المؤلفون: Prithvi Hemanth, Pallavi Nistala, Vy T. Nguyen, Jose M. Eltit, Richard A. Glennon, Małgorzata Dukat

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: 5-HT2A, 5-HT2B, Ca2+ mobilization assay, agonist, antagonist, QSAR, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1101290/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/f2f80a56888b4989a6bc29f6d4529f18

المؤلفون: Glen E. Kellogg, Yana Cen, Malgorzata Dukat, Keith C. Ellis, Youzhong Guo, Jiong Li, Aaron E. May, Martin K. Safo, Shijun Zhang, Yan Zhang, Umesh R. Desai

المصدر: SLAS Discovery, Vol 28, Iss 6, Pp 255-269 (2023)

مصطلحات موضوعية: Drug discovery ecosystem, Structure-based drug discovery, Quantitative structure-activity relationships, Computational glycomics, Drug Discrimination, Allosteric effectors of hemoglobin, Medicine (General), R5-920, Biotechnology, TP248.13-248.65

Relation: http://www.sciencedirect.com/science/article/pii/S2472555223000175; https://doaj.org/toc/2472-5552; https://doaj.org/article/96b02476711041fea6a676aac62c3785

الاتاحة: https://doi.org/10.1016/j.slasd.2023.02.006
https://doaj.org/article/96b02476711041fea6a676aac62c3785

المؤلفون: Malaika D. Argade, Laura DeCristofano, Nirajan Bhattarai, Marvin K. Schulte, Malgorzata Dukat

المصدر: Results in Chemistry, Vol 4, Iss , Pp 100286- (2022)

مصطلحات موضوعية: Galantamine, Lycoramine, SAR, α7 nAChRs, AChE, Chemistry, QD1-999

Relation: http://www.sciencedirect.com/science/article/pii/S2211715622000054; https://doaj.org/toc/2211-7156; https://doaj.org/article/a8a0f918e2744feeb7aa9fd23db0b4f7

الاتاحة: https://doi.org/10.1016/j.rechem.2022.100286
https://doaj.org/article/a8a0f918e2744feeb7aa9fd23db0b4f7

المؤلفون: Osama I. Alwassil (10885889), Shailesh Khatri (3104355), Marvin K. Schulte (3104364), Sanjay S. Aripaka (10885892), Jens D. Mikkelsen (160806), Małgorzata Dukat (2454808)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Pharmacology, Mental Health, Chemical Sciences not elsewhere classified, aryl 3- position, SAR, compound, N 1, α7 nicotinic ACh receptors, N 1 H, Xenopus laevis oocytes, two-electrode voltage-clamp assay, nature, methyl counterpart 2, novel α7 nAChR antagonist chemotype, α7 Nicotinic Acetylcholine, novel α7 nicotinic ACh, receptor antagonist chemotype, 3- position substituents

Relation: https://figshare.com/articles/journal_contribution/N_sub_1_sub_H-_and_N_sub_1_sub_Substituted_Phenylguanidines_as_7_Nicotinic_Acetylcholine_nACh_Receptor_Antagonists_Structure_Activity_Relationship_Studies/14690942

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00212.s001

المؤلفون: Charles B. Jones, Małgorzata Dukat

المصدر: Medicinal Chemistry Research. 31:643-651

مصطلحات موضوعية: Organic Chemistry, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1405b427e9e5c4b4ac538111f49a425b
https://doi.org/10.1007/s00044-022-02863-5

المؤلفون: Prithvi Hemanth, Pallavi Nistala, Vy T. Nguyen, Jose M. Eltit, Richard A. Glennon, Małgorzata Dukat

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, 5-HT2A, 5-HT2B, Ca2+ mobilization assay, agonist, antagonist, QSAR, psychedelic agents, valvulopathy

Relation: https://figshare.com/articles/dataset/Table1_Binding_and_functional_structure-activity_similarities_of_4-substituted_2_5-dimethoxyphenyl_isopropylamine_analogues_at_5-HT2A_and_5-HT2B_serotonin_receptors_DOCX/21945098

الاتاحة: https://doi.org/10.3389/fphar.2023.1101290.s001
https://figshare.com/articles/dataset/Table1_Binding_and_functional_structure-activity_similarities_of_4-substituted_2_5-dimethoxyphenyl_isopropylamine_analogues_at_5-HT2A_and_5-HT2B_serotonin_receptors_DOCX/21945098

المؤلفون: Osama I, Alwassil, Shailesh, Khatri, Marvin K, Schulte, Sanjay S, Aripaka, Jens D, Mikkelsen, Małgorzata, Dukat

المصدر: ACS chemical neuroscience. 12(12)

مصطلحات موضوعية: Structure-Activity Relationship, Xenopus laevis, alpha7 Nicotinic Acetylcholine Receptor, Oocytes, Animals, Humans, Nicotinic Antagonists, Receptors, Nicotinic, Guanidines, Acetylcholine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::308515b8f117153d158a05d292a49686
https://pubmed.ncbi.nlm.nih.gov/34043311

المؤلفون: Ahmed S, Abdelkhalek, Faik N, Musayev, Kavita A, Iyer, Prithvi, Hemanth, Martin K, Safo, Małgorzata, Dukat

المصدر: J Mol Struct

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::011c444f37ad436d72c39ed6264a4fd7
https://pubmed.ncbi.nlm.nih.gov/32616964

المؤلفون: Jagadeesh B. Rangisetty, Małgorzata Dukat, Cynthia S. Dowd, Katharine Herrick-davis, Ann Dupre

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bitnest.ca/external.php?id%3D%7DbxUgZ%5BC%40X%04uz%7F%03%06%5E.

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.668.3901; http://bitnest.ca/external.php?id%3D%7DbxUgZ%5BC%40X%04uz%7F%03%06%5E

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.668.3901
http://bitnest.ca/external.php?id%3D%7DbxUgZ%5BC%40X%04uz%7F%03%06%5E

المؤلفون: Richard A. Glennon A, Malgorzata Dukat A, Brian Grella A, Seoung-soo Hong A, Luca Costantino A, Milt Teitler B, Carol Smith B, Chris Egan B, Katherine Davis B, Mariena V. Mattson C

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bitnest.ca/external.php?id%3D%7DbxUgY%5CCy%05%07s%7Cb%0C%02V%5DI%0B%5DPw%7Da%11%5Dtq.

مصطلحات موضوعية: www.elsevier.com, locate, drugalcdep

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.687.7984; http://bitnest.ca/external.php?id%3D%7DbxUgY%5CCy%05%07s%7Cb%0C%02V%5DI%0B%5DPw%7Da%11%5Dtq

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.687.7984
http://bitnest.ca/external.php?id%3D%7DbxUgY%5CCy%05%07s%7Cb%0C%02V%5DI%0B%5DPw%7Da%11%5Dtq

المؤلفون: Urjita H, Shah, Supriya A, Gaitonde, José L, Moreno, Richard A, Glennon, Małgorzata, Dukat, Javier, González-Maeso

المصدر: ACS chemical neuroscience. 10(5)

مصطلحات موضوعية: HEK293 Cells, Models, Chemical, Humans, Receptor, Serotonin, 5-HT2A, Ketanserin, Risperidone, Tryptamines, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dfae65f8e588978ea5745b271ae2964c
https://pubmed.ncbi.nlm.nih.gov/30609893

المؤلفون: Richard A. Glennon, Lt Seoung-soo Hong, Malgorzata Dukat, Milt Teitler, Kathy David

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bitnest.ca/external.php?id%3D%7DbxUgZ%5BC%40X%04tz%7B%00TW%5BP.

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.669.4430; http://bitnest.ca/external.php?id%3D%7DbxUgZ%5BC%40X%04tz%7B%00TW%5BP

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.669.4430
http://bitnest.ca/external.php?id%3D%7DbxUgZ%5BC%40X%04tz%7B%00TW%5BP

المؤلفون: Ahmed S, Abdelkhalek, Genevieve S, Alley, Osama I, Alwassil, Shailesh, Khatri, Philip D, Mosier, Heather L, Nyce, Michael M, White, Marvin K, Schulte, Małgorzata, Dukat

المصدر: ACS chemical neuroscience. 10(3)

مصطلحات موضوعية: HEK293 Cells, Dose-Response Relationship, Drug, Xenopus, Animals, Humans, Serotonin 5-HT3 Receptor Antagonists, Female, Receptors, Serotonin, 5-HT3, Guanidines, Methane, Protein Structure, Secondary, Protein Binding, Protein Structure, Tertiary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::49b6c8f5ccb4fbedf7ee2da0baf7a689
https://pubmed.ncbi.nlm.nih.gov/30375852

المؤلفون: Richard A, Glennon, Małgorzata, Dukat

المصدر: Annals of forensic research and analysis. 4(2)

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b21b34910a5a203c77e40f19317b4bd5
https://pubmed.ncbi.nlm.nih.gov/30288398

المؤلفون: Elena, Sguazzini, Hayden R, Schmidt, Kavita A, Iyer, Andrew C, Kruse, Małgorzata, Dukat

المصدر: Bioorganicmedicinal chemistry letters. 27(13)

مصطلحات موضوعية: Models, Molecular, Structure-Activity Relationship, Molecular Structure, Morpholines, Guinea Pigs, Animals, Humans, Receptors, sigma, Ligands, Protein Binding, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::967373666ff5c0770908eb7f1ef02dce
https://pubmed.ncbi.nlm.nih.gov/28495085

المؤلفون: Katie, Alix, Shailesh, Khatri, Philip D, Mosier, Samantha, Casterlow, Dong, Yan, Heather L, Nyce, Michael M, White, Marvin K, Schulte, Małgorzata, Dukat

المصدر: ACS chemical neuroscience. 7(11)

مصطلحات موضوعية: Models, Molecular, Dose-Response Relationship, Drug, Molecular Structure, Xenopus, Serotonin 5-HT3 Receptor Agonists, Guanidines, Membrane Potentials, Mice, HEK293 Cells, Cell Line, Tumor, Mutation, Oocytes, Animals, Humans, Serotonin 5-HT3 Receptor Antagonists, Receptors, Serotonin, 5-HT3, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::28fc769012d16a00c4c918c738b7b36f
https://pubmed.ncbi.nlm.nih.gov/27533595

المؤلفون: Shawquia, Young, Minna, Vainio, Mika, Scheinin, Małgorzata, Dukat

المصدر: Basicclinical pharmacologytoxicology. 107(2)

مصطلحات موضوعية: Male, Tail, Analgesics, Mice, Inbred ICR, Behavior, Animal, Injections, Subcutaneous, Imidazoles, Pain, Yohimbine, Drug Synergism, Isoindoles, Motor Activity, Receptors, Adrenergic, alpha, Guanidines, Clonidine, Mice, Animals, Adrenergic alpha-Antagonists, Pain Measurement

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::94b57d792e809c3d41c309275a57d0a7
https://pubmed.ncbi.nlm.nih.gov/20353485

المؤلفون: Richard A, Glennon, Małgorzata, Dukat

المصدر: Bioorganicmedicinal chemistry letters. 14(8)

مصطلحات موضوعية: Structure-Activity Relationship, Models, Chemical, Molecular Structure, Drug Design, Animals, Hydrogen Bonding, Nicotinic Agonists, Receptors, Nicotinic, Ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::cb372bb3dfce1c32e9d7661a8ea1583d
https://pubmed.ncbi.nlm.nih.gov/15050612

المؤلفون: Małgorzata, Dukat, Richard A, Glennon

المصدر: Cellular and molecular neurobiology. 23(3)

مصطلحات موضوعية: Central Nervous System, Models, Molecular, Neurons, Nicotine, Molecular Structure, Pyridines, Animals, Humans, Receptors, Nicotinic, Bridged Bicyclo Compounds, Heterocyclic, Binding, Competitive, Acetylcholine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1fff20d0e38c9bc607e4871acb8a8c4f
https://pubmed.ncbi.nlm.nih.gov/12825833

المؤلفون: Richard A. Glennon, Małgorzata Dukat

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cb9f27e525e69aa2f90c7da40c60504d
https://doi.org/10.1016/s0165-7208(00)80006-9