastrointestinal Diseases, Thiazepines, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Insulin, Medicine, Cross-Over Studies, Symporters, Area under the curve, Fasting, Middle Aged, Metformin, Treatment Outcome, Area Under Curve, Sitagliptin, Female, 030211 gastroenterology & hepatology, medicine.drug, Adult, Diarrhea, medicine.medical_specialty, Organic Anion Transporters, Sodium-Dependent, Drug Administration Schedule, Bile Acids and Salts, Methylamines, 03 medical and health sciences, Double-Blind Method, Internal medicine, Internal Medicine, Humans, Hypoglycemic Agents, Apolipoproteins B, Triglyceride, business.industry, Cholesterol, Cholesterol, LDL, Lipid Metabolism, medicine.disease, Crossover study, 030104 developmental biology, Diabetes Mellitus, Type 2, chemistry, Pharmacodynamics, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7dfe91b3d64238f4709549a5789ba9
https://doi.org/10.1111/dom.12656