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1Academic Journal
المؤلفون: Canet, Geoffrey, Zussy, Charleine, Hernandez, Célia, Maurice, Tangui, Desrumaux, Catherine, Givalois, Laurent
المساهمون: Mécanismes moléculaires dans les démences neurodégénératives (MMDN), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Laval University Medical center, Université Laval Québec (ULaval), ANR-11-LABX-0021,Lipstic,Lipoprotéines et santé : prévention et traitement des maladies inflammatoires non vasculaires et du cancer(2011)
المصدر: ISSN: 0163-7258.
مصطلحات موضوعية: Acute model, Alzheimer's disease, Amyloid-beta fragment, Pharmacological screening, Preclinical studies, Rodent, MESH: Aged, MESH: Alzheimer Disease / genetics, MESH: Amyloid beta-Peptides / metabolism, MESH: Animals, MESH: Humans, MESH: Hypothalamo-Hypophyseal System, MESH: Oxidative Stress, MESH: Pituitary-Adrenal System / metabolism, MESH: Pituitary-Adrenal System / pathology, MESH: tau Proteins / metabolism, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences
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2Academic Journal
المؤلفون: Huin, Vincent, Deramecourt, Vincent, Caparros-Lefebvre, Dominique, Maurage, Claude-Alain, Duyckaerts, Charles, Kovari, Eniko, Pasquier, Florence, Buée-Scherrer, Valérie, Labreuche, Julien, Behal, Hélène, Buée, Luc, Dhaenens, Claire-Marie, Sablonnière, Bernard
المساهمون: Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 (JPArc), Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille
المصدر: ISSN: 0885-3185.
مصطلحات موضوعية: PSP, tauopathy, DNA methylation, epigenetic, microtubule-associated protein tau, mapt, epigenomic, promoter, Progressive Supranuclear Palsy, MESH: Aged, 80 and over, MESH: Promoter Regions, Genetic, MESH: Supranuclear Palsy, Progressive / metabolism, MESH: Tissue Banks, MESH: tau Proteins / metabolism, MESH: Alzheimer Disease / metabolism, MESH: CpG Islands, MESH: DNA Methylation, MESH: Female, MESH: Frontal Lobe / metabolism, MESH: Humans, MESH: Introns, MESH: Male, MESH: Middle Aged, MESH: Occipital Lobe / metabolism, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]
Relation: info:eu-repo/semantics/altIdentifier/pmid/27709663; hal-03015965; https://hal.science/hal-03015965; https://hal.science/hal-03015965v2/document; https://hal.science/hal-03015965v2/file/Huin.Movement.Disorders.2016.Author%20version.pdf; PUBMED: 27709663
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3Academic Journal
المؤلفون: Schoemaker, Dorothee, Charidimou, Andreas, Zanon Zotin, Maria Clara, Raposo, Nicolas, Johnson, Keith, Sanchez, Justin, Greenberg, Steven, Viswanathan, Anand
المساهمون: Massachusetts General Hospital Boston, Harvard Medical School Boston (HMS), Département Neurologie CHU Toulouse, Pôle Neurosciences CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Toulouse NeuroImaging Center (ToNIC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Brigham and Women's Hospital Boston
المصدر: ISSN: 0028-3878.
مصطلحات موضوعية: MESH: Aged, MESH: Cerebral Amyloid Angiopathy / complications, MESH: Positron-Emission Tomography, MESH: tau Proteins / metabolism, MESH: Cerebral Amyloid Angiopathy / diagnostic imaging, MESH: Cerebral Amyloid Angiopathy / metabolism, MESH: Cross-Sectional Studies, MESH: Female, MESH: Humans, MESH: Male, MESH: Memory Disorders / etiology, MESH: Neuroimaging / methods, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Relation: info:eu-repo/semantics/altIdentifier/pmid/33627498; PUBMED: 33627498; PUBMEDCENTRAL: PMC8166424
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4
المؤلفون: HUIN, Vincent, Deramecourt, Vincent, Caparros-Lefebvre, Dominique, Maurage, Claude-Alain, Duyckaerts, Charles, Kovari, Eniko, Pasquier, Florence, Buée-Scherrer, Valérie, Labreuche, Julien, Behal, Hélène, Buée, Luc, Dhaenens, Claire-Marie, Sablonnière, Bernard
المساهمون: Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U1172 Inserm - U837 (JPArc), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Lille Nord de France (COMUE)-Université de Lille, Centre National de la Recherche Scientifique (CNRS)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Movement Disorders, Vol. 31, No 12 (2016) pp. 1883-1890
Movement Disorders
Movement Disorders, Wiley, 2016, 31 (12), pp.1883-1890. ⟨10.1002/mds.26820⟩مصطلحات موضوعية: Male, MESH: Introns, epigenomic, MESH: Alzheimer Disease / metabolism, ddc:616.89, MESH: Aged, 80 and over, MESH: DNA Methylation, Promoter Regions, Genetic, MESH: CpG Islands, Aged, 80 and over, PSP, MESH: Aged, DNA methylation, MESH: Middle Aged, mapt, Middle Aged, Frontal Lobe, Female, Neurons and Cognition (q-bio.NC), [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Occipital Lobe, Supranuclear Palsy, Progressive, epigenetic, tau Proteins, Tissue Banks, MESH: Tissue Banks, MESH: Frontal Lobe / metabolism, MESH: Occipital Lobe / metabolism, Alzheimer Disease, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], MESH: Promoter Regions, Genetic, Humans, Quantitative Biology - Genomics, Aged, Genomics (q-bio.GN), MESH: Supranuclear Palsy, Progressive / metabolism, promoter, MESH: Humans, Progressive Supranuclear Palsy, tauopathy, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: tau Proteins / metabolism, Introns, MESH: Male, eye diseases, nervous system diseases, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, FOS: Biological sciences, Quantitative Biology - Neurons and Cognition, CpG Islands, microtubule-associated protein tau, MESH: Female, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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5
المؤلفون: Isabelle Landrieu, François-Xavier Cantrelle, Yoann Sottejeau, Guy Lippens, Idir Malki, Jean-Charles Lambert
المساهمون: Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), The NMR facilities were funded by the Nord Region Council, CNRS, Pasteur Institute of Lille, European Community (FEDER), French Research Ministry and Lille University. We acknowledge support from TGE RMN THC (FR-3050, France) and FRABio (Univ. Lille, CNRS, FR 3688). This study was supported by a grant from the LabEx (Laboratory of Excellence), DISTALZ (Development of Innovative Strategies for a Transdisciplinary approach to Alzheimer's disease), by the French government funding agency Agence Nationale de la Recherche ANR-15-CE16-0002 BinAlz and by the Alzheimer's association (BFG-14-318355)., Institut National de la Recherche Agronomique (INRA)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Recherche Agronomique (INRA), CNRS, Université de Lille, Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 [UGSF], Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE], Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
المصدر: FEBS Journal
FEBS Journal, 2017, 284 (19), pp.3218-3229. ⟨10.1111/febs.14185⟩
FEBS Journal, Wiley, 2017, 284 (19), pp.3218-3229. ⟨10.1111/febs.14185⟩مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, alpha-Helical, Alzheimer’s disease, BIN1, nuclearmagnetic resonance spectroscopy, protein–protein interaction, SH3 domain, Tau, MESH: Sequence Homology, Amino Acid, MESH: Adaptor Proteins, Signal Transducing/metabolism, Amino Acid Motifs, MESH: Tumor Suppressor Proteins/genetics, Gene Expression, Peptide, Biochemistry, MESH: Amino Acid Motifs, 0302 clinical medicine, MESH: Adaptor Proteins, Signal Transducing/genetics, MESH: Nuclear Magnetic Resonance, Biomolecular, Protein Isoforms, Cloning, Molecular, MESH: tau Proteins/chemistry, chemistry.chemical_classification, Neurons, biology, MESH: Kinetics, Chemistry, Nuclear Proteins, MESH: Neurons/metabolism, Nuclear magnetic resonance spectroscopy, MESH: Peptides/genetics, MESH: Tumor Suppressor Proteins/chemistry, MESH: tau Proteins/metabolism, Recombinant Proteins, MESH: Tumor Suppressor Proteins/metabolism, MESH: Recombinant Proteins/chemistry, MESH: tau Proteins/genetics, MESH: Peptides/metabolism, Domain (ring theory), MESH: Protein Conformation, beta-Strand, MESH: Protein Isoforms/metabolism, MESH: Models, Molecular, MESH: Nuclear Proteins/genetics, Protein Binding, Gene isoform, MESH: Recombinant Proteins/metabolism, MESH: Gene Expression, MESH: Sequence Alignment, tau Proteins, MESH: Escherichia coli/genetics, Clathrin, Protein–protein interaction, MESH: Peptides/chemistry, 03 medical and health sciences, Escherichia coli, Humans, MESH: Protein Binding, Protein Interaction Domains and Motifs, MESH: Adaptor Proteins, Signal Transducing/chemistry, MESH: Recombinant Proteins/genetics, MESH: Cloning, Molecular, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Nuclear Proteins/metabolism, Molecular Biology, Gene, Nuclear Magnetic Resonance, Biomolecular, Adaptor Proteins, Signal Transducing, MESH: Protein Conformation, alpha-Helical, MESH: Protein Interaction Domains and Motifs, Binding Sites, MESH: Protein Isoforms/genetics, MESH: Humans, Sequence Homology, Amino Acid, Tumor Suppressor Proteins, Cell Biology, MESH: Nuclear Proteins/chemistry, Kinetics, MESH: Neurons/chemistry, 030104 developmental biology, MESH: Binding Sites, MESH: Protein Isoforms/chemistry, Biophysics, biology.protein, MESH: Escherichia coli/metabolism, Protein Conformation, beta-Strand, Peptides, Sequence Alignment, 030217 neurology & neurosurgery
وصف الملف: application/octet-stream
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6
المؤلفون: Claude Alain Maurage, Antoine Ghestem, S. Bombois, Hervé Drobecq, Vincent Deramecourt, Florence Lebert, Florence Pasquier, Eugeen Vanmechelen, André Delacourte
المساهمون: Neuroendocrinologie et physiopathologie neuronale, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Troubles cognitifs vasculaires et dégénératifs - EA 2691 (TCDV), Université de Lille, Droit et Santé, Synthèse, structure et fonction des biomolécules (SSFB), Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), INNOGENETICS N.V, This work was supported by the integrated project APOPIS (Abnormal Proteins in the Pathogenesis of Neurodegenerative Disorders) funded by the European Community under the sixth framework program., The authors thank Innogenetics for the gift of alpha-synuclein antibody Syn1b (3B5) and recombinant alpha-synuclein.
المصدر: Journal of Neuropathology and Experimental Neurology
Journal of Neuropathology and Experimental Neurology, Lippincott, Williams & Wilkins, 2006, 65 (3), pp.278-288. ⟨10.1097/01.jnen.0000205145.54457.ea⟩مصطلحات موضوعية: Male, MESH: Lewy Body Disease/pathology, Pathology, Dementia with Lewy bodies, MESH: Alzheimer Disease/pathology, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Mass Spectrometry, Amyloid beta-Protein Precursor, chemistry.chemical_compound, MESH: Aged, 80 and over, 0302 clinical medicine, MESH: alpha-Synuclein/metabolism, MESH: Parkinson Disease/metabolism, Amyloid precursor protein, Electrophoresis, Gel, Two-Dimensional, Senile plaques, MESH: Amyloid beta-Protein Precursor/metabolism, Aged, 80 and over, Cerebral Cortex, MESH: Aged, 0303 health sciences, MESH: Middle Aged, biology, MESH: Parkinson Disease/pathology, Parkinson Disease, MESH: tau Proteins/metabolism, General Medicine, Middle Aged, MESH: Cerebral Cortex/metabolism, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], 3. Good health, Neurology, Female, Tauopathy, Alzheimer disease, Alzheimer's disease, Lewy Body Disease, Amyloid, medicine.medical_specialty, tau Proteins, Neuropathology, MESH: Cerebral Cortex/anatomy & histology, Pathology and Forensic Medicine, Alpha-synuclein, 03 medical and health sciences, Cellular and Molecular Neuroscience, mental disorders, medicine, Humans, MESH: Alzheimer Disease/metabolism, Aged, 030304 developmental biology, MESH: Mass Spectrometry, MESH: Humans, MESH: Lewy Body Disease/metabolism, business.industry, MESH: Electrophoresis, Gel, Two-Dimensional, medicine.disease, MESH: Male, nervous system diseases, chemistry, biology.protein, Neurology (clinical), MESH: Cerebral Cortex/pathology, business, MESH: Female, Biomarkers, 030217 neurology & neurosurgery