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المؤلفون: Aymeric Silvin, Pierre-Emmanuel Joubert, Jacob-Sebastian Seeler, Ido Amit, Joao G. Magalhaes, Nicolas Manel, Jack-Christophe Cossec, Anne Dejean, Adrien Decque, Olivier Joffre, Ronnie Blecher-Gonen, Sebastian Amigorena, Pierre Lapaquette, Matthew L. Albert
المساهمون: Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité et cancer (U932), Université Paris Descartes - Paris 5 (UPD5)-Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Weizmann Institute of Science [Rehovot, Israël], Immunobiologie des Cellules Dendritiques, Supported by Institut National du Cancer (PLBIO13-057 to S.A.), Agence Nationale de la Recherche (ANR-14-CE16 to S.A.), Ligue Nationale Contre le Cancer (Equipes labellisées, A. Dejean and S.A.), Fondation pour la Recherche Médicale (FRM, AJE201212 to O.J.), Région-Midi-Pyrénées (NVEQ 2014 to O.J.), European Research Council ('SUMOSTRESS' to A. Dejean, 'DC-BIOX340046' to S.A., and 'HIVINNATE' (309848) to N.M.), Ecole Normale Supérieure (A. Decque) and Odyssey-RE (A. Decque)., We thank M. Dasso (US National Institutes of Health) for antibody to SUMO-2, A. Garcia-Sastre(Icahn School of Medicine at Mount Sinai) for antibody to HA, A. Andrieux and J.-M. Carpier for technical help, Philippe Sansonetti (Pasteur Institute, Paris) for S. flexneri, and M. Yaniv for critical reading of the manuscript. Sequencing was performed by the Institut Génétique Biologie Moléculaire Cellulaire Microarray and Sequencing platform, a member of the 'France Génomique' consortium (ANR-10-INBS-0009)., ANR-14-CE16-0014,IS-Therapeutics,Caractérisation des cibles du domaine immunosuppresseur des envelopes rétrovirales: récepteur et voies de signalisation/ nouvelles approches thérapeutiques(2014), European Project: 294341,EC:FP7:ERC,ERC-2011-ADG_20110310,SUMOSTRESS(2013), European Project: 309848,EC:FP7:ERC,ERC-2012-StG_20111109,HIVINNATE(2013), European Project: 340046,EC:FP7:ERC,ERC-2013-ADG,DCBIOX(2014), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Organisation Nucléaire et Oncogenèse, Université Paris Descartes - Paris 5 (UPD5)-Institut Curie-Institut National de la Santé et de la Recherche Médicale (INSERM), Weizmann Institute of Science
المصدر: Nature Immunology
Nature Immunology, 2016, 17 (2), pp.140-149. ⟨10.1038/ni.3342⟩
Nature Immunology, Nature Publishing Group, 2016, 17 (2), pp.140-149. ⟨10.1038/ni.3342⟩مصطلحات موضوعية: Lipopolysaccharides, 0301 basic medicine, MESH: Chromatin/genetics, MESH: Signal Transduction, MESH: Immunity, Innate, medicine.medical_treatment, SUMO protein, Receptor, Interferon alpha-beta, MESH: Inflammation/genetics, MESH: Mice, Knockout, Mice, Interferon, MESH: Shock, Septic/immunology, Immunology and Allergy, MESH: Animals, Regulatory Elements, Transcriptional, Disease Resistance, MESH: Dendritic Cells/metabolism, Mice, Knockout, Toll-Like Receptors, MESH: Gene Expression Regulation, Pattern recognition receptor, MESH: Inflammation/metabolism, Shock, Septic, Chromatin, Cell biology, Enhancer Elements, Genetic, Cytokine, MESH: Dendritic Cells/immunology, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, Disease Susceptibility, Inflammation Mediators, medicine.symptom, Signal transduction, MESH: SUMO-1 Protein/metabolism, MESH: Inflammation Mediators/metabolism, Protein Binding, Signal Transduction, medicine.drug, Pattern recognition receptors, MESH: Sumoylation*/genetics, MESH: Toll-Like Receptors/metabolism, MESH: Inflammation/virology, SUMO-1 Protein, Immunology, MESH: Chromatin/metabolism, MESH: Sumoylation*/immunology, MESH: Disease Susceptibility, Inflammation, Biology, MESH: Immunomodulation, MESH: Genetic Loci, MESH: Lipopolysaccharides/immunology, Proinflammatory cytokine, Immunomodulation, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Regulatory Elements, Transcriptional, medicine, Animals, Gene silencing, MESH: Protein Binding, MESH: Receptor, Interferon alpha-beta/metabolism, MESH: Mice, Gene Expression Profiling, MESH: Shock, Septic/genetics, Sumoylation, Dendritic Cells, Interferon-beta, MESH: Interferon-beta/metabolism, MESH: Shock, Septic/metabolism, Immunity, Innate, Disease Models, Animal, Gene regulation in immune cells, MESH: Inflammation/immunology, 030104 developmental biology, MESH: Disease Resistance, Gene Expression Regulation, Genetic Loci, MESH: Enhancer Elements, Genetic, MESH: Cytokines/metabolism, MESH: Disease Models, Animal
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المؤلفون: Isabelle Angers, Stephen J. Galli, Adam Flaczyk, Salman T. Qureshi, Lothar Vogel, Ingo Spreitzer, Nicolas Gaudenzio, Sonja Wolfheimer, Stefan Schülke, B. Löschner, Mindy Tsai, Stephan Scheurer, Stefan Vieths
المساهمون: Paul-Ehrlich-Institute - Federal Institute for Vaccines and Biomedicines (EPI), Stanford University, McGill University Health Center [Montreal] (MUHC), German Research Foundation (DFG SCHU2951/1-1, SCHE637/3)
المصدر: Allergy
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩مصطلحات موضوعية: Lipopolysaccharides, Lipopolysaccharide, medicine.medical_treatment, Monophosphoryl Lipid A, MESH: Lipopolysaccharides / pharmacology, MESH: Mast Cells / metabolism, MESH: Monocytes / immunology, MESH: Dendritic Cells / drug effects, MESH: Mice, Knockout, Monocytes, MESH: Th2 Cells / immunology, chemistry.chemical_compound, Mice, Immunology and Allergy, MESH: Animals, Mast Cells, [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology, MESH: Dendritic Cells / metabolism, MESH: Lipid A / analogs & derivatives, Mice, Knockout, B-Lymphocytes, lipopolysaccharide, MESH: Mast Cells / drug effects, MESH: Inflammation Mediators / metabolism, Shock, Septic, MESH: Mast Cells / immunology, 3. Good health, MESH: B-Lymphocytes / immunology, MESH: B-Lymphocytes / metabolism, medicine.anatomical_structure, Lipid A, MESH: Epithelial Cells / metabolism, MESH: Adaptor Proteins, Vesicular Transport / genetics, MESH: Lipopolysaccharides / immunology, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, MESH: Dendritic Cells / immunology, Inflammation Mediators, MESH: Shock, Septic / immunology, MESH: Antigens / immunology, Immunology, monophosphoryl lipid A, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, MESH: Monocytes / drug effects, Immune system, Th2 Cells, adjuvant, MESH: Monocytes / metabolism, MESH: Adaptor Proteins, Vesicular Transport / metabolism, medicine, Animals, Humans, Secretion, MESH: Shock, Septic / metabolism, Antigens, MESH: Mice, MESH: Lipid A / immunology, MESH: Humans, MESH: Th2 Cells / metabolism, Monocyte, Epithelial Cells, Immunotherapy, Dendritic Cells, allergy, MESH: Lipid A / pharmacology, Adaptor Proteins, Vesicular Transport, Disease Models, Animal, chemistry, TLR4, MESH: Cytokines / biosynthesis, Cytokine secretion, MESH: Disease Models, Animal, MESH: Shock, Septic / genetics