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المؤلفون: Wen-Fu Tang, Jesse K. Fletcher, Tony Y. Hu, Christopher J. Lyon, Mei-Hua Wan, Qian Hu
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1493-1512 (2021)مصطلحات موضوعية: ALI, acute lung injury, Macrophage, medicine.medical_treatment, Review, DSS, dextran sodium sulphate, Targeted therapy, HUCMSCs, human umbilical cord mesenchymal stem cells, 0302 clinical medicine, General Pharmacology, Toxicology and Pharmaceutics, ICAM-1, intercellular adhesion molecule 1, TNF, tumor necrosis factor, 0303 health sciences, Stem cell, IBD, inflammatory bowel disease, Chemistry, EVs, extracellular vesicles, Extracellular vesicle, Extracellular vesicles, iNOS, inducible nitrogen oxide synthase, Phenotype, MSCs, mesenchymal stromal cells, Cell biology, Inflammatory disease, 030220 oncology & carcinogenesis, Interaction loop, CLP, cecal ligation and puncture, ADSCs, adipose-derived stem cells, AMs, alveolar macrophages, TECs, tubular epithelial cells, Drug carrier, IL-1β, interleukin-1β, PMFA, 5,7,30,40,50-pentamethoxyflavanone, RM1-950, AKI, acute kidney injury, SIRPα, signal regulatory protein α, Sepsis, 03 medical and health sciences, KLF4, krüppel-like factor 4, TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, BMSCs, bone marrow stromal cells, medicine, MHC, major histocompatibility complex, PEG, polyethylene glycol, 030304 developmental biology, HSPA12B, heat shock protein A12B, MVs, microvesicles, Tissue injury, medicine.disease, PPARγ, peroxisome proliferator-activated receptor γ, LPS, lipopolysaccharides, KCs, Kupffer cells, Therapeutics. Pharmacology
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المؤلفون: Xiaohuan Xia, Jialin C. Zheng, Yi Wang
المصدر: Fundamental Research
مصطلحات موضوعية: SARS, Severe acute respiratory syndrome, TAR, Trans-activation response element, viruses, Review, N protein, Nucleocapsid protein, ESCRT, Endosomal sorting complexes required for transport, RLRs, RIG-I-like receptors, ZIKV, Zika virus, Pathogenesis, MVBs, Multivesicular bodies, TBEV, Tick-borne encephalitis virus, Tsg101, Tumor susceptibility gene 101, HCQ, Hydroxychloroquine, CQ, Chloroquine, Receptor, LPS, Lipopolysaccharide, Alix, ALG-2-interacting protein X, COVID-19, Coronavirus disease 2019, biology, PMEL, Premelanosome protein, CNS, Central nervous system, Vesicle, LMP1, Latent membrane protein 1, HRV, Human rhinovirus, EEs, Early endosomes, ZIKA, IAV, Influenza A virus, WNV, West Nile virus, HIV, Human immunodeficiency virus, NDEVs, Neural-derived EVs, EBOV, Ebola virus, Extracellular vesicle, PB, Placental barrier, M protein, Membrane protein, TIM4, T cell immunoglobulin and mucin protein 4 TLRs: Toll-like receptors, RNA virus, SGR, Subgenomic replicon, E protein, Envelope glycoprotein, JEV, Japanese encephalitis virus, Virus, HCV, Hepatitis C virus, nSMase2, Neutral sphingomyelinase-2, pDCs, Plasmacytoid dendritic cells, EBV, Epstein Barr virus, ACE2, Angiotensin-converting enzyme 2, BALF, Bronchoalveolar lavage fluid, HAV, Hepatitis A virus, CV, Coxsackievirus, TMPRSS2, Transmembrane protease serine type 2, EVs, Extracellular vesicles, MHC, Major histocompatibility complex, TNF-α, Tissue necrosis factor-alpha, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, MERS, Middle East respiratory syndrome, MVs, Microvesicles, PV, Poliovirus, RNA, Outbreak, COVID-19, HIV, ARF6, Adenosine diphosphate ribosylation factor 6, IL-1β, Interleukin-1β, S protein, Spike glycoprotein, miRNA, MicroRNA, biology.organism_classification, Virology, Microvesicles, Exosome, PtdSer, phosphatidylserine, HFMD, Hand-foot-and-mouth disease, DENV, Dengue virus, EV71, Enterovirus 71, ILVs, Intraluminal vesicles
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المؤلفون: Amosse, Jérémy, Durcin, Maëva, Malloci, Marine, Vergori, Luisa, Fleury, Audrey, Gagnadoux, Frédéric, Dubois, Séverine, Simard, Gilles, Boursier, Jérôme, Hue, Olivier, Martinez, Maria Carmen, Andriantsitohaina, Ramaroson, Le Lay, Soazig
المساهمون: Stress Oxydant et Pathologies Métaboliques (SOPAM), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)
المصدر: Molecular Metabolism, Vol 18, Iss, Pp 134-142 (2018)
Molecular metabolism
Molecular metabolism, 2018, 18, pp.134-142. ⟨10.1016/j.molmet.2018.10.001⟩
Molecular Metabolismمصطلحات موضوعية: Male, lcsh:Internal medicine, EXOs, exosomes, exosomes, Brief Communication, Mice, Adipokines, Cell-Derived Microparticles, otorhinolaryngologic diseases, Animals, Humans, Obesity, lcsh:RC31-1245, Macrophage Migration-Inhibitory Factors, Cells, Cultured, MIF, Macrophage Migration Inhibitory Factor, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Secretory Pathway, MVs, microvesicles, Macrophages, MIF, EVs, extracellular vesicles, Extracellular vesicles, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Intramolecular Oxidoreductases, RAW 264.7 Cells, Female, microvesicles
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المؤلفون: Mercedes Lopez-Santalla, Juan A. Bueren, Marina I. Garin
المصدر: EBioMedicine, Vol 69, Iss, Pp 103427-(2021)
EBioMedicineمصطلحات موضوعية: Oncology, ID, intradermal, RANTES, regulated upon activation normal T cells expressed and presumably secreted, AS, arthritis score, RA, rheumatoid arthritis, PPAR, peroxisome proliferator-activated receptor, Etanercept, TNF-α, tumour necrosis factor α, Bzb, bortezomib, iLNs, inguinal lymph nodes, CXCR3, chemokine receptor 3-alternative, BMZ, betamethasone, Medicine, CIA, collagen-induced arthritis, PP, peyer's patch, GIP, gastric inhibitory polypeptide, D, days, EVs, extracellular vesicles, Mtx, methotrexate, mAIA, antigen-induced arthritis in mouse, MTC, Masson´s trichrome, 030220 oncology & carcinogenesis, Rheumatoid arthritis, CTLA4, cytotoxic T lymphocyte antigen, iNOS, inducible nitric oxide synthase, KC, keratinocyte chemo-attractant, OCPs, osteoclast precursors, MCP-1, monocyte chemotactic protein 1, PTPN22, protein tyrosine-phosphatase 22, medicine.medical_specialty, rAIA, adjuvant-induced arthritis in rats, MensMSCs, MSCs from menstrual fluid, BM-MSCs, MSCs from bone marrow, MIP-2, macrophage inflammatory protein 2, 03 medical and health sciences, R5-920, IP10, IFN-γ-induced protein 10, IM, intramuscular, NRP-1, neuropilin-1, S, syngeneic, ESR, erythrocyte sedimentation rate, MPs, microparticles, PBMCs, peripheral blood mononuclear cells, AD, adipose tissue, MVs, microvesicles, P, placenta, sCIA, collagen-induced arthritis in sheep, Bregs, regulatory B cells, X, xenogeneic, Improvements in MSC-based therapy, AD-MSCs, MSCs from adipose tissue, 030104 developmental biology, TF, tissue factor, Protocols, Gilz, glucocorticoid-induced leucine zipper, DM, dexamethasone, STAT3, signal transducer and activator of transcription 3, ANA, Anti-nuclear antibodies, SAA, serum amyloid-A, ERDF, European Regional Development Fund, µCT, micro computed tomography imaging, Arthritis, Rheumatoid, T-AOC, total antioxidant capacity, rCIA, collagen-induced arthritis in rats, ISCT, international society for cellular therapy, NF-κB, nuclear factor-kappa B, RORγT, retinoic acid-related orphan receptor, TCR, T cell receptor, OVAIA, ovalbumin-induced arthritis, UC, umbilical cord, CAIA, collagen-antibody induced arthritis, Flk, tyrosine kinase receptor for vascular endothelial growth factor, IDO, indoleamine 2,3-dioxygenase, MMP, matrix metalloproteinase, Tr1, IL-10-expressing T cells, SM, synovial membrane, medicine.anatomical_structure, IAA, indoleacetic acid, MPCs, mesenchymal precursor cells, SNP, sodium nitroprusside, medicine.drug, NA, not available, IL-1RA, IL-1 receptor antagonist, CD, cluster of differentiation, DMARDs, antirheumatic drugs, TBO, toluidine blue O, =, similar to or equal, SM-MSCs, MSCs from synovial membrane, Mesenchymal Stem Cell Transplantation, PB, peripheral blood, G, gingiva tissue, IFA, incomplete Freund´s adjuvant, OVA, ovalbumin, MSCs, mesenchymal stem/ stromal cells, SO, safranin, TRAF, tumour necrosis factor receptor-associated factor, Animals, SP, spleen, ILA, indole-3-lactic acid, mBSA, methylated bovine serum albumin, business.industry, F, female, SF, synovial fluid, Th, T helper cells, TLR, toll-like receptors, BM, bone marrow, Bone marrow, Synovial membrane, MRI, magnetic resonance imaging, WT, wild type, Medicine (General), IHC, immunohistochemical analysis, Review, miR, microRNA, TRACP, tartrate-resistant acid phosphatase, AAV, adeno-associated virus, 0302 clinical medicine, GSH, glutathione, SVF, stromal vascular fraction, H/E, haematoxylin/eosin staining, GITR, glucocorticoid-induced tumour necrosis factor receptor, pLNs, popliteal lymph nodes, FOXP3, General Medicine, IFI, indirect immunofluorescence, Tregs, regulatory T cells, M, male, RF, rheumatoid factor, RNA, ribonucleic acid, TNFR, tumour necrosis factor receptor, <, worse than, IP, intraperitoneal, NuMa, nuclear mitotic apparatus, COMP, cartilage oligomeric matrix protein, GSH-Px, glutathione peroxidase, >, better than, LP, lamina propria, LPS, lipopolysaccharide, IN, intranodal, AT, antithrombin, General Biochemistry, Genetics and Molecular Biology, CM, conditioned medium, Consec., consecutive, RAGE, receptor for advanced glycation products, ETN, etanercept, Humans, dLNs, draining lymph nodes, MDA, malondialdehyde, IFN-γ, interferon gamma, ALP, alkaline phosphatase, HSCs, hematopoietic stem cells, Mesenchymal stem cell, Mesenchymal Stem Cells, medicine.disease, EMA, European medicine agency, IL, interleukin, CFA, Freund's complete adjuvant, DAB, 3,3´-diaminobenzidine, OPG, osteoprotegerin, HMGB-1, high-mobility group box-1, CRP, C reactive protein, Tol-DCs, tolerogenic dendritic cells, 0301 basic medicine, CII, collagen II, SF-MSCs, MSCs from synovial fluid, MPO, myeloperoxidease, A, allogeneic, LDL, low density lipoprotein, APCP, α, β methylene selective A2A adenosine receptor competitive antagonist (CD73 inhibitor), Translational Research, Biomedical, SSEA, severe spontaneous erosive arthritis, mLNs, mesenteric lymph nodes, PGIA, proteoglycan-induced arthritis, Exos, small vesicles/Exosomes, FOXP3, forkhead box P3, RANKL, receptor activator of nuclear factor κB ligand, TGF-β, transforming growth factor β, Stromal vascular fraction, NSAIDs, non-steroidal anti-inflammatory drugs, VEGF, vascular endothelial growth factor, Animal models, AhR, aryl hydrocarbon receptor, DCs, dendritic cells, IV, intravenous, Stromal cell, IA, intra-articular, SIRT1, sirtuin 1, O-MSCs, MSCs from nasal tissue, PA, peri-articular, Tfh, follicular T helper cells, AxLNs, axillar lymph nodes, NK, natural killer cells, T-MSCs, MSCs from tonsil tissue, SOD, superoxide dismutase, Internal medicine, MHC, major histocompatibility complex, GLP-1, glucagon-like peptide 1, G-MSCs, MSCs from gingiva tissue, Mesenchymal stem/stromal cells, PG, proteoglycan, HLA-II, human leukocyte antigen-II, PLGA, poly-lactic-co-glycolic acid, HDL, high density lipoprotein, Ig, immunoglobulin, SC, subcutaneous, P-MSCs, MSCs from placenta tissue, POM-1, sodium polyoxotungstate (CD39 inhibitor), UC-MSCs, MSCs from umbilical cord, business, sIL6R, soluble IL-6 receptor
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المؤلفون: E. Zhou, Qi Tan, Juanjuan Xu, Yang Jin, Pei Ma, Feng Wu, Siwei Song, Sufei Wang, Mengfei Guo, Yumei Li
المصدر: EBioMedicine, Vol 67, Iss, Pp 103365-(2021)
EBioMedicineمصطلحات موضوعية: NAC, neoadjuvant chemotherapy, 0301 basic medicine, PSMA, prostate-specific membrane antigen, Medicine (General), lncRNAs, long noncoding RNAs, Review, HNSCC, head and neck squamous cell carcinoma, TKI, tyrosine kinase inhibitor, ErbB3, receptor tyrosine-protein kinase, AUC, area under the curve, Prostate cancer, PR, partial response, 0302 clinical medicine, APNG, alkylpurine-DNA-N-glycosylase, Neoplasms, MVBs, multivesicular bodies, MISEV2018, minimal information for studies of extracellular vesicles 2018, Medicine, HOTAIR, HOX transcript antisense RNA, Cancer, Melanoma, EVs, extracellular vesicles, General Medicine, Extracellular vesicles, mRNA, messenger RNA, PFS, progression-free survival, sEMPs, small-sized endothelial microparticles, Treatment Outcome, CIRT, carbon ion radiotherapy, 030220 oncology & carcinogenesis, CA19-9, DLBCL, diffuse large B-cell lymphoma, EGFRvIII, a mutant subtype of epidermal growth factor receptor, CEA, carcinoma embryonic antigen, PD, progressive disease, Therapeutic response, LNGFR, low-affinity nerve growth factor receptor, AR-V7, androgen receptor splice variant 7, MDR, multi-drug resistance proteins, General Biochemistry, Genetics and Molecular Biology, OS, overall survival, 03 medical and health sciences, R5-920, Breast cancer, CA19-9, carbohydrate antigen 19-9, NSCLC, non-small cell lung cancer, sEVs, small extracellular vesicles, Biomarkers, Tumor, 5T4, a oncofoetal glycoprotein, Humans, ctDNA, circulating tumour DNA, miRNAs, microRNAs, Liquid biopsy, ADT, androgen deprivation therapy, CRT, chemoradiation therapy, Lung cancer, ICIs, immune checkpoint inhibitors, business.industry, MVs, microvesicles, ALK, anaplastic lymphoma kinase, CTCs, circulating tumour cells, TRPC5, transient receptor potential channel 5, MCSP, melanoma chondroitin sulphate proteoglycan, medicine.disease, Head and neck squamous-cell carcinoma, EGFR, epidermal growth factor receptor, PSA, prostate specific antigen, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, PABP4, poly(A)-binding protein4, GBM, glioblastoma, MGMT, O6-methylguanine DNA methyltransferase, MCAM, melanoma cell adhesion molecule, business, Biomarkers
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المؤلفون: Mehdi Hassanpour, Mohammad Nouri, Jafar Rezaie, Yunes Panahi
المصدر: Infection, Genetics and Evolution
مصطلحات موضوعية: 0301 basic medicine, SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus-2, EBV, Epstein-Barr Virus, STING, Stimulator of INF Genes, DC, Dendritic Cells, EVs, Extracellular Vesicles, MERS, Middle East Respiratory Syndrome, HSV-1, Herpes Simplex Virus 1, PBMNCs, Peripheral Blood Mononuclear Cells, Exosomes, ACE2, Angiotensin-converting Enzyme 2, SARS, Severe Acute Respiratory Syndrome, Molecular Targeted Therapy, ESCRT, Endosomal Sorting Complex Required for Transport, DPP4, Dipeptidyl Peptidase 4, KSHV, Kaposi's Sarcoma-associated Herpesvirus, Extracellular vesicles, ACLF, Acute-on-chronic Liver Failure, PA, Phosphatidic Acid, nSMase, Neutral Sphingomyelinase, Abs, Apoptotic Bodies, Virus Shedding, Cell biology, Infectious Diseases, medicine.anatomical_structure, TIM-1, T-cell Immunoglobulin and Mucin Domain 1, COVID-19, Coronavirus Disease 2019, PBC, Primary Biliary Cirrhosis, ISEV, International Society of Extracellular Vesicles, LIMK, LIM kinase, medicine.symptom, dUTPase, deoxy-uridine triphosphatase, MYLK, Myosin Light Chain Kinase, Signal Transduction, Microbiology (medical), BAL, Bronchoalveolar lavage, MVB, Multivescular Body, ECMO, Extracorporeal Membrane Oxygenation, 030106 microbiology, Inflammation, TMPRSS2, TTSP Family Members Like Transmembrane Protease Serine Type 2, Biology, Antiviral Agents, Microbiology, Exosome, Article, Virus, Alveolar cells, APN, Aminopeptidase N, 03 medical and health sciences, Viral entry, Genetics, medicine, Humans, Secretion, CMV, Cytomegalovirus, Molecular Biology, Ecology, Evolution, Behavior and Systematics, TTSP, Type II Transmembrane Serine Protease, SARS-CoV-2, ILVs, Intraluminal Vesicles, MVs, Microvesicles, Mesenchymal stem cell, COVID-19, MSCs, Mesenchymal stem cells, Virus Internalization, Microvesicles, COVID-19 Drug Treatment, 030104 developmental biology, Viral infection, LMP-1, Latent Membrane Protein 1, COVID-19 virus, ROCK, Rho-associated protein kinases