المؤلفون: Lhomme, Sébastien, Debroy, Swati, Kamar, Nassim, Legrand-Abravanel, Florence, Metsu, David, Olivier, Marion, Dimeglio, Chloé, Cotler, Scott J, Izopet, Jacques, Dahari, Harel

المساهمون: Laboratoire Virologie CHU Toulouse, Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Loyola University Medical Center (LUMC), University of California (UC), Département de Néphrologie et Transplantation d'organes CHU Toulouse, Pôle Urologie - Néphrologie - Dialyse - Transplantations - Brûlés - Chirurgie plastique - Explorations fonctionnelles et physiologiques CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Innovations Thérapeutiques et Résistances (InTheRes), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), Université de Toulouse (UT), R01-AI078881/NH/NIH HHS/United States R01AI144112/NH/NIH HHS/United States R01-GM121600/NH/NIH HHS/United States

المصدر: ISSN: 1999-4915 ; Viruses ; https://hal.inrae.fr/hal-02625593 ; Viruses, 2019, 11 (7), pp.630. ⟨10.3390/v11070630⟩ ; www.mdpi.com/journal/viruses.

مصطلحات موضوعية: chronic infection, hepatitis E virus, ribavirin, viral kinetics, MESH: Antiviral Agents / therapeutic use, MESH: Female, MESH: Humans, MESH: Immunocompromised Host, MESH: Kinetics, MESH: Male, MESH: Middle Aged, MESH: Organ Transplantation, MESH: Plasma, MESH: RNA, Viral / analysis, MESH: Ribavirin / therapeutic use, MESH: Sustained Virologic Response, MESH: Genotype, MESH: Transplant Recipients, MESH: Treatment Failure, MESH: Virus Replication / drug effects, MESH: Hepatitis E / blood, MESH: Hepatitis E / drug therapy, MESH: Hepatitis E / virology, MESH: Hepatitis E virus / drug effects, MESH: Hepatitis E virus / physiology, MESH: Hepatitis, Chronic / drug therapy, Chronic / virology, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/31323954; PRODINRA: 486140; PUBMED: 31323954; PUBMEDCENTRAL: PMC6669701; WOS: 000478667800038

الاتاحة: https://hal.inrae.fr/hal-02625593
https://hal.inrae.fr/hal-02625593v1/document
https://hal.inrae.fr/hal-02625593v1/file/2019_LHOMME%20S_viruses_1.pdf
https://doi.org/10.3390/v11070630

المؤلفون: Fontaine, Hélène, Alric, Laurent, Labreuche, Julien, Legendre, Benjamin, Louvet, Alexandre, Antoine, Corinne, Legendre, Christophe, Hazzan, Marc, Kamar, Nassim, Dharancy, Sebastien, Pol, Stanislas, Duhamel, Alain, Mathurin, Philippe

المساهمون: Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Physiopathologie du système immunitaire (Inserm U1223), Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Unité de biostatistiques, CRLCC Val d'Aurelle - Paul Lamarque, Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Physiopathologie des Maladies Inflammatoires de l'Intestin, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Service des Maladies de l'Appareil Digestif et de la Nutrition CHRU Lille, Hôpital Claude Huriez Lille, Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Recherche translationnelle sur le diabète - U 1190 (RTD), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Lille Inflammation Research International Center - U 995 (LIRIC), Agence de la biomédecine Saint-Denis la Plaine, Service Néphrologie et transplantation rénale Adultes CHU Necker, Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Néphrologie et Transplantation rénale CHRU-lille, Service de Néphrologie - Immunologie Clinique Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-PRES Université de Toulouse

المصدر: ISSN: 0168-8278.

مصطلحات موضوعية: Kidney transplant recipients, Prognosis, chronic hepatitis B, chronic hepatitis C, MESH: Adult, MESH: Antiviral Agents / therapeutic use, MESH: Hepacivirus / drug effects, MESH: Hepacivirus / physiology, MESH: Hepatitis B virus / drug effects, MESH: Hepatitis B virus / physiology, MESH: Hepatitis B, Chronic / drug therapy, Chronic / virology, MESH: Hepatitis C, MESH: Kidney Transplantation / mortality, MESH: Virus Replication / drug effects, MESH: Case-Control Studies, MESH: Female, MESH: Graft Survival, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

Relation: info:eu-repo/semantics/altIdentifier/pmid/30879789; PUBMED: 30879789; WOS: 000464016500006

الاتاحة: https://ut3-toulouseinp.hal.science/hal-03366042
https://ut3-toulouseinp.hal.science/hal-03366042v1/document
https://ut3-toulouseinp.hal.science/hal-03366042v1/file/S0168827819300200.pdf
https://doi.org/10.1016/j.jhep.2018.12.036

المؤلفون: Bailly, B., Richard, C.-A., Sharma, G., Wang, L., Johansen, L., Cao, J., Pendharkar, V., Sharma, D.-C., Galloux, Marie, Wang, Y., Cui, R., Zou, G., Guillon, P., von Itzstein, M., Eléouët, J.-F., Altmeyer, R.

المساهمون: Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Pasteur Network (Réseau International des Instituts Pasteur), Institute for Glycomics, Griffith University Brisbane, Shandong University, Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)), Institut National de la Recherche Agronomique (INRA), CombinatoRx, Qingdao Municipal Center for Disease Control and Prevention, Partenaires INRAE, Department of Biosystems (BIOSYST), Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), ANR-11-BSV8-0024,BRONCHIOLITEASER,Etude structurale et fonctionnelle du complexe polymérase du virus respiratoire syncytial et recherche d'inhibiteurs(2011)

المصدر: ISSN: 2045-2322.

مصطلحات موضوعية: MESH: Alkaloids / pharmacology, MESH: Animals, MESH: Models, Molecular, MESH: Respiratory Syncytial Virus Infections / drug therapy, MESH: Respiratory Syncytial Virus Infections / virology, MESH: Respiratory Syncytial Virus, Human / drug effects, Human / physiology, MESH: Smoothened Receptor / metabolism, MESH: Transcription, Genetic* / drug effects, MESH: Veratrum / chemistry, MESH: Veratrum Alkaloids / chemistry, MESH: Veratrum Alkaloids / pharmacology, MESH: Cell Line, MESH: Veratrum Alkaloids / therapeutic use, MESH: Viral Proteins / metabolism, MESH: Virus Replication / drug effects, MESH: Virus Replication / genetics, MESH: Virus Replication / physiology, MESH: DNA-Directed RNA Polymerases / metabolism, MESH: Disease Models, Animal, MESH: Drug Resistance, Viral / drug effects, MESH: Female, MESH: Gene Expression Regulation, MESH: Humans, MESH: Mice

Relation: info:eu-repo/semantics/altIdentifier/pmid/27194388; PUBMED: 27194388; PUBMEDCENTRAL: PMC4872165; WOS: 000376372700001

الاتاحة: https://hal.inrae.fr/hal-04671081
https://hal.inrae.fr/hal-04671081v1/document
https://hal.inrae.fr/hal-04671081v1/file/srep25806.pdf
https://doi.org/10.1038/srep25806

المؤلفون: Mounce, Bryan C., Cesaro, Teresa, Moratorio, Gonzalo, Hooikaas, Peter Jan, Yakovleva, Anna, Werneke, Scott W., Smith, Everett Clinton, Poirier, Enzo Z., Simon-Loriere, Etienne, Prot, Matthieu, Tamietti, Carole, Vitry, Sandrine, Volle, Romain, Khou, Cécile, Frenkiel, Marie, Sakuntabhai, Anavaj, Delpeyroux, Francis, Pardigon, Nathalie, Flamand, Marie, Barba-Spaeth, Giovanna, Lafon, Monique, Denison, Mark R., Albert, Matthew L., Vignuzzi, Marco

المساهمون: Populations virales et Pathogenèse - Viral Populations and Pathogenesis, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Immunobiologie des Cellules Dendritiques, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Vanderbilt University Medical Center Nashville, Vanderbilt University Nashville, Cellule Pasteur, Université Paris Diderot - Paris 7 (UPD7)-PRES Sorbonne Paris Cité, Génétique fonctionnelle des Maladies infectieuses - Functional Genetics of Infectious Diseases, Virologie Structurale - Structural Virology, Neuro-Immunologie Virale - Viral Neuro-immunology, Biologie des virus entériques (BVE), Environnement et Risques infectieux - Environment and Infectious Risks (ERI), Institut Pasteur Paris (IP), This work was funded by the Laboratoire d’Excellence via Integrative Biology of Emerging Infectious Diseases (grant no. ANR-10-LABX-62-IBEID to B.C.M. and M.V.), Equipe FRM DEQ20150331759 from the French Fondation pour la Recherche Médicale (to M.V.), Institut Pasteur Defeat Dengue Program (to B.C.M. and M.V.), Erasmus Unipharma-Graduates Program (to T.C.), Amgen Scholars Program at Institut Pasteur (to A.Y.), Het Weerstandfonds (to P.J.H), NIH (grant no.R01AI108197 to M.R.D.), NIH (grant no. U19 AI109680 to M.R.D.), InstitutPasteur Programme Transversal de Recherche (grant no. ZPTR484 to F.D.), Fondation Total (grant no. S-CM15010-05B to F.D.), Roux Howard Cantarini postdoctoral fellowship (to R.V.), Seventh Framework Programme (grant no. 278433-PREDEMICS to N.P.), and Ministry of Defense, Direction Générale de l’Armement (to C.K.)., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 278433,EC:FP7:HEALTH,FP7-HEALTH-2011-two-stage,PREDEMICS(2011)

المصدر: ISSN: 0022-538X.

مصطلحات موضوعية: MESH: Acetyltransferases/metabolism, MESH: Animals, MESH: Ebolavirus/metabolism, MESH: Eflornithine/pharmacology, MESH: Hemorrhagic Fever, Ebola/drug therapy, Ebola/virology, MESH: Humans, MESH: Mice, Inbred C57BL, MESH: Polyamines/metabolism, MESH: RNA Viruses/drug effects, MESH: Spermine/analogs & derivatives, MESH: Antiviral Agents/pharmacology, MESH: Spermine/pharmacology, MESH: Virus Replication/drug effects, MESH: Zika Virus/drug effects, MESH: Zika Virus Infection/drug therapy, MESH: Zika Virus Infection/virology, MESH: Cell Line, MESH: Chikungunya Fever/drug therapy, MESH: Chikungunya Fever/virology, MESH: Chikungunya virus/drug effects, MESH: Chikungunya virus/metabolism, MESH: Disease Outbreaks, MESH: Ebolavirus/drug effects, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

Relation: info:eu-repo/semantics/altIdentifier/pmid/27535047; info:eu-repo/grantAgreement/EC/FP7/278433/EU/Preparedness, Prediction and Prevention of Emerging Zoonotic Viruses with Pandemic Potential using Multidisciplinary Approaches/PREDEMICS; pasteur-01402012; https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012; https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012/document; https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012/file/Mounce%20et%20al_Submitted%20article_v10Apr2015.pdf; PUBMED: 27535047; PUBMEDCENTRAL: PMC5068521

الاتاحة: https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012/file/Mounce%20et%20al_Submitted%20article_v10Apr2015.pdf
https://doi.org/10.1128/JVI.01347-16

المؤلفون: Onorati, Marco, Li, Zhen, Liu, Fuchen, Sousa, André m. M., Nakagawa, Naoki, Li, Mingfeng, Dell’anno, Maria teresa, Gulden, Forrest o., Pochareddy, Sirisha, Tebbenkamp, Andrew t.N., Han, Wenqi, Pletikos, Mihovil, Gao, Tianliuyun, Zhu, Ying, Bichsel, Candace, Varela, Luis, Szigeti-Buck, Klara, Lisgo, Steven, Zhang, Yalan, Testen, Anze, Gao, Xiao-Bing, Mlakar, Jernej, Popovic, Mara, Flamand, Marie, Strittmatter, Stephen m., Kaczmarek, Leonard k., Anton, E.S., Horvath, Tamas l., Lindenbach, Brett d., Sestan, Nenad

المساهمون: Department of Neuroscience, Yale University School of Medicine, Yale School of Medicine New Haven, Connecticut (YSM), Department of Cell Biology and Physiology, University of North Carolina Chapel Hill (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC), Cellular Neuroscience, Neurodegeneration and Repair Program, Departments of Neurology and Neuroscience New Haven, Section of Comparative Medicine New Haven, Institute of Genetic Medicine, Newcastle University Newcastle, Departments of pharmacology and molecular biophysics and biochemistry New Haven, University of Ljubljana, Département de Virologie - Department of Virology, Institut Pasteur Paris (IP), Departments of Internal Medicine, Cellular & Molecular Physiology, Departments of Medicine and Cell Biology & Physiology, Department of Microbial Pathogenesis, Reproductive Neuroscience Unit, Department of Obstetrics and Gynecology and Department of Neurobiology, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism, Kavli Institute for Neuroscience, Yale School of Medicine, Yale School of Medicine New Haven, Connecticut (YSM)-Yale School of Medicine New Haven, Connecticut (YSM), Departments of Psychiatry and Genetics, This work was supported by grants NS076503, MH103339, MH105972, MH106934, MH060929, NS080388, AG034924, AG047270, DC01919, AI120113, and AI089826 from the NIH, SFARI 307705 from the Simons Foundation, and 15-RMA-YALE-31 from Connecticut Innovations’ Regenerative Medicine Research Fund. The Laboratory of Developmental Biology at the University of Washington, Seattle, and Human Developmental Biology Resource were supported by NIH award number HD0008836 and the Joint MRC/Wellcome Trust grant 099175/Z/12/Z, respectively. Additional support was provided by the Kavli Foundation and the Falk Medical Research Trust.

المصدر: ISSN: 2211-1247.

مصطلحات موضوعية: MESH: Brain/embryology, MESH: Brain/pathology, MESH: Neuroglia/ultrastructure, MESH: Neuroglia/virology, MESH: Microcephaly/pathology, MESH: Neurons/drug effects, MESH: Neurons/pathology, MESH: Neurons/virology, MESH: Cell Death/drug effects, MESH: Neuroprotective Agents/pharmacology, MESH: Nucleosides/pharmacology, MESH: Phosphorylation/drug effects, MESH: Neural Stem Cells/ultrastructure, MESH: Protein Kinase Inhibitors/pharmacology, MESH: Protein-Serine-Threonine Kinases/metabolism, MESH: Proto-Oncogene Proteins/metabolism, MESH: Microcephaly/virology, MESH: Receptor Protein-Tyrosine Kinases/metabolism, MESH: Spinal Cord/pathology, MESH: Transcription, Genetic/drug effects, MESH: Virus Replication/drug effects, MESH: Centrosome/drug effects, MESH: Zika Virus/drug effects, MESH: Neural Stem Cells/virology, MESH: Zika Virus/pathogenicity, MESH: Zika Virus/physiology, MESH: Zika Virus/ultrastructure, MESH: Zika Virus Infection/pathology, MESH: Mitochondria/drug effects

Relation: info:eu-repo/semantics/altIdentifier/pmid/27568284; pasteur-01739212; https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212; https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/document; https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/file/1-s2.0-S2211124716311020-main.pdf; PUBMED: 27568284; PUBMEDCENTRAL: PMC5135012

الاتاحة: https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/file/1-s2.0-S2211124716311020-main.pdf
https://doi.org/10.1016/j.celrep.2016.08.038

المؤلفون: Meissner, Eric G., Decalf, Jérémie, Casrouge, Armanda, Masur, Henry, Kottilil, Shyam, Albert, Matthew L., Duffy, Darragh

المساهمون: National Institute of Allergy and Infectious Diseases Bethesda (NIAID-NIH), National Institutes of Health Bethesda, MD, USA (NIH), Critical Care Medicine Department, Division of Infectious Diseases, Department of Microbiology and Immunology, Medical University of South Carolina Charleston (MUSC), Immunobiologie des Cellules Dendritiques, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute of Human Virology (IHV), University of Maryland Baltimore County (UMBC), University of Maryland System-University of Maryland System, Centre d'Immunologie Humaine (CIH), This project was supported by federal funds from the intramural program of the National Institute of Allergy and Infectious Diseases, a PasteurInnov grant (Institut Pasteur), and the European Union FP7 grant PoC-HCV (GA n° 601851). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., European Project: 601851,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-2,POC-HCV(2013)

المصدر: ISSN: 1932-6203.

مصطلحات موضوعية: Blood plasma, Biomarkers, Statistical data, Chemokines, Hepatitis C virus, Viral replication, Enzyme-linked immunoassays, Post translational modifications, MESH: Adult, MESH: Antiviral Agents/therapeutic use, MESH: Fluorenes/therapeutic use, MESH: Hepacivirus/drug effects, MESH: Hepacivirus/physiology, MESH: Hepatitis C, Chronic/blood, Chronic/drug therapy, Chronic/genetics, Chronic/virology, MESH: Humans, MESH: Interferons, MESH: Male, MESH: Benzimidazoles/therapeutic use, MESH: Protein Processing, Post-Translational, MESH: Recurrence, MESH: Ribavirin/therapeutic use, MESH: Sofosbuvir/therapeutic use, MESH: Treatment Outcome, MESH: Viral Load/drug effects, MESH: Virus Replication/drug effects

Relation: info:eu-repo/semantics/altIdentifier/pmid/26181438; info:eu-repo/grantAgreement/EC/FP7/601851/EU/Point-of-care tests to revolutionise the clinical management of patients infected by Hepatitis C virus/POC-HCV; pasteur-01380964; https://pasteur.hal.science/pasteur-01380964; https://pasteur.hal.science/pasteur-01380964/document; https://pasteur.hal.science/pasteur-01380964/file/journal.pone.0133236.PDF; PUBMED: 26181438; PUBMEDCENTRAL: PMC4504464

الاتاحة: https://pasteur.hal.science/pasteur-01380964
https://pasteur.hal.science/pasteur-01380964/document
https://pasteur.hal.science/pasteur-01380964/file/journal.pone.0133236.PDF
https://doi.org/10.1371/journal.pone.0133236

المؤلفون: Camille Hallez, Cristina M. Dorobantu, Mohamed S Bouzidi, Valérie Thiers, Vincent Lucansky, Jean-Pierre Vartanian, Xiongxiong Li, Simon Wain-Hobson, Raphael Gaudin, Rodolphe Suspène

المساهمون: Rétrovirologie moléculaire - Molecular Retrovirology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Collège Doctoral, Sorbonne Université (SU), China National Biotec Group (CNBG), Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Viroclinics Biosciences B. V. [Rotterdam, Netherlands], Biomedical Center Martin [Slovaquie], Jessenius Medical Faculty [Commenius University, Slovaquie] (JFMED), Commenius University in Bratislava - Univerzita Komenského-Commenius University in Bratislava - Univerzita Komenského, Institut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Institut Pasteur and Centre National de la Recherche Scientifique. C.H. and M.S.B. were supported by the Allocation de Recherche du Ministère de la Recherche and Ligue contre le Cancer, respectively. X.L. was supported by a stipend from the Lanzhou Institute of Biological Products Co., Ltd, subsidiary company of China National Biotec Group Company Limited and by a stipend from the Pasteur-Paris University International PhD program. V.L. was supported by the Fondation pour la Recherche Medicale (project no. ING20160435328). C.D. was supported by an EMBO Long Term Fellowship (EMBO ALTF 1428–2016). The study of patients was sponsored by the French National Agency for research on AIDS and hepatitis (ANRS). This work has been published within the framework of IdEx Université de Strasbourg and has received funding from the French State via the French National Research Agency (ANR) as part of the program ‘Investissements d’avenir’ to R.G. This work was supported by an ATIP-AVENIR starting grant to R.G., We would like to thank S. Urban for providing HepG2-NTCP cells, P. Pineau and A. Marchio for the cirrhotic liver samples, M.-L. Michel and S. Pol for serum samples, C. Neuveut, P. Moreau, P. Maillard and B. Quioc for HBV infection, Y. Jacob for the HIF-1α and HIF-1β plasmids, J. Krijnse-Locker and C. Schmitt for electron microscopy immunolabelling and V. Caval, N. Frampton and J. McKeating for helpful discussions., Rétrovirologie moléculaire, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Collège doctoral [Sorbonne universités], Vartanian, Jean-Pierre, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

المصدر: Nature Microbiology
Nature Microbiology, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩
Nature Microbiology, Nature Publishing Group, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩

مصطلحات موضوعية: Liver Cirrhosis, viruses, [SDV]Life Sciences [q-bio], MESH: Virus Replication*/drug effects, Gene Expression, medicine.disease_cause, Virus Replication, Applied Microbiology and Biotechnology, chemistry.chemical_compound, Hypoxia, ComputingMilieux_MISCELLANEOUS, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, 0303 health sciences, MESH: Liver Cirrhosis/enzymology, Cytidine, Transfection, Cobalt, Hepatitis B, MESH: Cobalt/pharmacology, MESH: Deoxyribonuclease I/metabolism, Hepatitis B Core Antigens, 3. Good health, [SDV] Life Sciences [q-bio], Capsid, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Hypoxia-Inducible Factor 1, MESH: Deoxyribonuclease I/genetics, Microbiology (medical), Hepatitis B virus, MESH: Mutation, MESH: Gene Expression, MESH: Hepatitis B/enzymology, MESH: Hypoxia-Inducible Factor 1/metabolism, Immunology, Biology, Microbiology, Gene Expression Regulation, Enzymologic, Cell Line, 03 medical and health sciences, Genetics, medicine, Deoxyribonuclease I, Humans, MESH: Gene Expression Regulation, Enzymologic/drug effects, 030304 developmental biology, MESH: Hypoxia*/chemically induced, MESH: Humans, 030306 microbiology, Virion, MESH: Virion/metabolism, MESH: Hepatitis B Core Antigens/metabolism, Cell Biology, medicine.disease, Molecular biology, In vitro, MESH: Cell Line, MESH: DNA, Viral/metabolism, chemistry, DNA, Viral, Mutation, DNA, MESH: Hepatitis B virus/physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5b9df1192a8473ace5d62d1f522f99
https://hal-pasteur.archives-ouvertes.fr/pasteur-02424852

المؤلفون: Matthew L. Albert, Yoann Barthe, Armanda Casrouge, Arnaud Fontanet, Stanislas Pol, Sylvie Lagaye, Hélène Fontaine, Vincent Mallet, Philippe Sultanik, Christophe Hézode, Estelle Mottez, Laurent Abel, Etienne Gayat, Céline Dorival, Fabrice Carrat, Jean-Pierre Bronowicki, Ioannis Theodorou

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département d'hépatologie, Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Epidémiologie, systèmes d'information, modélisation, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Departement d'Hépatho-Gastro-Enterologie [Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre Hospitalier Universitaire Henri Mondor, Centre d'Immunologie Humaine (CIH), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Service de santé publique [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Immunité et Infection, Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR113-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratory of Human Genetics of Infectious Diseases, Rockefeller University [New York]-Rockefeller Branch, Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of anesthesiology and critical care medicine, Hôpitaux Universitaire Saint-Louis, Lariboisière, Fernand-Widal, Département Infection et Epidémiologie - Department of Infection and Epidemiology, Institut Pasteur [Paris], The CUPIC Cohort study was sponsored and funded by The National Agency for research on Aids and Viral Hepatitis (ANRS), with support by the French Association for the Study of the Liver(AFEF). The authors also wish to acknowledge the Center for Human Immunology for its support of the research project., Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Pasteur [Paris] (IP), CHU Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Centre Hospitalier Universitaire Henri Mondor, Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Saint-Antoine [APHP], Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR113-Université Pierre et Marie Curie - Paris 6 (UPMC), Rockefeller Branch-rockefeller university, Institut Cochin ( UM3 (UMR 8104 / U1016) ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Assistance publique - Hôpitaux de Paris (AP-HP)-Centre Hospitalier Universitaire Henri Mondor, Centre d'Immunologie Humaine ( CIH ), Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Saint-Antoine [APHP], Institut National de la Santé et de la Recherche Médicale ( INSERM ) -IFR113-Université Pierre et Marie Curie - Paris 6 ( UPMC ), Imagine - Institut des maladies génétiques ( IMAGINE - U1163 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris Descartes - Paris 5 ( UPD5 ), Biomarqueurs CArdioNeuroVASCulaires ( BioCANVAS ), Université Paris Diderot - Paris 7 ( UPD7 ) -Université Paris 13 ( UP13 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Département Infection et Epidémiologie

المصدر: Liver International
Liver International, Wiley-Blackwell, 2015, 35 (7), pp.1833-1844. ⟨10.1111/liv.12759⟩
Liver International, 2015, 35 (7), pp.1833-1844. ⟨10.1111/liv.12759⟩
Liver International, Wiley-Blackwell, 2015, 35 (7), pp.1833-1844. 〈10.1111/liv.12759〉

مصطلحات موضوعية: Male, MESH : Aged, MESH : Prospective Studies, MESH : Viral Load, MESH : Hepatitis C, Chronic/blood, Hepacivirus, MESH : Virus Replication/drug effects, Polyethylene Glycols, MESH: Molecular Targeted Therapy, [ SDV.IMM ] Life Sciences [q-bio]/Immunology, Molecular Targeted Therapy, Prospective Studies, MESH: Ribavirin/therapeutic use, MESH : Proline/analogs & derivatives, MESH: Treatment Outcome, MESH : Hepacivirus/drug effects, MESH: Viral Nonstructural Proteins/metabolism, MESH: Middle Aged, MESH: RNA, Viral/blood, virus diseases, MESH : beta 2-Glycoprotein I/blood, Blood proteins, 3. Good health, beta 2-Glycoprotein I, Area Under Curve, MESH: Hepacivirus/genetics, Drug Therapy, Combination, Oligopeptides, Apolipoprotein H, MESH : Biomarkers/blood, MESH: Hepatitis C, Chronic/drug therapy, Proline, MESH: Hepatitis C, Chronic/blood, virological response, MESH: Proline/analogs & derivatives, MESH : Antiviral Agents/therapeutic use, Antiviral Agents, MESH : Proline/therapeutic use, Boceprevir, MESH : Recombinant Proteins/therapeutic use, Humans, chronic hepatitis C, MESH : Middle Aged, Protease Inhibitors, MESH: Interferon-alpha/therapeutic use, MESH : Predictive Value of Tests, Aged, MESH: Polyethylene Glycols/therapeutic use, MESH : Hepacivirus/genetics, MESH: Humans, Surrogate endpoint, MESH : Humans, MESH: beta 2-Glycoprotein I/blood, MESH: ROC Curve, digestive system diseases, chemistry, MESH: Protease Inhibitors/therapeutic use, Immunology, MESH: Female, Biomarkers, Time Factors, MESH : Viral Nonstructural Proteins/antagonists & inhibitors, MESH : Hepatitis C, Chronic/diagnosis, MESH : Protease Inhibitors/therapeutic use, Viral Nonstructural Proteins, Virus Replication, MESH : Polyethylene Glycols/therapeutic use, HCV protease inhibitor, Telaprevir, MESH: Virus Replication/drug effects, MESH: Proline/therapeutic use, chemistry.chemical_compound, apolipoprotein H, MESH: Hepacivirus/drug effects, MESH : RNA, Viral/blood, MESH : Female, MESH: Hepatitis C, Chronic/diagnosis, MESH : Viral Nonstructural Proteins/metabolism, MESH: Aged, Middle Aged, Viral Load, MESH: Hepacivirus/growth & development, Recombinant Proteins, MESH: Predictive Value of Tests, MESH : Hepacivirus/enzymology, Treatment Outcome, RNA, Viral, biomarker, [SDV.IMM]Life Sciences [q-bio]/Immunology, Biomarker (medicine), Female, France, MESH: Viral Load, MESH : Oligopeptides/therapeutic use, MESH : Time Factors, medicine.drug, MESH : Hepatitis C, Chronic/drug therapy, MESH : Molecular Targeted Therapy, MESH: Biomarkers/blood, MESH: Hepacivirus/enzymology, MESH : Male, MESH : Ribavirin/therapeutic use, MESH : Interferon-alpha/therapeutic use, MESH : Treatment Outcome, Biology, Predictive Value of Tests, MESH: Recombinant Proteins/therapeutic use, Ribavirin, medicine, MESH : France, NS3, MESH: Viral Nonstructural Proteins/antagonists & inhibitors, Hepatology, MESH : Drug Therapy, Combination, MESH: Time Factors, Interferon-alpha, Hepatitis C, Chronic, MESH : Hepacivirus/growth & development, MESH: Male, MESH: Prospective Studies, MESH: France, MESH: Drug Therapy, Combination, ROC Curve, MESH: Antiviral Agents/therapeutic use, MESH: Oligopeptides/therapeutic use, MESH: Area Under Curve, MESH : Area Under Curve, MESH : ROC Curve

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90633f842d8de6ea3f7f4df0ad3c882d
https://doi.org/10.1111/liv.12759

المؤلفون: Hallez, Camille, Li, Xiongxiong, Suspene, Rodolphe, Thiers, Valérie, Bouzidi, Mohamed, M Dorobantu, Cristina, Lucansky, Vincent, Wain-Hobson, Simon, Gaudin, Raphael, Vartanian, Jean Pierre

المساهمون: Rétrovirologie moléculaire - Molecular Retrovirology, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Collège Doctoral, Sorbonne Université (SU), China National Biotec Group (CNBG), Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Viroclinics Biosciences B. V. Rotterdam, Netherlands, Biomedical Center Martin Slovaquie, Jessenius Medical Faculty Commenius University, Slovaquie (JFMED), Commenius University in Bratislava - Univerzita Komenského-Commenius University in Bratislava - Univerzita Komenského, Institut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Institut Pasteur and Centre National de la Recherche Scientifique. C.H. and M.S.B. were supported by the Allocation de Recherche du Ministère de la Recherche and Ligue contre le Cancer, respectively. X.L. was supported by a stipend from the Lanzhou Institute of Biological Products Co., Ltd, subsidiary company of China National Biotec Group Company Limited and by a stipend from the Pasteur-Paris University International PhD program. V.L. was supported by the Fondation pour la Recherche Medicale (project no. ING20160435328). C.D. was supported by an EMBO Long Term Fellowship (EMBO ALTF 1428–2016). The study of patients was sponsored by the French National Agency for research on AIDS and hepatitis (ANRS). This work has been published within the framework of IdEx Université de Strasbourg and has received funding from the French State via the French National Research Agency (ANR) as part of the program ‘Investissements d’avenir’ to R.G. This work was supported by an ATIP-AVENIR starting grant to R.G., We would like to thank S. Urban for providing HepG2-NTCP cells, P. Pineau and A. Marchio for the cirrhotic liver samples, M.-L. Michel and S. Pol for serum samples, C. Neuveut, P. Moreau, P. Maillard and B. Quioc for HBV infection, Y. Jacob for the HIF-1α and HIF-1β plasmids, J. Krijnse-Locker and C. Schmitt for electron microscopy immunolabelling and V. Caval, N. Frampton and J. McKeating for helpful discussions.

المصدر: ISSN: 2058-5276.

مصطلحات موضوعية: MESH: Cell Line, MESH: Cobalt/pharmacology, MESH: Humans, MESH: Hypoxia*/chemically induced, MESH: Hypoxia-Inducible Factor 1/metabolism, MESH: Liver Cirrhosis/enzymology, MESH: Mutation, MESH: Virion/metabolism, MESH: Virus Replication*/drug effects, MESH: DNA, Viral/metabolism, MESH: Deoxyribonuclease I/genetics, MESH: Deoxyribonuclease I/metabolism, MESH: Gene Expression, MESH: Gene Expression Regulation, Enzymologic/drug effects, MESH: Hepatitis B/enzymology, MESH: Hepatitis B Core Antigens/metabolism, MESH: Hepatitis B virus/physiology, [SDV]Life Sciences [q-bio], [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

Relation: info:eu-repo/semantics/altIdentifier/pmid/30936483; pasteur-02424852; https://pasteur.hal.science/pasteur-02424852; PUBMED: 30936483

الاتاحة: https://pasteur.hal.science/pasteur-02424852
https://doi.org/10.1038/s41564-019-0405-x

المؤلفون: Matthew L. Albert, Marie-Pascale Frenkiel, Anavaj Sakuntabhai, Carole Tamietti, Anna Yakovleva, Marco Vignuzzi, Francis Delpeyroux, Bryan C. Mounce, Sandrine Vitry, Scott W. Werneke, Etienne Simon-Loriere, Cécile Khou, Everett Clinton Smith, Mark R. Denison, Nathalie Pardigon, Marie Flamand, Peter Jan Hooikaas, Enzo Z. Poirier, Teresa Cesaro, Gonzalo Moratorio, Matthieu Prot, Monique Lafon, Romain Volle, Giovanna Barba-Spaeth

المساهمون: Populations virales et Pathogenèse - Viral Populations and Pathogenesis, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Vanderbilt University Medical Center [Nashville], Vanderbilt University [Nashville], Cellule Pasteur, Université Paris Diderot - Paris 7 (UPD7)-PRES Sorbonne Paris Cité, Génétique fonctionnelle des Maladies infectieuses - Functional Genetics of Infectious Diseases, Virologie Structurale - Structural Virology, Neuro-Immunologie Virale - Viral Neuro-immunology, Biologie des virus entériques (BVE), Environnement et Risques infectieux - Environment and Infectious Risks (ERI), Institut Pasteur [Paris] (IP), This work was funded by the Laboratoire d’Excellence via Integrative Biology of Emerging Infectious Diseases (grant no. ANR-10-LABX-62-IBEID to B.C.M. and M.V.), Equipe FRM DEQ20150331759 from the French Fondation pour la Recherche Médicale (to M.V.), Institut Pasteur Defeat Dengue Program (to B.C.M. and M.V.), Erasmus Unipharma-Graduates Program (to T.C.), Amgen Scholars Program at Institut Pasteur (to A.Y.), Het Weerstandfonds (to P.J.H), NIH (grant no.R01AI108197 to M.R.D.), NIH (grant no. U19 AI109680 to M.R.D.), InstitutPasteur Programme Transversal de Recherche (grant no. ZPTR484 to F.D.), Fondation Total (grant no. S-CM15010-05B to F.D.), Roux Howard Cantarini postdoctoral fellowship (to R.V.), Seventh Framework Programme (grant no. 278433-PREDEMICS to N.P.), and Ministry of Defense, Direction Générale de l’Armement (to C.K.)., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 278433,EC:FP7:HEALTH,FP7-HEALTH-2011-two-stage,PREDEMICS(2011), Vougny, Marie-Christine, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Preparedness, Prediction and Prevention of Emerging Zoonotic Viruses with Pandemic Potential using Multidisciplinary Approaches - PREDEMICS - - EC:FP7:HEALTH2011-11-01 - 2016-10-31 - 278433 - VALID, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris]

المصدر: Journal of Virology
Journal of Virology, 2016, 90 (21), pp.9683-9692. ⟨10.1128/JVI.01347-16⟩
Journal of Virology, American Society for Microbiology, 2016, 90 (21), pp.9683-9692. ⟨10.1128/JVI.01347-16⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Hemorrhagic Fever, Ebola/virology, viruses, Spermine, medicine.disease_cause, Virus Replication, Disease Outbreaks, chemistry.chemical_compound, Mice, Polyamines, Diethylnorspermine, MESH: Animals, MESH: Disease Outbreaks, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, education.field_of_study, Zika Virus Infection, MESH: Chikungunya virus/metabolism, MESH: Antiviral Agents/pharmacology, MESH: Spermine/pharmacology, Ebolavirus, MESH: Virus Replication/drug effects, 3. Good health, MESH: Chikungunya Fever/virology, MESH: Polyamines/metabolism, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, MESH: Ebolavirus/drug effects, [SDV.IMM]Life Sciences [q-bio]/Immunology, MESH: Zika Virus Infection/virology, Chikungunya virus, Eflornithine, [SDV.IMM] Life Sciences [q-bio]/Immunology, Immunology, Population, MESH: Hemorrhagic Fever, Ebola/drug therapy, MESH: Chikungunya virus/drug effects, Biology, Microbiology, Antiviral Agents, Virus, Cell Line, 03 medical and health sciences, MESH: Acetyltransferases/metabolism, Acetyltransferases, MESH: Mice, Inbred C57BL, Virology, Vaccines and Antiviral Agents, medicine, Animals, Humans, RNA Viruses, MESH: Zika Virus/drug effects, education, MESH: Mice, MESH: Spermine/analogs & derivatives, Ebola virus, MESH: Humans, RNA, Zika Virus, Hemorrhagic Fever, Ebola, MESH: Zika Virus Infection/drug therapy, MESH: Cell Line, Mice, Inbred C57BL, MESH: Eflornithine/pharmacology, 030104 developmental biology, MESH: RNA Viruses/drug effects, chemistry, Viral replication, Insect Science, Chikungunya Fever, MESH: Chikungunya Fever/drug therapy, Polyamine, MESH: Ebolavirus/metabolism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b99549b02c685e1b3e4c5f33cb0ff75
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012

المؤلفون: Tamas L. Horvath, Maria Teresa Dell’Anno, Xiao-Bing Gao, Naoki Nakagawa, Anze Testen, Yalan Zhang, Tianliuyun Gao, Mihovil Pletikos, Candace Bichsel, Nenad Sestan, Mingfeng Li, Sirisha Pochareddy, Brett D. Lindenbach, Leonard K. Kaczmarek, Zhen Li, Wenqi Han, Forrest O. Gulden, Fuchen Liu, André M. M. Sousa, Stephen M. Strittmatter, Andrew T.N. Tebbenkamp, Marco Onorati, Steven Lisgo, Jernej Mlakar, Marie Flamand, Mara Popović, Eva S. Anton, Luis Varela, Klara Szigeti-Buck, Ying Zhu

المساهمون: Department of Neuroscience [New Haven], Yale University School of Medicine-Kavli Institute for Neuroscience [New Haven], Department of Cell Biology and Physiology, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC), Cellular Neuroscience, Neurodegeneration and Repair Program, Departments of Neurology and Neuroscience [New Haven], Yale University School of Medicine, Section of Comparative Medicine [New Haven], Institute of Genetic Medicine, Newcastle University [Newcastle], Departments of pharmacology and molecular biophysics and biochemistry [New Haven], University of Ljubljana, Département de Virologie - Department of Virology, Institut Pasteur [Paris], Departments of Internal Medicine, Cellular & Molecular Physiology, Departments of Medicine and Cell Biology & Physiology, Department of Microbial Pathogenesis, Reproductive Neuroscience Unit, Department of Obstetrics and Gynecology and Department of Neurobiology, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism, Kavli Institute for Neuroscience [New Haven], Departments of Psychiatry and Genetics, This work was supported by grants NS076503, MH103339, MH105972, MH106934, MH060929, NS080388, AG034924, AG047270, DC01919, AI120113, and AI089826 from the NIH, SFARI 307705 from the Simons Foundation, and 15-RMA-YALE-31 from Connecticut Innovations’ Regenerative Medicine Research Fund. The Laboratory of Developmental Biology at the University of Washington, Seattle, and Human Developmental Biology Resource were supported by NIH award number HD0008836 and the Joint MRC/Wellcome Trust grant 099175/Z/12/Z, respectively. Additional support was provided by the Kavli Foundation and the Falk Medical Research Trust., Department of Neuroscience, Yale University School of Medicine, Yale School of Medicine [New Haven, Connecticut] (YSM), Institut Pasteur [Paris] (IP), Kavli Institute for Neuroscience, Yale School of Medicine, Yale School of Medicine [New Haven, Connecticut] (YSM)-Yale School of Medicine [New Haven, Connecticut] (YSM)

المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, Vol 16, Iss 10, Pp 2576-2592 (2016)

مصطلحات موضوعية: Genetics and Molecular Biology (all), Microcephaly, Transcription, Genetic, Neocortex, MESH: Neuroepithelial Cells/ultrastructure, Biochemistry, environment and public health, MESH: Brain/virology, Neural Stem Cells, MESH: Centrosome/drug effects, MESH: Mitochondria/metabolism, lcsh:QH301-705.5, Neurons, MESH: Protein-Serine-Threonine Kinases/metabolism, Zika Virus Infection, Brain, MESH: Neurons/virology, MESH: Neural Stem Cells/virology, MESH: Neural Stem Cells/immunology, Nucleosides, MESH: Zika Virus/physiology, MESH: Virus Replication/drug effects, Neural stem cell, 3. Good health, Cell biology, Neuroepithelial cell, MESH: Brain/pathology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Spinal Cord, MESH: Neocortex/pathology, MESH: Neuroepithelial Cells/immunology, Neuroglia, MESH: Receptor Protein-Tyrosine Kinases/metabolism, Article, General Biochemistry, Genetics and Molecular Biology, MESH: Protein Kinase Inhibitors/pharmacology, 03 medical and health sciences, MESH: Gene Expression Profiling, Fetus, Humans, MESH: Phosphorylation/drug effects, Mitosis, MESH: Neural Stem Cells/ultrastructure, Biochemistry, Genetics and Molecular Biology (all), MESH: Humans, Receptor Protein-Tyrosine Kinases, MESH: Zika Virus/pathogenicity, medicine.disease, Immunity, Innate, MESH: Mitosis/drug effects, 030104 developmental biology, MESH: Neuroprotective Agents/pharmacology, MESH: Mitochondria/drug effects, MESH: Spinal Cord/pathology, MESH: Neuroglia/ultrastructure, 0301 basic medicine, MESH: Fetus/virology, viruses, [SDV]Life Sciences [q-bio], Neuroepithelial Cells, MESH: Zika Virus/ultrastructure, Virus Replication, MESH: Neurons/drug effects, MESH: Neuroepithelial Cells/drug effects, MESH: Zika Virus Infection/pathology, MESH: Neurons/pathology, MESH: Immunity, Innate/drug effects, Phosphorylation, Genetics, Cell Death, MESH: Transcription, Genetic/drug effects, MESH: Neuroglia/virology, MESH: Nucleosides/pharmacology, Mitochondria, Neuroprotective Agents, MESH: Neuroglia/pathology, lipids (amino acids, peptides, and proteins), MESH: Zika Virus Infection/virology, Stem cell, Programmed cell death, MESH: Centrosome/metabolism, MESH: Brain/embryology, Protein Serine-Threonine Kinases, Biology, Proto-Oncogene Proteins, MESH: Microcephaly/pathology, medicine, MESH: Zika Virus/drug effects, Protein Kinase Inhibitors, Centrosome, MESH: Neural Stem Cells/enzymology, Gene Expression Profiling, MESH: Proto-Oncogene Proteins/metabolism, Zika Virus, Axl Receptor Tyrosine Kinase, MESH: Microcephaly/virology, Gene expression profiling, MESH: Cell Death/drug effects, lcsh:Biology (General), MESH: Neuroepithelial Cells/virology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8842a91c108e53c206bfa4ca694b4d28
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212

المؤلفون: Darragh Duffy, Eric G. Meissner, Henry Masur, Shyam Kottilil, Matthew L. Albert, Jérémie Decalf, Armanda Casrouge

المساهمون: National Institute of Allergy and Infectious Diseases [Bethesda] (NIAID-NIH), National Institutes of Health [Bethesda] (NIH), Critical Care Medicine Department, National Institutes of Health - NIH, Division of Infectious Diseases, Department of Microbiology and Immunology, Medical University of South Carolina [Charleston] (MUSC), Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute of Human Virology (IHV), University of Maryland [Baltimore County] (UMBC), University of Maryland System-University of Maryland System, Centre d'Immunologie Humaine (CIH), This project was supported by federal funds from the intramural program of the National Institute of Allergy and Infectious Diseases, a PasteurInnov grant (Institut Pasteur), and the European Union FP7 grant PoC-HCV (GA n° 601851). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., European Project: 601851,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-2,POC-HCV(2013), Vougny, Marie-Christine, Point-of-care tests to revolutionise the clinical management of patients infected by Hepatitis C virus - POC-HCV - - EC:FP7:HEALTH2013-09-01 - 2016-08-31 - 601851 - VALID, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: PLoS ONE
PLoS ONE, 2015, 10 (7), pp.e0133236. ⟨10.1371/journal.pone.0133236⟩
PLoS ONE, Vol 10, Iss 7, p e0133236 (2015)
PLoS ONE, Public Library of Science, 2015, 10 (7), pp.e0133236. ⟨10.1371/journal.pone.0133236⟩

مصطلحات موضوعية: Male, MESH: Hepacivirus/drug effects, Sofosbuvir, MESH: Fluorenes/therapeutic use, Hepacivirus, lcsh:Medicine, MESH: Hepatitis C, Chronic/virology, Blood plasma, medicine.disease_cause, Virus Replication, chemistry.chemical_compound, Recurrence, Viral replication, MESH: Interferons, Enzyme-linked immunoassays, MESH: Ribavirin/therapeutic use, lcsh:Science, MESH: Dipeptidyl Peptidase 4/blood, media_common, MESH: Treatment Outcome, Multidisciplinary, biology, Hepatitis C virus, Convalescence, virus diseases, MESH: Protein Processing, Post-Translational, Viral Load, MESH: Virus Replication/drug effects, 3. Good health, Treatment Outcome, MESH: Dipeptidyl Peptidase 4/genetics, [SDV.IMM]Life Sciences [q-bio]/Immunology, Drug Therapy, Combination, Female, Chemokines, Viral load, medicine.drug, Research Article, Ledipasvir, Adult, MESH: Sofosbuvir/therapeutic use, MESH: Hepatitis C, Chronic/drug therapy, [SDV.IMM] Life Sciences [q-bio]/Immunology, media_common.quotation_subject, Dipeptidyl Peptidase 4, MESH: Chemokine CXCL10/genetics, MESH: Convalescence, Antiviral Agents, MESH: Benzimidazoles/therapeutic use, MESH: Viral Load/drug effects, Ribavirin, MESH: Hepacivirus/physiology, medicine, Humans, Fluorenes, MESH: Humans, business.industry, lcsh:R, Correction, MESH: Adult, Hepatitis C, Chronic, MESH: Chemokine CXCL10/blood, biology.organism_classification, Statistical data, digestive system diseases, MESH: Male, Post translational modifications, MESH: Recurrence, Chemokine CXCL10, Regimen, MESH: Drug Therapy, Combination, chemistry, MESH: Hepatitis C, Chronic/blood, Immunology, MESH: Antiviral Agents/therapeutic use, lcsh:Q, Benzimidazoles, Interferons, business, Protein Processing, Post-Translational, MESH: Female, Biomarkers, MESH: Hepatitis C, Chronic/genetics

وصف الملف: application/force-download

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34288c84d102b5e0fb82496371553986
https://hal-pasteur.archives-ouvertes.fr/pasteur-01380964/file/journal.pone.0133236.PDF

المؤلفون: Vincent Mallet, Christophe Hézode, Rasha Mamdouh, Mona Rafik, Alexandre Soulier, Isabelle Rosa, Amira Mohsen, Mai El-Daly, Lenaig Le-Fouler, Philippe Renard, Jacques Izopet, Philippe Bonnard, Melissa E. Laird, Armanda Casrouge, Arnaud Fontanet, Stanislas Pol, Mostafa K. Mohamed, Darragh Duffy, Jean-Michel Pawlotsky, Matthew L. Albert, Mohamed Abdel-Hamid

المساهمون: Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Community Medicine Department, National Research Center, Faculty of medicine, Université Ain Shams, Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), liver diseases research unit, National Hepatology & Tropical Medicine Research Institute, Minia University, Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CNR for Viral Hepatitis B, C, and D, Hôpital Henri Mondor, Service d'hépato-gastro-entérologie [APHP Henri Mondor], Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Hôpital Henri Mondor-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Department of gastroenterology and hepatology, Hôpital Victor Dupouy, Service des maladies infectieuses et tropicales [CHU Tenon], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire de Virologie, CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Service d'hépatologie médicale [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by ANRS grants 12210, 12199, 12135 (MLA, AF), the European Research Council Young Investigator Award (MLA), and the European FP7 project SPHINX (ID 261365). Chronic HCV patient samples were provided from an Inserm sponsored clinical trial and also from the control arm of the REALIZE trial as run by Tibotec (Trial N° VX-950-TiDP24-C216). HCV/HIV patient samples were provided as part of the ANRS HC 20 ETOC study (NCT00901524)., European Project: 261365,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,SPHINX(2010), Epidémiologie des Maladies Emergentes, Pasteur-Cnam risques infectieux et émergents (PACRI), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Tenon [APHP], CHU Cochin [AP-HP]-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire Virologie [CHU Toulouse], Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)

المصدر: Journal of Hepatology
Journal of Hepatology, Elsevier, 2014, 61 (4), pp.770-776. ⟨10.1016/j.jhep.2014.05.040⟩
Journal of Hepatology; Vol 61
Journal of Hepatology, 2014, 61 (4), pp.770-776. ⟨10.1016/j.jhep.2014.05.040⟩

مصطلحات موضوعية: Male, Very low-density lipoprotein, MESH: Ribavirin/administration & dosage, Apolipoprotein B, MESH: HIV Infections*/complications, IL28B, HIV Infections, Hepacivirus, Virus Replication, medicine.disease_cause, Polyethylene Glycols, chemistry.chemical_compound, MESH: Hepacivirus*/drug effects, Host factor, MESH: Treatment Outcome, MESH: Aged, MESH: Middle Aged, biology, Coinfection, Hepatitis C virus, MESH: Polymorphism, Single Nucleotide, Middle Aged, Viral Load, MESH: Hepatitis C*/complications Hepatitis, MESH: Virus Replication/drug effects, Hepatitis C, 3. Good health, Treatment Outcome, beta 2-Glycoprotein I, MESH: Interferon-alpha/administration & dosage, MESH: beta 2-Glycoprotein I*/blood, MESH: Antiviral Agents/administration & dosage, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, MESH: Viral Load, Apolipoprotein H, Adult, Quantitative trait loci, MESH: C*/drug therapy Hepatitis, MESH: beta 2-Glycoprotein I*/genetic, Single-nucleotide polymorphism, Antiviral Agents, Polymorphism, Single Nucleotide, Ribavirin, MESH: Interleukins/genetics, medicine, Humans, SNP, Aged, MESH: C*/immunology Hepatitis, MESH: HIV Infections*/drug therapy, Hepatology, Interleukins, MESH: C*/physiopathology Humans, Interferon-alpha, MESH: Polyethylene Glycols/administration & dosage, MESH: Adult, Virology, MESH: Male, MESH: HIV Infections*/immunology, MESH: Coinfection, MESH: Hepacivirus*/physiology, Lipid metabolism, Apolipoproteins, chemistry, Immunology, biology.protein, MESH: C*/genetics Hepatitis, Interferons, MESH: Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65e22babc37f616ddcec22f8adee8ac
https://hal-pasteur.archives-ouvertes.fr/pasteur-01384212

المؤلفون: Laird, Melissa E., Mohsen, Amira, Duffy, Darragh, Mamdouh, Rasha, Lefouler, Lenaig, Casrouge, Armanda, El-Daly, Mai, Rafik, Mona, Mohamed, Mohamed, Soulier, Alexandre, Pawlotsky, Jean-Michel, Hézode, Christophe, Rosa, Isabelle, Renard, Philippe, Mohamed, Mostafa K., Bonnard, Philippe, Izopet, Jacques, Mallet, Vincent, Pol, Stanislas, Albert, Matthew L., Fontanet, Arnaud

المساهمون: Immunobiologie des Cellules Dendritiques, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Community Medicine Department, National Research Center, Faculty of medicine, Université Ain Shams, Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur Paris (IP)-Conservatoire National des Arts et Métiers CNAM (CNAM)-Institut Pasteur Paris (IP)-Conservatoire National des Arts et Métiers CNAM (CNAM), liver diseases research unit, National Hepatology & Tropical Medicine Research Institute, Minia University, Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CNR for Viral Hepatitis B, C, and D, Hôpital Henri Mondor, Service d'hépato-gastro-entérologie APHP Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Department of gastroenterology and hepatology, Hôpital Victor Dupouy, CHU Tenon AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire Virologie CHU Toulouse, Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Service d'hépatologie médicale CHU Cochin, Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by ANRS grants 12210, 12199, 12135 (MLA, AF), the European Research Council Young Investigator Award (MLA), and the European FP7 project SPHINX (ID 261365). Chronic HCV patient samples were provided from an Inserm sponsored clinical trial and also from the control arm of the REALIZE trial as run by Tibotec (Trial N° VX-950-TiDP24-C216). HCV/HIV patient samples were provided as part of the ANRS HC 20 ETOC study (NCT00901524)., European Project: 261365,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,SPHINX(2010)

المصدر: ISSN: 0168-8278.

مصطلحات موضوعية: Hepatitis C virus, Quantitative trait loci, Lipid metabolism, Apolipoproteins, IL28B, MESH: Adult, MESH: Aged, MESH: Hepatitis C*/complications Hepatitis, MESH: C*/drug therapy Hepatitis, MESH: C*/genetics Hepatitis, MESH: C*/immunology Hepatitis, MESH: C*/physiopathology Humans, MESH: Interferon-alpha/administration & dosage, MESH: Interleukins/genetics, MESH: Male, MESH: Middle Aged, MESH: Polyethylene Glycols/administration & dosage, MESH: Antiviral Agents/administration & dosage, MESH: Polymorphism, Single Nucleotide, MESH: Ribavirin/administration & dosage, MESH: Treatment Outcome, MESH: Viral Load, MESH: Virus Replication/drug effects, MESH: beta 2-Glycoprotein I*/blood, MESH: beta 2-Glycoprotein I*/genetic, MESH: Coinfection, MESH: Female, MESH: HIV Infections*/complications, MESH: HIV Infections*/drug therapy

Relation: info:eu-repo/semantics/altIdentifier/pmid/24905490; info:eu-repo/grantAgreement/EC/FP7/261365/EU/Spontaneous clearance in Patients acutely infected with HCV - Immune profiling, Novel biomarkers and X-omics approaches/SPHINX; PUBMED: 24905490

الاتاحة: https://pasteur.hal.science/pasteur-01384212
https://doi.org/10.1016/j.jhep.2014.05.040

المؤلفون: Séror, Claire, Melki, Marie-Thérèse, Subra, Frédéric, Raza, Syed Qasim, Bras, Marlène, Saidi, Héla, Nardacci, Roberta, Voisin, Laurent, Paoletti, Audrey, Law, Fredéric, Martins, Isabelle, Amendola, Alessandra, Abdul-Sater, Ali, Ciccosanti, Fabiola, Delelis, Olivier, Niedergang, Florence, Thierry, Sylvain, Saïd-Sadier, Najwane, Lamaze, Christophe, Métivier, Didier, Estaquier, Jérôme, Fimia, Gian Maria, Falasca, Laura, Casetti, Rita, Modjtahedi, Nazanine, Kanellopoulos, Jean, M., Mouscadet, Jean-François, Ojcius, David, M., Piacentini, Mauro, Gougeon, Marie-Lise, Kroemer, Guido, Perfettini, Jean-Luc

المساهمون: Apoptose, cancer et immunité (U848), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité Anti-virale, Biothérapie et Vaccins (IABV), Institut Pasteur Paris (IP), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), National Institute for Infectious Diseases "Lazzaro Spallanzani", University of California Merced (UC Merced), University of California (UC), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Morphogénèse et Signalisation Cellulaires, Institut Curie Paris -Centre National de la Recherche Scientifique (CNRS), Institut de biochimie et biophysique moléculaire et cellulaire (IBBMC), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Infectious Diseases Research Center Québec, Université Laval Québec (ULaval), Istituto Nazionale di Malattie Infettive "Lazzaro Spallanzani" (INMI), Université Paris Diderot - Paris 7 (UPD7), Università degli Studi di Roma Tor Vergata Roma, Italia = University of Rome Tor Vergata Rome, Italy = Université de Rome Tor Vergata Rome, Italie, Apoptose, cancer et immunité (Equipe labellisée Ligue contre le cancer - CRC - Inserm U1138), Institut Gustave Roussy (IGR)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 (UPD5), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), Pôle de biologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Européen Georges Pompidou APHP (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), This work has been supported by a grant from Sidaction (to J.-L. Perfettini), as well as grants from Agence Nationale des Recherches sur le Sida et sur les hépatites virales, La Ligue Nationale contre le Cancer, Sidaction, and the European Commission (RIGHT, ACTIVE P53, ApoSys, ArtForce, to G. Kroemer) and Istituto Superiore di Sanità (no. 40F60, Ricerca Corrente e Finalizzate “Ministerio della Saluté”, COFIN from Ministro dell’Istruzione, dell’Università e della Ricerca and Associazione Italiana per la Ricerca sul Cancro)., We thank the National Institutes of Health AIDS Research and Reference Reagent Program (Bethesda, MD) and Laurie Erb (Bond Life Sciences Center, USA) for reagents, and A. Jalil (Institut National de la Santé et de la Recherche Médicale U753, France) and O. Duc (Institut Gustave Roussy, France) for technical help.

المصدر: ISSN: 0022-1007.

مصطلحات موضوعية: MESH: Adenosine Triphosphate/genetics, MESH: Adenosine Triphosphate/metabolism, MESH: Enzyme Activation/drug effects, MESH: Focal Adhesion Kinase 2/genetics, MESH: Focal Adhesion Kinase 2/metabolism, MESH: HIV Infections/drug therapy, MESH: HIV Infections/genetics, MESH: HIV Infections/metabolism, MESH: HIV-1/physiology, MESH: Humans, MESH: Male, MESH: Mutation, MESH: Adult, MESH: Nerve Tissue Proteins/genetics, MESH: Nerve Tissue Proteins/metabolism, MESH: Receptors, Purinergic P2Y2/genetics, Purinergic P2Y2/metabolism, MESH: Signal Transduction, MESH: Virus Replication/drug effects, MESH: Virus Replication/genetics, MESH: Antiretroviral Therapy, Highly Active/methods, MESH: Cell Membrane/genetics, MESH: Connexins/genetics, MESH: Connexins/metabolism, MESH: Drug Resistance, Viral/drug effects, Viral/genetics, MESH: Enzyme Activation/genetics

Relation: info:eu-repo/semantics/altIdentifier/pmid/21859844; PUBMED: 21859844; PUBMEDCENTRAL: PMC3171090

الاتاحة: https://hal.science/hal-02356570
https://doi.org/10.1084/jem.20101805

المؤلفون: Syed Qasim Raza, Héla Saïdi, Jean Kanellopoulos, Claire Séror, Marie Thérèse Melki, David M. Ojcius, Gian Maria Fimia, Christophe Lamaze, Jean-François Mouscadet, Audrey Paoletti, Isabelle Martins, Rita Casetti, Laurent Voisin, Marlène Bras, Mauro Piacentini, Alessandra Amendola, Guido Kroemer, Frédéric Law, Frédéric Subra, Fabiola Ciccosanti, Florence Niedergang, Marie-Lise Gougeon, Didier Métivier, Olivier Delelis, Najwane Said-Sadier, Ali A. Abdul-Sater, Laura Falasca, Nazanine Modjtahedi, Jérôme Estaquier, Jean-Luc Perfettini, Sylvain Thierry, Roberta Nardacci

المساهمون: Apoptose, cancer et immunité (U848), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité Anti-virale, Biothérapie et Vaccins (IABV), Institut Pasteur [Paris], Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), National Institute for Infectious Diseases 'Lazzaro Spallanzani', University of California [Merced], University of California, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Morphogénèse et Signalisation Cellulaires, Institut Curie [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut de biochimie et biophysique moléculaire et cellulaire (IBBMC), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Infectious Diseases Research Center [Québec], Université Laval [Québec] (ULaval), Istituto Nazionale di Malattie Infettive 'Lazzaro Spallanzani' (INMI), Université Paris Diderot - Paris 7 (UPD7), Università degli Studi di Roma Tor Vergata [Roma], Apoptose, cancer et immunité (Equipe labellisée Ligue contre le cancer - CRC - Inserm U1138), Institut Gustave Roussy (IGR)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 (UPD5), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), Pôle de biologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), This work has been supported by a grant from Sidaction (to J.-L. Perfettini), as well as grants from Agence Nationale des Recherches sur le Sida et sur les hépatites virales, La Ligue Nationale contre le Cancer, Sidaction, and the European Commission (RIGHT, ACTIVE P53, ApoSys, ArtForce, to G. Kroemer) and Istituto Superiore di Sanità (no. 40F60, Ricerca Corrente e Finalizzate 'Ministerio della Saluté', COFIN from Ministro dell’Istruzione, dell’Università e della Ricerca and Associazione Italiana per la Ricerca sul Cancro)., We thank the National Institutes of Health AIDS Research and Reference Reagent Program (Bethesda, MD) and Laurie Erb (Bond Life Sciences Center, USA) for reagents, and A. Jalil (Institut National de la Santé et de la Recherche Médicale U753, France) and O. Duc (Institut Gustave Roussy, France) for technical help., Institut Pasteur [Paris] (IP), University of California [Merced] (UC Merced), University of California (UC), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-École Pratique des Hautes Études (EPHE), Séror, Claire, Melki, Marie Thérèse, Subra, Frédéric, Raza, Syed Qasim, Bras, Marlène, Saïdi, Héla, Nardacci, Roberta, Voisin, Laurent, Paoletti, Audrey, Law, Frédéric, Martins, Isabelle, Amendola, Alessandra, Abdul Sater, Ali A, Ciccosanti, Fabiola, Delelis, Olivier, Niedergang, Florence, Thierry, Sylvain, Said Sadier, Najwane, Lamaze, Christophe, Métivier, Didier, Estaquier, Jérome, Fimia, Gian Maria, Falasca, Laura, Casetti, Rita, Modjtahedi, Nazanine, Kanellopoulos, Jean, Mouscadet, Jean Françoi, Ojcius, David M, Piacentini, Mauro, Gougeon, Marie Lise, Kroemer, Guido, Perfettini, Jean Luc, Institut Curie-Centre National de la Recherche Scientifique (CNRS), Université Laval, École pratique des hautes études (EPHE)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-École pratique des hautes études (EPHE)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), École pratique des hautes études (EPHE)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)

المصدر: Journal of Experimental Medicine; Vol 208
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2011, 208 (9), pp.1823-1834. ⟨10.1084/jem.20101805⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, 2011, 208 (9), pp.1823-1834. ⟨10.1084/jem.20101805⟩

مصطلحات موضوعية: Male, MESH: Signal Transduction, P2Y receptor, Chemokine, MESH: Enzyme Activation/drug effects, [SDV]Life Sciences [q-bio], Drug Resistance, HIV Infections, Virus Replication, Connexins, MESH: Receptors, Purinergic P2Y2/genetics, Receptors, Purinergic P2Y2, chemistry.chemical_compound, Adenosine Triphosphate, 0302 clinical medicine, Antiretroviral Therapy, Highly Active, MESH: Focal Adhesion Kinase 2/metabolism, Receptors, MESH: Connexins/genetics, MESH: HIV Infections/genetics, Immunology and Allergy, HIV Infection, Viral, Receptor, 0303 health sciences, MESH: HIV Infections/drug therapy, Purinergic receptor, virus diseases, MESH: Antiretroviral Therapy, Highly Active/methods, Purinergic signalling, MESH: Virus Replication/drug effects, 3. Good health, Cell biology, MESH: Connexins/metabolism, Adult, Antiretroviral Therapy, Highly Active, Cell Membrane, Enzyme Activation, Focal Adhesion Kinase 2, HIV-1, Humans, Nerve Tissue Proteins, Purinergic P2Y2, Signal Transduction, Mutation, MESH: HIV-1/physiology, MESH: Focal Adhesion Kinase 2/genetics, Signal transduction, Human, MESH: Cell Membrane/genetics, MESH: Virus Replication/genetics, Settore BIO/06, MESH: HIV Infections/metabolism, MESH: Drug Resistance, Viral/drug effects, MESH: Enzyme Activation/genetics, Immunology, Connexin, Biology, MESH: Drug Resistance, Viral/genetics, Article, 03 medical and health sciences, Drug Resistance, Viral, Extracellular, MESH: Adenosine Triphosphate/metabolism, 030304 developmental biology, MESH: Humans, MESH: Receptors, Purinergic P2Y2/metabolism, MESH: Nerve Tissue Proteins/metabolism, MESH: Adult, MESH: Nerve Tissue Proteins/genetics, MESH: Male, MESH: Adenosine Triphosphate/genetics, chemistry, Nerve Tissue Protein, MESH: Mutation, biology.protein, Adenosine triphosphate, 030217 neurology & neurosurgery

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8255f06ecca1664b78c8748ed44621
http://hdl.handle.net/2108/19411