المؤلفون: Maarke J.E. Roelofs, A. Roberto Temming, Aldert H. Piersma, Martin van den Berg, Majorie B.M. van Duursen

المصدر: Toxicology Reports, Vol 1, Iss C, Pp 271-283 (2014)

مصطلحات موضوعية: Androgen receptor (AR), Conazole fungicides, Endocrine disrupting chemicals (EDCs), MA-10 Leydig cells, Spermatogenesis, Testosterone (T), Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750014000262; https://doaj.org/toc/2214-7500

URL الوصول: https://doaj.org/article/cef77bcf879e4228a22242c1696d420f

المؤلفون: Maarke J.E. Roelofs, A. Roberto Temming, Aldert H. Piersma, Martin van den Berg, Majorie B.M. van Duursen

المصدر: Toxicology Reports, Vol 3, Iss , Pp 784- (2016)

مصطلحات موضوعية: Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750016300695; https://doaj.org/toc/2214-7500

URL الوصول: https://doaj.org/article/17d3d1497e584362a0b79c304b592749

المؤلفون: Majorie B.M. van Duursen, Maarke J.E. Roelofs, Martin van den Berg, Aldert H. Piersma, A. Roberto Temming

المصدر: Toxicology Reports, Vol 3, Iss, Pp 784-(2016)
Toxicology Reports

مصطلحات موضوعية: medicine.medical_specialty, Leydig cell, Health, Toxicology and Mutagenesis, Biology, Toxicology, Article, In vitro, Androgen receptor, Fungicide, Testosterone Secretion, medicine.anatomical_structure, Endocrinology, lcsh:RA1190-1270, Internal medicine, medicine, lcsh:Toxicology. Poisons

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a53421476130b4b6af69a637e91bfb
http://www.sciencedirect.com/science/article/pii/S2214750016300695

المؤلفون: den Berg Martin van, Rosalinde Masereeuw, Aldert H. Piersma, Anita C A Dankers, Frans G. M. Russel, Maarke J.E. Roelofs, Duursen Majorie B M van

المصدر: Endocrine Abstracts.

مصطلحات موضوعية: medicine.anatomical_structure, Leydig cell, Chemistry, medicine, Endocrine system, Transporter, ATP-binding cassette transporter, Cell biology, Blood–testis barrier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3587dfbca8b6c77af19177f9a170c374
https://doi.org/10.1530/endoabs.32.p644

المؤلفون: Sieto Bosgra, Aldert H. Piersma, Frederik Uibel, Maarke J.E. Roelofs, B. van der Burg, E.D. Kroese, B. M. A. van Vugt-Lussenburg, Lydia R.A. Jonker, Michael Schwarz, Sjors H.W. Schulpen, Joost Westerhout, Sanne A.B. Hermsen, S.C. van der Linden, Andre Wolterbeek, M.B.M. van Duursen, Hai-Yen Man

المساهمون: Promovendi ODB, Toxicogenomics, RS: GROW - School for Oncology and Reproduction

المصدر: Reproductive Toxicology, 38, 53-64
Reproductive Toxicology, 38, 53-64. Elsevier Inc.

مصطلحات موضوعية: Battery (electricity), Alternative assay, Receptors, Steroid, Embryo, Nonmammalian, In vitro test, Biomedical Innovation, Computational biology, Biology, Pharmacology, Animal Testing Alternatives, Toxicology, Embryonic stem cell test, Cell Line, Mice, Aromatase, Life, In vivo, CALUX, Toxicity Tests, Test battery, medicine, Animals, Humans, Zebrafish, ReProGlo, Cells, Cultured, Embryonic Stem Cells, Alternative methods, Reproduction, Reproducibility of Results, Steroid 17-alpha-Hydroxylase, Zebrafish embryotoxicity assay, biology.organism_classification, Rats, Toxicokinetics, Teratogens, Mechanism of action, QS - Quality & Safety RAPID - Risk Analysis for Products in Development, Biological Assay, medicine.symptom, EELS - Earth, Environmental and Life Sciences, Reproductive toxicity, Healthy Living

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af6a530266a1fb50974e9203f78bdad
http://resolver.tudelft.nl/uuid:57b03d9c-0908-400a-a5e9-3fe6868ea773

المؤلفون: Fred C.G.J. Sweep, Majorie B.M. van Duursen, Martin van den Berg, Rosalinde Masereeuw, Anita C A Dankers, Frans G. M. Russel, Maarke J.E. Roelofs, Aldert H. Piersma

المصدر: Toxicological Sciences, 136, 382-91
Toxicological Sciences, 136, 2, pp. 382-91

مصطلحات موضوعية: Male, medicine.medical_specialty, Perfluorooctanesulfonic acid, endocrine system, Abcg2, ATP-binding cassette transporter, Endocrine Disruptors, 010501 environmental sciences, Biology, Toxicology, 01 natural sciences, Mice, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Internal medicine, medicine, Animals, Humans, Testosterone, Blood-Testis Barrier, Cells, Cultured, 030304 developmental biology, 0105 earth and related environmental sciences, P-glycoprotein, 0303 health sciences, Leydig cell, Phthalate, Leydig Cells, 3. Good health, HEK293 Cells, Membrane transport and intracellular motility Renal disorder [NCMLS 5], Endocrinology, medicine.anatomical_structure, chemistry, biology.protein, Hormonal regulation Aetiology, screening and detection [IGMD 6], ATP-Binding Cassette Transporters, Efflux

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dee46c4716b4035bbc80ddf1d883fac
https://doi.org/10.1093/toxsci/kft198

المؤلفون: Rita Cortvrindt, Katja J. Teerds, Bernard Jégou, Jorma Toppari, Timothy W. Gant, Maarke J.E. Roelofs, Stefan Schlatt, Majorie B.M. van Duursen, Emma L. Marczylo, Ans M.M. van Pelt, Janine N. Post, Aldert H. Piersma, Robert E. Chapin, Kim Boekelheide

المساهمون: Environnement viral et chimique & reproduction, Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institute of Biomedicine/Physiology, 'Proefdiervrij' (the Dutch Society for the Replacement of Animal Testing (dsRAT)), the ASAT Foundation., Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

المصدر: Reproductive Toxicology 39 (2013)
Reproductive Toxicology, 39, 63-68
Reproductive Toxicology
Reproductive Toxicology, Elsevier, 2013, 39, pp.63-8. ⟨10.1016/j.reprotox.2013.04.004⟩
Reproductive Toxicology, 2013, 39, pp.63-8. ⟨10.1016/j.reprotox.2013.04.004⟩

مصطلحات موضوعية: Male, Computer science, spermatogonial stem-cells, Cell Culture Techniques, agar-culture-system, Toxicology, Leydig cell, 0302 clinical medicine, Testis, Animal testing, Alternatives to animal testing, 3D cell culture, 0303 health sciences, 030219 obstetrics & reproductive medicine, germ-cells, Sertoli cell, Hazard, 3. Good health, Testicular function, Risk analysis (engineering), Male fertility, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Animal Testing Alternative, Human and Animal Physiology, Testicular toxicity, Risk assessment, invitro differentiation, ta3111, Animal Testing Alternatives, 03 medical and health sciences, Toxicity Tests, Animals, Humans, Spermatogenesis, testicular dysgenesis syndrome, 030304 developmental biology, aromatic-hydrocarbons, Tissue Engineering, business.industry, 3-dimensional culture, ta1184, sertoli-cells, Biotechnology, leydig-cells, Human testis, WIAS, Fysiologie van Mens en Dier, collagen gel matrix, business

وصف الملف: application/pdf; application/octet-stream

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0ef35d99452cfdc9fe4046824aeeee
https://research.wur.nl/en/publications/assuring-safety-without-animal-testing-the-case-for-the-human-tes

المؤلفون: Martin van den Berg, Maarke J.E. Roelofs, Aldert H. Piersma, Majorie B.M. van Duursen

المصدر: Toxicology and applied pharmacology. 268(3)

مصطلحات موضوعية: endocrine system, Swine, Dehydroepiandrosterone, 010501 environmental sciences, Endocrine Disruptors, Toxicology, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Microsomes, Animals, Humans, Aromatase, Cells, Cultured, 030304 developmental biology, 0105 earth and related environmental sciences, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Forskolin, biology, Cytochrome P450, Steroid 17-alpha-Hydroxylase, Radioimmunoassay, Enzyme assay, Enzyme Activation, Enzyme, chemistry, Biochemistry, Microsome, biology.protein, Adrenal Cortex, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994f1524d6ecb2790f3498c38111e25d
https://pubmed.ncbi.nlm.nih.gov/23415678

المؤلفون: Yuya Kobayashi, Benjamin Ma, Deanna L. Kroetz, Maarke J.E. Roelofs, Sook Wah Yee, Ji Ha Choi, Stephanie Hesselson, Ligong Chen, Connie Ha, Hisayo Fukushima, Pui-Yan Kwok, Harunobu Tahara, Kathleen M. Giacomini, Pär Matsson, Richard M. Myers, Nicolas Picard, James E. Shima, Doug Stryke, Susan J. Johns, Elin Sjödin, Annie Poon, Jason M. Gow, Richard A. Castro, Thomas E. Ferrin

المساهمون: Zanger, Ulrich

المصدر: PloS one, vol 4, iss 9
PLoS ONE, Vol 4, Iss 9, p e6942 (2009)
PLoS ONE

مصطلحات موضوعية: Adult, Male, Adolescent, General Science & Technology, Genetics and Genomics/Pharmacogenomics, lcsh:Medicine, ATP-binding cassette transporter, Single-nucleotide polymorphism, Biology, Kidney, 030226 pharmacology & pharmacy, Nucleotide diversity, Promoter Regions, 03 medical and health sciences, 0302 clinical medicine, Gene Frequency, Genetic, Genetics and Genomics/Population Genetics, Genetics, Humans, Polymorphism, Promoter Regions, Genetic, lcsh:Science, Gene, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Polymorphism, Genetic, lcsh:R, Cell Membrane, Kidney metabolism, Genetic Variation, Promoter, Solute carrier family, Pharmacology/Adverse Reactions, Liver, Gene Expression Regulation, Multigene Family, lcsh:Q, ATP-Binding Cassette Transporters, Female, Efflux, Pharmacology/Personalized Medicine, Carrier Proteins, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d723da0a968f5281896b4ddea40a7a
https://escholarship.org/uc/item/1m1186zr