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المؤلفون: Domenichini, Florence, Terrié, Elodie, Arnault, Patricia, Harnois, Thomas, Magaud, Christophe, Bois, Patrick, Constantin, Bruno, Coronas, Valérie
المساهمون: Signalisation et Transports Ioniques Membranaires (STIM Poitiers ), Université de Poitiers = University of Poitiers (UP)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), This work was supported by La Ligue contre le cancer Grand Ouest Comités de la Vienne et des Deux Sèvres, Région Poitou-Charentes, FEDER HABISAN and ACI from Université de Tours et de Poitiers. E. Terrié holds a PhD fellowship from Région Nouvelle-Aquitaine.
المصدر: ISSN: 1066-5099 ; STEM CELLS ; https://hal.science/hal-01705161 ; STEM CELLS, 2018, 36 (5), pp.761-774. ⟨10.1002/stem.2786⟩.
مصطلحات موضوعية: Stem cells, Stem cell-microenvironment interactions, Calcium flux, Nervous system, Adult stem cells, Stem cell asymmetry, Neural stem cell, Neurogenesis/neural regeneration, Stem cell niche, Self-renewal, MESH: Adult Stem Cells, MESH: Calcium Signaling, MESH: Animals, MESH: Cell Proliferation, MESH: Cell Self Renewal, MESH: Mice Inbred C57BL, MESH: Neural Stem Cells, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Relation: info:eu-repo/semantics/altIdentifier/pmid/29359518; hal-01705161; https://hal.science/hal-01705161; https://hal.science/hal-01705161/document; https://hal.science/hal-01705161/file/Domenichini_et_al-2018-STEM_CELLS.pdf; PUBMED: 29359518
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المؤلفون: Ira Fleming, Carolyn Winston, Benjamin Kruft, Alex K. Shalek, Wolfram Goessling, Satdarshan P.S. Monga, Florian Mueller, Sungjin Ko, Udayan Apte, Chad Walesky, Kellie E. Kolb, Jake Henderson
المساهمون: Brigham and Women’s Hospital [Boston, MA], Harvard Medical School [Boston] (HMS), Institute of Medical Engineering & Science [Cambridge, MA] (IMES), Massachusetts Institute of Technology (MIT), Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Ragon Institute of MGH, MIT and Harvard, Koch Institute for Integrative Cancer Research at MIT [Cambridge, MA], University of Pittsburgh Medical Center [Pittsburgh, PA, États-Unis] (UPMC), Imagerie et Modélisation - Imaging and Modeling, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Department of Pharmacology, Toxicology, and Therapeutics [Kansas City, KS, USA], University of Kansas Medical Center [Kansas City, KS, USA], Harvard-MIT Division of Health Sciences and Technology [Cambridge], Dana-Farber Cancer Institute [Boston], Harvard Stem Cell Institute [Cambridge, USA] (HSCI), Harvard University, Massachusetts General Hospital [Boston, MA, USA], C..W. is supported by F32DK111151, the Cholangiocarcinoma Foundation Research Fellowship, and the American Liver Foundation Charles Trey, MD Memorial Post-doctoral Research Fellowship. W.G. is supported by R01DK090311, R01DK105198, R24OD017870, and the Claudia Adams Barr Program for Excellence in Cancer Research. W.G. is a Pew Scholar in Biomedical Sciences. A.K.S. was supported, in part, by the Searle Scholars Program, the Beckman Young Investigator Program, a Sloan Fellowship in Chemistry, the NIH (1DP2GM1194192 & RM1HG0061931), and the MIT Stem Cell Initiative through Fondation MIT. U.A. is supported by R01DK098414. S.P.M is supported by NIH/NIDDK P30DK120531, Pittsburgh Liver Research Centre Grant, and NIH/NIDDK (DK62277, DK100287, and CA204586)
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩مصطلحات موضوعية: 0301 basic medicine, MESH: beta Catenin, General Physics and Astronomy, MESH: Cell Cycle, MESH: Mice, Knockout, Biochemistry, Transcriptome, MESH: Hepatocytes, Mice, 0302 clinical medicine, Protein biosynthesis, MESH: Animals, lcsh:Science, Wnt Signaling Pathway, beta Catenin, Mice, Knockout, Multidisciplinary, Fluorescence in situ hybridization, Cell Cycle, MESH: Wnt Signaling Pathway, Wnt signaling pathway, Cell cycle, MESH: Hepatectomy, Liver regeneration, Cell biology, MESH: Wnt Proteins, Liver, 030211 gastroenterology & hepatology, MESH: Liver Regeneration, Reprogramming, Biotechnology, Science, MESH: Acetaminophen, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Mice, Inbred C57BL, MESH: Cell Proliferation, Detoxification, Genetics, Animals, Hepatectomy, Transcriptomics, MESH: Mice, Molecular Biology, Acetaminophen, Cell Proliferation, Mechanism (biology), Gene Expression Profiling, Macrophages, MESH: Macrophages, General Chemistry, Regenerative process, Liver Regeneration, Gene expression profiling, Mice, Inbred C57BL, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, Hepatocytes, lcsh:Q, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Liver function, MESH: Disease Models, Animal, MESH: Liver
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المؤلفون: Matthieu Ribon, Lorenzo Schiaffino, Christian S Lobsiger, Michel Mallat, Pierre de la Grange, Félix Berriat, Danielle Seilhean, Delphine Bohl, Charlène Iltis, Séverine Boillée, Aude Chiot, Sakina Zaïdi, Ariane Jolly, Stéphanie Millecamps
المساهمون: Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Verona = University of Verona (UNIVR), GenoSplice [Paris], Département de Neuropathologie, APHP, Hôpital Pitié-Salpêtrière, Paris, France., CHIOT, Aude
المصدر: Nature Neuroscience
Nature Neuroscience, 2020, 23 (11), pp.1339-1351. ⟨10.1038/s41593-020-00718-z⟩مصطلحات موضوعية: 0301 basic medicine, Therapeutic gene modulation, MESH: Axons, Myeloid, MESH: Mice, Transgenic, [SDV]Life Sciences [q-bio], Cell, Proinflammatory cytokine, MESH: Spinal Cord, 03 medical and health sciences, 0302 clinical medicine, MESH: Mice, Inbred C57BL, medicine, MESH: Animals, Amyotrophic lateral sclerosis, MESH: Amyotrophic Lateral Sclerosis, MESH: Aged, MESH: Middle Aged, MESH: Humans, Microglia, Chemistry, General Neuroscience, Neurodegeneration, MESH: Macrophages, MESH: Adult, medicine.disease, MESH: Male, Cell biology, MESH: Microglia, [SDV] Life Sciences [q-bio], MESH: Sciatic Nerve, 030104 developmental biology, medicine.anatomical_structure, Sciatic nerve, MESH: Female, Neuroscience, MESH: Motor Neurons, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Dimitri Belenki, José Américo N L F de Freitas, Utz Herbig, Maja Milanovic, Oliver Bischof, Jesús Gil, Pierre-François Roux, Bin Sun, Gregory J. Dore, Clemens A. Schmitt, Ricardo Iván Martínez-Zamudio, Lucas Robinson
المساهمون: Institut Pasteur [Paris] (IP), MRC London Institute of Medical Sciences (LMC), Imperial College London, R.I.M.-Z. was supported by La Ligue Nationale Contre le Cancer and is a Mexican National Scientific and Technology Council (CONACYT) and Mexican National Researchers System (SNI) fellow. L.R. was supported by the Pasteur–Paris University (PPU) International Ph.D. Program and by the Fondation pour la Recherche Médicale (FRM). J.A.N.L.F.d.F. was supported by La Ligue Nationale Contre le Cancer. J.G. was supported by the Medical Research Council (MRC, MC_U120085810) and by a grant from Worldwide Cancer Research (WCR, 18-0215). O.B. was supported by the Pasteur–Weizmann Foundation, ANR–BMFT, the Fondation ARC pour la recherche sur le Cancer, La Ligue Nationale Contre le Cancer and INSERM–AGEMED. Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under award number R01CA136533., Institut Pasteur [Paris]
المصدر: Nat Cell Biol
Nature Cell Biology
Nature Cell Biology, 2020, 22 (7), pp.842-855. ⟨10.1038/s41556-020-0529-5⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (7), pp.842-855. ⟨10.1038/s41556-020-0529-5⟩مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Epigenesis, Genetic, Histones, 0302 clinical medicine, CHROMATIN IMMUNOPRECIPITATION, MESH: Animals, MESH: Epigenesis, Genetic, 11 Medical and Health Sciences, Epigenesis, MESH: Histones, Regulation of gene expression, 0303 health sciences, CELLULAR SENESCENCE, MESH: Gene Expression Regulation, MESH: Transcription Factor AP-1, Chromatin, Cell biology, 030220 oncology & carcinogenesis, Female, Life Sciences & Biomedicine, EXPRESSION, Senescence, PROTEINS, Biology, Article, MESH: Chromatin, 03 medical and health sciences, MESH: Mice, Inbred C57BL, Animals, Humans, Epigenetics, Enhancer, Transcription factor, JUN, 030304 developmental biology, MESH: Humans, Science & Technology, LANDSCAPE, MESH: Transcriptome, MESH: Cellular Senescence, Cell Biology, Epigenome, Fibroblasts, 06 Biological Sciences, Mice, Inbred C57BL, Transcription Factor AP-1, ENHANCERS, Gene Expression Regulation, MESH: Fibroblasts, Transcriptome, MESH: Female, Developmental Biology
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المؤلفون: Blanquart, Eve, Mandonnet, Audrey, Mars, Marion, Cenac, Claire, Anesi, Nina, Mercier, Pascale, Audouard, Christophe, Roga, Stephane, Serrano de Almeida, Gilberto, Bevan, Charlotte, Girard, Jean-Philippe, Pelletier, Lucette, Laffont, Sophie, Guéry, Jean-Charles
المساهمون: Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de pharmacologie et de biologie structurale (IPBS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Centre de biologie du développement (CBD), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Imperial College London, laffont-pradines, sophie, Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, CNRS, INSERM, UPS, Toulouse, France. (Infinity), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Université Fédérale Toulouse Midi-Pyrénées
المصدر: Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2022, 149 (1), pp.237-251.e12. ⟨10.1016/j.jaci.2021.04.029⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2021, ⟨10.1016/j.jaci.2021.04.029⟩مصطلحات موضوعية: Male, KLRG1, MESH: Signal Transduction, [SDV.IMM] Life Sciences [q-bio]/Immunology, MESH: Lung / pathology, androgen signaling, MESH: Mice, Knockout, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, ILC2, MESH: Testosterone / pharmacology, MESH: Pneumonia / immunology, MESH: Mice, Inbred C57BL, Animals, Lectins, C-Type, Testosterone, Sex differences in asthma, MESH: Animals, Lymphocytes, MESH: Pneumonia / pathology, Receptors, Immunologic, [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology, Lung, [SDV.IMM.II] Life Sciences [q-bio]/Immunology/Innate immunity, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, Sex Characteristics, lung inflammation, MESH: Androgens / pharmacology, Pneumonia, MESH: Lung / immunology, Interleukin-33, MESH: Receptors, Immunologic / immunology, MESH: Male, Mice, Inbred C57BL, MESH: Lymphocytes / immunology, MESH: Lectins, C-Type / immunology, MESH: Interleukin-33 / immunology, Androgens, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, MESH: Female, [SDV.IMM.ALL] Life Sciences [q-bio]/Immunology/Allergology, Signal Transduction, MESH: Sex Characteristics
وصف الملف: application/pdf
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المؤلفون: Scekic-Zahirovic, Jelena, Sanjuan-Ruiz, Inmaculada, Kan, Vanessa, Megat, Salim, De Rossi, Pierre, Dieterlé, Stéphane, Cassel, Raphaelle, Jamet, Marguerite, Kessler, Pascal, Wiesner, Diana, Tzeplaeff, Laura, Demais, Valérie, Sahadevan, Sonu, Hembach, Katharina M, Muller, Hans-Peter, Picchiarelli, Gina, Mishra, Nibha, Antonucci, Stefano, Dirrig-Grosch, Sylvie, Kassubek, Jan, Rasche, Volker, Ludolph, Albert, Boutillier, Anne-Laurence, Roselli, Francesco, Polymenidou, Magdalini, Lagier-Tourenne, Clotilde, Liebscher, Sabine, Dupuis, Luc
المساهمون: Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ludwig-Maximilians University [Munich] (LMU), Universität Zürich [Zürich] = University of Zurich (UZH), Laboratoire de neurosciences cognitives et adaptatives (LNCA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), CRBS - Centre de Recherche en Biomédecine de Strasbourg (Inserm UMS38/UNISTRA), University of Ulm (UUlm), Deutsches Zentrum für Neurodegenerative Erkrankungen [Ulm] (DZNE), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Centre de Neurochimie, Harvard Medical School [Boston] (HMS), Harvard University [Cambridge], Munich Cluster for systems neurology [Munich] (SyNergy), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM)-Ludwig-Maximilians-Universität München (LMU), Université de Strasbourg Inserm Faculté de médecine, Klinikum der Universitat Munchen, Ludwig-Maximilians-Universität München (LMU), University hospital of Zurich [Zurich], Universität Ulm - Ulm University [Ulm, Allemagne], Massachusetts Institute of Technology (MIT), Ludwig-Maximilians University Hospital (LMU Munich), ANR-16-CE92-0031,EpiFUS,Rôle de FUS dans la régulation des modifications épigénétiques : conséquences pour la sclérose latérale amyotrophique et la démence frontotemporale(2016), ANR-16-CE16-0015,ToFU,Interactions entre TAU, FUS et TDP-43 dans les maladies neurodégénératives(2016), ANR-19-CE17-0016,SPREADALS,Propagation et toxicité des facteurs pathogéniques de la sclérose latérale amyotrophique(2019), Technische Universität München [München] (TUM)-Ludwig-Maximilians-Universität München (LMU), Anne Laurence, Boutillier, Rôle de FUS dans la régulation des modifications épigénétiques : conséquences pour la sclérose latérale amyotrophique et la démence frontotemporale - - EpiFUS2016 - ANR-16-CE92-0031 - AAPG2016 - VALID, Interactions entre TAU, FUS et TDP-43 dans les maladies neurodégénératives - - ToFU2016 - ANR-16-CE16-0015 - AAPG2016 - VALID, Propagation et toxicité des facteurs pathogéniques de la sclérose latérale amyotrophique - - SPREADALS2019 - ANR-19-CE17-0016 - AAPG2019 - VALID, University of Zurich, Liebscher, Sabine, Dupuis, Luc, Centre de Recherche en Biomédecine de Strasbourg (CRBS), Dieterle, Stéphane
المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3028. ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications 12(1), 3028 (2021). doi:10.1038/s41467-021-23187-9
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, 2021, 12 (1), pp.3028. ⟨10.1038/s41467-021-23187-9⟩مصطلحات موضوعية: Male, Cytoplasm, [SDV]Life Sciences [q-bio], General Physics and Astronomy, Gene Expression, Synaptic Transmission, MESH: Synapses, Mice, MESH: Animals, Gene Knock-In Techniques, MESH: Amyotrophic Lateral Sclerosis, MESH: Gene Knock-In Techniques, metabolism [RNA-Binding Protein FUS], Motor Neurons, MESH: RNA-Binding Protein FUS, FUS protein, mouse, 3100 General Physics and Astronomy, [SDV] Life Sciences [q-bio], genetics [Amyotrophic Lateral Sclerosis], Phenotype, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, ddc:500, MESH: Motor Neurons, MESH: Mutation, MESH: Gene Expression, Science, 610 Medicine & health, 1600 General Chemistry, Genetics and Molecular Biology, MESH: Phenotype, Article, 1300 General Biochemistry, Genetics and Molecular Biology, MESH: Mice, Inbred C57BL, MESH: Synaptic Transmission, Animals, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Mice, metabolism [Cytoplasm], metabolism [Amyotrophic Lateral Sclerosis], MESH: Cytoplasm, Amyotrophic Lateral Sclerosis, General Chemistry, metabolism [Motor Neurons], metabolism [Synapses], MESH: Male, Mice, Inbred C57BL, physiology [Synaptic Transmission], General Biochemistry, Mutation, Synapses, RNA-Binding Protein FUS, 11493 Department of Quantitative Biomedicine, genetics [RNA-Binding Protein FUS], MESH: Female
وصف الملف: application/pdf; 2021_NatureCummun.pdf - application/pdf
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المؤلفون: Rozier, Pauline, Maumus, Marie, Maria, Alexandre Thibault Jacques, Toupet, Karine, Jorgensen, Christian, Guilpain, Philippe, Noël, Danièle
المساهمون: Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de Rhumatologie [CHRU Montpellier], Salvy-Córdoba, Nathalie
المصدر: Cells
Volume 10
Issue 10
Cells, Vol 10, Iss 2727, p 2727 (2021)
Cells, MDPI, 2021, 10 (10), pp.2727. ⟨10.3390/cells10102727⟩مصطلحات موضوعية: MESH: Interferon-gamma, QH301-705.5, Pulmonary Fibrosis, Anti-Inflammatory Agents, exosomes, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, MESH: Scleroderma, Systemic, MESH: Immunosuppression Therapy, Article, Interferon-gamma, MESH: Skin, MESH: Mice, Inbred C57BL, MESH: Up-Regulation, Animals, MESH: Animals, scleroderma, MESH: Extracellular Vesicles, Biology (General), Skin, Immunosuppression Therapy, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, therapy, Scleroderma, Systemic, MESH: Pulmonary Fibrosis, Mesenchymal Stem Cells, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Up-Regulation, Mice, Inbred C57BL, MicroRNAs, MESH: Mesenchymal Stem Cells, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Anti-Inflammatory Agents, mesenchymal stromal cell, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy, extracellular vesicles, MESH: MicroRNAs, microvesicles
وصف الملف: application/pdf
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المؤلفون: Pires, Karla, Buffolo, Márcio, Pires, Karla Maria, Ferhat, Maroua, Ilkun, Olesya, Makaju, Aman, Achenbach, Alan, Bowman, Faith, Atkinson, Donald, Holland, William, Amri, Ez-Zoubir, Chaurasia, Bhagirath, Franklin, Sarah, Boudina, Sihem
المساهمون: Institut de Biologie Valrose (IBV), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Cell Reports, Vol 29, Iss 2, Pp 270-282.e5 (2019)
Cell Reports
Cell Reports, Elsevier Inc, 2019, 29 (2), pp.270-282.e5. ⟨10.1016/j.celrep.2019.08.092⟩مصطلحات موضوعية: MESH: Signal Transduction, 0301 basic medicine, MESH: Rosiglitazone, [SDV]Life Sciences [q-bio], visceral fat, MESH: Bone Morphogenetic Protein 4, Adipose tissue, Inflammation, MESH: Muscle, Smooth, MESH: Stem Cells, macromolecular substances, MESH: Phenotype, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Paracrine signalling, 0302 clinical medicine, Insulin resistance, adipose progenitors, MESH: Mice, Inbred C57BL, Fibrosis, medicine, MESH: Animals, MESH: Paracrine Communication, Progenitor cell, cell sorting, MESH: Intra-Abdominal Fat, lcsh:QH301-705.5, Chemistry, technology, industry, and agriculture, MESH: Antigens, CD34, medicine.disease, fat expansion, MESH: Male, humanities, Cell biology, MESH: Solubility, Transplantation, MESH: Insulin Resistance, 030104 developmental biology, MESH: Adipose Tissue, White, lcsh:Biology (General), MESH: Fibroblasts, Adipogenesis, MESH: Weight Gain, medicine.symptom, MESH: Adipogenesis, 030217 neurology & neurosurgery, transplantation
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المؤلفون: Alain Doucet, Geneviève Escher, Luciana Morla, Gabrielle Planelles, Dignê Tembely, Lydie Cheval, Christine Walter, Bruno Vogt, Gilles Crambert, Naziha Bakouh
المساهمون: Centre de Recherche des Cordeliers (CRC), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Métabolisme et physiologie rénales (ERL 8228), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Régulation des systèmes de transport dans les épithéliums (UMR_S467), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: American Journal of Physiology. Renal Physiology
American Journal of Physiology. Renal Physiology, 2019, 317 (2), pp.F435-F443. ⟨10.1152/ajprenal.00059.2019⟩مصطلحات موضوعية: metabolic acidosis, MESH: Signal Transduction, 0301 basic medicine, MESH: Hydrogen-Ion Concentration, MESH: Atrial Natriuretic Factor, Physiology, [SDV]Life Sciences [q-bio], Stimulation, MESH: Mice, Knockout, chemistry.chemical_compound, 0302 clinical medicine, Atrial natriuretic peptide, MESH: Sodium, MESH: Cyclic GMP, MESH: H(+)-K(+)-Exchanging ATPase, MESH: Animals, 610 Medicine & health, Aldosterone, Second messenger system, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, MESH: Rats, medicine.drug_class, H-K-ATPase, MESH: Acidosis, collecting duct, 03 medical and health sciences, MESH: Mice, Inbred C57BL, MESH: Xenopus laevis, Internal medicine, atrial natriuretic peptide, medicine, Intercalated Cell, MESH: Paracrine Communication, MESH: Kidney Tubules, Collecting, aldosterone, MESH: Aldosterone, Metabolic acidosis, medicine.disease, MESH: Adaptation, Physiological, cGMP, sodium secretion, MESH: Acid-Base Equilibrium, 030104 developmental biology, Endocrinology, chemistry, Mineralocorticoid, 570 Life sciences, biology, Cotransporter, MESH: Female, 030217 neurology & neurosurgery
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المساهمون: Lille Inflammation Research International Center - U 995 (LIRIC), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Johns Hopkins University (JHU), S.-E. A. is the recipient of a 'Université de Lille' fellowship. C.P. was the recipient of a 'Université Lille 2' fellowship., We thank J. Bara for the gift of the 45M1 antibody, M.H. Gevaert (Service Commun-Morphologie Cellulaire, Université de Lille) for the slides, J. Devassine and Y. Lepage from the EOPS animal facility (Université de Lille) for mouse colony management and S. Plet and M. Magnien (LIRIC) for genotyping and dissection and the Bio-imaging Center (plate-forme de microscopie photonique, Université Lille) for Carl Zeiss Axio Scan. Z1 scanner., Lille Inflammation Research International Center (LIRIC), Université de Lille, Inserm, CHU Lille, Lille Inflammation Research International Center - U 995 [LIRIC]
المصدر: Histochemistry and Cell Biology
Histochemistry and Cell Biology, Springer Verlag, 2019, Histochemistry and cell biology, 152, pp.167-174. ⟨10.1007/s00418-019-01785-5⟩
Histochemistry and Cell Biology, 2019, Histochemistry and cell biology, 152, pp.167-174. ⟨10.1007/s00418-019-01785-5⟩
Histochemistry and Cell Biology, Springer Verlag, 2019, 152, pp.167-174مصطلحات موضوعية: 0301 basic medicine, Glycosylation, [SDV]Life Sciences [q-bio], Mucin 5AC, MESH: Mucin 5AC/analysis, MESH: Respiratory Mucosa/cytology, MESH: Mice, Knockout, Mice, MESH: Animals, MESH: Mucin-5B/metabolism, Receptor, Muc5b, Nose, Mice, Knockout, biology, Chemistry, MESH: Mucin-5B/deficiency, MESH: Nasal Mucosa/chemistry, respiratory system, MESH: Glycosylation, Immunohistochemistry, Mucin-5B, 3. Good health, Cell biology, Medical Laboratory Technology, medicine.anatomical_structure, Mouse nose, MESH: Mucin 5AC/genetics, Muc5ac, MESH: Respiratory Mucosa/metabolism, Histology, Respiratory Mucosa, 03 medical and health sciences, MESH: Mice, Inbred C57BL, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Animals, Bowman’s gland, MESH: Mice, Molecular Biology, MESH: Nasal Mucosa/cytology, MESH: Nasal Mucosa/metabolism, Lamina propria, 030102 biochemistry & molecular biology, MESH: Mucin-5B/analysis, Mucin, Lectin, MESH: Immunohistochemistry, Cell Biology, Mucus, Mice, Inbred C57BL, Nasal Mucosa, 030104 developmental biology, biology.protein, Respiratory epithelium, MESH: Respiratory Mucosa/chemistry, MESH: Mucin 5AC/metabolism, Olfactory epithelium
وصف الملف: application/octet-stream
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المؤلفون: Vishukumar Aimanianda, Jacob L. Steenwyk, Agostinho Carvalho, Cláudio Duarte-Oliveira, Laure Nicolas Annick Ries, Fernando Rodrigues, Fausto Almeida, Taicia Pacheco Fill, Antonis Rokas, Lilian Pereira Silva, Patrícia Alves de Castro, Iola F. Duarte, Sarah Sze Wah Wong, Jonas Henrique Costa, Gustavo H. Goldman, Clara Valero, Relber Aguiar Gonçales, Raquel Saborano, Gabriela F. Persinoti, Thaila Fernanda dos Reis
المساهمون: Universidade de São Paulo = University of São Paulo (USP), University of Birmingham [Birmingham], Universidade de Aveiro, Centro Nacional de Pesquisa em Energia e Materiais = Brazilian Center for Research in Energy and Materials (CNPEM), Vanderbilt University [Nashville], Universidade Estadual de Campinas = University of Campinas (UNICAMP), Mycologie moléculaire - Molecular Mycology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Universidade do Minho = University of Minho [Braga], Life and Health Sciences Research Institute [Braga] (ICVS), University of Minho [Braga], We thank Universidade do Minho, Portugal and Universidade do São Paulo, Brazil for providing support for the scientific collaboration (G.H.G. and A.C., Edital USP-UMinho 2019). We thank the São Paulo Research Foundation (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [FAPESP], Brazil) grants 2017/14159-2 (L.N.A.R.), 2016/12948-7 (P.A.D.C.), 2017/08750-0 (T.F.D.R.), 2016/07870-9 (G.H.G.), 2018/00715-3 (C.V.), and the Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil (CNPq) grants 301058/2019-9 and 404735/2018-5 (G.H.G.) for financial support. I.F.D. acknowledges CICECO-Aveiro Institute of Materials (UIDB/50011/2020 and UIDP/50011/2020) financed by national funds through the Foundation for Science and Technology/MCTES, and the National NMR Network (PTNMR) partially supported by Infrastructure Project 022161 (cofinanced by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC). A.C., R.A.G., and C.D.-O. were supported by the Fundação para a Ciência e a Tecnologia (FCT) (PTDC/MED-GEN/28778/2017, UIDB/50026/2020, and UIDP/50026/2020). Additional support was provided by the Northern Portugal Regional Operational Program (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF) (NORTE-01-0145-FEDER-000013 and NORTE-01-0145-FEDER-000023), the European Union’s Horizon 2020 research and innovation program under grant agreement 847507, and the 'la Caixa' Foundation (ID 100010434) and FCT under the agreement LCF/PR/HP17/52190003. Individual support was provided by FCT (SFRH/BD/141127/2018 to C.D.-O., and CEECIND/03628/2017 to A.C.). This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001 (J.H.C. scholarship). S.S.W.W. was supported by Pasteur-Roux-Cantarini fellowship. J.L.S. and A.R. are supported by the Howard Hughes Medical Institute through the James H. Gilliam Fellowships for Advanced Study program, A.R. is additionally supported by the National Institutes of Health/National Institute of Allergy and Infectious Diseases (1R56AI146096-01A1)., European Project: 847507,H2020-SC1-2019-Two-Stage-RTD,HDM-FUN(2020)
المصدر: mBio
mBio, 2021, 12 (4), pp.e0168221. ⟨10.1128/mBio.01682-21⟩
mBio, Vol 12, Iss 4 (2021)مصطلحات موضوعية: Male, Neutrophils, Secondary Metabolism, Acetates, Moths, MESH: Neutrophils, MESH: Virulence, Aspergillus fumigatus, Mice, Gene Expression Regulation, Fungal, MESH: Animals, skin and connective tissue diseases, transcription factor, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, 0303 health sciences, Virulence, biology, secondary metabolites, MESH: Moths, QR1-502, MESH: Secondary Metabolism, Phenotype, Larva, acetate assimilation, MESH: Fungal Proteins, MESH: Acetates, MESH: Aspergillus fumigatus, Acetate utilization, MESH: Gene Expression Regulation, Fungal, Research Article, MESH: Phenotype, Microbiology, Fungal Proteins, 03 medical and health sciences, MESH: Mice, Inbred C57BL, Virology, Animals, Aspergillosis, Humans, MESH: Aspergillosis, Transcription factor, MESH: Mice, 030304 developmental biology, Final version, MESH: Humans, 030306 microbiology, biology.organism_classification, Pathogenicity, MESH: Male, Mice, Inbred C57BL, cell wall, MESH: Larva
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المؤلفون: Sophie Vinoy, Carlito B. Lebrilla, Jeffrey I. Gordon, Kyleigh Kirbach, Andrew C. Heath, Bernard Henrissat, Chandani Desai, Juan Jose Castillo, Ruteja A. Barve, Omar Delannoy-Bruno, Arjun S. Raman, Robert Y. Chen, David K. Hayashi, Andrei L. Osterman, Semen A. Leyn, Nathan D. Han, Jiye Cheng, Matthew C. Hibberd, Dmitry A. Rodionov, Alexandra Meynier, Garret Couture, Vincent Lombard, Tara Wilmot, Samuel Klein, Michael J. Barratt
المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
المصدر: Nature
Nature, Nature Publishing Group, 2021, 595 (7865), pp.91-95. ⟨10.1038/s41586-021-03671-4⟩
Nature, vol 595, iss 7865
Nature, 2021, 595 (7865), pp.91-95. ⟨10.1038/s41586-021-03671-4⟩مصطلحات موضوعية: 0301 basic medicine, Dietary Fiber, Male, Proteome, [SDV]Life Sciences [q-bio], Disease, Overweight, MESH: Bacteroides, Inbred C57BL, Cardiovascular, Oral and gastrointestinal, Feces, Mice, 0302 clinical medicine, MESH: Blood Proteins, Bacteroides, MESH: Obesity, MESH: Animals, Food science, Cancer, 2. Zero hunger, Multidisciplinary, MESH: Middle Aged, Human studies, digestive, oral, and skin physiology, MESH: Feces, Blood Proteins, Middle Aged, 3. Good health, Stroke, MESH: Proteome, MESH: Young Adult, Female, Zero Hunger, medicine.symptom, MESH: Snacks, Adult, Adolescent, General Science & Technology, Biology, MESH: Gastrointestinal Microbiome, 03 medical and health sciences, Young Adult, MESH: Mice, Inbred C57BL, Controlled diets, MESH: Germ-Free Life, medicine, Animals, Humans, Germ-Free Life, Microbiome, Obesity, MESH: Overweight, MESH: Mice, Metabolic and endocrine, Nutrition, MESH: Adolescent, MESH: Humans, Prevention, Dietary fibre, MESH: Adult, medicine.disease, MESH: Male, Gastrointestinal Microbiome, 030104 developmental biology, MESH: Dietary Fiber, Snacks, MESH: Female, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Pierre De Rossi, Marian Hruska-Plochan, Magdalini Polymenidou, Mark D. Robinson, Elena Tantardini, Luc Dupuis, Salim Megat, Julien Weber, Katharina M. Hembach, Petra Schwarz, Sonu Sahadevan, Manuela Pérez-Berlanga
المساهمون: Universität Zürich [Zürich] = University of Zurich (UZH), Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), University hospital of Zurich [Zurich], Dieterle, Stéphane, University of Zurich, Polymenidou, Magdalini
المصدر: Nature Communications
Nature Communications, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], General Physics and Astronomy, MESH: Synapses, Synapse, Mice, 0302 clinical medicine, MESH: Animals, Amyotrophic lateral sclerosis, MESH: Amyotrophic Lateral Sclerosis, Cerebral Cortex, Multidisciplinary, MESH: RNA-Binding Protein FUS, Neurodegeneration, 10124 Institute of Molecular Life Sciences, 3100 General Physics and Astronomy, Cell biology, [SDV] Life Sciences [q-bio], GABAergic, Microtubule-Associated Proteins, MESH: Cell Nucleus, Science, 1600 General Chemistry, Genetics and Molecular Biology, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 1300 General Biochemistry, Genetics and Molecular Biology, MESH: Mice, Inbred C57BL, MESH: RNA, medicine, Animals, RNA, Messenger, Synapse organization, MESH: Mice, MESH: RNA, Messenger, RNA metabolism, Cell Nucleus, Messenger RNA, Amyotrophic Lateral Sclerosis, RNA, General Chemistry, medicine.disease, MESH: Cerebral Cortex, Mice, Inbred C57BL, MESH: Microtubule-Associated Proteins, Disease Models, Animal, 030104 developmental biology, General Biochemistry, Synapses, 570 Life sciences, biology, RNA-Binding Protein FUS, MESH: Disease Models, Animal, 11493 Department of Quantitative Biomedicine, 030217 neurology & neurosurgery, Nuclear localization sequence
وصف الملف: application/pdf; s41467-021-23188-8.pdf - application/pdf
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المؤلفون: Scott, Jan, Etain, Bruno, Nierenberg, Andrew, Bellivier, Frank
المساهمون: Newcastle University [Newcastle], Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S_1144 / U1144)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpitaux Universitaire Saint-Louis, Lariboisière, Fernand-Widal, Massachusetts General Hospital [Boston], Harvard Medical School [Boston] (HMS), Etain, Bruno
المصدر: Bipolar Disorders
Bipolar Disorders, Wiley, 2021, Current Topics in Behavioral Neurosciences, 23 (1), pp.24-32. ⟨10.1111/bdi.12950⟩مصطلحات موضوعية: MESH: Swimming, MESH: Humans, MESH: Psychotropic Drugs, MESH: Metabolic Syndrome, shared decision making, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, MESH: Antimanic Agents, clinical response, MESH: Immobilization, MESH: Male, mood stabilizers, taxonomy, MESH: Anticonvulsants, MESH: Mice, Inbred C57BL, MESH: Bipolar Disorder, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, MESH: Feeding Behavior, MESH: Mental Disorders, MESH: Consensus, clinical practice guidelines, MESH: Receptors, GABA-A
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المؤلفون: Asma Cherait, Julie Maucotel, Benjamin Lefranc, Jérôme Leprince, David Vaudry
المساهمون: Lebon, Alexis, Différenciation et communication neuronale et neuroendocrine (DC2N), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Algiers 3 : Université d' Alger 3, Plate-Forme de Recherche en Imagerie Cellulaire de Haute-Normandie (PRIMACEN), Normandie Université (NU)-Normandie Université (NU)-Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-High-tech Research Infrastructures for Life Sciences (HeRacLeS), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology, 2021, 11, pp.585082. ⟨10.3389/fendo.2020.585082⟩مصطلحات موضوعية: Male, 0301 basic medicine, Nasal cavity, functional recovery, Endocrinology, Diabetes and Metabolism, MESH: Neurotransmitter Agents, Pharmacology, infarct volume, lcsh:Diseases of the endocrine glands. Clinical endocrinology, cerebral ischemia, Mice, Endocrinology, 0302 clinical medicine, [CHIM] Chemical Sciences, MESH: Animals, MESH: Administration, Intranasal, Middle cerebral artery occlusion, Original Research, Neurotransmitter Agents, MESH: Infarction, Middle Cerebral Artery, Infarction, Middle Cerebral Artery, MESH: Neuroprotective Agents, MESH: Recovery of Function, pituitary adenylate cyclase-activating polypeptide, Neuroprotective Agents, medicine.anatomical_structure, Infarct volume, Brain Infarction, Central nervous system, Ischemia, Neuroprotection, intranasal administration, 03 medical and health sciences, MESH: Brain Infarction, MESH: Mice, Inbred C57BL, medicine, [CHIM]Chemical Sciences, Animals, MESH: Mice, Administration, Intranasal, lcsh:RC648-665, business.industry, MESH: Pituitary Adenylate Cyclase-Activating Polypeptide, Recovery of Function, medicine.disease, Functional recovery, MESH: Male, Mice, Inbred C57BL, 030104 developmental biology, Nasal administration, business, 030217 neurology & neurosurgery
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المؤلفون: Nathalie Boulet, Jan Nedergaard, Barbara Cannon, Ineke H.N. Luijten
المساهمون: boulet, nathalie, Stockholm University
المصدر: AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, 2021, 320 (2), pp.E359-E378. ⟨10.1152/ajpendo.00352.2020⟩
American Journal of Physiology-Endocrinology and Metabolismمصطلحات موضوعية: 0301 basic medicine, Male, obesity, Physiology, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], Adipose tissue, MESH: Adipose Tissue, Beige, MESH: Mice, Knockout, Mice, MESH: Uncoupling Protein 1, 0302 clinical medicine, Adipose Tissue, Brown, Brown adipose tissue, Macrophage, MESH: Obesity, MESH: Thermogenesis, MESH: Animals, Biological sciences, Uncoupling Protein 1, Mice, Knockout, Thermogenesis, MESH: Gene Expression Regulation, macrophages, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Research Article, medicine.medical_specialty, Biology, MESH: Adipose Tissue, Brown, 03 medical and health sciences, MESH: Diet, MESH: Mice, Inbred C57BL, Physiology (medical), Internal medicine, medicine, Animals, MESH: Mice, MESH: Macrophages, brown adipose tissue, Adipose Tissue, Beige, cold, MESH: Male, Diet, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Receptors, Adrenergic, beta-2, MESH: Receptors, Adrenergic, beta-1, Receptors, Adrenergic, beta-1, MESH: Receptors, Adrenergic, beta-2, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Rosemary Sang, Martin N. Mayanja, Van-Mai Cao-Lormeau, Julius J. Lutwama, Fabien Aubry, Oumar Faye, Veasna Duong, Louis Lambrechts, Sampson Otoo, Isabelle Dusfour, Elliott F. Miot, Joel Lutomiah, John-Paul Mutebi, Alain Kohl, Caroline Manet, Anna B. Crist, Artem Baidaliuk, Xavier Montagutelli, Alongkot Ponlawat, Sarah H. Merkling, Igor Filipović, Christophe Paupy, Claudia M. E. Romero-Vivas, Jewelna Akorli, Noah H. Rose, Cheikh Tidiane Diagne, Anubis Vega-Rúa, Richard G. Jarman, Laura B. Dickson, Ousmane Faye, Davy Jiolle, Victor O. Anyango, Carolyn S. McBride, Gordana Rašić, Daria Martynow, Stéphanie Dabo, Massamba Sylla, Amadou A. Sall
المساهمون: Interactions Virus-Insectes - Insect-Virus Interactions (IVI), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Génétique de la souris - Mouse Genetics, Institut Pasteur [Paris], QIMR Berghofer Medical Research Institute, Princeton University, Collège doctoral [Sorbonne universités], Sorbonne Université (SU), Universidad del Norte, Barranquilla, Unité Transmission, Réservoir et Diversité des Pathogènes [Pasteur Guadeloupe, France] (TReD-Path), Institut Pasteur de la Guadeloupe, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Vectopôle Amazonien Emile Abonnenc [Cayenne, Guyane française], Institut Pasteur de la Guyane, Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Centre International de Recherches Médicales de Franceville (CIRMF), Uganda Virus Research Institute (UVRI), MRC - University of Glasgow Centre for Virus Research, Unité de Virologie / Virology Unit [Phnom Penh], Institut Pasteur du Cambodge, Armed Forces Research Institute of Medical Sciences [Bangkok] (AFRIMS), Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD), University of Ghana, Kenya Medical Research Institute (KEMRI), Centers for Disease Control and Prevention, Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD), Walter Reed Army Institute of Research, Arbovirus et Virus de Fièvres Hémorragiques [Dakar, Sénégal], Institut Pasteur de Dakar, This work was primarily funded by the European Union’s Horizon 2020 research and innovation programme under ZikaPLAN grant agreement no. 734584 (to L.L.). This work was also supported by Agence Nationale de la Recherche (grants ANR-16-CE35-0004-01, ANR-17-ERC2-0016-01, and ANR-18-CE35-0003-01 to L.L.), the French Government’s Investissement d’Avenir program Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (grant ANR-10-LABX-62-IBEID to L.L. and X.M.), the Inception program (Investissement d’Avenir grant ANR-16-CONV-0005 to L.L.), the City of Paris Emergence(s) program in Biomedical Research (to L.L.), the QIMR Berghofer Medical Research Institute (Seed Funding Grant to G.R.), the Programme Opérationnel FEDER-Guadeloupe-Conseil Régional 2014-2020 (grant 2015-FED-192 to A.V.-R.), the European Union's Horizon 2020 research and innovation programme under ZIKALLIANCE grant agreement no. 734548 (to A.V.-R.), the U.S. National Institutes of Health (grant NIDCD R00-DC012069 to C.S.M.), a Helen Hay Whitney Postdoctoral Fellowship (to N.H.R.), the UK Medical Research Council (grant MC_UU_12014/8 to A.K.), and the CDC (J.-P.M.). C.S.M. is a New York Stem Cell Foundation—Robertson Investigator., ANR-16-CE35-0004,MOSQUIBIOTA,Contribution de la diversité bactérienne intestinale à la capacité vectorielle d'Aedes aegypti(2016), ANR-17-ERC2-0016,GxG,Base génétique de la spécificité génotype-génotype dans l'interaction naturelle entre un virus et son insecte vecteur(2017), ANR-18-CE35-0003,BAKOUMBA,Dissection de la base génétique d'un phénotype naturel de résistance à la dengue chez le moustique Aedes aegypti(2018), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-16-CONV-0005,INCEPTION,Institut Convergences pour l'étude de l'Emergence des Pathologies au Travers des Individus et des populatiONs(2016), European Project: 734584,ZikaPLAN, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Collège Doctoral
المصدر: Science
Science, American Association for the Advancement of Science, 2020, 370 (6519), pp.991-996. ⟨10.1126/science.abd3663⟩
Science, 2020, 370 (6519), pp.991-996. ⟨10.1126/science.abd3663⟩مصطلحات موضوعية: viruses, [SDV]Life Sciences [q-bio], 030231 tropical medicine, Population, Zoology, Human pathogen, MESH: Zika Virus, Aedes aegypti, MESH: Host Microbial Interactions, Arbovirus, Zika virus, 03 medical and health sciences, 0302 clinical medicine, MESH: Zika Virus Infection, MESH: Mice, Inbred C57BL, Out of africa, parasitic diseases, medicine, MESH: Animals, Zoonotic virus, education, MESH: Mice, 030304 developmental biology, 0303 health sciences, education.field_of_study, Multidisciplinary, MESH: Humans, biology, fungi, virus diseases, MESH: Aedes, biology.organism_classification, medicine.disease, 3. Good health, Vector (epidemiology), MESH: Mosquito Vectors
وصف الملف: application/pdf
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المؤلفون: Stanislas Goriely, Marie-Véronique Joubert, Tobias Bald, Mark J. Smyth, Ludovic Martinet, Elena Morandi, Loïc Dupré, Laure Buisson, Nadège Carrié, Marianne Weulersse, Guillaume Gaud, Marie Le Moine, Thomas Gossye, Anne Dejean, Hervé Avet-Loiseau, Ashmitha Sundarrajan, Assia Asrir, Andrea C. Pichler, Michaël Pérès, Abdelhadi Saoudi, Alejandra Martinez, Julien Mazieres, Sahar Kassem, Elisa Brauns, Els Verhoeyen, Indrajit Das, Sabrina Maheo, Matthias Braun, Vera Pancaldi, Clara Maria Scarlata, Marine Cuisinier, Maha Ayyoub, Laura Do Souto, Lea Lemaitre, Arantxa Agesta, Camille Guillerey
المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), QIMR Berghofer Medical Research Institute, Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université libre de Bruxelles (ULB), Centre de Physiopathologie Toulouse Purpan (CPTP), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Centre International de Recherche en Infectiologie - UMR (CIRI), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Barcelona Supercomputing Center - Centro Nacional de Supercomputacion (BSC - CNS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Nice Sophia Antipolis (1965 - 2019) (UNS), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Physiopathologie Toulouse Purpan ex IFR 30 et IFR 150 (CPTP)
المصدر: Immunity, 53 (4
Immunity
Immunity, Elsevier, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩
Immunity, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩مصطلحات موضوعية: 0301 basic medicine, MESH: Neoplasms / immunology, 8 Supplementary Figures, Lymphocyte, medicine.medical_treatment, [SDV]Life Sciences [q-bio], MESH: Programmed Cell Death 1 Receptor / immunology, CD226 (DNAM-1), MESH: Receptors, Antigen, T-Cell / immunology, MESH: Neoplasms / therapy, TCR signaling, 0302 clinical medicine, Cancer immunotherapy, MESH: Tumor Necrosis Factor Receptor Superfamily, Member 9 / immunology, Immunology and Allergy, Cytotoxic T cell, MESH: Animals, ComputingMilieux_MISCELLANEOUS, T cell exhaustion, MESH: Signal Transduction / immunology, MESH: CD8-Positive T-Lymphocytes / immunology, 3. Good health, Infectious Diseases, medicine.anatomical_structure, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, 030220 oncology & carcinogenesis, Immunotherapy, MESH: Transcriptome / immunology, Immunology, Eomesodermin, 8 Figures, Biology, MESH: Antigens, Differentiation, T-Lymphocyte / immunology, Co-stimulation, 03 medical and health sciences, tumor immune escape, MESH: Mice, Inbred C57BL, MESH: Immune Checkpoint Inhibitors / immunology, medicine, MESH: Tumor Microenvironment / immunology, MESH: Mice, 96 References CD8 + T lymphocytes, Tumor microenvironment, MESH: Humans, immune checkpoint blockade, MESH: T-Box Domain Proteins / immunology, Immune checkpoint, MESH: Immunotherapy / methods, Sciences biomédicales, 030104 developmental biology, Cancer research, CD8
وصف الملف: 1 full-text file(s): application/pdf
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المؤلفون: Martin, Pierre-Yves, Doly, Stéphane, Hamieh, Al Mahdy, Chapuy, Eric, Canale, Vittorio, Drop, Marcin, Chaumont-Dubel, Séverine, Bantreil, Xavier, Lamaty, Frédéric, Bojarski, Andrzej, Zajdel, Pawel, Eschalier, Alain, Marin, Philippe, COURTEIX, Christine
المساهمون: Neuro-Dol (Neuro-Dol), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM), ANR-17-CE16-0010,Sero6Dev,Réseau de signalisation associé au récepteur 5-HT6 et développement neuronal(2017), ANR-17-CE16-0013,StopSero6TOR,La signalisation mTOR induite par le récepteur 5-HT6 comme cible thérapeutique pour prévenir l'apparition des déficits cognitifs dans la schizophrénie(2017), ANR-19-CE18-0018,SERO6Pain,Les voies de signalisation du récepteur 5-HT6: de nouvelles cibles pour le traitement de la douleur neuropathique?(2019), COURTEIX, Christine, Réseau de signalisation associé au récepteur 5-HT6 et développement neuronal - - Sero6Dev2017 - ANR-17-CE16-0010 - AAPG2017 - VALID, La signalisation mTOR induite par le récepteur 5-HT6 comme cible thérapeutique pour prévenir l'apparition des déficits cognitifs dans la schizophrénie - - StopSero6TOR2017 - ANR-17-CE16-0013 - AAPG2017 - VALID, Les voies de signalisation du récepteur 5-HT6: de nouvelles cibles pour le traitement de la douleur neuropathique? - - SERO6Pain2019 - ANR-19-CE18-0018 - AAPG2019 - VALID, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA), Université Clermont Auvergne (UCA)
المصدر: Progress in Neurobiology
Progress in Neurobiology, Elsevier, 2020, 193, pp.101846. ⟨10.1016/j.pneurobio.2020.101846⟩
Progress in Neurobiology, 2020, 193, pp.101846. ⟨10.1016/j.pneurobio.2020.101846⟩مصطلحات موضوعية: MESH: Cognitive Dysfunction/drug therapy, Male, Nociception, MESH: Neuralgia/drug therapy, [SDV]Life Sciences [q-bio], [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, MESH: Hyperalgesia/drug therapy, MESH: Rats, Sprague-Dawley, MESH: Nociception/drug effects, Neuropathic pain, MESH: Neuralgia/complications, Rats, Sprague-Dawley, Serotonin Agents, MESH: Animals, MESH: Receptors, Serotonin/drug effects, Neuropathic pain Cognitive deficit 5-HT6 receptor Constitutive activity mTOR Inverse agonist, Behavior, Animal, TOR Serine-Threonine Kinases, MESH: Hyperalgesia/metabolism, MESH: Cognitive Dysfunction/metabolism, [SDV] Life Sciences [q-bio], MESH: Serotonin Agents/pharmacology, Hyperalgesia, MESH: HEK293 Cells, mTOR, MESH: Neuralgia/metabolism, Inverse agonist, MESH: Serotonin Agents/administration & dosage, MESH: Behavior Animal/drug effects, MESH: Rats, MESH: Mice, Transgenic, MESH: Cognitive Dysfunction/etiology, Mice, Transgenic, MESH: TOR Serine-Threonine Kinases/metabolism, Constitutive activity, MESH: Mice, Inbred C57BL, Animals, Humans, Cognitive Dysfunction, MESH: Humans, Cognitive deficit, MESH: Receptors, Serotonin/metabolism, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, MESH: TOR Serine-Threonine Kinases/drug effects, MESH: Male, Rats, Mice, Inbred C57BL, Disease Models, Animal, HEK293 Cells, 5-HT6 receptor, Receptors, Serotonin, Neuralgia, MESH: Disease Models, Animal
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المؤلفون: Christian Njoo, Stefan G. Lechner, Mirko Moroni, Francisco J. Taberner, Faramarz Faghihi, Daniel Rangel Rojas, Thomas Fleming, Alexandra Andrieux, Nitin Agarwal, Gary R. Lewin, Pooja Gupta, Kiran Kumar Bali, Anne Dejean, Esther Herpel, Rohini Kuner, Peter P. Nawroth, Damir Omberbasic
المساهمون: Heidelberg University, Max Delbrück Center for Molecular Medicine [Berlin] (MDC), Helmholtz-Gemeinschaft = Helmholtz Association, Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Heidelberg University Hospital [Heidelberg], This work was supported by Deutsche Forschungsgemeinschaft grants SFB1118 (project B06) (to N.A. and R.K.), SFB1118 (projects A04, S02, and S01) (to P.P.N., E.H., and T.F.), SFB1158 (project A01) (to S.G.L.), and SFB1158 (project A03) (to P.P.N.). R.K. is a member of the Molecular Medicine Partnership Unit, Heidelberg and a principal investigator in the Excellence Cluster 'CellNetworks' of Heidelberg University., The authors are grateful to D. Baumgartl-Ahlert for technical assistance. We acknowledge support from the Interdisciplinary Neurobehavioral Core (INBC), the Proteomics facility, and the Metabolomics facility at Heidelberg University. We acknowledge support from the tissue bank of the National Centre for Tumour Diseases (NCT, Heidelberg, Germany) in accordance with the regulations of the tissue bank and approval from the ethics committee of Heidelberg University (Ethic Votes 206/2005 and 207/2005)., Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Neuron
Neuron, 2020, 107 (6), pp.1141-1159.e7. ⟨10.1016/j.neuron.2020.06.037⟩
Neuron, Elsevier, 2020, 107 (6), pp.1141-1159.e7. ⟨10.1016/j.neuron.2020.06.037⟩مصطلحات موضوعية: 0301 basic medicine, Male, Nociception, Diabetic neuropathy, MESH: Nociception, [SDV]Life Sciences [q-bio], SUMO protein, Mice, 0302 clinical medicine, Diabetic Neuropathies, MESH: Sensory Receptor Cells, Ganglia, Spinal, MESH: Animals, Cells, Cultured, General Neuroscience, MESH: Sumoylation, 3. Good health, MESH: HEK293 Cells, MESH: Glycolysis, Female, MESH: Ganglia, Spinal, Glycolysis, MESH: Cells, Cultured, Sensory Receptor Cells, Citric Acid Cycle, TRPV1, TRPV Cation Channels, Sensory system, Neuropathology, 03 medical and health sciences, MESH: Citric Acid Cycle, MESH: Mice, Inbred C57BL, Diabetes mellitus, medicine, Animals, Humans, MESH: Mice, MESH: Humans, business.industry, MESH: Diabetic Neuropathies, Sumoylation, medicine.disease, MESH: Male, Mice, Inbred C57BL, Metabolic pathway, 030104 developmental biology, Peripheral neuropathy, HEK293 Cells, MESH: TRPV Cation Channels, MESH: Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), business, Neuroscience, MESH: Female, 030217 neurology & neurosurgery