يعرض 1 - 20 نتائج من 121 نتيجة بحث عن '"MYC Amplification"', وقت الاستعلام: 0.66s تنقيح النتائج
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    Academic Journal

    المصدر: Nordkild , S B , Ahlborn , L B , Yde , C W , Kugler , J M , Klubien , J , Akdag , D , Willemoe , G L , Nielsen , S D & Pommergaard , H C 2024 , ' Prognostic genomic alterations in patients undergoing liver resection for hepatocellular carcinoma ' , Molecular Biology Reports , vol. 51 , no. 1 , 450 . https://doi.org/10.1007/s11033-024-09396-7

    وصف الملف: application/pdf

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    المصدر: Russian Journal of Pediatric Hematology and Oncology; Том 10, № 3 (2023); 63-69 ; Российский журнал детской гематологии и онкологии (РЖДГиО); Том 10, № 3 (2023); 63-69 ; 2413-5496 ; 2311-1267

    مصطلحات موضوعية: амплификация c-myc, MYC, TERT, ATRX, oct4, c-myc amplification

    وصف الملف: application/pdf

    Relation: https://journal.nodgo.org/jour/article/view/964/848; Shimada H., Chatten J., Newton W.A. Jr, Sachs N., Hamoudi A.B., Chiba T., Marsden H.B., Misugi K. Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas. J Natl Cancer Inst. 1984;73(2):405–16. doi:10.1093/jnci/73.2.405.; Shimada H., Ambros I.M., Dehner L.P., Hata J., Joshi V.V., Roald B., Stram D.O., Gerbing R.B., Lukens J.N., Matthay K.K., Castleberry R.P. The International Neuroblastoma Pathology Classification (the Shimada system). Cancer. 1999;86(2):364–72. doi:10.1002/ (SICI)1097-0142(19990715)86:23.0.CO;2-7.; Ikegaki N., Shimada H.; International Neuroblastoma Pathology Committee. Subgrouping of unfavorable histology neuroblastomas with immunohistochemistry toward precision prognosis and therapy stratification. JCO Precis Oncol. 2019:3:PO.18.00312. doi:10.1200/PO.18.00312.; Ackermann S., Cartolano M., Hero B. A mechanistic classification of clinical phenotypes in neuroblastoma. Science. 2018;362(6419):1165–70. doi:10.1126/science.aat6768.; Seeger R.C., Brodeur G.M., Sather H. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med. 1985;313(18):1111–6. doi:10.1056/nejm198510313131802.; Brodeur G.M., Seeger R.C., Schwab M., Varmus H.E., Bishop J.M. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science. 1984;224(4653):1121–4. doi:10.1126/science.6719137.; Shimada H., Ikegaki N. Genetic and histopathological heterogeneity of neuroblastoma and precision therapeutic approaches for extremely unfavorable histology subgroups. Biomolecules. 2022;12(1):79. doi:10.3390/biom12010079.; Wang L.L., Teshiba R., Ikegaki N., Tang X.X., Naranjo A., London W.B., Hogarty M.D., Gastier-Foster J.M., Look A.T., Park J.R., Maris J.M., Cohn S.L., Seeger R.C., Asgharzadeh S., Shimada H. Augmented expression of Myc and/or MYCN protein defines highly aggressive myc-driven neuroblastoma: A Children’s Oncology Group study. Br J Cancer. 2015;113(1):57–63. doi:10.1038/bjc.2015.188.; Niemas-Teshiba R., Matsuno R., Wang L.L., Tang X.X., Chiu B., Zeki J., Coburn J., Ornell K., Naranjo A., Van Ryn C. MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: A report from the Children’s Oncology Group. Oncotarget. 2018;9:6416–32. doi:10.18632/oncotarget.23740.; Tornoczky T., Kalman E., Kajtar P.G. Large cell neuroblastoma: a distinct phenotype of neuroblastoma with aggressive clinical behavior. Cancer. 2004;100(2):390–7. doi:10.1002/cncr.20005.; Ikegaki N., Shimada H., Fox A.M., Regan P.L., Jacobs J.R., Hicks S.L., Rappaport E.F., Tang X.X. Transient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomas. Proc Natl Acad Sci. (USA) 2013;110:6097–102. doi:10.1073/pnas.1118262110.; Khudyakov J., Bronner-Fraser M. Comprehensive spatiotemporal analysis of early chick neural crest network genes. Dev Dyn. 2009;238(3):716–23. doi:10.1002/dvdy.21881.; Matsuno R., Giff ord A.J., Fang J., Warren M., Lukeis R.E., Trahair T., Sugimoto T., Marachelian A., Asgharzadeh S., Maris J.M. Rare MYCamplified Neuroblastoma With Large Cell Histology. Pediatric Dev Pathol. 2018;21:461–6. doi:10.1177/1093526617749670.; Tornóczky T., Kaszás B., Ottóff y G., Hosnyánszki D., Simon R., Hazard F.K., Shimada H. Large cell neuroblastoma – Phenotypical variant of MYC-driven neuroblastoma: Report of 2 cases with different molecular characteristics. Hum Pathol: Case Reports. 2021;24:200493. doi.org/10.1016/j.ehpc.2021.200493.; Fetahu I.S., Taschner-Mandl S. Neuroblastoma and the epigenome. Cancer Metastasis Rev. 2021;40:173–89. doi:10.1007/s10555-020-09946-y.; Zimmerman M.W., Liu Y., He S., Durbin A.D., Abraham B.J., Easton J., Shao Y., Xu B., Zhu S., Zhang X. MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer Discov. 2018;8:320–35. doi:10.1158/2159-8290.cd-17-0993.; Wei S.J., Nguyen T.H., Yang I.H. MYC transcription activation mediated by OCT4 as a mechanism of resistance to 13-cisRA-mediated differentiation in neuroblastoma. Cell Death Dis. 2020;11:368. doi:10.1038/s41419-020-2563-4.; Duan X.-F., Zhao Q. TERT-mediated and ATRX-mediated Telomere Maintenance and Neuroblastoma. J Pediatr Hematol Oncol. 2018;40(1):1–6. doi:10.1097/MPH.0000000000000840.; Valentijn L.J., Koster J., Zwijnenburg D.A. TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors. Nat Genet. 2015;47:1411–4. doi:10.1038/ng.3438.; Peifer M., Hertwig F., Roels F. Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature. 2015;526:700–4. doi:10.1038/nature14980.; Flynn R.L., Cox K.E., Jeitany M. Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors. Science. 2015;347:273–7. doi:10.1126/science.1257216.; https://journal.nodgo.org/jour/article/view/964

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    المساهمون: Gianno, Francesca, Giovannoni, Isabella, Cafferata, Barbara, Diomedi-Camassei, Francesca, Minasi, Simone, Barresi, Sabina, Buttarelli, Francesca Romana, Alesi, Viola, Cardoni, Antonello, Antonelli, Manila, Puggioni, Chiara, Stefania Colafati, Giovanna, Carai, Andrea, Vinci, Maria, Mastronuzzi, Angela, Miele, Evelina, Alaggio, Rita, Giangaspero, Felice, Rossi, Sabrina

    Relation: info:eu-repo/semantics/altIdentifier/pmid/36534421; info:eu-repo/semantics/altIdentifier/wos/WOS:000997157500004; volume:114; issue:6; firstpage:422; lastpage:435; numberofpages:14; journal:PATHOLOGICA; https://hdl.handle.net/11573/1663588; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85144290593

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    المصدر: Vargas , A C , Grimison , P , Joy , C , Garrone , B , Bonar , F , Ghahan , R M , Davidson , T & Maclean , F M 2022 , ' Chromosome 8 polysomy accounting for MYC over-expression in angiosarcoma arising as somatic-type malignancy in metastatic teratoma. Case report ' , International Journal of Surgical Pathology , vol. 30 , no. 4 , pp. 462-465 . https://doi.org/10.1177/10668969211067762

    مصطلحات موضوعية: angiosarcoma, MYC amplification, polysomy, teratoma

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    Academic Journal

    المؤلفون: Wolf, David, Rotter, Varda

    المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1985 Feb 01. 82(3), 790-794.

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