المؤلفون: Hirata, Amanda S, Rezende-Teixeira, Paula, Machado-Neto, João Agostinho, Jimenez, Paula C, Clair, James J La, Fenical, William, Costa-Lotufo, Leticia V

المصدر: Molecules (Basel, Switzerland). 26(23)

مصطلحات موضوعية: Cell Line, Tumor, Humans, Melanoma, Quinones, GTP Phosphohydrolases, Proto-Oncogene Proteins B-raf, Serine, Membrane Proteins, Antineoplastic Agents, Apoptosis, Mutation, Autophagy, Drug Discovery, antitumor agent, apoptosis, autophagy, dermcidin, drug discovery, marine pharmacology, natural products, Cancer, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Medicinal and Biomolecular Chemistry, Organic Chemistry, Theoretical and Computational Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9034947x
https://escholarship.org/content/qt9034947x/qt9034947x.pdf

المؤلفون: Carvalho, Maria Fernanda Lopes, Calicchio, Carolina Santana, de Almeida, Bruna Oliveira, de Miranda, Livia Bassani Lins, Lipreri da Silva, Jean Carlos, Lima, Keli, Machado-Neto, João Agostinho

المساهمون: State of Sao Paulo Research Foundation, Coordination of Higher Education Personnel Improvement

المصدر: Clinics ; volume 79, page 100422 ; ISSN 1807-5932

الاتاحة: https://doi.org/10.1016/j.clinsp.2024.100422
https://api.elsevier.com/content/article/PII:S1807593224000991?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1807593224000991?httpAccept=text/plain

المؤلفون: Lima, Keli, Nogueira, Frederico Lisboa, Cipelli, Marcella, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego Antonio, da Silva, Wellington Fernandes, Cavaglieri, Rita de Cássia, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Câmara, Niels Olsen Saraiva, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

المصدر: Lima , K , Nogueira , F L , Cipelli , M , Carvalho , M F L , Pereira-Martins , D A , da Silva , W F , Cavaglieri , R D C , Nardinelli , L , Leal , A D M , Velloso , E D R P , Bendit , I , Câmara , N O S , Schuringa , J J , Machado-Neto , J A & Rego , E M 2024 , ' Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia ' , European Journal of Pharmacology , vol. ....

مصطلحات موضوعية: Acute lymphoblastic leukemia, Antineoplastic agents, Drug development, Phosphatidylinositol 5-phosphate 4-kinase type 2

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/7f853e21-ff17-4501-ab77-b34ab631e59c
https://research.rug.nl/en/publications/7f853e21-ff17-4501-ab77-b34ab631e59c
https://doi.org/10.1016/j.ejphar.2024.176723
https://pure.rug.nl/ws/files/1111228370/1-s2.0-S0014299924004114-main.pdf
http://www.scopus.com/inward/record.url?scp=85195414867&partnerID=8YFLogxK

المؤلفون: Carlos, Jorge Antonio Elias Godoy, Lima, Keli, Rego, Eduardo Magalhães, Costa-Lotufo, Leticia Veras, Machado-Neto, João Agostinho

المساهمون: National Council for Scientific and Technological Development, State of Sao Paulo Research Foundation, Coordination of Higher Education Personnel Improvement

المصدر: Hematology, Transfusion and Cell Therapy ; volume 46, page S217-S227 ; ISSN 2531-1379

الاتاحة: https://doi.org/10.1016/j.htct.2024.05.012
https://api.elsevier.com/content/article/PII:S2531137924003092?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2531137924003092?httpAccept=text/plain

المؤلفون: Lima, Keli, Rojas, César Alexander Ortiz, Nogueira, Frederico Lisboa, da Silva, Wellington Fernandes, Cavaglieri, Rita de Cássia, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Alencar, Alvaro, Mullighan, Charles G., Machado‐Neto, João Agostinho, Rego, Eduardo Magalhães

المساهمون: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

المصدر: eJHaem ; volume 5, issue 6, page 1366-1369 ; ISSN 2688-6146 2688-6146

الاتاحة: https://doi.org/10.1002/jha2.1030
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jha2.1030

المؤلفون: Lipreri da Silva, Jean Carlos, Coelho-Silva, Juan Luiz, Vicari, Hugo Passos, Lima, Keli, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

المساهمون: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

المصدر: Hematology, Transfusion and Cell Therapy ; volume 46, issue 1, page 101-105 ; ISSN 2531-1379

الاتاحة: http://dx.doi.org/10.1016/j.htct.2023.06.004
https://api.elsevier.com/content/article/PII:S253113792300144X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S253113792300144X?httpAccept=text/plain

المؤلفون: de Queiroz, Gustavo Nery, Lima, Keli, de Miranda, Livia Bassani Lins, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

المساهمون: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Fundação de Amparo à Pesquisa do Estado de São Paulo

المصدر: Hematology, Transfusion and Cell Therapy ; volume 46, page S112-S121 ; ISSN 2531-1379

الاتاحة: https://doi.org/10.1016/j.htct.2024.02.017
https://api.elsevier.com/content/article/PII:S2531137924000622?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2531137924000622?httpAccept=text/plain

المؤلفون: do Nascimento, Mariane Cristina, Pereira-Martins, Diego A., Machado-Neto, João Agostinho, Rego, Eduardo M.

المساهمون: Conselho Nacional de Desenvolvimento Científico e Tecnológico, State of Sao Paulo Research Foundation

المصدر: Hematology, Transfusion and Cell Therapy ; volume 46, page S48-S52 ; ISSN 2531-1379

الاتاحة: https://doi.org/10.1016/j.htct.2023.10.007
https://api.elsevier.com/content/article/PII:S2531137923026020?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2531137923026020?httpAccept=text/plain

المؤلفون: Lipreri da Silva, Jean Carlos, Lima, Keli, Ede, Benjamin, Lazarini, Mariana, Vicari, Hugo Passos, Nogueira, Frederico Lisboa, Clayton, Natasha S., Pinnell, Katy, Silva, Wellington Fernandes da, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Costa-Lotufo, Leticia Veras, Rego, Eduardo Magalhães, Ridley, Anne J., Machado-Neto, João Agostinho

المصدر: Lipreri da Silva , J C , Lima , K , Ede , B , Lazarini , M , Vicari , H P , Nogueira , F L , Clayton , N S , Pinnell , K , Silva , W F D , Velloso , E D R P , Bendit , I , Costa-Lotufo , L V , Rego , E M , Ridley , A J & Machado-Neto , J A 2025 , ' Pharmacological inhibition of ezrin reduces proliferative and invasive phenotype in acute lymphoblastic leukemia cells ' , European Journal of Pharmacology , vol. ....

الاتاحة: https://hdl.handle.net/1983/a28a9609-68f7-493b-b722-da05fe0ce375
https://research-information.bris.ac.uk/en/publications/a28a9609-68f7-493b-b722-da05fe0ce375
https://doi.org/10.1016/j.ejphar.2024.177161

المؤلفون: Sánchez-Mendoza, Silvia Elena, de Deus-Wagatsuma, Virginia Mara, do Nascimento, Mariane Cristina, Lima, Keli, Machado-Neto, João Agostinho, Djavaheri-Mergny, Mojgan, Rego, Eduardo Magalhães

المصدر: Annals of Hematology; Dec2024, Vol. 103 Issue 12, p5405-5416, 12p

المؤلفون: Machado Neto, João Agostinho, 1987

Thesis Advisors: UNIVERSIDADE ESTADUAL DE CAMPINAS, Saad, Sara Teresinha Olalla, 1956, Traina, Fabiola, Rego, Eduardo Magalhães, Panepucci, Rodrigo Alexandre, Vassallo, Jose, Yunes, José Andrés

المصدر: Repositório Institucional da UnicampUniversidade Estadual de CampinasUNICAMP.

مصطلحات موضوعية: Leucemia, Hematopoese, Migração, Proliferação celular, Transdução de sinal, Acute leukemia, Hematopoiesis, Migration, Cell proliferation, Signal transduction

وصف الملف: 126 p. : il.; application/pdf

الاتاحة: http://repositorio.unicamp.br/jspui/handle/REPOSIP/309799

المؤلفون: Lima, Keli, Lopes, Lucia Rossetti, Machado-Neto, João Agostinho

المصدر: Hematology, Transfusion and Cell Therapy. December 2021 43(4)

مصطلحات موضوعية: Myeloproliferative neoplasms, DUOXes, Redox signaling, NADPH oxidase, Ruxolitinib

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2531-13792021000400430

المؤلفون: Lima, Keli, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego Antonio, Nogueira, Frederico Lisboa, de Miranda, Lívia Bassani Lins, Nascimento, Mariane Cristina do, Cavaglieri, Rita de Cássia, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

المصدر: Lima , K , Carvalho , M F L , Pereira-Martins , D A , Nogueira , F L , de Miranda , L B L , Nascimento , M C D , Cavaglieri , R D C , Schuringa , J J , Machado-Neto , J A & Rego , E M 2023 , ' Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia ' , International Journal of Molecular Sciences , vol. 24 , no. 23 , 16899 . https://doi.org/10.3390/ijms242316899

مصطلحات موضوعية: acute myeloid leukemia, phosphatidylinositol-5-phosphate 4-kinase type 2, THZ-P1-2, venetoclax

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/801ed981-9fa7-438b-a9e9-8e0f18dfc0c3
https://research.rug.nl/en/publications/801ed981-9fa7-438b-a9e9-8e0f18dfc0c3
https://doi.org/10.3390/ijms242316899
https://pure.rug.nl/ws/files/907482231/ijms-24-16899.pdf
http://www.scopus.com/inward/record.url?scp=85179362283&partnerID=8YFLogxK

المؤلفون: Lazarini, Mariana, Assis-Mendonça, Guilherme Rossi, Machado-Neto, João Agostinho, Latuf-Filho, Paulo, Bezerra, Stephania Martins, Vieira, Karla Priscila, Saad, Sara Teresinha Olalla

المساهمون: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação de Amparo à Pesquisa do Estado de São Paulo

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ; volume 1870, issue 4, page 119439 ; ISSN 0167-4889

الاتاحة: http://dx.doi.org/10.1016/j.bbamcr.2023.119439
https://api.elsevier.com/content/article/PII:S0167488923000101?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0167488923000101?httpAccept=text/plain

المؤلفون: Carvalho, Maria Fernanda Lopes, de Almeida, Bruna Oliveira, Bueno, Maura Lima Pereira, Vicari, Hugo Passos, Lima, Keli, Rego, Eduardo Magalhães, Roversi, Fernanda Marconi, Machado-Neto, João Agostinho

المساهمون: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

المصدر: Hematology, Transfusion and Cell Therapy ; ISSN 2531-1379

الاتاحة: http://dx.doi.org/10.1016/j.htct.2023.11.007
https://api.elsevier.com/content/article/PII:S253113792302607X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S253113792302607X?httpAccept=text/plain

المؤلفون: Machado Neto, João Agostinho, 1987

Thesis Advisors: UNIVERSIDADE ESTADUAL DE CAMPINAS, Saad, Sara Teresinha Olalla, 1956, Traina, Fabiola, Carvalho, Carla Roberta de Oliveira, Pagnano, Katia Borgia Barbosa

المصدر: Repositório Institucional da UnicampUniversidade Estadual de CampinasUNICAMP.

مصطلحات موضوعية: Leucemia mielóide crônica, Leucemia aguda, Hematopoese, Proliferação celular, Chronic myeloid leukemia, Acute leukemia, Hematopoiesis, Cell proliferation

وصف الملف: 172 p. : il.; application/pdf

الاتاحة: http://repositorio.unicamp.br/jspui/handle/REPOSIP/309256

المؤلفون: Santos de Macedo, Brunno Gilberto, Albuquerque de Melo, Manuela, Pereira-Martins, Diego Antonio, Machado-Neto, João Agostinho, Traina, Fabíola

المصدر: Scientific Reports; 10/12/2024, Vol. 14 Issue 1, p1-10, 10p

مصطلحات موضوعية: ACUTE myeloid leukemia, INFLAMMASOMES, DRUG resistance, AUTOPHAGY, SORAFENIB

المؤلفون: Porto-Soares, Moysés Antonio, Oliveira, Rafael Daltro de, Cortopassi, Gabriel Macedo, Machado-Neto, João Agostinho, Palma, Leonardo Carvalho, Figueiredo-Pontes, Lorena Lobo de

المصدر: Hematology, Transfusion and Cell Therapy. September 2020 42(3)

مصطلحات موضوعية: Myeloproliferative disorders, Primary myelofibrosis, Thrombocythemia, essential, Polycythemia vera, Developing country

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2531-13792020000300238

المؤلفون: Lima, Keli, Pereira-Martins, Diego Antonio, de Miranda, Lívia Bassani Lins, Coelho-Silva, Juan Luiz, Leandro, Giovana da Silva, Weinhäuser, Isabel, Cavaglieri, Rita de Cássia, Leal, Aline de Medeiros, da Silva, Wellington Fernandes, Lange, Ana Paula Alencar de Lima, Velloso, Elvira Deolinda Rodrigues Pereira, Griessinger, Emmanuel, Hilberink, Jacobien R., Ammatuna, Emanuele, Huls, Gerwin, Schuringa, Jan Jacob, Rego, Eduardo Magalhães, Machado-Neto, João Agostinho

المصدر: Lima , K , Pereira-Martins , D A , de Miranda , L B L , Coelho-Silva , J L , Leandro , G D S , Weinhäuser , I , Cavaglieri , R D C , Leal , A D M , da Silva , W F , Lange , A P A D L , Velloso , E D R P , Griessinger , E , Hilberink , J R , Ammatuna , E , Huls , G , Schuringa , J J , Rego , E M & Machado-Neto , J A 2022 , ' The ....

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/2b9f1889-561f-45c9-8aed-a15c62278174
https://research.rug.nl/en/publications/2b9f1889-561f-45c9-8aed-a15c62278174
https://doi.org/10.1038/s41408-022-00747-w
https://pure.rug.nl/ws/files/256596679/The_PIP4K2_inhibitor_THZ_P1_2_exhibits_antileukemia_activity_by_disruption_of_mitochondrial_homeostasis_and_autophagy.pdf
http://www.scopus.com/inward/record.url?scp=85141649030&partnerID=8YFLogxK

المؤلفون: de Miranda, Lívia Bassani Lins, Lima, Keli, Coelho-Silva, Juan Luiz, Traina, Fabiola, Kobayashi, Susumu S., Machado-Neto, João Agostinho

المساهمون: Fundação de Amparo à Pesquisa do Estado de São Paulo, U.S. National Institution of Health, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

المصدر: Scientific Reports ; volume 12, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-022-21419-6
https://www.nature.com/articles/s41598-022-21419-6.pdf
https://www.nature.com/articles/s41598-022-21419-6