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    المصدر: Сборник статей

    وصف الملف: application/pdf

    Relation: Актуальные вопросы современной медицинской науки и здравоохранения: сборник статей VIII Международной научно-практической конференции молодых учёных и студентов, Екатеринбург, 19-20 апреля 2023 г.; Ваганова, И. Ю. Опыт терапии распространенного гепатоцеллюлярного рака мультикиназными ингибиторами у пациентов со сниженным функциональным статусом (ECOG 2) / И. Ю. Ваганова, В. В. Петкау. - Текст электронный. // Актуальные вопросы современной медицинской науки и здравоохранения: сборник статей VIII Международной научно-практической конференции молодых учёных и студентов, Екатеринбург, 19-20 апреля 2023 г. – Екатеринбург : УГМУ, 2023. – C. 2133-2136.; http://elib.usma.ru/handle/usma/14336

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    المساهمون: Belli, Valentina, Napolitano, Stefania, De Falco, Vincenzo, Suarato, Gabriella, Perrone, Alessandra, Guerrera, Luigi Pio, Martini, Giulia, Della Corte, Carminia Maria, Martinelli, Erika, Morgillo, Floriana, Turano, Mimmo, Furia, Maria, Argenziano, Giuseppe, Ciardiello, Davide, Ciardiello, Fortunato, Troiani, Teresa

    Relation: volume:8; issue:1; firstpage:1; lastpage:11; numberofpages:11; journal:TRANSLATIONAL MEDICINE COMMUNICATIONS; https://hdl.handle.net/11588/949128; https://transmedcomms.biomedcentral.com/articles/10.1186/s41231-022-00133-5#citeas

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    المصدر: Meditsinskiy sovet = Medical Council; № 11 (2023); 10-17 ; Медицинский Совет; № 11 (2023); 10-17 ; 2658-5790 ; 2079-701X

    وصف الملف: application/pdf

    Relation: https://www.med-sovet.pro/jour/article/view/7663/6797; Бредер В.В., Базин И.С., Балахнин П.В., Виршке Э.Р., Косырев В.Ю., Ледин Е.В. и др. Практические рекомендации по лекарственному лечению больных злокачественными опухолями печени и желчевыводящей системы. Злокачественные опухоли. 2022;12(3s2-1):467–529. https://doi.org/10.18027/2224-5057-2022-12-3s2-467-529.; Каприн А.Д., Старинский В.В., Петрова Г.В. (ред.). Злокачественные новообразования в России в 2017 году (заболеваемость и смертность). М.: МНИОИ; 2018. 250 с. Режим доступа: https://glavonco.ru/upload/pages/cancer-register/statistika_zabol_2017.pdf.; Cheng A.L., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma. J Hepatol. 2022;76(4):862–873. https://doi.org/10.1016/j.jhep.2021.11.030.; Morse M.A., Sun W., Kim R., He A.R., Abada P.B., Mynderse M., Finn R.S. The Role of Angiogenesis in Hepatocellular Carcinoma. Clin Cancer Res. 2019;25(3):912–920. https://doi.org/10.1158/1078-0432.CCR-18-1254.; Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. https://doi.org/10.3322/caac.21492.; Hegde P.S., Wallin J.J., Mancao C. Predictive markers of anti-VEGF and emerging role of angiogenesis inhibitors as immunotherapeutics. Semin Cancer Biol. 2018;52(Pt 2):117–124. https://doi.org/10.1016/j.semcancer.2017.12.002.; Lu L.C., Hsu C., Shao Y.Y., Chao Y., Yen C.J., Shih I.L. et al. Differential OrganSpecific Tumor Response to Immune Checkpoint Inhibitors in Hepatocellular Carcinoma. Liver Cancer. 2019;8(6):480–490. https://doi.org/10.1159/000501275.; Kim H.S., Hong J.Y., Cheon J., Kim I., Kim C.G., Kang B. et al. Different organspecific response to nivolumab to determine the survival outcome of patients with advanced hepatocellular carcinoma (aHCC). J Clin Oncol. 2020;38(Suppl. 15):4584–4584. https://doi.org/10.1200/JCO.2020.38.15_suppl.4584.; Yoong K.F., McNab G., Hübscher S.G., Adams D.H. Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma. J Immunol. 1998;160(8):3978–3988. https://doi.org/10.4049/jimmunol.160.8.3978.; Lee M.S., Ryoo B.Y., Hsu C.H., Numata K., Stein S., Verret W. et al. Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study. Lancet Oncol. 2020;21(6):808–820. https://doi.org/10.1016/S1470-2045(20)30156-X.; Fulgenzi C.A.M., Cheon J., D’Alessio A., Nishida N., Ang C., Marron T.U. et al. Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study. Eur J Cancer. 2022;175:204–213. https://doi.org/10.1016/j.ejca.2022.08.024.; Zhu A.X., Duda D.G., Sahani D.V., Jain R.K. HCC and angiogenesis: possible targets and future directions. Nat Rev Clin Oncol. 2011;8(5):292–301. https://doi.org/10.1038/nrclinonc.2011.30.; Motz G.T., Santoro S.P., Wang L.P., Garrabrant T., Lastra R.R., Hagemann I.S., et al. Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nat Med. 2014;20(6):607–615. https://doi.org/10.1038/nm.3541.; Wallin J.J., Bendell J.C., Funke R., Sznol M., Korski K., Jones S. et al. Atezolizumab in combination with bevacizumab enhances antigenspecific T-cell migration in metastatic renal cell carcinoma. Nat Commun. 2016;7:12624. https://doi.org/10.1038/ncomms12624.; Chen D.S., Hurwitz H. Combinations of Bevacizumab With Cancer Immunotherapy. Cancer J. 2018;24(4):193–204. https://doi.org/10.1097/PPO.0000000000000327.; Herbst R.S., Soria J.C., Kowanetz M., Fine G.D., Hamid O., Gordon M.S. et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014;515(7528):563–567. https://doi.org/10.1038/nature14011.; Finn R.S., Bentley G., Britten C.D., Amado R., Busuttil R.W. Targeting vascular endothelial growth factor with the monoclonal antibody bevacizumab inhibits human hepatocellular carcinoma cells growing in an orthotopic mouse model. Liver Int. 2009;29(2):284–290. https://doi.org/10.1111/j.1478-3231.2008.01762.x.; Boige V., Malka D., Bourredjem A., Dromain C., Baey C., Jacques N. et al. Efficacy, safety, and biomarkers of single-agent bevacizumab therapy in patients with advanced hepatocellular carcinoma. Oncologist. 2012;17(8):1063–1072. https://doi.org/10.1634/theoncologist.2011-0465.; Siegel A.B., Cohen E.I., Ocean A., Lehrer D., Goldenberg A., Knox J.J. et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. J Clin Oncol. 2008;26(18):2992–2928. https://doi.org/10.1200/JCO.2007.15.9947.; Thomas M.B., Garrett-Mayer E., Anis M., Anderton K., Bentz T., Edwards A. et al. A Randomized Phase II Open-Label Multi-Institution Study of the Combination of Bevacizumab and Erlotinib Compared to Sorafenib in the First-Line Treatment of Patients with Advanced Hepatocellular Carcinoma. Oncology. 2018;94(6):329–339. https://doi.org/10.1159/000485384.; Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. N Engl J Med. 2020;382(20):1894–1905. https://doi.org/10.1056/NEJMoa1915745.; Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. IMbrave150: Updated overall survival (OS) data from a global, randomized, open-label phase III study of atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in patients (pts) with unresectable hepatocellular carcinoma (HCC). J Clin Oncol. 2021;39(Suppl. 3):267–267. https://doi.org/10.1200/JCO.2021.39.3_suppl.267.; De Franchis R., Bosch J., Garcia-Tsao G., Reiberger T., Ripoll C. Baveno VII – Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959–974. https://doi.org/10.1016/j.jhep.2021.12.022.; https://www.med-sovet.pro/jour/article/view/7663

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