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1Academic Journal
المؤلفون: Suset Dueñas-Disotuar, Ana Piñar-Gutiérrez, Irene de Lara-Rodríguez, Julia Sastre-Marcos, Emma Anda-Apiñániz, Amelia Oleaga-Alday, JC Galofré, Aida Orois, Victoria Alcázar-Lázaro, Laia Martínez-Guasch, Cecilia Sánchez-Ragnarsson, María Ángeles Gálvez-Moreno, Cristina Familiar-Casado, Tomás Martín-Hernández, Ana R. Romero-Lluch
المصدر: Frontiers in Endocrinology, Vol 15 (2025)
مصطلحات موضوعية: thyroid cancer, bone metastases, survival, skeletal-related events, radioiodine, multikinase inhibitors, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Suset Dueñas-Disotuar, Ana Piñar-Gutiérrez, Irene de Lara-Rodríguez, Julia Sastre-Marcos, Emma Anda-Apiñániz, Amelia Oleaga-Alday, JC Galofré, Aida Orois, Victoria Alcázar-Lázaro, Laia Martínez-Guasch, Cecilia Sánchez-Ragnarsson, María Ángeles Gálvez-Moreno, Cristina Familiar-Casado, Tomás Martín-Hernández, Ana R. Romero-Lluch
المصدر: Frontiers in Endocrinology, Vol 15 (2024)
مصطلحات موضوعية: thyroid cancer, bone metastases, survival, skeletal-related events, radioiodine, multikinase inhibitors, antiresorptive agents, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Alexander Burov, Ekaterina Grigorieva, Timofey Lebedev, Valeria Vedernikova, Vladimir Popenko, Tatiana Astakhova, Olga Leonova, Pavel Spirin, Vladimir Prassolov, Vadim Karpov, Alexey Morozov
المصدر: Frontiers in Molecular Biosciences, Vol 11 (2024)
مصطلحات موضوعية: ubiquitin-proteasome system, non-constitutive proteasomes, multikinase inhibitors, regorafenib, sorafenib, Biology (General), QH301-705.5
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Alessandro Inno, Antonello Veccia, Giorgio Madonia, Alvise Berti, Roberto Bortolotti, Lorena Incorvaia, Antonio Russo, Orazio Caffo, Stefania Gori
المصدر: Frontiers in Cardiovascular Medicine, Vol 11 (2024)
مصطلحات موضوعية: immune checkpoint inhibitors, angiogenesis inhibitors, multikinase inhibitors, cardiovascular toxicity, hypertension, stroke, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Yusra Zarlashat, Shakil Abbas, Abdul Ghaffar
المصدر: Cancers, Vol 16, Iss 11, p 2034 (2024)
مصطلحات موضوعية: hepatocellular carcinoma, hepatocytes, immune system, multikinase inhibitors, immune checkpoint inhibitors, immune microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Relation: https://www.mdpi.com/2072-6694/16/11/2034; https://doaj.org/toc/2072-6694; https://doaj.org/article/a296c869f250406e88f599bb79deed99
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6Academic Journal
المؤلفون: Martínez-Chantar, Maria L, Avila, Matias A, Lu, Shelly C
المصدر: Cancers. 12(10)
مصطلحات موضوعية: early diagnosis, hepatocellular carcinoma, immune checkpoint inhibitors, liquid biopsy, molecular mechanisms, multikinase inhibitors, risk factors, Oncology and Carcinogenesis
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/4kv8w7f7
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7Academic Journal
المؤلفون: Daniela Dias, Inês Damásio, Pedro Marques, Helder Simões, Ricardo Rodrigues, Branca Maria Cavaco, Valeriano Leite
المصدر: European Thyroid Journal, Vol 12, Iss 3, Pp 1-6 (2023)
مصطلحات موضوعية: advanced follicular thyroid carcinoma, gemox (gemcitabine plus oxaliplatin), multikinase inhibitors, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
وصف الملف: electronic resource
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8Academic Journal
المؤلفون: Songporn Oranratnachai, Sasivimol Rattanasiri, Ekaphop Sirachainan, Amarit Tansawet, Nilubol Raunroadroong, Gareth J. McKay, John Attia, Ammarin Thakkinstian
المصدر: Cancer Medicine, Vol 12, Iss 3, Pp 3046-3053 (2023)
مصطلحات موضوعية: FOLFOX, hepatocellular carcinoma, multikinase inhibitors, real‐world data, Sorafenib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-7634
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9Academic Journal
المؤلفون: Neus Basté Rotllan
المصدر: Cancer Medicine, Vol 11, Iss S1, Pp 10-16 (2022)
مصطلحات موضوعية: immunosuppressed patients, multikinase inhibitors, systemic treatment, thyroid carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-7634
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10Academic Journal
المؤلفون: Elena Navarro‐Gonzalez
المصدر: Cancer Medicine, Vol 11, Iss S1, Pp 54-58 (2022)
مصطلحات موضوعية: bisphosphonates, bone metastases, denosumab, lenvatinib, multikinase inhibitors, radioiodine‐refractory thyroid cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-7634
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11Academic Journal
المؤلفون: Marcel Sambo
المصدر: Cancer Medicine, Vol 11, Iss S1, Pp 26-32 (2022)
مصطلحات موضوعية: differentiated thyroid carcinoma, multikinase inhibitors, multiple primary malignant neoplasms, synchronous/metachronous cancers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-7634
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12Academic Journal
المؤلفون: Paula Jimenez‐Fonseca
المصدر: Cancer Medicine, Vol 11, Iss S1, Pp 17-25 (2022)
مصطلحات موضوعية: cardiovascular disease, hypertension, lenvatinib, multikinase inhibitors, sorafenib, thyroid carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-7634
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13Academic Journal
المؤلفون: Urbano Anido Herranz
المصدر: Cancer Medicine, Vol 11, Iss S1, Pp 47-53 (2022)
مصطلحات موضوعية: lenvatinib, multikinase inhibitors, radioiodine‐refractory thyroid cancer, sorafenib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-7634
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14Academic Journal
المؤلفون: Maple Ye Feng, Landon L. Chan, Stephen Lam Chan
المصدر: Current Oncology, Vol 29, Iss 8, Pp 5489-5507 (2022)
مصطلحات موضوعية: advanced hepatocellular carcinoma, systemic therapies, multikinase inhibitors, immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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15Academic Journal
المؤلفون: You-Liang Lai, Kai-Hung Wang, Hsing-Pang Hsieh, Wan-Ching Yen
المصدر: Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-19 (2022)
مصطلحات موضوعية: Hepatocellular carcinoma, Multikinase inhibitors, Aurora kinases, Sorafenib resistance, Medicine
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1423-0127
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16Academic Journal
المؤلفون: Vaganova, I. Y., Petkau, V. V., Ваганова, И. Ю., Петкау, В. В.
المصدر: Сборник статей
مصطلحات موضوعية: HEPATOCELLULAR CANCER, FUNCTIONAL STATUS, MULTIKINASE INHIBITORS, ГЕПАТОЦЕЛЛЮЛЯРНЫЙ РАК, ФУНКЦИОНАЛЬНЫЙ СТАТУС, МУЛЬТИКИНАЗНЫЕ ИНГИБИТОРЫ
وصف الملف: application/pdf
Relation: Актуальные вопросы современной медицинской науки и здравоохранения: сборник статей VIII Международной научно-практической конференции молодых учёных и студентов, Екатеринбург, 19-20 апреля 2023 г.; Ваганова, И. Ю. Опыт терапии распространенного гепатоцеллюлярного рака мультикиназными ингибиторами у пациентов со сниженным функциональным статусом (ECOG 2) / И. Ю. Ваганова, В. В. Петкау. - Текст электронный. // Актуальные вопросы современной медицинской науки и здравоохранения: сборник статей VIII Международной научно-практической конференции молодых учёных и студентов, Екатеринбург, 19-20 апреля 2023 г. – Екатеринбург : УГМУ, 2023. – C. 2133-2136.; http://elib.usma.ru/handle/usma/14336
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17Academic Journal
المؤلفون: Belli, Valentina, Napolitano, Stefania, De Falco, Vincenzo, Suarato, Gabriella, Perrone, Alessandra, Guerrera, Luigi Pio, Martini, Giulia, Della Corte, Carminia Maria, Martinelli, Erika, Morgillo, Floriana, Turano, Mimmo, Furia, Maria, Argenziano, Giuseppe, Ciardiello, Davide, Ciardiello, Fortunato, Troiani, Teresa
المساهمون: Belli, Valentina, Napolitano, Stefania, De Falco, Vincenzo, Suarato, Gabriella, Perrone, Alessandra, Guerrera, Luigi Pio, Martini, Giulia, Della Corte, Carminia Maria, Martinelli, Erika, Morgillo, Floriana, Turano, Mimmo, Furia, Maria, Argenziano, Giuseppe, Ciardiello, Davide, Ciardiello, Fortunato, Troiani, Teresa
مصطلحات موضوعية: Metastatic melanoma, Drug resistance, BRAF and MEK inhibitors, EMT transition, EPH signaling, DDR signaling, multikinase inhibitors, ALW‐II‐41‐27 inhibitor
Relation: volume:8; issue:1; firstpage:1; lastpage:11; numberofpages:11; journal:TRANSLATIONAL MEDICINE COMMUNICATIONS; https://hdl.handle.net/11588/949128; https://transmedcomms.biomedcentral.com/articles/10.1186/s41231-022-00133-5#citeas
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18Academic Journal
المؤلفون: Rui Sousa Martins, Tito Teles Jesus, Luís Cardoso, Paula Soares, João Vinagre
المصدر: Journal of Personalized Medicine; Volume 13; Issue 7; Pages: 1132
مصطلحات موضوعية: MTC, RET, signaling pathways, TKIs, multikinase inhibitors, RET -specific inhibitors
وصف الملف: application/pdf
Relation: https://dx.doi.org/10.3390/jpm13071132
الاتاحة: https://doi.org/10.3390/jpm13071132
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19Academic Journal
المؤلفون: I. A. Dzhanyan, M. N. Khagazheeva, V. V. Breder, D. I. Yudin, I. V. Pogrebnyakov, A. E. Kuzminov, E. Yu. Antonova, N. M. Starostin, И. А. Джанян, М. Н. Хагажеева, В. В. Бредер, Д. И. Юдин, И. В. Погребняков, А. Е. Кузьминов, Е. Ю. Антонова, Н. М. Старостин
المصدر: Meditsinskiy sovet = Medical Council; № 11 (2023); 10-17 ; Медицинский Совет; № 11 (2023); 10-17 ; 2658-5790 ; 2079-701X
مصطلحات موضوعية: симптоматическая терапия, hepatic portal vein thrombosis, multikinase inhibitors, sorafenib, cirrhosis decompensation, first-line therapy, symptomatic therapy, тромбоз воротной вены, мультикиназные ингибиторы, сорафениб, декомпенсация цирроза, первая линия терапии
وصف الملف: application/pdf
Relation: https://www.med-sovet.pro/jour/article/view/7663/6797; Бредер В.В., Базин И.С., Балахнин П.В., Виршке Э.Р., Косырев В.Ю., Ледин Е.В. и др. Практические рекомендации по лекарственному лечению больных злокачественными опухолями печени и желчевыводящей системы. Злокачественные опухоли. 2022;12(3s2-1):467–529. https://doi.org/10.18027/2224-5057-2022-12-3s2-467-529.; Каприн А.Д., Старинский В.В., Петрова Г.В. (ред.). Злокачественные новообразования в России в 2017 году (заболеваемость и смертность). М.: МНИОИ; 2018. 250 с. Режим доступа: https://glavonco.ru/upload/pages/cancer-register/statistika_zabol_2017.pdf.; Cheng A.L., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma. J Hepatol. 2022;76(4):862–873. https://doi.org/10.1016/j.jhep.2021.11.030.; Morse M.A., Sun W., Kim R., He A.R., Abada P.B., Mynderse M., Finn R.S. The Role of Angiogenesis in Hepatocellular Carcinoma. Clin Cancer Res. 2019;25(3):912–920. https://doi.org/10.1158/1078-0432.CCR-18-1254.; Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. https://doi.org/10.3322/caac.21492.; Hegde P.S., Wallin J.J., Mancao C. Predictive markers of anti-VEGF and emerging role of angiogenesis inhibitors as immunotherapeutics. Semin Cancer Biol. 2018;52(Pt 2):117–124. https://doi.org/10.1016/j.semcancer.2017.12.002.; Lu L.C., Hsu C., Shao Y.Y., Chao Y., Yen C.J., Shih I.L. et al. Differential OrganSpecific Tumor Response to Immune Checkpoint Inhibitors in Hepatocellular Carcinoma. Liver Cancer. 2019;8(6):480–490. https://doi.org/10.1159/000501275.; Kim H.S., Hong J.Y., Cheon J., Kim I., Kim C.G., Kang B. et al. Different organspecific response to nivolumab to determine the survival outcome of patients with advanced hepatocellular carcinoma (aHCC). J Clin Oncol. 2020;38(Suppl. 15):4584–4584. https://doi.org/10.1200/JCO.2020.38.15_suppl.4584.; Yoong K.F., McNab G., Hübscher S.G., Adams D.H. Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma. J Immunol. 1998;160(8):3978–3988. https://doi.org/10.4049/jimmunol.160.8.3978.; Lee M.S., Ryoo B.Y., Hsu C.H., Numata K., Stein S., Verret W. et al. Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study. Lancet Oncol. 2020;21(6):808–820. https://doi.org/10.1016/S1470-2045(20)30156-X.; Fulgenzi C.A.M., Cheon J., D’Alessio A., Nishida N., Ang C., Marron T.U. et al. Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study. Eur J Cancer. 2022;175:204–213. https://doi.org/10.1016/j.ejca.2022.08.024.; Zhu A.X., Duda D.G., Sahani D.V., Jain R.K. HCC and angiogenesis: possible targets and future directions. Nat Rev Clin Oncol. 2011;8(5):292–301. https://doi.org/10.1038/nrclinonc.2011.30.; Motz G.T., Santoro S.P., Wang L.P., Garrabrant T., Lastra R.R., Hagemann I.S., et al. Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nat Med. 2014;20(6):607–615. https://doi.org/10.1038/nm.3541.; Wallin J.J., Bendell J.C., Funke R., Sznol M., Korski K., Jones S. et al. Atezolizumab in combination with bevacizumab enhances antigenspecific T-cell migration in metastatic renal cell carcinoma. Nat Commun. 2016;7:12624. https://doi.org/10.1038/ncomms12624.; Chen D.S., Hurwitz H. Combinations of Bevacizumab With Cancer Immunotherapy. Cancer J. 2018;24(4):193–204. https://doi.org/10.1097/PPO.0000000000000327.; Herbst R.S., Soria J.C., Kowanetz M., Fine G.D., Hamid O., Gordon M.S. et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014;515(7528):563–567. https://doi.org/10.1038/nature14011.; Finn R.S., Bentley G., Britten C.D., Amado R., Busuttil R.W. Targeting vascular endothelial growth factor with the monoclonal antibody bevacizumab inhibits human hepatocellular carcinoma cells growing in an orthotopic mouse model. Liver Int. 2009;29(2):284–290. https://doi.org/10.1111/j.1478-3231.2008.01762.x.; Boige V., Malka D., Bourredjem A., Dromain C., Baey C., Jacques N. et al. Efficacy, safety, and biomarkers of single-agent bevacizumab therapy in patients with advanced hepatocellular carcinoma. Oncologist. 2012;17(8):1063–1072. https://doi.org/10.1634/theoncologist.2011-0465.; Siegel A.B., Cohen E.I., Ocean A., Lehrer D., Goldenberg A., Knox J.J. et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. J Clin Oncol. 2008;26(18):2992–2928. https://doi.org/10.1200/JCO.2007.15.9947.; Thomas M.B., Garrett-Mayer E., Anis M., Anderton K., Bentz T., Edwards A. et al. A Randomized Phase II Open-Label Multi-Institution Study of the Combination of Bevacizumab and Erlotinib Compared to Sorafenib in the First-Line Treatment of Patients with Advanced Hepatocellular Carcinoma. Oncology. 2018;94(6):329–339. https://doi.org/10.1159/000485384.; Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. N Engl J Med. 2020;382(20):1894–1905. https://doi.org/10.1056/NEJMoa1915745.; Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. IMbrave150: Updated overall survival (OS) data from a global, randomized, open-label phase III study of atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in patients (pts) with unresectable hepatocellular carcinoma (HCC). J Clin Oncol. 2021;39(Suppl. 3):267–267. https://doi.org/10.1200/JCO.2021.39.3_suppl.267.; De Franchis R., Bosch J., Garcia-Tsao G., Reiberger T., Ripoll C. Baveno VII – Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959–974. https://doi.org/10.1016/j.jhep.2021.12.022.; https://www.med-sovet.pro/jour/article/view/7663
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20Conference
المؤلفون: You-Liang Lai (11520730), Kai-Hung Wang (11987977), Hsing-Pang Hsieh (139595), Wan-Ching Yen (11987980)