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المؤلفون: Blaise Li, Martino Ugolini, Damarys Loew, Germano Cecere, Aleksei Samolygo, Céline Didier, Eric Cornes, Meetali Singh, Giorgia Barucci, Piergiuseppe Quarato, Florent Dingli
المساهمون: Mécanismes de l'Hérédité épigénétique / Mechanisms of epigenetic inheritance, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Scuola Normale Superiore di Pisa (SNS), Moscow Institute of Physics and Technology [Moscow] (MIPT), Laboratoire de Spectrométrie de Masse Protéomique, Institut Curie [Paris], This project has received funding from the Institut Pasteur, the CNRS and the European Research Council (ERC) under the EU Horizon 2020 research and innovation programme under grant agreement no. ERC-StG- 679243. G.B. is part of the Pasteur–Paris University (PPU) International PhD Program and has received funding from the EU Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 665807. E.C. was supported by a Pasteur-Cantarini Fellowship program. F.D. and D.L. have received funding from Région Ile-de-France and Fondation pour la Recherche Médicale grants to support this study, We thank the members of the Cecere laboratory, D. Canzio, N. Iovino, R. Sawarkar and P. Andersen for discussions of the manuscript, the Miska, the Mello, the Kennedy, the Seydoux, the Claycomb, the Strome and the Dumont laboratories for sharing strains and/or antibodies. Some strains were provided by the CGC, funded by NIH Office of Research Infrastructure Programs (P40 OD010440)., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Nature cell biology
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (2), pp.235-245. ⟨10.1038/s41556-020-0462-7⟩
Nature Cell Biology, 2020, 22 (2), pp.235-245. ⟨10.1038/s41556-020-0462-7⟩مصطلحات موضوعية: MESH: Gene Editing, MESH: CRISPR-Cas Systems, Small RNA, MESH: Argonaute Proteins / deficiency, MESH: Caenorhabditis elegans Proteins / metabolism, Inheritance Patterns, MESH: RNA, Small Interfering / genetics, MESH: Argonaute Proteins / metabolism, medicine.disease_cause, MESH: RNA, Antisense / genetics, MESH: Argonaute Proteins / genetics, Animals, Genetically Modified, Histones, 0302 clinical medicine, MESH: Histones / metabolism, MESH: Animals, RNA, Small Interfering, MESH: Caenorhabditis elegans / genetics, Caenorhabditis elegans, Gene Editing, 0303 health sciences, Mutation, MESH: RNA, Messenger / metabolism, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Biological Evolution, Cell biology, Histone, MESH: Fertility / genetics, 030220 oncology & carcinogenesis, Argonaute Proteins, Piwi RNAs, MESH: RNA, Messenger / genetics, MESH: Gene Silencing, Epigenetic memory, endocrine system, MESH: Mutation, MESH: Caenorhabditis elegans / metabolism, Piwi-interacting RNA, MESH: Biological Evolution, Biology, Article, MESH: Animals, Genetically Modified, 03 medical and health sciences, medicine, Animals, Gene silencing, RNA, Antisense, Gene Silencing, RNA, Messenger, MESH: RNA, Antisense / metabolism, Caenorhabditis elegans Proteins, Gene, Repetitive Sequences, Nucleic Acid, 030304 developmental biology, MESH: RNA, Small Interfering / metabolism, MESH: Repetitive Sequences, Nucleic Acid, MESH: Histones / genetics, urogenital system, RNA, Cell Biology, biology.organism_classification, Fertility, RNAi, biology.protein, MESH: Caenorhabditis elegans Proteins / genetics, MESH: Inheritance Patterns, CRISPR-Cas Systems
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المؤلفون: Alain Fournier, Pascal Cosette, David Vaudry, Magalie Bénard, Béatrice Botia, Aurélia Ravni, Bruno J. Gonzalez, Anthony Falluel-Morel, Damien Seyer, Hubert Vaudry, Thierry Jouenne
المساهمون: Institut Fédératif de Recherches Multidisciplinaires sur les Peptides (IFRMP 23), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Lutte Contre le Cancer Henri Becquerel Normandie Rouen (CLCC Henri Becquerel)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Université Le Havre Normandie (ULH), Normandie Université (NU)-CHU Rouen, Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS), International Associated laboratory Samuel de Champlain, Institut National de la Recherche Scientifique [Québec] (INRS)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Neuroendocrinologie cellulaire et moléculaire, Université de Rouen Normandie (UNIROUEN), Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), This work was supported by INSERM (U413), the European Institute for Peptide Research (IFRMP23), the Institut de Recherches Scientifiques sur les Boissons (IREB), an Interreg 3A FEDER project, the ANR (06-JCJC-0071), and the Conseil Régional de Haute-Normandie. The work was conducted with the technical support of the proteomic facility of the IFRMP23 and the Platform for Cell Imaging of Haute-Normandie. BB was a recipient of a doctoral fellowship from the Société Française d’Alcoologie and a fellowship from the Fondation pour la Recherche Médicale. We thank Dr Mickaël Naassila for the quantification of ethanol level in blood samples.
المصدر: Journal of Molecular Neuroscience
Journal of Molecular Neuroscience, Humana Press, 2008, 36 (1-3), pp.61-72. ⟨10.1007/s12031-008-9075-5⟩مصطلحات موضوعية: Small interfering RNA, [SDV]Life Sciences [q-bio], MESH: RNA, Small Interfering/genetics, MESH: Cerebellum/cytology, MESH: Amino Acid Sequence, 0302 clinical medicine, Cerebellum, MESH: Animals, RNA, Small Interfering, Cells, Cultured, MESH: Neurons/cytology, Neurons, 0303 health sciences, biology, medicine.diagnostic_test, Caspase 3, MESH: Pituitary Adenylate Cyclase-Activating Polypeptide/metabolism, General Medicine, respiratory system, 3. Good health, Neuroprotective Agents, MESH: Colforsin/metabolism, Pituitary Adenylate Cyclase-Activating Polypeptide, Tetradecanoylphorbol Acetate, hormones, hormone substitutes, and hormone antagonists, MESH: Cells, Cultured, Neurotrophin, endocrine system, MESH: Rats, Molecular Sequence Data, MESH: Neuroprotective Agents/metabolism, Adenylate kinase, Peroxiredoxin 2, Neuroprotection, MESH: Peroxiredoxins/metabolism, MESH: Ethanol/metabolism, 03 medical and health sciences, Cellular and Molecular Neuroscience, Western blot, MESH: Peroxiredoxins/genetics, medicine, Animals, Amino Acid Sequence, Rats, Wistar, Protein kinase C, 030304 developmental biology, MESH: Molecular Sequence Data, Ethanol, Colforsin, MESH: Neurons/metabolism, Peroxiredoxins, MESH: Rats, Wistar, Molecular biology, Rats, MESH: Tetradecanoylphorbol Acetate/metabolism, MESH: RNA, Small Interfering/metabolism, biology.protein, MESH: Pituitary Adenylate Cyclase-Activating Polypeptide/genetics, MESH: Caspase 3/metabolism, 030217 neurology & neurosurgery
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المؤلفون: Nathalie Coolen, Virginie Prulière-Escabasse, Pierre-Régis Burgel, Daniel Dusser, Estelle Escudier, André Coste, Yongzheng Wu, Isabelle Fajac, Lhousseine Touqui, Guiti Thévenot, Clémence Martin, Jean-François Papon
المساهمون: Service de pneumologie [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5), Défense innée et inflammation, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Service d'ORL [Créteil], Centre Hospitalier Intercommunal de Créteil (CHIC), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-IFR10, CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Physiopathologie des maladies génétiques d'expression pédiatrique, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Physiologie et Explorations Fonctionnelles [Cochin APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), This work was funded by grants from Chancellerie des Universités de Paris (Legs Poix), Association Vaincre la Mucoviscidose and Association Cardif., The authors thank Sophie Danel-Beaucaire (Cochin Hospital, Paris, France) for help with immunohistochemical staining and Claire Danel (Bichat Hospital, Paris, France) for providing human CF tissues., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Wu, Yongzheng
المصدر: European Respiratory Journal
European Respiratory Journal, European Respiratory Society, 2013, 42 (6), pp.1553-1562. ⟨10.1183/09031936.00164212⟩
European Respiratory Journal, 2013, 42 (6), pp.1553-1562. ⟨10.1183/09031936.00164212⟩مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Pathology, Cystic Fibrosis, Angiogenesis, medicine.medical_treatment, Cystic Fibrosis Transmembrane Conductance Regulator, MESH: Trachea / metabolism, Cystic fibrosis, Tyrosine-kinase inhibitor, Epithelium, chemistry.chemical_compound, Mice, 0302 clinical medicine, MESH: Cystic Fibrosis Transmembrane Conductance Regulator / physiology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Lung / blood supply, MESH: Animals, MESH: Cystic Fibrosis / physiopathology, Epidermal growth factor receptor, MESH: Cystic Fibrosis / genetics, Phosphorylation, RNA, Small Interfering, Lung, Aorta, Cells, Cultured, 0303 health sciences, biology, MESH: Gene Expression Regulation, MESH: Bronchi / metabolism, respiratory system, 3. Good health, Vascular endothelial growth factor, ErbB Receptors, Trachea, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Mice, Inbred CFTR, MESH: Cells, Cultured, Pulmonary and Respiratory Medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, MESH: Mice, Transgenic, medicine.drug_class, MESH: Aorta / pathology, MESH: ErbB Receptors / metabolism, Bronchi, Mice, Transgenic, Cell Line, 03 medical and health sciences, medicine, Animals, Humans, Mice, Inbred CFTR, MESH: Mice, 030304 developmental biology, MESH: RNA, Small Interfering / metabolism, MESH: Humans, MESH: Phosphorylation, business.industry, Growth factor, MESH: Vascular Endothelial Growth Factor A / metabolism, medicine.disease, MESH: Cystic Fibrosis Transmembrane Conductance Regulator / genetics, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Epithelium / metabolism, MESH: Cell Line, respiratory tract diseases, Transplantation, 030228 respiratory system, chemistry, Gene Expression Regulation, Cancer research, biology.protein, Respiratory epithelium, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, business
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المؤلفون: Pascal Miesen, Koen W. R. van Cleef, Maria-Carla Saleh, Nicolas Vodovar, Alfred W. Bronkhorst, Ronald P. van Rij, Hervé Blanc
المساهمون: Virus et Interférence ARN - Viruses and RNA Interference, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Department of Microbiology and Immunology, Radboud University Medical Center [Nijmegen], This work was financially supported by the French Agence Nationale de la Recherche (ANR-09-394 JCJC-0045-01) and the European Research Council (FP7/2007-2013 ERC 242703) to M.C.S., and a VIDI fellowship from the Netherlands Organization for Scientific Research (project number 864.08.003) and Horizon Breakthrough fellowship from the Netherlands Genomics Initiative (project number 93519018) to RPvR., ANR-09-JCJC-0045,VIA(2009), European Project: 242703,EC:FP7:ERC,ERC-2009-StG,ANTIVIRALRNAI(2009), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: PLoS One, 7
PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (1), pp.e30861. ⟨10.1371/journal.pone.0030861.t001⟩
PLoS ONE, 2012, 7 (1), pp.e30861. ⟨10.1371/journal.pone.0030861.t001⟩
PLoS ONE, Vol 7, Iss 1, p e30861 (2012)
PLoS One, 7, 1مصطلحات موضوعية: Small interfering RNA, MESH: Gene Amplification*/physiology, MESH: DNA Transposable Elements/physiology, viruses, MESH: RNA, Small Interfering/genetics, MESH: Base Sequence, Biochemistry, MESH: Arboviruses/genetics, arboviral infections, Aedes, RNA interference, Nucleic Acids, Molecular Cell Biology, SiRNA, MESH: Arbovirus Infections/virology, MESH: Animals, RNA, Small Interfering, MESH: Gene Amplification*/genetics, Cells, Cultured, MESH: Culicidae/virology, Genetics, 0303 health sciences, Multidisciplinary, 3. Good health, Antisense RNA, Insects, MESH: Culicidae/genetics, MESH: Virus Integration/genetics, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Medicine, MESH: Arboviruses/physiology, MESH: Aedes/cytology, Research Article, MESH: Cells, Cultured, Transposable element, endocrine system, Science, Virus Integration, Piwi-interacting RNA, mosquito, Aedes aegypti, Arbovirus Infections, Biology, Microbiology, Arbovirus, MESH: Gene Expression Profiling, 03 medical and health sciences, medicine, Animals, 030304 developmental biology, Base Sequence, MESH: Aedes/virology, 030306 microbiology, urogenital system, Gene Expression Profiling, fungi, Immunity, Gene Amplification, RNA, Pathogenesis and modulation of inflammation Infection and autoimmunity [N4i 1], biology.organism_classification, medicine.disease, MESH: Aedes/genetics, Culicidae, MESH: RNA, Small Interfering/metabolism, MESH: Arbovirus Infections/genetics, DNA Transposable Elements, Arboviruses
وصف الملف: application/pdf